-
1
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-I and IL-18-mediated function
-
Adachi, O., T. Kawai, K. Takeda, M. Matsumoto, H. Tsutsui, M. Sakagami, K. Nakanishi, and S. Akira. 1998. Targeted disruption of the MyD88 gene results in loss of IL-I and IL-18-mediated function. Immunity 9: 143-150.
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
Matsumoto, M.4
Tsutsui, H.5
Sakagami, M.6
Nakanishi, K.7
Akira, S.8
-
2
-
-
0030714605
-
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic cell function
-
Anderson, D.M., E. Maraskovsky, W.L. Billingley, W.C. Dougall, M.E. Tometsko, E.R. Roux, M.C. Teepe, R.F. DuBose, D. Cosman and L. Galibert. 1997. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic cell function. Nature 390: 175-179.
-
(1997)
Nature
, vol.390
, pp. 175-179
-
-
Anderson, D.M.1
Maraskovsky, E.2
Billingley, W.L.3
Dougall, W.C.4
Tometsko, M.E.5
Roux, E.R.6
Teepe, M.C.7
DuBose, R.F.8
Cosman, D.9
Galibert, L.10
-
3
-
-
0032530455
-
Tumor necrosis factor receptor-associated factors (TRAFs) - A family of adapter proteins that regulates life and death
-
Arch, R.H., R.W. Gedrich, and C.B. Thompson. 1998. Tumor necrosis factor receptor-associated factors (TRAFs) - a family of adapter proteins that regulates life and death. Genes & Dev. 12: 2821-2830.
-
(1998)
Genes & Dev.
, vol.12
, pp. 2821-2830
-
-
Arch, R.H.1
Gedrich, R.W.2
Thompson, C.B.3
-
4
-
-
0028201730
-
The CD40 antigen and its ligand
-
Banchereau, J., F. Bazan, F. Blanchard, J.P. Briere, C.Galizzi, C. van Kooten, Y.L. Liu, F. Rousset, and S. Saeland. 1994. The CD40 antigen and its ligand. Annu. Rev. Immunol. 12: 881-922.
-
(1994)
Annu. Rev. Immunol.
, vol.12
, pp. 881-922
-
-
Banchereau, J.1
Bazan, F.2
Blanchard, F.3
Briere, J.P.4
Galizzi, C.5
Van Kooten, C.6
Liu, Y.L.7
Rousset, F.8
Saeland, S.9
-
5
-
-
0002588171
-
Biology of the osteoclast
-
(ed. M. Noda), Springer Publishing, New York, NY
-
Baron, R., J.-H. Revesloot, L. Neff, M. Chakraborty, A. Chatterjee, A. Lomri, and W. Home. 1993. Biology of the osteoclast. In Cellular and molecular biology of bone (ed. M. Noda), pp. 445-495. Springer Publishing, New York, NY.
-
(1993)
Cellular and Molecular Biology of Bone
, pp. 445-495
-
-
Baron, R.1
Revesloot, J.-H.2
Neff, L.3
Chakraborty, M.4
Chatterjee, A.5
Lomri, A.6
Home, W.7
-
6
-
-
0026612467
-
Requirement of pp60c-src expression for osteoclasts to form ruffled borders and to resorb bone in mice
-
Boyce, B., T. Yoneda, C. Lowe, P. Soriano, and G. Mundy. 1992. Requirement of pp60c-src expression for osteoclasts to form ruffled borders and to resorb bone in mice. J. Clin. Invest. 90: 1622-1627.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 1622-1627
-
-
Boyce, B.1
Yoneda, T.2
Lowe, C.3
Soriano, P.4
Mundy, G.5
-
7
-
-
0029865142
-
IRAK: A kinase associated with the interleukin-1 receptor
-
Cao, Z., W. Henzel, and X. Gao. 1996a. IRAK: A kinase associated with the interleukin-1 receptor. Science 271:1128-1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.2
Gao, X.3
-
8
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao, Z., J. Xiong, M. Takeuchi, T. Kurama, and D.V. Goeddel. 1996b. TRAF6 is a signal transducer for interleukin-1. Nature 383: 443-446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
Kurama, T.4
Goeddel, D.V.5
-
9
-
-
0028936733
-
Involvement of CRAF1, a relative of TRAF, in CD40 signaling
-
Cheng, G., A.M. Cleary, Z.S. Ye, D.I. Hong, S. Lederman, and D. Baltimore. 1995. Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science 267: 1494-1498.
