메뉴 건너뛰기




Volumn 4, Issue 6, 1999, Pages 353-362

Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR;

EID: 6544270833     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1999.00265.x     Document Type: Article
Times cited : (562)

References (43)
  • 1
    • 0032127279 scopus 로고    scopus 로고
    • Targeted disruption of the MyD88 gene results in loss of IL-1- and IL- 18-mediated function
    • Adachi, O., Kawai, T., Takeda, K., et al. (1998) Targeted disruption of the MyD88 gene results in loss of IL-1- and IL- 18-mediated function. Immunity 9, 143-150.
    • (1998) Immunity , vol.9 , pp. 143-150
    • Adachi, O.1    Kawai, T.2    Takeda, K.3
  • 2
    • 0030714605 scopus 로고    scopus 로고
    • A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
    • Anderson, D.M., Maraskovsky, E., Billingsley, W.L., et al. (1997) A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390, 175-179.
    • (1997) Nature , vol.390 , pp. 175-179
    • Anderson, D.M.1    Maraskovsky, E.2    Billingsley, W.L.3
  • 3
    • 0032530455 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor-associated factors (TRAFs) - A family of adapter proteins that regulates life and death
    • Arch., R.H., Gedrich, R.W. & Thompson, C.B. (1998) Tumor necrosis factor receptor-associated factors (TRAFs) - a family of adapter proteins that regulates life and death. Genes Dev. 12, 2821-2830.
    • (1998) Genes Dev. , vol.12 , pp. 2821-2830
    • Arch, R.H.1    Gedrich, R.W.2    Thompson, C.B.3
  • 4
    • 0029761275 scopus 로고    scopus 로고
    • TRAF6 is a signal transducer for interleukin-1
    • Cao, Z., Xiong, J., Takeuchi, M., Kurama, T. & Goeddel, D.V. (1996) TRAF6 is a signal transducer for interleukin-1. Nature 383, 443-446.
    • (1996) Nature , vol.383 , pp. 443-446
    • Cao, Z.1    Xiong, J.2    Takeuchi, M.3    Kurama, T.4    Goeddel, D.V.5
  • 6
    • 0032493737 scopus 로고    scopus 로고
    • Characterization of the intracellular domain of receptor activator of NF-κB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-κB and c-Jun N-terminal kinase
    • Darnay, B.G., Haridas, V., Ni, J., Moore, P.A. & Aggarwal, B.B. (1998) Characterization of the intracellular domain of receptor activator of NF-κB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-κB and c-Jun N-terminal kinase. J. Biol. Chem. 273, 20551-20555.
    • (1998) J. Biol. Chem. , vol.273 , pp. 20551-20555
    • Darnay, B.G.1    Haridas, V.2    Ni, J.3    Moore, P.A.4    Aggarwal, B.B.5
  • 7
    • 15444357762 scopus 로고    scopus 로고
    • Requirement for NF-κB in osteoclast and B-cell development
    • Franzoso, G., Carlson, L., Xing, L., et al. (1997) Requirement for NF-κB in osteoclast and B-cell development. Genes Dev. 11, 3482-3496.
    • (1997) Genes Dev. , vol.11 , pp. 3482-3496
    • Franzoso, G.1    Carlson, L.2    Xing, L.3
  • 8
    • 0032545465 scopus 로고    scopus 로고
    • The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-κB, a member of the TNFR superfamily
    • Galibert, L., Tometsko, M.E., Anderson, D.M., Cosman, D. & Dougall, W.C. (1998) The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-κB, a member of the TNFR superfamily. J. Biol. Chem. 273, 34120-34127.
    • (1998) J. Biol. Chem. , vol.273 , pp. 34120-34127
    • Galibert, L.1    Tometsko, M.E.2    Anderson, D.M.3    Cosman, D.4    Dougall, W.C.5
  • 9
    • 0027153201 scopus 로고
    • A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression
    • Godfrey, D.I., Kennedy, J., Suda, T. & Zlotnik, A. (1993) A developmental pathway involving four phenotypically and functionally distinct subsets of CD3-CD4-CD8-triple-negative adult mouse thymocytes defined by CD44 and CD25 expression. J. Immunol 150, 4244-4252.
