Involvement of Toll-like receptor 4 in innate immunity to respiratory syncytial virus

Journal of Virology

Volumn 75, Issue 22, 2001, Pages 10730-10737

  Haynes, L M ^a   Moore, D D ^a   Kurt Jones, E A ^a   Finberg, R W ^a   Anderson, L J ^a   Tripp, R A ^a  

^a NATL CENTER FOR INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12; TOLL LIKE RECEPTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GRAM NEGATIVE INFECTION; IMMUNE RESPONSE; IMMUNITY; INFLUENZA VIRUS; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SIGNAL TRANSDUCTION; VIRUS INFECTION;

ANIMALS; ANTIGENS, CD14; CYTOTOXICITY, IMMUNOLOGIC; DROSOPHILA PROTEINS; FEMALE; IMMUNITY, NATURAL; INTERLEUKIN-12; INTERLEUKIN-18; KILLER CELLS, NATURAL; LUNG; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; RECEPTORS, CELL SURFACE; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; T-LYMPHOCYTES, CYTOTOXIC; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0034768425     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.22.10730-10737.2001     Document Type: Article

References (35)

1. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
2. Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2
3. Rapid flow-cytometric assay for the assessment of natural killer cell activity
4. Respiratory syncytial virus (RSV) F, G, M2 (22K), and N proteins each induce resistance to RSV challenge, but resistance induced by M2 and N proteins is relatively short-lived
5. Methods of analyzing chromatin changes accompanying apoptosis of target cells in killer cell assays
6. Generation of atypical pulmonary inflammatory responses in BALB/c mice after immunization with the native attachment (G) glycoproteins of respiratory syncytial virus
7. Inflammatory signaling by Borrelia burgdorferi lipoproteins is mediated by toll-like receptor 2
8. Host genetic determinants of vaccine-induced eosinophilia during respiratory syncytial virus infection
9. Priming with secreted glycoproteins G of respiratory syncytial virus (RSV) augments interleukin-5 production and tissue eosinophilia after RSV challenge
10. Mucosal T cells recovered from mice after infection with respiratory syncytial virus display a memory/activation phenotype
11. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
12. Human Toll-like receptors mediate cellular activation by Mycobacterium tuberculosis
13. Innate immunity: The virtues of a nonclonal system of recognition
14. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
15. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
16. d C57BL/10ScCr mouse
17. Respiratory syncytial virus infection in C57BL/6 mice: Clearance of virus from the lungs with virus-specific cytotoxic T cells
18. Cloning of a new cytokine that induces IFNγ production by T cells
19. IL-18: A novel cytokine that augments both innate and acquired immunity
20. Immunity and immunopathology to respiratory syncytial virus. The mouse model
21. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
22. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4)
23. A family of human receptors structurally related to Drosophila Toll
24. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
25. Immune and histopathological responses in animals vaccinated with recombinant vaccinia viruses that express individual genes of human respiratory syncytial virus
26. Defective NK cell activity and Th1 response in IL-18 deficient mice
27. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components
28. + T cells in respiratory virus infections
29. Respiratory syncytial virus G and/or SH glycoproteins modify CC and CXC chemokine MRNA expression in the BALB/c mouse
30. Respiratory syncytial virus (RSV) G and/or SH proteins alter Th1 cytokines, natural killer cells and neutrophils responding to pulmonary infection in BALB/c mice
31. + T cell response in mice homozygous for disruption of the H-21Ab gene
32. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
33. Genetic control of endotoxin responsiveness: The Lps gene revisted
34. Characterization of a congenitally LPS-resistant, athymic mouse strain
35. IL-12 independent Th1-type immune responses to respiratory viral infection: Requirement of IL-18 for IFNγ release in the lung but not for the differentiation of viral-reactive Th1-type lymphocytes