-
(1995)
Science
, vol.267
, pp. 1494-1498
-
-
Cheng, G.1
Cleary, A.M.2
Ye, Z.S.3
Hong, D.I.4
Lederman, S.5
Baltimore, D.6
-
10
-
-
0032493737
-
Characterization of the intracellular domain of receptor activator of NF-κB (RANK)
-
Darnay, B.C., V. Haridas, J. Ni, P.A. Moore, and B.B. Aggarwal. 1998. Characterization of the intracellular domain of receptor activator of NF-κB (RANK). J. Biol. Chem. 273:20551-20555.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 20551-20555
-
-
Darnay, B.C.1
Haridas, V.2
Ni, J.3
Moore, P.A.4
Aggarwal, B.B.5
-
11
-
-
0029979369
-
Biologic basis for interleukin-1 in disease
-
Dinarello, C.A. 1996. Biologic basis for interleukin-1 in disease. Blood 87: 2095-2147.
-
(1996)
Blood
, vol.87
, pp. 2095-2147
-
-
Dinarello, C.A.1
-
12
-
-
0031776896
-
LPS-binding proteins and receptors
-
Fenton, M.J. and D.T. Golenbock. 1998. LPS-binding proteins and receptors, J. Leuk. Biol. 64: 25-32.
-
(1998)
J. Leuk. Biol.
, vol.64
, pp. 25-32
-
-
Fenton, M.J.1
Golenbock, D.T.2
-
13
-
-
15444357762
-
Requirement for NF-κB in osteoclast and B-cell development
-
Franzoso, G., L. Carlson, L. Xing, L. Poljak, E.W. Shores, K.D. Brown, A. Leonardi, T. Tran, B.F. Boyce, and U. Siebenlist. 1997. Requirement for NF-κB in osteoclast and B-cell development. Genes & Dev. 11: 3482-3496.
-
(1997)
Genes & Dev.
, vol.11
, pp. 3482-3496
-
-
Franzoso, G.1
Carlson, L.2
Xing, L.3
Poljak, L.4
Shores, E.W.5
Brown, K.D.6
Leonardi, A.7
Tran, T.8
Boyce, B.F.9
Siebenlist, U.10
-
14
-
-
0032494113
-
TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts
-
Fuller, K., B. Wong, S. Fox, Y. Choi, and T.J. Chambers. 1998. TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. J. Exp. Med. 188: 997-1001.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 997-1001
-
-
Fuller, K.1
Wong, B.2
Fox, S.3
Choi, Y.4
Chambers, T.J.5
-
15
-
-
0032545465
-
The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-κB, a member of the TNFR superfamily
-
Galibert, L., M.E. Tometsko, D.M. Anderson, D. Cosman, and W.C. Dougall. 1998. The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-κB, a member of the TNFR superfamily. J. Biol. Chem. 273: 34120-34127.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34120-34127
-
-
Galibert, L.1
Tometsko, M.E.2
Anderson, D.M.3
Cosman, D.4
Dougall, W.C.5
-
16
-
-
0025774776
-
Drosophila toll and IL-1 receptor
-
Gay, N.J. and F.J. Keith 1991. Drosophila Toll and IL-1 receptor. Nature 351: 355-356.
-
(1991)
Nature
, vol.351
, pp. 355-356
-
-
Gay, N.J.1
Keith, F.J.2
-
17
-
-
0031252311
-
Phenotypic and functional characterization of mice that lack the type 1 receptor for IL-1
-
Glaccum, M.B., K.L. Stocking, K. Charrier, J.L. Smith, C.R. Willis, C. Maliszewski, D.J. Livingston, J.J. Peschon, and P.J. Morrissey. 1997. Phenotypic and functional characterization of mice that lack the type 1 receptor for IL-1. J. Immunol. 159: 3364-3371.