    • (1993) J. Immunol , vol.150 , pp. 4244-4252
    • Godfrey, D.I.1    Kennedy, J.2    Suda, T.3    Zlotnik, A.4
  • 10
    • 0028173214 scopus 로고
    • c-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling
    • Grigoriadis, A.E., Wang, Z.Q., Cecchini, M.G., et al. (1994) c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 266, 443-448.
    • (1994) Science , vol.266 , pp. 443-448
    • Grigoriadis, A.E.1    Wang, Z.Q.2    Cecchini, M.G.3
  • 11
    • 0027943499 scopus 로고
    • A novel RING finger protein interacts with the cytoplasmic domain of CD40
    • Hu, H.M., O'Rourke, K., Boguski, M.S. & Dixit, V.M. (1994) A novel RING finger protein interacts with the cytoplasmic domain of CD40. J. Biol. Chem. 269, 30069-30072.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30069-30072
    • Hu, H.M.1    O'Rourke, K.2    Boguski, M.S.3    Dixit, V.M.4
  • 13
    • 10544243364 scopus 로고    scopus 로고
    • Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region
    • Ishida, T., Mizushima, S., Azuma, S., et al. (1996a) Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J. Biol. Chem. 271, 28745-28748.
    • (1996) J. Biol. Chem. , vol.271 , pp. 28745-28748
    • Ishida, T.1    Mizushima, S.2    Azuma, S.3
  • 14
    • 0029847814 scopus 로고    scopus 로고
    • TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling
    • Ishida, T.K., Tojo, T., Aoki, T., et al. (1996b) TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling. Proc. Natl. Acad. Sci. USA 93, 9437-9442.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9437-9442
    • Ishida, T.K.1    Tojo, T.2    Aoki, T.3
  • 15
    • 0028447437 scopus 로고
    • The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
    • Kawabe, T., Naka, T., Yoshida, K., et al. (1994) The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity 1, 167-178.
    • (1994) Immunity , vol.1 , pp. 167-178
    • Kawabe, T.1    Naka, T.2    Yoshida, K.3
  • 16
    • 0033611467 scopus 로고    scopus 로고
    • OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
    • Kong, Y.Y., Yoshida, H., Sarosi, I., et al. (1999) OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397, 315-323.
    • (1999) Nature , vol.397 , pp. 315-323
    • Kong, Y.Y.1    Yoshida, H.2    Sarosi, I.3
  • 17
    • 0031227868 scopus 로고    scopus 로고
    • Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice
    • Labow, M., Shuster, D., Zetterstrom, M., et al. (1997) Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice. J. Immunol. 159, 2452-2461.
    • (1997) J. Immunol. , vol.159 , pp. 2452-2461
    • Labow, M.1    Shuster, D.2    Zetterstrom, M.3
  • 18
    • 0032540319 scopus 로고    scopus 로고
    • Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
    • Lacey, D.L., Timms, E., Tan, H.L., et al. (1998) Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93, 165-176.
    • (1998) Cell , vol.93 , pp. 165-176
    • Lacey, D.L.1    Timms, E.2    Tan, H.L.3
  • 19
    • 0033561039 scopus 로고    scopus 로고
    • TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
    • Lomago, M.A., Yeh, W.-C., Sarosi, I., et al. (1999) TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev. 13, 1015-1024.
    • (1999) Genes Dev. , vol.13 , pp. 1015-1024
    • Lomago, M.A.1    Yeh, W.-C.2    Sarosi, I.3
  • 20
    • 0020315821 scopus 로고
    • Bone acid phosphatase: Tartrate-resistant acid phosphatase as a marker of osteoclast function
    • Minkin, C. (1982) Bone acid phosphatase: tartrate-resistant acid phosphatase as a marker of osteoclast function. Calcif. Tissue Int. 34, 285-290.
    • (1982) Calcif. Tissue Int. , vol.34 , pp. 285-290
    • Minkin, C.1
  • 22
    • 0028878977 scopus 로고
    • The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
    • Mosialos, G., Birkenbach, M., Yalamanchili, R., VanArsdale, T., Ware, C. & Kieff, E. (1995) The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family. Cell 80, 389-399.
    • (1995) Cell , vol.80 , pp. 389-399
    • Mosialos, G.1    Birkenbach, M.2    Yalamanchili, R.3    VanArsdale, T.4    Ware, C.5    Kieff, E.6
  • 23
    • 0032526861 scopus 로고    scopus 로고
    • The human toll signaling pathway: Divergence of nuclear factor KB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)
    • Muzio, M., Natoli, G., Saccani, S., Levrero, M. & Mantovani, A. (1998) The human toll signaling pathway: divergence of nuclear factor KB and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6). J. Exp. Med. 187, 2097-2101.
