Endocytosed HSP60s Use Toll-like Receptor 2 (TLR2) and TLR4 to Activate the Toll/Interleukin-1 Receptor Signaling Pathway in Innate Immune Cells

Journal of Biological Chemistry

Volumn 276, Issue 33, 2001, Pages 31332-31339

  Vabulas, Ramunas M ^b   Ahmad Nejad, Parviz ^b   Da Costa, Clarissa ^b   Miethke, Thomas ^b   Kirschning, Carsten J ^b   Häcker, Hans ^b   Wagner, Hermann ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; ENZYME KINETICS; IMMUNOLOGY; PROTEINS;

BIOCHEMICAL PATHWAYS; BIOLOGICAL STRESSES; PATHOGENS;

BIOCHEMISTRY;

HEAT SHOCK PROTEIN 60; I KAPPA B KINASE; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 1 RECEPTOR; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 2; LIGAND; MYELOID DIFFERENTIATION MARKER 88 PROTEIN; PROTEIN; PROTEIN MD 2; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE P38; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CELL SURFACE RECEPTOR; CHAPERONIN; DIFFERENTIATION ANTIGEN; DROSOPHILA PROTEIN; HEAT SHOCK PROTEIN 65, MYCOBACTERIUM; HEAT-SHOCK PROTEIN 65, MYCOBACTERIUM; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; MYD88 PROTEIN, HUMAN; MYD88 PROTEIN, MOUSE; MYELOID DIFFERENTIATION FACTOR 88; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TLR2 PROTEIN, HUMAN; TLR4 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME ACTIVATION; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; IMMUNOGENICITY; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; METABOLISM; PHYSIOLOGY;

ANIMALIA; JANUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; BACTERIAL PROTEINS; CELL LINE; CHAPERONINS; DROSOPHILA PROTEINS; ENDOCYTOSIS; HUMANS; MEMBRANE GLYCOPROTEINS; MICE; MYELOID DIFFERENTIATION FACTOR 88; PROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RECEPTORS, INTERLEUKIN-1; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035903158     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103217200     Document Type: Article

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