-
(1997)
J. Immunol.
, vol.159
, pp. 3364-3371
-
-
Glaccum, M.B.1
Stocking, K.L.2
Charrier, K.3
Smith, J.L.4
Willis, C.R.5
Maliszewski, C.6
Livingston, D.J.7
Peschon, J.J.8
Morrissey, P.J.9
-
18
-
-
0020448709
-
Analysis of nitrate, nitrite, and [15-N] nitrate in biological fluids
-
Green, L.C., D.A. Wagner, J. Glogowski, P.L. Skipper, J.S. Wishnok, and S.R. Tannenbaum. 1982. Analysis of nitrate, nitrite, and [15-N] nitrate in biological fluids. Ann. Biochem. 126: 131-138.
-
(1982)
Ann. Biochem.
, vol.126
, pp. 131-138
-
-
Green, L.C.1
Wagner, D.A.2
Glogowski, J.3
Skipper, P.L.4
Wishnok, J.S.5
Tannenbaum, S.R.6
-
19
-
-
0028173214
-
c-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling
-
Grigoriadis, A.E., Z.Q. Wang, M.G. Cecchini, W. Hofstetter, R. Felix, H.A. Fleisch, and E.F. Wagner. 1994. c-Fos: A key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science 266:443-448.
-
(1994)
Science
, vol.266
, pp. 443-448
-
-
Grigoriadis, A.E.1
Wang, Z.Q.2
Cecchini, M.G.3
Hofstetter, W.4
Felix, R.5
Fleisch, H.A.6
Wagner, E.F.7
-
20
-
-
0030920262
-
ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5
-
Hsu, H., I. Solovyev, A. Colombero, R. Elliott, M. Kelley, and W.J. Boyle. 1997. ATAR, a novel tumor necrosis factor receptor family member, signals through TRAF2 and TRAF5. J. Biol. Chem. 272: 13471-13474.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13471-13474
-
-
Hsu, H.1
Solovyev, I.2
Colombero, A.3
Elliott, R.4
Kelley, M.5
Boyle, W.J.6
-
21
-
-
13044316551
-
Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand
-
in press
-
Hsu, H., D.L. Lacey, C.R. Dunstan, I. Solovyev, A. Colombero, E. Timms, H.-L. Tan, G. Elliott, M.J. Kelley, I. Sarosi, L. Wang, X.-Z. Xia, R. Elliott, L. Chiu, T. Black, S. Scully, C. Capparelli, S. Morony, G. Shimamoto, M.B. Bass, and W.J. Boyle. 1999. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc. Natl. Acad. Sci 99: (in press).
-
(1999)
Proc. Natl. Acad. Sci
, vol.99
-
-
Hsu, H.1
Lacey, D.L.2
Dunstan, C.R.3
Solovyev, I.4
Colombero, A.5
Timms, E.6
Tan, H.-L.7
Elliott, G.8
Kelley, M.J.9
Sarosi, I.10
Wang, L.11
Xia, X.-Z.12
Elliott, R.13
Chiu, L.14
Black, T.15
Scully, S.16
Capparelli, C.17
Morony, S.18
Shimamoto, G.19
Bass, M.B.20
Boyle, W.J.21
more..
-
22
-
-
0030662372
-
Recruitment of IRAK to the interleukin-1 receptor complex requires interleukin-1 receptor accessory protein. Proc
-
Huang, J., X. Gao, S. Li, and Z. Cao. 1997. Recruitment of IRAK to the interleukin-1 receptor complex requires interleukin-1 receptor accessory protein. Proc. Natl. Acad. Sci. 94: 12829-12832.
-
(1997)
Natl. Acad. Sci.