    • (1998) J. Exp. Med. , vol.187 , pp. 2097-2101
    • Muzio, M.1    Natoli, G.2    Saccani, S.3    Levrero, M.4    Mantovani, A.5
  • 24
    • 15844428836 scopus 로고    scopus 로고
    • TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin-β receptor
    • Nakano, H., Oshima, H., Chung, W., et al. (1996) TRAF5, an activator of NF-κB and putative signal transducer for the lymphotoxin-β receptor. J. Biol. Chem. 271, 14661-14664.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14661-14664
    • Nakano, H.1    Oshima, H.2    Chung, W.3
  • 25
    • 0033580466 scopus 로고    scopus 로고
    • The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signaling pathway
    • Ninomiya, T.J., Kishimoto, K., Hiyama, A., Inoue, J., Cao, Z. & Matsumoto, K. (1999) The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signaling pathway. Nature 398, 252-256.
    • (1999) Nature , vol.398 , pp. 252-256
    • Ninomiya, T.J.1    Kishimoto, K.2    Hiyama, A.3    Inoue, J.4    Cao, Z.5    Matsumoto, K.6
  • 26
    • 0032158987 scopus 로고    scopus 로고
    • ASK1 is essential for JNK/SAPK activation by TRAF2
    • Nishitoh, H., Saitoh, M., Mochida, Y., et al. (1998) ASK1 is essential for JNK/SAPK activation by TRAF2. Mol. Cell 2, 389-395.
    • (1998) Mol. Cell , vol.2 , pp. 389-395
    • Nishitoh, H.1    Saitoh, M.2    Mochida, Y.3
  • 27
    • 0028031682 scopus 로고
    • Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment
    • Okada, S., Wang, Z.-Q., Grigodiadis, A.E., Wagner, E.F. & von Rüden, T. (1994) Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment. Mol. Cell. Biol. 14, 382-390.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 382-390
    • Okada, S.1    Wang, Z.-Q.2    Grigodiadis, A.E.3    Wagner, E.F.4    Von Rüden, T.5
  • 28
    • 0028877380 scopus 로고
    • The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development
    • Popoff, S.N. & Marks, S.C. Jr (1995) The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development. Bone 17, 437-445.
    • (1995) Bone , vol.17 , pp. 437-445
    • Popoff, S.N.1    Marks Jr., S.C.2
  • 29
    • 0028856787 scopus 로고
    • Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma
    • Regnier, C.H., Tomasetto, C., Moog-Lutz, C., et al. (1995) Presence of a new conserved domain in CART1, a novel member of the tumor necrosis factor receptor-associated protein family, which is expressed in breast carcinoma. J. Biol. Chem. 270, 25715-25721.
    • (1995) J. Biol. Chem. , vol.270 , pp. 25715-25721
    • Regnier, C.H.1    Tomasetto, C.2    Moog-Lutz, C.3
  • 30
    • 0028978626 scopus 로고
    • TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40
    • Rothe, M., Sarma, V., Dixit, V.M. & Goeddel, D.V. (1995) TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40. Science 269, 1424-1427.
    • (1995) Science , vol.269 , pp. 1424-1427
    • Rothe, M.1    Sarma, V.2    Dixit, V.M.3    Goeddel, D.V.4
  • 31
    • 0028124428 scopus 로고
    • A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
    • Rothe, M., Wong, S.C., Henzel, W.J. & Goeddel, D.V. (1994) A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor. Cell 78, 681-692.
    • (1994) Cell , vol.78 , pp. 681-692
    • Rothe, M.1    Wong, S.C.2    Henzel, W.J.3    Goeddel, D.V.4
  • 32
    • 0028809176 scopus 로고
    • A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40
    • Sato, T., Irie, S. & Reed, J.C. (1995) A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40. FEBS Lett. 358, 113-118.
    • (1995) FEBS Lett. , vol.358 , pp. 113-118
    • Sato, T.1    Irie, S.2    Reed, J.C.3
  • 33
    • 0026023289 scopus 로고
    • Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
    • Soriano, P., Montgomery, C., Geske, R. & Bradley, A. (1991) Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64, 693-702.
