Interleukin (IL)-1 receptor-associated kinase (IRAK) requirement for optimal induction of multiple IL-1 signaling pathways and IL-6 production

Journal of Experimental Medicine

Volumn 187, Issue 12, 1998, Pages 2073-2079

  Kanakaraj, Palanisamy ^a   Schafer, Peter H ^b   Cavender, Druie E ^b   Wu, Ying ^a   Ngo, Karen ^a   Grealish, Patrick F ^b   Wadsworth, Scott A ^b   Peterson, Per A ^b   Siekierka, John J ^b   Harris, Crafford A ^b   Fung Leung, Wai Ping ^a  

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

IL 1; IRAK; JNK; NF B; p38

Indexed keywords

GENE PRODUCT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA BINDING; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOBLOTTING; INFLAMMATION; INFLAMMATORY DISEASE; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RECEPTOR BINDING; SIGNAL TRANSDUCTION; SKIN FIBROBLAST;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; EMBRYO; FIBROBLASTS; INTERLEUKIN-1; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; INTERLEUKIN-6; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASES; RECEPTORS, INTERLEUKIN-1; SIGNAL TRANSDUCTION; SKIN; X CHROMOSOME;

EID: 0032526555     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.12.2073     Document Type: Article

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