, vol.94
, pp. 12829-12832
-
-
Huang, J.1
Gao, X.2
Li, S.3
Cao, Z.4
-
23
-
-
0030734791
-
Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts
-
Insogna, K.L., M. Sahni, A.B. Grey, S. Tanaka, W.C. Horne, L. Neff, M. Mitnick, J.B. Levy, and R. Baron. 1997. Colony-stimulating factor-1 induces cytoskeletal reorganization and c-src-dependent tyrosine phosphorylation of selected cellular proteins in rodent osteoclasts. J. Clin. Invest. 100: 2476-2485.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2476-2485
-
-
Insogna, K.L.1
Sahni, M.2
Grey, A.B.3
Tanaka, S.4
Horne, W.C.5
Neff, L.6
Mitnick, M.7
Levy, J.B.8
Baron, R.9
-
24
-
-
10544243364
-
Identification of TRAF6, a novel tumor-necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region
-
Ishida, T., S. Mizushima, S. Azuma, N. Kobayashi, T. Tojo, K. Suzuki, S. Aizawa, T. Watanabe, G. Mosialos, E. Kieff, T. Yamamoto, and J. Inoue. 1996a. Identification of TRAF6, a novel tumor-necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region. J. Biol. Chem. 271: 28745-28748.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28745-28748
-
-
Ishida, T.1
Mizushima, S.2
Azuma, S.3
Kobayashi, N.4
Tojo, T.5
Suzuki, K.6
Aizawa, S.7
Watanabe, T.8
Mosialos, G.9
Kieff, E.10
Yamamoto, T.11
Inoue, J.12
-
25
-
-
0029847814
-
TRAF5, a novel tumor necrosis factor receptor-associated factor protein, mediates CD40 signaling
-
Ishida, T.K., T. Tojo, T. Aoki, N. Kobayashi, T. Ohishi, T. Watanabe, T. Yamamoto, and J. Inoue. 1996b. TRAF5, a novel tumor necrosis factor receptor-associated factor protein, mediates CD40 signaling. Proc. Natl. Acad. Sci. 93: 9437-9442.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 9437-9442
-
-
Ishida, T.K.1
Tojo, T.2
Aoki, T.3
Kobayashi, N.4
Ohishi, T.5
Watanabe, T.6
Yamamoto, T.7
Inoue, J.8
-
26
-
-
0028447437
-
The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal centre formation
-
Kawabe, T., T. Naka, K. Yoshida, T. Tanaka, H. Fujiwara, S. Suematsu, N. Yoshida, T. Kishimoto, and H. Kikutani. 1994. The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal centre formation. Immunity 1: 167-178.
-
(1994)
Immunity
, vol.1
, pp. 167-178
-
-
Kawabe, T.1
Naka, T.2
Yoshida, K.3
Tanaka, T.4
Fujiwara, H.5
Suematsu, S.6
Yoshida, N.7
Kishimoto, T.8
Kikutani, H.9
-
27
-
-
0031774181
-
Human Toll-like receptor 2 confers responsiveness to bacterial LPS
-
Kirschning, C.J., H. Wesche, T.M. Ayres, and M. Rothe. 1998. Human Toll-like receptor 2 confers responsiveness to bacterial LPS. J. Exp. Med. 188: 2091-2097.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 2091-2097
-
-
Kirschning, C.J.1
Wesche, H.2
Ayres, T.M.3
Rothe, M.4
-
28
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, T cell activation, and lymph node organogenesis
-
Kong, Y.-Y., H. Yoshida, I. Sarosi, H.-L. Tan, E. Timms, C. Capparelli, S. Morony, G. Van, C.R. Dunstan, D.L. Lacey, T.W. Mak, W.J. Boyle, and J.M. Penninger. 1999. OPGL is a key regulator of osteoclastogenesis, T cell activation, and lymph node organogenesis. Nature 397: 315-323.
-
(1999)
Nature
, vol.397
, pp. 315-323
-
-
Kong, Y.-Y.1
Yoshida, H.2
Sarosi, I.3
Tan, H.-L.4
Timms, E.5
Capparelli, C.6
Morony, S.7
Van, G.8
Dunstan, C.R.9
Lacey, D.L.10
Mak, T.W.11
Boyle, W.J.12
Penninger, J.M.13
-
29
-
-
0031227868
-
Absence of IL-1 signaling and reduced inflammatory response in IL-1 type 1 receptor-deficient mice
-
Labow, M., D. Shuster, M. Zetterstrom, P. Nunes, R. Terry, E.B. Cullinan, T. Bartfai, C. Solorzano, L.L. Moldawer, R. Chizzonite, and K.W. McIntyre. 1997. Absence of IL-1 signaling and reduced inflammatory response in IL-1 type 1 receptor-deficient mice. J. Immunol. 159: 2452-2461.
