Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 5, 2000, Pages 2163-2167

  Poltorak, A ^a   Ricciardi Castagnoli, P ^b   Citterio, S ^b   Beutler, B ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b Dept of Biotech and Bioscience ^*  (Italy)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

C3H HeJ; Endotoxin; Macrophage; Specificity

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; ENDOTOXIN; LIPID A; MEMBRANE RECEPTOR; MESSENGER RNA; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETIC COMPLEMENTATION; GRAM NEGATIVE INFECTION; MACROPHAGE; MOUSE; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPECIES DIFFERENCE;

ANIMALS; BIOLOGICAL MARKERS; CELLS, CULTURED; DROSOPHILA PROTEINS; GENETIC COMPLEMENTATION TEST; HUMANS; LIPID A; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; RECEPTORS, CELL SURFACE; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA; NEGIBACTERIA;

EID: 0034007076     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.040565397     Document Type: Article

References (36)

1. Munford, R. S. & Hall, C. L. (1986) Science 234, 203-205.
2. Kanegasaki, S., Kojima, Y., Matsuura, M., Homma, J. Y., Yamamoto, A., Kumazawa, Y., Tanamoto, K., Yasuda, T., Tsumita, T. & Imoto, M. (1984) Eur. J. Biochem. 143, 237-242.
3. Galanos, C., Lehmann, V., Luderitz, O., Rietschel, E. T., Westphal, O., Brade, H., Brade, L., Freudenberg, M. A., Hansen-Hagge, T. & Luderitz, T. (1984) Eur. J. Biochem. 140, 221-227.
4. Birkland, T. P., Cornwell, R. D., Golenbock, D. T. & Proctor, R. A. (1990) Adv. Exp. Med. Biol. 256, 399-402.
5. Dal Nogare, A. R. & Yarbrough, W. C., Jr. (1990) J. Immunol. 144, 1404-1410.
6. Golenbock, D. T., Hampton, R. Y., Qureshi, N., Takayama, K. & Raetz, C. R. (1991) J. Biol. Chem. 266, 19490-19498.
7. Pohlman, T. H., Munford, R. S. & Harlan, J. M. (1987) J. Exp. Med. 165, 1393-1402.
8. Loppnow, H., Brade, H., Durrbaum, I., Dinarello, C. A., Kusumoto, S., Rietschel, E. T. & Flad, H. D. (1989) J. Immunol. 142, 3229-3238.
9. Wang, M. H., Flad, H. D., Feist, W., Brade, H., Kusumoto, S., Rietschel, E. T. & Ulmer, A. J. (1991) Infect. Immunol. 59, 4655-4664.
10. Wright, S. D., Ramos, R. A., Tobias, P. S., Ulevitch, R. J. & Mathison, J. C. (1990) Science 249, 1431-1433.
11. Kitchens, R. L., Ulevitch, R. J. & Munford, R. S. (1992) J. Exp. Med. 176, 485-494.
12. Kitchens, R. L. & Munford, R. S. (1995) J. Biol. Chem. 270, 9904-9910.
13. Delude, R. L., Savedra, R., Zhao, H. L., Thieringer, R., Yamamoto, S., Fenton, M. J. & Golenbock, D. T. (1995) Proc. Natl. Acad. Sci. USA 92, 9288-9292.
14. Poltorak, A., Smirnova, I., He, X. L., Liu, M. Y., Van Huffel, C., McNally, O., Birdwell, D., Alejos, E., Silva, M., Du, X., et al. (1998) Blood Cells Mol. Dis. 24, 340-355.
15. Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Van Huffel, C., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) Science 282, 2085-2088.
16. Michalek, S. M., Moore, R. N., McGhee, J. R., Rosenstreich, D. L. & Mergenhagen, S. E. (1980) J. Infect. Dis. 141, 55-63.
17. Freudenberg, M. A., Keppler, D. & Galanos, C. (1986) Infect. Immunol. 51, 891-895.
18. Mannel, D. N., Moore, R. N. & Mergenhagen, S. E. (1980) Infect. Immunol. 30, 523-530.
19. Beutler, B., Milsark, I. W. & Cerami, A. (1985) Science 229, 869-871.
20. Lutz, M. B., Granucci, F., Winzler, C., Marconi, G., Paglia, P., Foti, M., Assmann, C. U., Cairns, L., Rescigno, M. & Ricciardi-Castagnoli, P. (1994) J. Immunol. Methods 174, 269-279.
21. Pirami, L., Stockinger, B., Corradin, S. B., Sironi, M., Sassano, M., Valsasnini, P., Righi, M. & Ricciardi-Castagnoli, P. (1991) Proc. Natl. Acad. Sci. USA 88, 7543-7547.
22. Righi, M., Mori, L., DeLibero, G., Sironi, M., Biondi, A., Mantovani, A., Donini, S. D. & Ricciardi-Castagnoli, P. (1989) Eur. J. Immunol. 19, 1443-1448.
23. Righi, M., Pierani, A., Boglia, A., De, L. G., Mori, L., Marini, V. & Ricciardi-Castagnoli, P. (1989) Oncogene 4, 223-230.
24. Grignani, F., Kinsella, T., Mencarelli, A., Valtieri, M., Riganelli, D., Lanfrancone, L., Peschle, C., Nolan, G. P. & Pelicci, P. G. (1998) Cancer Res. 58, 14-19.
25. Cseh, K. & Beutler, B. (1989) J. Biol. Chem. 264, 16256-16260.
26. Du, X., Poltorak, A., Silva, M. & Beutler, B. (1999) Blood Cells Mol. Dis. 25, 328-338.
27. Favaloro, J., Treisman, R. & Kamen, R. (1980) Methods Enzymol. 65, 718.
28. Luderitz, T., Brandenburg, K., Seydel, U., Roth, A., Galanos, C. & Rietschel, E. T. (1989) Eur. J. Biochem. 179, 11-16.
29. Mukerjee, P., Kastowsky, M., Obst, S. & Takayama, K. (1999) in Lipopolysaccharide Preparations in Aqueous Media: Implications for Solution versus Suspension, eds. Brade, H., Opal, S. M., Vogel, S. N. & Morrison, D. C. (Dekker, New York), Vol. 12, pp. 221-228.
30. O'Brien, A. D., Rosenstreich, D. L., Scher, I., Campbell, G. H., MacDermott, R. P. & Formal, S. B. (1980) J. Immunol. 124, 20-24.
31. Rosenstreich, D. L., Weinblatt, A. C. & O'Brien, A. D. (1982) CRC Crit. Rev. Immunol. 3, 263-330.
32. Yu, B., Hailman, E. & Wright, SD (1997) J. Clin. Invest. 99, 315-324.
33. Schromm, A. B., Brandenburg, K., Rietschel, E. T., Flad, H. D., Carroll, S. F. & Seydel, U. (1996) FEBS Lett. 399, 267-271.
34. Yu, B. & Wright, S. D. (1996) J. Biol. Chem. 271, 4100-4105.
35. Hailman, E., Lichenstein, H. S., Wurfel, M. M., Miller, D. S., Johnson, D. A., Kelley, M., Busse, L. A., Zukowski, M. M. & Wright, S. D. (1994) J. Exp. Med. 179, 269-277.
36. Kirkland, T. N., Virca, G. D., Kuus-Reichel, T., Multer, F. K., Kim, S. Y., Ulevitch, R. J. & Tobias, P. S. (1990) J. Biol. Chem. 265, 9520-9525