Mutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-κB-dependent innate immune responses

Genes and Development

Volumn 15, Issue 15, 2001, Pages 1900-1912

  Vidai, Sheila ^a   Khush, Ranjiv S ^a   Leulier, François ^a   Tzou, Phoebe ^a   Nakamura, Makoto ^b   Lemaitre, Bruno ^a  

^a CNRS   (France)

^b NATIONAL INSTITUTE FOR BASIC BIOLOGY   (Japan)

Author keywords

Antimicrobial peptide; Caspase; Innate immunity; Rel NF B; TAK1; Toll

Indexed keywords

CASPASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; MUTANT PROTEIN; PEPTIDE; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR REL; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; DROSOPHILA; ENZYME ACTIVITY; EVOLUTION; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC EPISTASIS; HOST RESISTANCE; IMMUNE RESPONSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROCESSING; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSGENE;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTI-BACTERIAL AGENTS; BETA-GALACTOSIDASE; CONSENSUS SEQUENCE; CONSERVED SEQUENCE; CROSSES, GENETIC; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ETHYL METHANESULFONATE; FEMALE; FERTILITY; GRAM-NEGATIVE BACTERIA; GREEN FLUORESCENT PROTEINS; INSECT PROTEINS; LUMINESCENT PROTEINS; MALE; MAMMALS; MAP KINASE KINASE KINASES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NF-KAPPA B; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-REL; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS); HEXAPODA; MAMMALIA; NEGIBACTERIA;

EID: 0035423794     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.203301     Document Type: Article

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