-
(1997)
J. Immunol.
, vol.159
, pp. 2452-2461
-
-
Labow, M.1
Shuster, D.2
Zetterstrom, M.3
Nunes, P.4
Terry, R.5
Cullinan, E.B.6
Bartfai, T.7
Solorzano, C.8
Moldawer, L.L.9
Chizzonite, R.10
McIntyre, K.W.11
-
30
-
-
0032540319
-
Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation
-
Lacey, D.L., E. Timms, H.-L. Tan, M.J. Kelley, C.R. Dunstan, T. Burgess, R. Elliott, A. Colombero, G. Elliott, S. Scully, H. Hsu, J. Sullivan, N. Hawkins, E. Davy, C. Capparelli, A. Eli, Y.-X. Qian, S. Kaufman, I. Sarosi, V. Shalhoub, G. Senaldi, J. Guo, J. Delaney, and W.J. Boyle. 1998. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93: 165-176.
-
(1998)
Cell
, vol.93
, pp. 165-176
-
-
Lacey, D.L.1
Timms, E.2
Tan, H.-L.3
Kelley, M.J.4
Dunstan, C.R.5
Burgess, T.6
Elliott, R.7
Colombero, A.8
Elliott, G.9
Scully, S.10
Hsu, H.11
Sullivan, J.12
Hawkins, N.13
Davy, E.14
Capparelli, C.15
Eli, A.16
Qian, Y.-X.17
Kaufman, S.18
Sarosi, I.19
Shalhoub, V.20
Senaldi, G.21
Guo, J.22
Delaney, J.23
Boyle, W.J.24
more..
-
31
-
-
0030459512
-
IL-1 type 1 receptor mediates acute phase response to terpentine, but not lipopolysaccharide, in mice
-
Leon, L.R., C.A. Conn, M. Glaccum, and M.J. Kluger. 1996. IL-1 type 1 receptor mediates acute phase response to terpentine, but not lipopolysaccharide, in mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 40: R1668-R1675.
-
(1996)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.40
-
-
Leon, L.R.1
Conn, C.A.2
Glaccum, M.3
Kluger, M.J.4
-
32
-
-
0030298294
-
Dissection of TNF receptor 1 effector junctions: JNK activation is not linked to apoptosis while NF-KB activation prevents cell death
-
Liu, Z.-G., H. Hsu, D.V. Goeddel, and M. Karin. 1996. Dissection of TNF receptor 1 effector junctions: JNK activation is not linked to apoptosis while NF-KB activation prevents cell death. Cell 87: 565-576.
-
(1996)
Cell
, vol.87
, pp. 565-576
-
-
Liu, Z.-G.1
Hsu, H.2
Goeddel, D.V.3
Karin, M.4
-
33
-
-
0031017618
-
MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
-
Malinin, N., M.P. Boldin, A. Kovalenko, and D. Wallach. 1997. MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385: 540-544.
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.1
Boldin, M.P.2
Kovalenko, A.3
Wallach, D.4
-
34
-
-
0028281225
-
Distinct roles for CD4 and CD8 as co-receptors in T cell receptor signalling
-
Maroun, C.R. and M. Julius. 1994. Distinct roles for CD4 and CD8 as co-receptors in T cell receptor signalling. Em. J. Immunol. 24: 959-966.
-
(1994)
Em. J. Immunol.
, vol.24
, pp. 959-966
-
-
Maroun, C.R.1
Julius, M.2
-
35
-
-
0030920913
-
Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-κB and AP-1
-
Marsters, S.A., T.M. Ayres, M. Skubatch, C.L. Gray, M. Rothe, and A. Ashkenazi. 1997. Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-κB and AP-1. J. Biol. Chem. 272: 14029-14032.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14029-14032
-
-
Marsters, S.A.1
Ayres, T.M.2
Skubatch, M.3
Gray, C.L.4
Rothe, M.5
Ashkenazi, A.6
-
36
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov, R., P. Preston-Hurlburt, and C.A. Janeway. 1997. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388: 394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway, C.A.3
-
37
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signalling
-
Muzio, M., J. Ni, P. Feng, and V.M. Dixit. 1997. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signalling. Science 278: 1612-1615.
-
(1997)
Science
, vol.278
, pp. 1612-1615
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
38
-
-
0032526861
-
The human toll signaling pathway: Divergence of nuclear factor κ B and JNK/SAPK activation upstream of tumor necrosis receptor-associated factor 6 (TRAF6)
-
Muzio, M., G. Natoli, S. Saccani, M. Levrero, and A. Mantovani. 1998. The human Toll signaling pathway: Divergence of nuclear factor κ B and JNK/SAPK activation upstream of tumor necrosis receptor-associated factor 6 (TRAF6). J. Exp. Med. 187: 2097-2101.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2097-2101
-
-
Muzio, M.1
Natoli, G.2
Saccani, S.3
Levrero, M.4
Mantovani, A.5
-
39
-
-
15844428836
-
TRAF5, an activator of NF-kappa B and putative signal transducer for the lymphotoxin-beta receptor
-
Nakano, H., H. Oshima, W. Chung, L. Williams-Abbott, C.F. Ware, H. Yagita, and K. Okumura. 1996. TRAF5, an activator of NF-kappa B and putative signal transducer for the lymphotoxin-beta receptor, J. Biol. Chem. 271: 14661-14664.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 14661-14664
-
-
Nakano, H.1
Oshima, H.2
Chung, W.3
Williams-Abbott, L.4
Ware, C.F.5
Yagita, H.6
Okumura, K.7
-
40
-
-
0031801957
-
Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants
-
O'Neill, L.A.J. and C. Greene. 1998. Signal transduction pathways activated by the IL-1 receptor family: Ancient signaling machinery in mammals, insects, and plants. J. Leukoc. Biol. 63: 650-657.
-
(1998)
J. Leukoc. Biol.
, vol.63
, pp. 650-657
-
-
O'Neill, L.A.J.1
Greene, C.2
-
41
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/ 10ScCr mice: Mutations in TLR4 gene
-
Poltorak, A., X. He, I., Smirnova, M.-Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, M. Freudenberg, P. Ricciardi-Castagnoli, B. Layton, and B. Beutler. 1998. Defective LPS signaling in C3H/HeJ and C57BL/ 10ScCr mice: Mutations in TLR4 gene. Science 282: 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.-Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
42
-
-
0032566341
-
CD40-Tumor necrosis factor receptor associated factor (TRAF) interactions: Regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization
-
Pullen, S.S., H.G. Miller, D.S. Everdeen, T.T.A. Dang, J.J. Crute, and M.R. Kehry. 1998. CD40-Tumor necrosis factor receptor associated factor (TRAF) interactions: Regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization. Biochemistry 37: 11836-11845.
-
(1998)
Biochemistry
, vol.37
, pp. 11836-11845
-
-
Pullen, S.S.1
Miller, H.G.2
Everdeen, D.S.3
Dang, T.T.A.4
Crute, J.J.5
Kehry, M.R.6
-
43
-
-
0028124428
-
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor
-
Rothe, M., S.C. Wong, W.J. Henzel, and D.V. Goeddel. 1994. A novel family of putative signal transducers associated with the cytoplasmic domain of the 75kDa tumor necrosis factor receptor. Cell 78: 681-692.
-
(1994)
Cell
, vol.78
, pp. 681-692
-
-
Rothe, M.1
Wong, S.C.2
Henzel, W.J.3
Goeddel, D.V.4
-
44
-
-
0028978626
-
TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40
-
Rothe, M., V. Sarma, V.M. Dixit, and D.V. Goeddel. 1995. TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40. Science 269: 1424-1427.
-
(1995)
Science
, vol.269
, pp. 1424-1427
-
-
Rothe, M.1
Sarma, V.2
Dixit, V.M.3
Goeddel, D.V.4
-
45
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
Simonet, W.S., D.L. Lacey, C.R. Dunstan, M. Kelley, M.S. Chang, R. Luthy, H.Q. Nguyen, S. Wooden, L. Bennett, T. Boone, G. Shimamoto, M. DeRose, R. Elliott, A. Colombero, H.-L. Tan, G. Trail, J. Sullivan, E. Davy, N. Bucay, L. Renshaw-Gegg, T.M. Hughes, D. Hill, W. Pattison, P. Campbell, and W.J. Boyle. 1997. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell 89: 309-319.
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S.1
Lacey, D.L.2
Dunstan, C.R.3
Kelley, M.4
Chang, M.S.5
Luthy, R.6
Nguyen, H.Q.7
Wooden, S.8
Bennett, L.9
Boone, T.10
Shimamoto, G.11
DeRose, M.12
Elliott, R.13
Colombero, A.14
Tan, H.-L.15
Trail, G.16
Sullivan, J.17
Davy, E.18
Bucay, N.19
Renshaw-Gegg, L.20
Hughes, T.M.21
Hill, D.22
Pattison, W.23
Campbell, P.24
Boyle, W.J.25
more..
-
46
-
-
12644272789
-
Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of nuclear factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2
-
Song, H.Y., C.H. Regnier, C. Kirschning, D. Goeddel, and M. Rothe. 1997. Tumor necrosis factor (TNF)-mediated kinase cascades: Bifurcation of nuclear factor-κB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. Proc. Natl. Acad. Sci. 94: 9792-9796.
-
(1997)
Proc. Natl. Acad. Sci.
, vol.94
, pp. 9792-9796
-
-
Song, H.Y.1
Regnier, C.H.2
Kirschning, C.3
Goeddel, D.4
Rothe, M.5
-
47
-
-
0026023289
-
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
-
Soriano, P., C. Montgomery, R. Geske, and A. Bradley. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64: 693-702.
-
(1991)
Cell
, vol.64
, pp. 693-702
-
-
Soriano, P.1
Montgomery, C.2
Geske, R.3
Bradley, A.4
-
48
-
-
0029786304
-
Anatomy of TRAF2. Distinct domains for nuclear factor-kappa B activation and association with tumor necrosis signaling proteins
-
Takeuchi, M., M. Rothe, and D.V. Goeddel. 1996. Anatomy of TRAF2. Distinct domains for nuclear factor-kappa B activation and association with tumor necrosis signaling proteins. J. Biol. Chem. 271: 19935-19942.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19935-19942
-
-
Takeuchi, M.1
Rothe, M.2
Goeddel, D.V.3
-
49
-
-
0030933226
-
Osteopetrosis in mice lacking haematopoietic transcription factor PU.1
-
Tondravi, M.M., S.R. McKercher, K. Anderson, J.M. Erdmann, M. Quiroz, R. Maki, and S.L. Teitelbaum. 1997. Osteopetrosis in mice lacking haematopoietic transcription factor PU.1. Nature 386: 81-84.
-
(1997)
Nature
, vol.386
, pp. 81-84
-
-
Tondravi, M.M.1
McKercher, S.R.2
Anderson, K.3
Erdmann, J.M.4
Quiroz, M.5
Maki, R.6
Teitelbaum, S.L.7
-
50
-
-
0027070472
-
Bone and haematopoietic defects in mice lacking c-Fos
-
Wang, Z.-Q., C. Ovitt, A.E. Grigoriadis, U. Mohle-Steinlein, U. Ruther, and E.F. Wagner. 1992. Bone and haematopoietic defects in mice lacking c-Fos. Nature 360: 741-745.
-
(1992)
Nature
, vol.360
, pp. 741-745
-
-
Wang, Z.-Q.1
Ovitt, C.2
Grigoriadis, A.E.3
Mohle-Steinlein, U.4
Ruther, U.5
Wagner, E.F.6
-
51
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche, H., W. Henzel, W. Schillinglaw, S. Li, and Z. Cao. 1997a. MyD88: An adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7: 837-847.
-
(1997)
Immunity
, vol.7
, pp. 837-847
-
-
Wesche, H.1
Henzel, W.2
Schillinglaw, W.3
Li, S.4
Cao, Z.5
-
52
-
-
0030938198
-
The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases)
-
Wesche, H., C. Korherr, M. Kracht, W. Falk, K. Resch, and M.U. Martin. 1997b. The interleukin-1 receptor accessory protein (IL-1RAcP) is essential for IL-1-induced activation of interleukin-1 receptor-associated kinase (IRAK) and stress-activated protein kinases (SAP kinases). J. Biol. Chem. 272: 7727-7731.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7727-7731
-
-
Wesche, H.1
Korherr, C.2
Kracht, M.3
Falk, W.4
Resch, K.5
Martin, M.U.6
-
53
-
-
0032561198
-
The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor
-
Wong, B.R., R. Josien, S.Y. Lee, M. Vologodskaia, R.M. Steinman, and Y. Choi. 1998. The TRAF family of signal transducers mediates NF-κB activation by the TRANCE receptor. J. Biol. Chem. 273: 28355-28359.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28355-28359
-
-
Wong, B.R.1
Josien, R.2
Lee, S.Y.3
Vologodskaia, M.4
Steinman, R.M.5
Choi, Y.6
-
54
-
-
0028486131
-
Mice deficient for the CD40 ligand
-
Xu, J., T.M. Foy, J.D. Laman, E.A. Elliott, J.J. Dunn, T.J. Waldschmidt, J. Elsemore, R. Noelle, and R.A. Flavell. 1994. Mice deficient for the CD40 ligand. Immunity 1:423-431.
-
(1994)
Immunity
, vol.1
, pp. 423-431
-
-
Xu, J.1
Foy, T.M.2
Laman, J.D.3
Elliott, E.A.4
Dunn, J.J.5
Waldschmidt, T.J.6
Elsemore, J.7
Noelle, R.8
Flavell, R.A.9
-
55
-
-
0030292777
-
Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses
-
Xu, Y., G. Cheng, and D. Baltimore. 1996. Targeted disruption of TRAF3 leads to postnatal lethality and defective T-dependent immune responses. Immunity 5: 407-415.
-
(1996)
Immunity
, vol.5
, pp. 407-415
-
-
Xu, Y.1
Cheng, G.2
Baltimore, D.3
-
56
-
-
0032541661
-
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
-
Yang, R.-B., M.R. Mark, A. Gray, A. Huang, M.H. Xie, M. Zhang, A. Goddard, W.I. Wood, A.L. Gurney, and P.J. Godowski. 1998. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling. Nature 395: 284-288.
-
(1998)
Nature
, vol.395
, pp. 284-288
-
-
Yang, R.-B.1
Mark, M.R.2
Gray, A.3
Huang, A.4
Xie, M.H.5
Zhang, M.6
Goddard, A.7
Wood, W.I.8
Gurney, A.L.9
Godowski, P.J.10
-
57
-
-
0031463025
-
Early lethality, fuctional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice
-
Yeh, W.-C., A. Shahinian, D. Speiser, J. Kraunus, F. Billia, A. Wakeham, J.L. de la Pompa, D. Ferrick, B. Hum, N. Iscove, P. Ohashi, M. Rothe, D.V. Goeddel, and T.W. Mak. 1997. Early lethality, fuctional NF-κB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. Immunity 71: 715-725.
-
(1997)
Immunity
, vol.71
, pp. 715-725
-
-
Yeh, W.-C.1
Shahinian, A.2
Speiser, D.3
Kraunus, J.4
Billia, F.5
Wakeham, A.6
De La Pompa, J.L.7
Ferrick, D.8
Hum, B.9
Iscove, N.10
Ohashi, P.11
Rothe, M.12
Goeddel, D.V.13
Mak, T.W.14
-
58
-
-
0025332897
-
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene
-
Yoshida, H., S.-I. Hayashi, T. Kunisada, M. Ogawa, S. Nishikawa, H. Okamura, T. Sudo, L.D. Shultz, and S.-I. Nishikawa. 1990. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345: 442-443.
-
(1990)
Nature
, vol.345
, pp. 442-443
-
-
Yoshida, H.1
Hayashi, S.-I.2
Kunisada, T.3
Ogawa, M.4
Nishikawa, S.5
Okamura, H.6
Sudo, T.7
Shultz, L.D.8
Nishikawa, S.-I.9
-
59
-
-
0029157723
-
Resistance to fever induction and impaired acute phase response in interleukin-1β-deficient mice
-
Zheng, H., D. Fletcher, W. Kozak, M. Jiang, K.J. Hofmann, C.A. Conn, D. Soszynski, C. Grabiec, M.E. Trumbauer, and A. Shaw. 1995. Resistance to fever induction and impaired acute phase response in interleukin-1β-deficient mice. Immunity 3: 9-19.
-
(1995)
Immunity
, vol.3
, pp. 9-19
-
-
Zheng, H.1
Fletcher, D.2
Kozak, W.3
Jiang, M.4
Hofmann, K.J.5
Conn, C.A.6
Soszynski, D.7
Grabiec, C.8
Trumbauer, M.E.9
Shaw, A.10
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