Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells

Journal of Biological Chemistry

Volumn 278, Issue 3, 2003, Pages 1561-1568

  Miller, Yury I ^a,c   Viriyakosol, Suganya ^b   Binder, Christoph J ^a   Feramisco, James R ^c   Kirkland, Theo N ^b   Witztum, Joseph L ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION; GENES; MICROORGANISMS; OXIDATION; PROTEINS;

LIPOPROTEINS;

CYTOLOGY;

CD14 ANTIGEN; CELL ANTIGEN; F ACTIN; LOW DENSITY LIPOPROTEIN; TOLL LIKE RECEPTOR 4; ACTIN; BIOPOLYMER; CELL SURFACE RECEPTOR; DROSOPHILA PROTEIN; LY86 PROTEIN, MOUSE; MEMBRANE ANTIGEN; MEMBRANE PROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2;

ACTIN POLYMERIZATION; ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL FUNCTION; CELL SPREADING; CELL TRANSPORT; CELLULAR IMMUNITY; CHINESE HAMSTER; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; LIPID OXIDATION; MACROPHAGE; MOUSE; NONHUMAN; OVARY CELL; PHAGOCYTOSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; ANIMAL; CELL LINE; CHO CELL; CYTOLOGY; HAMSTER; METABOLISM; PHYSIOLOGY;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

ACTINS; ANIMALS; ANTIGENS, CD14; ANTIGENS, SURFACE; APOPTOSIS; BIOPOLYMERS; CELL LINE; CHO CELLS; CRICETINAE; DROSOPHILA PROTEINS; LIPOPROTEINS, LDL; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; PHAGOCYTOSIS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0037449723     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M209634200     Document Type: Article

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