    • (1991) Cell , vol.64 , pp. 693-702
    • Soriano, P.1    Montgomery, C.2    Geske, R.3    Bradley, A.4
  • 34
    • 0025230416 scopus 로고
    • Direct effects of 17β-estradiol on trabecular bone in ovariectomized rats
    • Takano-Yamamoto, T. & Rodan, G.A. (1990) Direct effects of 17β-estradiol on trabecular bone in ovariectomized rats. Proc. Natl. Acad. Sci. USA 87, 2172-2176.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 2172-2176
    • Takano-Yamamoto, T.1    Rodan, G.A.2
  • 35
    • 0030933226 scopus 로고    scopus 로고
    • Osteopetrosis in mice lacking haematopoietic transcription factor PU.1
    • Tondravi, M.M., McKercher, S.R., Anderson, K., et al. (1997) Osteopetrosis in mice lacking haematopoietic transcription factor PU.1. Nature 386, 81-84.
    • (1997) Nature , vol.386 , pp. 81-84
    • Tondravi, M.M.1    McKercher, S.R.2    Anderson, K.3
  • 36
    • 0033574051 scopus 로고    scopus 로고
    • Two differently regulated nuclear factor KB activation pathways triggered by the cytoplasmic tail of CD40
    • Tsukamoto, N., Kobayashi, N., Azuma, S., Yamamoto, T. & Inoue, J. (1999) Two differently regulated nuclear factor KB activation pathways triggered by the cytoplasmic tail of CD40. Proc. Natl. Acad. Sci. USA 96, 1234-1239.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 1234-1239
    • Tsukamoto, N.1    Kobayashi, N.2    Azuma, S.3    Yamamoto, T.4    Inoue, J.5
  • 37
    • 0020462249 scopus 로고
    • Hematological characterization of congenital osteopetrosis in op/op mouse: Possible mechanism for abnormal macrophage differentiation
    • Wiktor-Jedrzejckaz, W., Ahmed, A., Szczylik, C. & Skelly, R.R. (1982) Hematological characterization of congenital osteopetrosis in op/op mouse: Possible mechanism for abnormal macrophage differentiation. J. Exp. Med. 156, 1516-1527.
    • (1982) J. Exp. Med. , vol.156 , pp. 1516-1527
    • Wiktor-Jedrzejckaz, W.1    Ahmed, A.2    Szczylik, C.3    Skelly, R.R.4
  • 38
    • 0031439265 scopus 로고    scopus 로고
    • TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor
    • Wong, B.R., Josien, R., Lee, S.Y., et al. (1997) TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. J. Exp. Med. 186, 2075-2080.
    • (1997) J. Exp. Med. , vol.186 , pp. 2075-2080
    • Wong, B.R.1    Josien, R.2    Lee, S.Y.3
  • 39
    • 0032561198 scopus 로고    scopus 로고
    • The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor
    • Wong, B.R., Josien, R., Lee, S.Y., Vologodskaia, M., Steinman, R.M. & Choi, Y. (1998) The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor. J. Biol Chem. 273, 28355-28359.
    • (1998) J. Biol Chem. , vol.273 , pp. 28355-28359
    • Wong, B.R.1    Josien, R.2    Lee, S.Y.3    Vologodskaia, M.4    Steinman, R.M.5    Choi, Y.6
  • 40
    • 0030292777 scopus 로고    scopus 로고
    • Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses
    • Xu, Y., Cheng, G. & Baltimore, D. (1996) Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity 5, 407-415.
    • (1996) Immunity , vol.5 , pp. 407-415
    • Xu, Y.1    Cheng, G.2    Baltimore, D.3
  • 41
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • Yasuda, H., Shima, N., Nakagawa, N., et al. (1998) Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA 95, 3597-3602.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3
  • 42
    • 0031463025 scopus 로고    scopus 로고
    • Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
    • Yeh, W.C., Shahinian, A., Speiser, D., et al. (1997) Early lethality, functional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 7, 715-725.
    • (1997) Immunity , vol.7 , pp. 715-725
    • Yeh, W.C.1    Shahinian, A.2    Speiser, D.3
  • 43
    • 0025332897 scopus 로고
    • The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
    • Yoshida, H., Hayashi, S., Kunisada, T., et al. (1990) The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345, 442-444.
    • (1990) Nature , vol.345 , pp. 442-444
    • Yoshida, H.1    Hayashi, S.2    Kunisada, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.