Endotoxin-tolerant mice have mutations in toll-like receptor 4 (Tlr4)

Journal of Experimental Medicine

Volumn 189, Issue 4, 1999, Pages 615-625

  Qureshi, Salman T ^a,b   Larivière, Line ^b   Leveque, Gary ^b   Clermont, Sophie ^b   Moore, Karen J ^c   Gros, Philippe ^a,b   Malo, Danielle ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Inflammation; Lipopolysaccharide; Mice inbred C3H; Positional cloning; Salmonella

Indexed keywords

AMINO ACID; BACTERIUM LIPOPOLYSACCHARIDE; DNA; ENDOTOXIN; HISTIDINE; PROLINE; RECEPTOR; RNA;

ALLELE; AMINO ACID SEQUENCE; ARTICLE; CHROMOSOME 4; GENE; GENE MAPPING; GENE MUTATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SINGLE STRAND CONFORMATION POLYMORPHISM;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; CHROMOSOME MAPPING; CLONING, MOLECULAR; DNA MUTATIONAL ANALYSIS; DROSOPHILA PROTEINS; ENDOTOXEMIA; ENDOTOXINS; EXPRESSED SEQUENCE TAGS; GENE DELETION; HOMOZYGOTE; HUMANS; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; POINT MUTATION; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

EID: 0345561540     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.4.615     Document Type: Article

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