Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

Nature Medicine

Volumn 8, Issue 8, 2002, Pages 878-884

  Alexopoulou, Lena ^a   Thomas, Venetta ^a   Schnare, Markus ^a   Lobet, Yves ^b   Anguita, Juan ^c   Schoen, Robert T ^a   Medzhitov, Ruslan ^a   Fikrig, Erol ^a   Flavell, Richard A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE BIOLOGICALS   (Belgium)

^c UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; INTERLEUKIN 6; LIPOPROTEIN; LYME DISEASE VACCINE; OUTER SURFACE PROTEIN A; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ANTIGEN RECOGNITION; ARTICLE; BORRELIA BURGDORFERI; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VACCINATION;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, SURFACE; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; BORRELIA BURGDORFERI; CELL SEPARATION; CELLS, CULTURED; DROSOPHILA PROTEINS; HUMANS; INTERLEUKINS; LIPOPROTEINS; LYME DISEASE VACCINES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 1; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); BORRELIA; BORRELIA BURGDORFERI;

EID: 0036344106     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm732     Document Type: Article

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