Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. Coli

Nature

Volumn 416, Issue 6881, 2002, Pages 644-648

  Rämet, Mika ^a,b   Manfruelli, Pascal ^a,b   Pearson, Alan ^a   Mathey Prevot, Bernard ^b   Ezekowitz, R Alan B ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOSYNTHESIS; CELLS; ESCHERICHIA COLI; MUTAGENESIS; PHYSIOLOGICAL MODELS; RNA;

FUNCTIONAL GENOMIC ANALYSIS;

IMMUNOLOGY;

ACTIN; CELL SURFACE RECEPTOR; DOUBLE STRANDED RNA; GENE PRODUCT; PEPTIDOGLYCAN;

IMMUNITY;

ARTICLE; BACTERIAL IMMUNITY; BLOOD CELL; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOSKELETON; DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; GENOME ANALYSIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMORAL IMMUNITY; MACROPHAGE; MICROORGANISM DETECTION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL;

ACTINS; ANIMALS; ANTI-BACTERIAL AGENTS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EPISTASIS, GENETIC; ESCHERICHIA COLI; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENES, INSECT; GENES, REPORTER; GENOMICS; HEMOCYTES; MACROPHAGES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHAGOCYTOSIS; RNA, DOUBLE-STRANDED; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; STAPHYLOCOCCUS AUREUS; SURVIVAL RATE;

BACTERIA (MICROORGANISMS); DROSOPHILA MELANOGASTER; ESCHERICHIA COLI; HEXAPODA; INSECTA; MAMMALIA; MELANOGASTER; NEGIBACTERIA; POSIBACTERIA;

EID: 0037061482     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature735     Document Type: Article

References (31)

1. Properties of the larval hemocytes of Drosophila melanogaster
2. Requirement for Croquemort in phagocytosis of apoptotic cells in Drosophila
3. Mechanisms of phagocytosis in macrophages
4. The phagosome proteome: Insight into phagosome functions
5. Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria
6. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
7. Expression cloning of dSR-CI, a class C macrophage-specific scavenger receptor from Drosophila melanogaster
8. Flow cytometric assay for combined measurement of phagocytosis and intracellular killing of Candida albicans
9. Three ways to make a vesicle
10. Indirect role for COPI in the completion of FCgamma receptor-mediated phagocytosis
11. Clathrin-coated pit-associated proteins are required for alveolar macrophage phagocytosis
12. Specification of Drosophila hematopoietic lineage by conserved transcription factors
13. A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila
14. Mice homozygous for a truncated form of CREB-binding protein exhibit defects in hematopoiesis and vasculo-angiogenesis
15. A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene
16. A short stop is allelic to kakapo, and encodes rod-like cytoskeletal-associated proteins required for axon extension
17. LOLA has the properties of a master regulator of axon-target interaction for SNb motor axons of Drosophila
18. Drosophila Abelson interacting protein (dAbi) is a positive regulator of Abelson tyrosine kinase activity
19. The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
20. A family of Peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster
21. A Peptidoglycan recognition protein in innate immunity conserved from insects to humans
22. A pattern recognition protein for peptidoglycan. Cloning the cDNA and the gene of the silkworm, Bombyx mori
23. Mammalian Peptidoglycan recognition protein binds peptidoglycan with high affinity, is expressed in neutrophils, and inhibits bacterial growth
24. Peptidoglycan recognition proteins: A novel family of four human innate immunity pattern recognition molecules
25. Drosophila Toll is activated by Gram-positive bacteria through a circulating Peptidoglycan recognition protein
26. Toll-related receptors and the control of antimicrobial peptide expression in Drosophila
27. LPS-induced immune response in Drosophila
28. Dual-tagging gene trap of novel genes in Drosophila melanogaster
29. Signaling mechanisms in the antibacterial host defense of Drosophila
30. The Drosophila caspase Dredd is required to resist gram-negative bacterial infection
31. A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF