-
1
-
-
84884412859
-
Usp16 contributes to somatic stem-cell defects in Down's syndrome
-
Adorno M, Sikandar S, Mitra SS, Kuo A, Nicolis di Robilant B, et al. 2013. Usp16 contributes to somatic stem-cell defects in Down's syndrome. Nature 501: 380-84
-
(2013)
Nature
, vol.501
, pp. 380-384
-
-
Adorno, M.1
Sikandar, S.2
Mitra, S.S.3
Kuo, A.4
Nicolis Di Robilant, B.5
-
2
-
-
85020747182
-
PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation
-
Almeida M, Pintacuda G, Masui O, Koseki Y, Gdula M, et al. 2017. PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. Science 356: 1081-84
-
(2017)
Science
, vol.356
, pp. 1081-1084
-
-
Almeida, M.1
Pintacuda, G.2
Masui, O.3
Koseki, Y.4
Gdula, M.5
-
3
-
-
84919497292
-
AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics
-
Antonioli M, Albiero F, Nazio F, Vescovo T, Perdomo AB, et al. 2014. AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamics. Dev. Cell 31: 734-46
-
(2014)
Dev. Cell
, vol.31
, pp. 734-746
-
-
Antonioli, M.1
Albiero, F.2
Nazio, F.3
Vescovo, T.4
Perdomo, A.B.5
-
4
-
-
77955109451
-
A bacterial E3 ubiquitin ligase IpaH9. 8 targets NEMO/IKK to dampen the host NF-B-mediated inflammatory response
-
Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M, Sasakawa C. 2010. A bacterial E3 ubiquitin ligase IpaH9. 8 targets NEMO/IKK to dampen the host NF-B-mediated inflammatory response. Nat. Cell Biol. 12: 66-73; Suppl. 1-9
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 66-73
-
-
Ashida, H.1
Kim, M.2
Schmidt-Supprian, M.3
Ma, A.4
Ogawa, M.5
Sasakawa, C.6
-
5
-
-
84964691977
-
ATXN7L3 and ENY2 coordinate activity of multiple H2B deubiquitinases important for cellular proliferation and tumor growth
-
Atanassov BS, Mohan RD, Lan X, Kuang X, Lu Y, et al. 2016. ATXN7L3 and ENY2 coordinate activity of multiple H2B deubiquitinases important for cellular proliferation and tumor growth. Mol. Cell 62: 558-71
-
(2016)
Mol. Cell
, vol.62
, pp. 558-571
-
-
Atanassov, B.S.1
Mohan, R.D.2
Lan, X.3
Kuang, X.4
Lu, Y.5
-
6
-
-
85030832225
-
Large-scale quantitative proteomics identifies the ubiquitin ligase Nedd4-1 as an essential regulator of liver regeneration
-
616-25e8
-
Bachofner M, Speicher T, Bogorad RL, Muzumdar S, Derrer CP, et al. 2017. Large-scale quantitative proteomics identifies the ubiquitin ligase Nedd4-1 as an essential regulator of liver regeneration. Dev. Cell 42: 616-25. e8
-
(2017)
Dev. Cell
, vol.42
-
-
Bachofner, M.1
Speicher, T.2
Bogorad, R.L.3
Muzumdar, S.4
Derrer, C.P.5
-
7
-
-
77957169824
-
Role of a ribosome-associated E3 ubiquitin ligase in protein quality control
-
Bengtson MH, JoazeiroCA. 2010. Role of a ribosome-associated E3 ubiquitin ligase in protein quality control. Nature 467: 470-73
-
(2010)
Nature
, vol.467
, pp. 470-473
-
-
Bengtson, M.H.1
Joazeiro, C.A.2
-
8
-
-
85048898762
-
Protein quality control of the endoplasmic reticulum and ubiquitinproteasome-triggered degradation of aberrant proteins: Yeast pioneers the path
-
Berner N, Reutter KR, Wolf DH. 2018. Protein quality control of the endoplasmic reticulum and ubiquitinproteasome-triggered degradation of aberrant proteins: Yeast pioneers the path. Annu. Rev. Biochem. 87: 751-82
-
(2018)
Annu. Rev. Biochem.
, vol.87
, pp. 751-782
-
-
Berner, N.1
Reutter, K.R.2
Wolf, D.H.3
-
9
-
-
85001889664
-
Phosphoribosylation of ubiquitin promotes serine ubiquitination and impairs conventional ubiquitination
-
1636-49e13
-
Bhogaraju S, Kalayil S, Liu Y, Bonn F, Colby T, et al. 2016. Phosphoribosylation of ubiquitin promotes serine ubiquitination and impairs conventional ubiquitination. Cell 167: 1636-49. e13
-
(2016)
Cell
, vol.167
-
-
Bhogaraju, S.1
Kalayil, S.2
Liu, Y.3
Bonn, F.4
Colby, T.5
-
10
-
-
84902127230
-
Variant PRC1 complex-dependentH2A ubiquitylation drives PRC2 recruitment and polycomb domain formation
-
Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, et al. 2014. Variant PRC1 complex-dependentH2A ubiquitylation drives PRC2 recruitment and polycomb domain formation. Cell 157: 1445-59
-
(2014)
Cell
, vol.157
, pp. 1445-1459
-
-
Blackledge, N.P.1
Farcas, A.M.2
Kondo, T.3
King, H.W.4
McGouran, J.F.5
-
11
-
-
85019969049
-
Ubiquitin-and ATP-dependent unfoldase activity of P97/VCPNPLOC4UFD1L is enhanced by a mutation that causes multisystem proteinopathy
-
Blythe EE, Olson KC, Chau V, Deshaies RJ. 2017. Ubiquitin-and ATP-dependent unfoldase activity of P97/VCPNPLOC4UFD1L is enhanced by a mutation that causes multisystem proteinopathy. PNAS 114: E4380-88
-
(2017)
PNAS
, vol.114
, pp. E4380-E4388
-
-
Blythe, E.E.1
Olson, K.C.2
Chau, V.3
Deshaies, R.J.4
-
12
-
-
85018732290
-
Molecular mechanism of substrate processing by theCdc48 ATPase complex
-
722-35e9
-
BodnarNO, RapoportTA. 2017. Molecular mechanism of substrate processing by theCdc48 ATPase complex. Cell 169: 722-35. e9
-
(2017)
Cell
, vol.169
-
-
Bodnar, N.O.1
Rapoport, T.A.2
-
13
-
-
84930646986
-
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5- end resection
-
Boersma V, Moatti N, Segura-Bayona S, PeuscherMH, van der Torre J, et al. 2015. MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5- end resection. Nature 521: 537-40
-
(2015)
Nature
, vol.521
, pp. 537-540
-
-
Boersma, V.1
Moatti, N.2
Segura-Bayona, S.3
Peuscher, M.H.4
Van Der Torre, J.5
-
14
-
-
78649292467
-
Ubiquitin binding to A20 ZnF4 is required for modulation of NF-B signaling
-
Bosanac I, Wertz IE, Pan B, Yu C, Kusam S, et al. 2010. Ubiquitin binding to A20 ZnF4 is required for modulation of NF-B signaling. Mol. Cell 40: 548-57
-
(2010)
Mol. Cell
, vol.40
, pp. 548-557
-
-
Bosanac, I.1
Wertz, I.E.2
Pan, B.3
Yu, C.4
Kusam, S.5
-
15
-
-
84871523350
-
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress
-
Brandman O, Stewart-Ornstein J, Wong D, Larson A, Williams CC, et al. 2012. A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress. Cell 151: 1042-54
-
(2012)
Cell
, vol.151
, pp. 1042-1054
-
-
Brandman, O.1
Stewart-Ornstein, J.2
Wong, D.3
Larson, A.4
Williams, C.C.5
-
16
-
-
0032531925
-
A novel site for ubiquitination: The Nterminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein
-
Breitschopf K, Bengal E, Ziv T, Admon A, Ciechanover A. 1998. A novel site for ubiquitination: The Nterminal residue, and not internal lysines of MyoD, is essential for conjugation and degradation of the protein. EMBO J. 17: 5964-73
-
(1998)
EMBO J.
, vol.17
, pp. 5964-5973
-
-
Breitschopf, K.1
Bengal, E.2
Ziv, T.3
Admon, A.4
Ciechanover, A.5
-
17
-
-
84895020019
-
A regulator of secretory vesicle size, Kelch-like protein 12, facilitates the secretion of apolipoprotein B100 and very-low-density lipoproteins-brief report
-
Butkinaree C, Guo L, Ramkhelawon B, Wanschel A, Brodsky JL, et al. 2014. A regulator of secretory vesicle size, Kelch-like protein 12, facilitates the secretion of apolipoprotein B100 and very-low-density lipoproteins-brief report. Arterioscler. Thromb. Vasc. Biol. 34: 251-54
-
(2014)
Arterioscler. Thromb. Vasc. Biol.
, vol.34
, pp. 251-254
-
-
Butkinaree, C.1
Guo, L.2
Ramkhelawon, B.3
Wanschel, A.4
Brodsky, J.L.5
-
18
-
-
21744433861
-
Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase
-
Cadwell K, Coscoy L. 2005. Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase. Science 309: 127-30
-
(2005)
Science
, vol.309
, pp. 127-130
-
-
Cadwell, K.1
Coscoy, L.2
-
19
-
-
29144487990
-
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing
-
Cao R, Tsukada Y, Zhang Y. 2005. Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol. Cell 20: 845-54
-
(2005)
Mol. Cell
, vol.20
, pp. 845-854
-
-
Cao, R.1
Tsukada, Y.2
Zhang, Y.3
-
20
-
-
0036830642
-
Role of histoneH3 lysine 27methylation in Polycomb-group silencing
-
Cao R, Wang L, Wang H, Xia L, Erdjument-Bromage H, et al. 2002. Role of histoneH3 lysine 27methylation in Polycomb-group silencing. Science 298: 1039-43
-
(2002)
Science
, vol.298
, pp. 1039-1043
-
-
Cao, R.1
Wang, L.2
Wang, H.3
Xia, L.4
Erdjument-Bromage, H.5
-
21
-
-
0024514688
-
A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
-
Chau V, Tobias JW, Bachmair A, Marriott D, Ecker DJ, et al. 1989. A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science 243: 1576-83
-
(1989)
Science
, vol.243
, pp. 1576-1583
-
-
Chau, V.1
Tobias, J.W.2
Bachmair, A.3
Marriott, D.4
Ecker, D.J.5
-
22
-
-
60549094028
-
A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration
-
Chu J, Hong NA, Masuda CA, Jenkins BV, Nelms KA, et al. 2009. A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. PNAS 106: 2097-103
-
(2009)
PNAS
, vol.106
, pp. 2097-2103
-
-
Chu, J.1
Hong, N.A.2
Masuda, C.A.3
Jenkins, B.V.4
Nelms, K.A.5
-
23
-
-
0035146685
-
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
-
Connell P, Ballinger CA, Jiang J, Wu Y, Thompson LJ, et al. 2001. The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins. Nat. Cell Biol. 3: 93-96
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 93-96
-
-
Connell, P.1
Ballinger, C.A.2
Jiang, J.3
Wu, Y.4
Thompson, L.J.5
-
24
-
-
84902333500
-
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment
-
Cooper S, Dienstbier M, Hassan R, Schermelleh L, Sharif J, et al. 2014. Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment. Cell Rep. 7: 1456-70
-
(2014)
Cell Rep.
, vol.7
, pp. 1456-1470
-
-
Cooper, S.1
Dienstbier, M.2
Hassan, R.3
Schermelleh, L.4
Sharif, J.5
-
25
-
-
84923167247
-
USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
-
CunninghamCN, Baughman JM, Phu L, Tea JS, YuC, et al. 2015. USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria. Nat. Cell Biol. 17: 160-69
-
(2015)
Nat. Cell Biol.
, vol.17
, pp. 160-169
-
-
Cunningham, C.N.1
Baughman, J.M.2
Phu, L.3
Tea, J.S.4
Yu, C.5
-
26
-
-
84981719187
-
The deubiquitinase OTULIN is an essential negative regulator of inflammation and autoimmunity
-
1215-30e20
-
Damgaard RB, Walker JA, Marco-Casanova P, Morgan NV, Titheradge HL, et al. 2016. The deubiquitinase OTULIN is an essential negative regulator of inflammation and autoimmunity. Cell 166: 1215-30. e20
-
(2016)
Cell
, vol.166
-
-
Damgaard, R.B.1
Walker, J.A.2
Marco-Casanova, P.3
Morgan, N.V.4
Titheradge, H.L.5
-
27
-
-
84994158199
-
Building a regulatory network with short linear sequence motifs: Lessons from the degrons of the anaphase-promoting complex
-
Davey NE, Morgan DO. 2016. Building a regulatory network with short linear sequence motifs: lessons from the degrons of the anaphase-promoting complex. Mol. Cell 64: 12-23
-
(2016)
Mol. Cell
, vol.64
, pp. 12-23
-
-
Davey, N.E.1
Morgan, D.O.2
-
28
-
-
84991404802
-
Shigella flexneri suppressesNF-B activation by inhibiting linear ubiquitin chain ligation
-
de Jong MF, Liu Z, Chen D, Alto NM. 2016. Shigella flexneri suppressesNF-B activation by inhibiting linear ubiquitin chain ligation. Nat. Microbiol. 1: 16084
-
(2016)
Nat. Microbiol.
, vol.1
, pp. 16084
-
-
De Jong, M.F.1
Liu, Z.2
Chen, D.3
Alto, N.M.4
-
29
-
-
0034644474
-
Activation of the IB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain
-
Deng L, Wang C, Spencer E, Yang L, Braun A, et al. 2000. Activation of the IB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Cell 103: 351-61
-
(2000)
Cell
, vol.103
, pp. 351-361
-
-
Deng, L.1
Wang, C.2
Spencer, E.3
Yang, L.4
Braun, A.5
-
31
-
-
84946405304
-
A prospective study on histone-H2AX and 53BP1 foci expression in rectal carcinoma patients: Correlation with radiation therapy-induced outcome
-
Djuzenova CS, ZimmermannM, Katzer A, Fiedler V, Distel LV, et al. 2015. A prospective study on histone-H2AX and 53BP1 foci expression in rectal carcinoma patients: correlation with radiation therapy-induced outcome. BMC Cancer 15: 856
-
(2015)
BMC Cancer
, vol.15
, pp. 856
-
-
Djuzenova, C.S.1
Zimmermann, M.2
Katzer, A.3
Fiedler, V.4
Distel, L.V.5
-
32
-
-
84942826638
-
Starvation-dependent regulation of Golgi quality control links theTORsignaling and vacuolar protein sorting pathways
-
Dobzinski N, Chuartzman SG, Kama R, Schuldiner M, Gerst JE. 2015. Starvation-dependent regulation of Golgi quality control links theTORsignaling and vacuolar protein sorting pathways. Cell Rep. 12: 1876-86
-
(2015)
Cell Rep.
, vol.12
, pp. 1876-1886
-
-
Dobzinski, N.1
Chuartzman, S.G.2
Kama, R.3
Schuldiner, M.4
Gerst, J.E.5
-
33
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C, MailandN, Bekker-Jensen S, Menard P, Larsen DH, et al. 2009. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 136: 435-46
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
-
34
-
-
84944893122
-
RFWD3-dependent ubiquitination of RPA regulates repair at stalled replication forks
-
Elia AE, Wang DC, Willis NA, Boardman AP, Hajdu I, et al. 2015. RFWD3-dependent ubiquitination of RPA regulates repair at stalled replication forks. Mol. Cell 60: 280-93
-
(2015)
Mol. Cell
, vol.60
, pp. 280-293
-
-
Elia, A.E.1
Wang, D.C.2
Willis, N.A.3
Boardman, A.P.4
Hajdu, I.5
-
35
-
-
84991672335
-
SPATA2 links CYLD to LUBAC, activates CYLD, and controls LUBAC signaling
-
Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, et al. 2016. SPATA2 links CYLD to LUBAC, activates CYLD, and controls LUBAC signaling. Mol. Cell 63: 990-1005
-
(2016)
Mol. Cell
, vol.63
, pp. 990-1005
-
-
Elliott, P.R.1
Leske, D.2
Hrdinka, M.3
Bagola, K.4
Fiil, B.K.5
-
36
-
-
84899911195
-
Molecular basis and regulation of OTULIN-LUBAC interaction
-
Elliott PR, Nielsen SV, Marco-Casanova P, Fiil BK, KeusekottenK, et al. 2014. Molecular basis and regulation of OTULIN-LUBAC interaction. Mol. Cell 54: 335-48
-
(2014)
Mol. Cell
, vol.54
, pp. 335-348
-
-
Elliott, P.R.1
Nielsen, S.V.2
Marco-Casanova, P.3
Fiil, B.K.4
Keusekotten, K.5
-
37
-
-
80054694510
-
Global identification ofmodular Cullin-RING ligase substrates
-
EmanueleMJ, Elia AE, Xu Q, Thoma CR, Izhar L, et al. 2011. Global identification ofmodular Cullin-RING ligase substrates. Cell 147: 459-74
-
(2011)
Cell
, vol.147
, pp. 459-474
-
-
Emanuele, M.J.1
Elia, A.E.2
Xu, Q.3
Thoma, C.R.4
Izhar, L.5
-
38
-
-
84965070534
-
Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling
-
Emmerich CH, Bakshi S, Kelsall IR, Ortiz-Guerrero J, Shpiro N, Cohen P. 2016. Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling. Biochem. Biophys. Res. Commun. 474: 452-61
-
(2016)
Biochem. Biophys. Res. Commun.
, vol.474
, pp. 452-461
-
-
Emmerich, C.H.1
Bakshi, S.2
Kelsall, I.R.3
Ortiz-Guerrero, J.4
Shpiro, N.5
Cohen, P.6
-
39
-
-
84884345970
-
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
-
Emmerich CH, Ordureau A, Strickson S, Arthur JS, Pedrioli PG, et al. 2013. Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains. PNAS 110: 15247-52
-
(2013)
PNAS
, vol.110
, pp. 15247-15252
-
-
Emmerich, C.H.1
Ordureau, A.2
Strickson, S.3
Arthur, J.S.4
Pedrioli, P.G.5
-
40
-
-
84974694623
-
Global analysis of host and bacterial ubiquitinome in response to Salmonella Typhimurium infection
-
Fiskin E, Bionda T, Dikic I, Behrends C. 2016. Global analysis of host and bacterial ubiquitinome in response to Salmonella Typhimurium infection. Mol. Cell 62: 967-81
-
(2016)
Mol. Cell
, vol.62
, pp. 967-981
-
-
Fiskin, E.1
Bionda, T.2
Dikic, I.3
Behrends, C.4
-
41
-
-
84879888213
-
53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark
-
Fradet-Turcotte A, Canny MD, Escribano-Diaz C, Orthwein A, Leung CC, et al. 2013. 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark. Nature 499: 50-54
-
(2013)
Nature
, vol.499
, pp. 50-54
-
-
Fradet-Turcotte, A.1
Canny, M.D.2
Escribano-Diaz, C.3
Orthwein, A.4
Leung, C.C.5
-
42
-
-
85028345991
-
ESCRT-dependent cargo sorting at multivesicular endosomes
-
Frankel EB, Audhya A. 2018. ESCRT-dependent cargo sorting at multivesicular endosomes. Semin. Cell Dev. Biol. 74: 4-10
-
(2018)
Semin. Cell Dev. Biol.
, vol.74
, pp. 4-10
-
-
Frankel, E.B.1
Audhya, A.2
-
43
-
-
84861968321
-
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation
-
Fuchs G, Shema E, Vesterman R, Kotler E, Wolchinsky Z, et al. 2012. RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Mol. Cell 46: 662-73
-
(2012)
Mol. Cell
, vol.46
, pp. 662-673
-
-
Fuchs, G.1
Shema, E.2
Vesterman, R.3
Kotler, E.4
Wolchinsky, Z.5
-
44
-
-
84863011309
-
PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes
-
Gao Z, Zhang J, Bonasio R, Strino F, Sawai A, et al. 2012. PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. Mol. Cell 45: 344-56
-
(2012)
Mol. Cell
, vol.45
, pp. 344-356
-
-
Gao, Z.1
Zhang, J.2
Bonasio, R.3
Strino, F.4
Sawai, A.5
-
45
-
-
17644396667
-
Degradation-mediated protein quality control in the nucleus
-
Gardner RG, Nelson ZW, Gottschling DE. 2005. Degradation-mediated protein quality control in the nucleus. Cell 120: 803-15
-
(2005)
Cell
, vol.120
, pp. 803-815
-
-
Gardner, R.G.1
Nelson, Z.W.2
Gottschling, D.E.3
-
46
-
-
84991670975
-
Mapping the landscape of a eukaryotic degronome
-
Geffen Y, Appleboim A, Gardner RG, Friedman N, Sadeh R, Ravid T. 2016. Mapping the landscape of a eukaryotic degronome. Mol. Cell 63: 1055-65
-
(2016)
Mol. Cell
, vol.63
, pp. 1055-1065
-
-
Geffen, Y.1
Appleboim, A.2
Gardner, R.G.3
Friedman, N.4
Sadeh, R.5
Ravid, T.6
-
47
-
-
85030661011
-
Mechanism and regulation of the Lys6-selective deubiquitinase USP30
-
Gersch M, Gladkova C, Schubert AF, Michel MA, Maslen S, Komander D. 2017. Mechanism and regulation of the Lys6-selective deubiquitinase USP30. Nat. Struct. Mol. Biol. 24: 920-30
-
(2017)
Nat. Struct. Mol. Biol.
, vol.24
, pp. 920-930
-
-
Gersch, M.1
Gladkova, C.2
Schubert, A.F.3
Michel, M.A.4
Maslen, S.5
Komander, D.6
-
48
-
-
33744906046
-
Genomic models of metastatic cancer: Functional analysis of death-from-cancer signature genes reveals aneuploid, anoikis-resistant, metastasis-enabling phenotype with altered cell cycle control and activated Polycomb Group (PcG) protein chromatin silencing pathway
-
Glinsky GV. 2006. Genomic models of metastatic cancer: functional analysis of death-from-cancer signature genes reveals aneuploid, anoikis-resistant, metastasis-enabling phenotype with altered cell cycle control and activated Polycomb Group (PcG) protein chromatin silencing pathway. Cell Cycle 5: 1208-16
-
(2006)
Cell Cycle
, vol.5
, pp. 1208-1216
-
-
Glinsky, G.V.1
-
50
-
-
85021823440
-
COPII-coated membranes function as transport carriers of intracellular procollagen i
-
Gorur A, YuanL, Kenny SJ, Baba S, XuK, SchekmanR. 2017. COPII-coated membranes function as transport carriers of intracellular procollagen I. J. Cell Biol. 216: 1745-59
-
(2017)
J. Cell Biol.
, vol.216
, pp. 1745-1759
-
-
Gorur, A.1
Yuan, L.2
Kenny, S.J.3
Baba, S.4
Xu, K.5
Schekman, R.6
-
51
-
-
84865232294
-
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes
-
Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, et al. 2012. TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes. Cell 150: 697-709
-
(2012)
Cell
, vol.150
, pp. 697-709
-
-
Gudjonsson, T.1
Altmeyer, M.2
Savic, V.3
Toledo, L.4
Dinant, C.5
-
54
-
-
75749101057
-
Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1
-
Heck JW, Cheung SK, Hampton RY. 2010. Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1. PNAS 107: 1106-11
-
(2010)
PNAS
, vol.107
, pp. 1106-1111
-
-
Heck, J.W.1
Cheung, S.K.2
Hampton, R.Y.3
-
55
-
-
79960637590
-
Protein targeting and degradation are coupled for elimination of mislocalized proteins
-
Hessa T, Sharma A, Mariappan M, Eshleman HD, Gutierrez E, Hegde RS. 2011. Protein targeting and degradation are coupled for elimination of mislocalized proteins. Nature 475: 394-97
-
(2011)
Nature
, vol.475
, pp. 394-397
-
-
Hessa, T.1
Sharma, A.2
Mariappan, M.3
Eshleman, H.D.4
Gutierrez, E.5
Hegde, R.S.6
-
56
-
-
84934448890
-
The unfolded protein response triggers site-specific regulatory ubiquitylation of 40S ribosomal proteins
-
Higgins R, Gendron JM, Rising L, Mak R, Webb K, et al. 2015. The unfolded protein response triggers site-specific regulatory ubiquitylation of 40S ribosomal proteins. Mol. Cell 59: 35-49
-
(2015)
Mol. Cell
, vol.59
, pp. 35-49
-
-
Higgins, R.1
Gendron, J.M.2
Rising, L.3
Mak, R.4
Webb, K.5
-
57
-
-
33644787880
-
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
-
Hirano S, Kawasaki M, Ura H, Kato R, Raiborg C, et al. 2006. Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting. Nat. Struct. Mol. Biol. 13: 272-77
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 272-277
-
-
Hirano, S.1
Kawasaki, M.2
Ura, H.3
Kato, R.4
Raiborg, C.5
-
58
-
-
84979730108
-
UBQLN2 mediates autophagyindependent protein aggregate clearance by the proteasome
-
Hjerpe R, Bett JS, Keuss MJ, Solovyova A, McWilliams TG, et al. 2016. UBQLN2 mediates autophagyindependent protein aggregate clearance by the proteasome. Cell 166: 935-49
-
(2016)
Cell
, vol.166
, pp. 935-949
-
-
Hjerpe, R.1
Bett, J.S.2
Keuss, M.J.3
Solovyova, A.4
McWilliams, T.G.5
-
59
-
-
85031939790
-
The Met1-linked ubiquitin machinery: Emerging themes of (de)regulation
-
Hrdinka M, Gyrd-Hansen M. 2017. The Met1-linked ubiquitin machinery: emerging themes of (de)regulation. Mol. Cell 68: 265-80
-
(2017)
Mol. Cell
, vol.68
, pp. 265-280
-
-
Hrdinka, M.1
Gyrd-Hansen, M.2
-
60
-
-
79954528832
-
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci
-
Hu Y, Scully R, Sobhian B, Xie A, Shestakova E, Livingston DM. 2011. RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev. 25: 685-700
-
(2011)
Genes Dev.
, vol.25
, pp. 685-700
-
-
Hu, Y.1
Scully, R.2
Sobhian, B.3
Xie, A.4
Shestakova, E.5
Livingston, D.M.6
-
61
-
-
36249031962
-
RNF8 transduces theDNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen MS, Grant R, Manke I, MinnK, Yu X, et al. 2007. RNF8 transduces theDNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 131: 901-14
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
-
62
-
-
78649894111
-
The N-end rule pathway ismediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases
-
Hwang CS, Shemorry A, Auerbach D, Varshavsky A. 2010. The N-end rule pathway ismediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases. Nat. Cell Biol. 12: 1177-85
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 1177-1185
-
-
Hwang, C.S.1
Shemorry, A.2
Auerbach, D.3
Varshavsky, A.4
-
63
-
-
84941956299
-
The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development
-
Illingworth RS, Moffat M, Mann AR, Read D, Hunter CJ, et al. 2015. The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development. Genes Dev. 29: 1897-902
-
(2015)
Genes Dev.
, vol.29
, pp. 1897-1902
-
-
Illingworth, R.S.1
Moffat, M.2
Mann, A.R.3
Read, D.4
Hunter, C.J.5
-
64
-
-
85021797146
-
UPR transducer BBF2H7 allows export of type II collagen in a cargo-and developmental stage-specific manner
-
Ishikawa T, Toyama T, Nakamura Y, Tamada K, Shimizu H, et al. 2017. UPR transducer BBF2H7 allows export of type II collagen in a cargo-and developmental stage-specific manner. J. Cell Biol. 216: 1761-74
-
(2017)
J. Cell Biol.
, vol.216
, pp. 1761-1774
-
-
Ishikawa, T.1
Toyama, T.2
Nakamura, Y.3
Tamada, K.4
Shimizu, H.5
-
65
-
-
85031908954
-
Structure of the Dnmt1 reader module complexed with a unique two-mono-ubiquitin mark on histone H3 reveals the basis for DNA methylation maintenance
-
350-60e7
-
Ishiyama S, Nishiyama A, Saeki Y, Moritsugu K, Morimoto D, et al. 2017. Structure of the Dnmt1 reader module complexed with a unique two-mono-ubiquitin mark on histone H3 reveals the basis for DNA methylation maintenance. Mol. Cell 68: 350-60. e7
-
(2017)
Mol. Cell
, vol.68
-
-
Ishiyama, S.1
Nishiyama, A.2
Saeki, Y.3
Moritsugu, K.4
Morimoto, D.5
-
66
-
-
84945973395
-
The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice
-
Ismail IH, Gagne JP, Genois MM, Strickfaden H, McDonald D, et al. 2015. The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice. Nat. Cell Biol. 17: 1446-57
-
(2015)
Nat. Cell Biol.
, vol.17
, pp. 1446-1457
-
-
Ismail, I.H.1
Gagne, J.P.2
Genois, M.M.3
Strickfaden, H.4
McDonald, D.5
-
67
-
-
84988013632
-
Ubiquilins chaperone and triage mitochondrial membrane proteins for degradation
-
Itakura E, Zavodszky E, Shao S, Wohlever ML, Keenan RJ, Hegde RS. 2016. Ubiquilins chaperone and triage mitochondrial membrane proteins for degradation. Mol. Cell 63: 21-33
-
(2016)
Mol. Cell
, vol.63
, pp. 21-33
-
-
Itakura, E.1
Zavodszky, E.2
Shao, S.3
Wohlever, M.L.4
Keenan, R.J.5
Hegde, R.S.6
-
68
-
-
84857377700
-
Ubiquitin-dependent regulation of COPII coat size and function
-
Jin L, Pahuja KB, Wickliffe KE, Gorur A, Baumgartel C, et al. 2012. Ubiquitin-dependent regulation of COPII coat size and function. Nature 482: 495-500
-
(2012)
Nature
, vol.482
, pp. 495-500
-
-
Jin, L.1
Pahuja, K.B.2
Wickliffe, K.E.3
Gorur, A.4
Baumgartel, C.5
-
69
-
-
43049162227
-
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex
-
Jin L, Williamson A, Banerjee S, Philipp I, Rape M. 2008. Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. Cell 133: 653-65
-
(2008)
Cell
, vol.133
, pp. 653-665
-
-
Jin, L.1
Williamson, A.2
Banerjee, S.3
Philipp, I.4
Rape, M.5
-
70
-
-
33947528891
-
Von Hippel-Lindau disease
-
Kaelin WG. 2007. Von Hippel-Lindau disease. Annu. Rev. Pathol. 2: 145-73
-
(2007)
Annu. Rev. Pathol.
, vol.2
, pp. 145-173
-
-
Kaelin, W.G.1
-
71
-
-
84901987800
-
Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression
-
Kalb R, Latwiel S, Baymaz HI, Jansen PW, Muller CW, et al. 2014. Histone H2A monoubiquitination promotes histone H3 methylation in Polycomb repression. Nat. Struct. Mol. Biol. 21: 569-71
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 569-571
-
-
Kalb, R.1
Latwiel, S.2
Baymaz, H.I.3
Jansen, P.W.4
Muller, C.W.5
-
72
-
-
4344712350
-
TAB2 and TAB3 activate the NF-B pathway through binding to polyubiquitin chains
-
Kanayama A, Seth RB, Sun L, Ea CK, Hong M, et al. 2004. TAB2 and TAB3 activate the NF-B pathway through binding to polyubiquitin chains. Mol. Cell 15: 535-48
-
(2004)
Mol. Cell
, vol.15
, pp. 535-548
-
-
Kanayama, A.1
Seth, R.B.2
Sun, L.3
Ea, C.K.4
Hong, M.5
-
73
-
-
84899539731
-
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
-
Kane LA, Lazarou M, Fogel AI, Li Y, Yamano K, et al. 2014. PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity. J. Cell Biol. 205: 143-53
-
(2014)
J. Cell Biol.
, vol.205
, pp. 143-153
-
-
Kane, L.A.1
Lazarou, M.2
Fogel, A.I.3
Li, Y.4
Yamano, K.5
-
74
-
-
85032456442
-
USP7 small-molecule inhibitors interfere with ubiquitin binding
-
Kategaya L, Di Lello P, Rouge L, Pastor R, Clark KR, et al. 2017. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature 550: 534-38
-
(2017)
Nature
, vol.550
, pp. 534-538
-
-
Kategaya, L.1
Di Lello, P.2
Rouge, L.3
Pastor, R.4
Clark, K.R.5
-
75
-
-
84899421556
-
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
-
Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, et al. 2014. Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65. Biochem. J. 460: 127-39
-
(2014)
Biochem. J.
, vol.460
, pp. 127-139
-
-
Kazlauskaite, A.1
Kondapalli, C.2
Gourlay, R.3
Campbell, D.G.4
Ritorto, M.S.5
-
76
-
-
85011636010
-
Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases
-
Keszei AF, Sicheri F. 2017. Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases. PNAS 114: 1311-16
-
(2017)
PNAS
, vol.114
, pp. 1311-1316
-
-
Keszei, A.F.1
Sicheri, F.2
-
77
-
-
84878862687
-
OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin
-
Keusekotten K, Elliott PR, Glockner L, Fiil BK, Damgaard RB, et al. 2013. OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin. Cell 153: 1312-26
-
(2013)
Cell
, vol.153
, pp. 1312-1326
-
-
Keusekotten, K.1
Elliott, P.R.2
Glockner, L.3
Fiil, B.K.4
Damgaard, R.B.5
-
78
-
-
34249950879
-
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
-
Kim H, Chen J, Yu X. 2007. Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 316: 1202-5
-
(2007)
Science
, vol.316
, pp. 1202-1205
-
-
Kim, H.1
Chen, J.2
Yu, X.3
-
79
-
-
84892802083
-
The N-terminal methionine of cellular proteins as a degradation signal
-
Kim HK, Kim RR, Oh JH, Cho H, Varshavsky A, Hwang CS. 2014. The N-terminal methionine of cellular proteins as a degradation signal. Cell 156: 158-69
-
(2014)
Cell
, vol.156
, pp. 158-169
-
-
Kim, H.K.1
Kim, R.R.2
Oh, J.H.3
Cho, H.4
Varshavsky, A.5
Hwang, C.S.6
-
80
-
-
28444463638
-
The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions
-
Kim J, Hake SB, Roeder RG. 2005. The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions. Mol. Cell 20: 759-70
-
(2005)
Mol. Cell
, vol.20
, pp. 759-770
-
-
Kim, J.1
Hake, S.B.2
Roeder, R.G.3
-
81
-
-
82455179484
-
Systematic and quantitative assessment of the ubiquitin-modified proteome
-
Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, et al. 2011. Systematic and quantitative assessment of the ubiquitin-modified proteome. Mol. Cell 44: 325-40
-
(2011)
Mol. Cell
, vol.44
, pp. 325-340
-
-
Kim, W.1
Bennett, E.J.2
Huttlin, E.L.3
Guo, A.4
Li, J.5
-
82
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas NK, Chapman JR, Nakada S, Ylanko J, Chahwan R, et al. 2007. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 318: 1637-40
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
-
83
-
-
67349231313
-
Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
-
Komander D, Reyes-Turcu F, Licchesi JD, Odenwaelder P, Wilkinson KD, Barford D. 2009. Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains. EMBO Rep. 10: 466-73
-
(2009)
EMBO Rep.
, vol.10
, pp. 466-473
-
-
Komander, D.1
Reyes-Turcu, F.2
Licchesi, J.D.3
Odenwaelder, P.4
Wilkinson, K.D.5
Barford, D.6
-
84
-
-
85026324537
-
CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides
-
Kostova KK, Hickey KL, Osuna BA, Hussmann JA, Frost A, et al. 2017. CAT-tailing as a fail-safe mechanism for efficient degradation of stalled nascent polypeptides. Science 357: 414-17
-
(2017)
Science
, vol.357
, pp. 414-417
-
-
Kostova, K.K.1
Hickey, K.L.2
Osuna, B.A.3
Hussmann, J.A.4
Frost, A.5
-
85
-
-
85009345399
-
A single Legionella effector catalyzes a multistep ubiquitination pathway to rearrange tubular endoplasmic reticulum for replication
-
Kotewicz KM, Ramabhadran V, Sjoblom N, Vogel JP, Haenssler E, et al. 2017. A single Legionella effector catalyzes a multistep ubiquitination pathway to rearrange tubular endoplasmic reticulum for replication. Cell Host Microbe 21: 169-81
-
(2017)
Cell Host Microbe
, vol.21
, pp. 169-181
-
-
Kotewicz, K.M.1
Ramabhadran, V.2
Sjoblom, N.3
Vogel, J.P.4
Haenssler, E.5
-
86
-
-
84901751574
-
Ubiquitin is phosphorylated by PINK1 to activate parkin
-
Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, et al. 2014. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 510: 162-66
-
(2014)
Nature
, vol.510
, pp. 162-166
-
-
Koyano, F.1
Okatsu, K.2
Kosako, H.3
Tamura, Y.4
Go, E.5
-
87
-
-
84961288441
-
K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of K29 polyubiquitin
-
Kristariyanto YA, Abdul Rehman SA, Campbell DG, Morrice NA, Johnson C, et al. 2015. K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of K29 polyubiquitin. Mol. Cell 58: 83-94
-
(2015)
Mol. Cell
, vol.58
, pp. 83-94
-
-
Kristariyanto, Y.A.1
Abdul Rehman, S.A.2
Campbell, D.G.3
Morrice, N.A.4
Johnson, C.5
-
88
-
-
84990210741
-
SPATA2-mediated binding of CYLD to HOIP enables CYLD recruitment to signaling complexes
-
Kupka S, De Miguel D, Draber P, Martino L, Surinova S, et al. 2016. SPATA2-mediated binding of CYLD to HOIP enables CYLD recruitment to signaling complexes. Cell Rep. 16: 2271-80
-
(2016)
Cell Rep.
, vol.16
, pp. 2271-2280
-
-
Kupka, S.1
De Miguel, D.2
Draber, P.3
Martino, L.4
Surinova, S.5
-
89
-
-
84996606975
-
USP44 is an integral component of N-CoR that contributes to gene repression by deubiquitinating histone H2B
-
Lan X, Atanassov BS, Li W, Zhang Y, Florens L, et al. 2016. USP44 is an integral component of N-CoR that contributes to gene repression by deubiquitinating histone H2B. Cell Rep. 17: 2382-93
-
(2016)
Cell Rep.
, vol.17
, pp. 2382-2393
-
-
Lan, X.1
Atanassov, B.S.2
Li, W.3
Zhang, Y.4
Florens, L.5
-
90
-
-
70350020147
-
NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain
-
Laplantine E, Fontan E, Chiaravalli J, Lopez T, Lakisic G, et al. 2009. NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain. EMBO J. 28: 2885-95
-
(2009)
EMBO J.
, vol.28
, pp. 2885-2895
-
-
Laplantine, E.1
Fontan, E.2
Chiaravalli, J.3
Lopez, T.4
Lakisic, G.5
-
91
-
-
84939804206
-
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
-
Lazarou M, Sliter DA, Kane LA, Sarraf SA, Wang C, et al. 2015. The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy. Nature 524: 309-14
-
(2015)
Nature
, vol.524
, pp. 309-314
-
-
Lazarou, M.1
Sliter, D.A.2
Kane, L.A.3
Sarraf, S.A.4
Wang, C.5
-
92
-
-
84976515858
-
Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells
-
Lee JG, Takahama S, Zhang G, Tomarev SI, Ye Y. 2016. Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells. Nat. Cell Biol. 18: 765-76
-
(2016)
Nat. Cell Biol.
, vol.18
, pp. 765-776
-
-
Lee, J.G.1
Takahama, S.2
Zhang, G.3
Tomarev, S.I.4
Ye, Y.5
-
93
-
-
0036340237
-
The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
-
Levine SS, Weiss A, Erdjument-Bromage H, ShaoZ, Tempst P, Kingston RE. 2002. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol. Cell. Biol. 22: 6070-78
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 6070-6078
-
-
Levine, S.S.1
Weiss, A.2
Erdjument-Bromage, H.3
Shao, Z.4
Tempst, P.5
Kingston, R.E.6
-
94
-
-
0032217156
-
C-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
-
Levkowitz G, Waterman H, Zamir E, Kam Z, Oved S, et al. 1998. c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor. Genes Dev. 12: 3663-74
-
(1998)
Genes Dev.
, vol.12
, pp. 3663-3674
-
-
Levkowitz, G.1
Waterman, H.2
Zamir, E.3
Kam, Z.4
Oved, S.5
-
95
-
-
55549102963
-
Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface
-
Lin CH, MacGurn JA, Chu T, Stefan CJ, Emr SD. 2008. Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell 135: 714-25
-
(2008)
Cell
, vol.135
, pp. 714-725
-
-
Lin, C.H.1
MacGurn, J.A.2
Chu, T.3
Stefan, C.J.4
Emr, S.D.5
-
96
-
-
84936139864
-
CRL2 AIDS elimination of truncated selenoproteins produced by failed UGA/Sec decoding
-
Lin HC, Ho SC, Chen YY, Khoo KH, Hsu PH, Yen HC. 2015. CRL2 aids elimination of truncated selenoproteins produced by failed UGA/Sec decoding. Science 349: 91-95
-
(2015)
Science
, vol.349
, pp. 91-95
-
-
Lin, H.C.1
Ho, S.C.2
Chen, Y.Y.3
Khoo, K.H.4
Hsu, P.H.5
Yen, H.C.6
-
97
-
-
85011659378
-
Ufd2p synthesizes branched ubiquitin chains to promote the degradation of substrates modified with atypical chains
-
Liu C, Liu W, Ye Y, Li W. 2017. Ufd2p synthesizes branched ubiquitin chains to promote the degradation of substrates modified with atypical chains. Nat. Commun. 8: 14274
-
(2017)
Nat. Commun.
, vol.8
, pp. 14274
-
-
Liu, C.1
Liu, W.2
Ye, Y.3
Li, W.4
-
98
-
-
84953637768
-
Cul3-KLHL20 ubiquitin ligase governs the turnover of ULK1 and VPS34 complexes to control autophagy termination
-
Liu CC, Lin YC, Chen YH, Chen CM, Pang LY, et al. 2016. Cul3-KLHL20 ubiquitin ligase governs the turnover of ULK1 and VPS34 complexes to control autophagy termination. Mol. Cell 61: 84-97
-
(2016)
Mol. Cell
, vol.61
, pp. 84-97
-
-
Liu, C.C.1
Lin, Y.C.2
Chen, Y.H.3
Chen, C.M.4
Pang, L.Y.5
-
99
-
-
84909606327
-
Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex
-
Lyumkis D, Oliveira dos Passos D, Tahara EB, Webb K, Bennett EJ, et al. 2014. Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex. PNAS 111: 15981-86
-
(2014)
PNAS
, vol.111
, pp. 15981-15986
-
-
Lyumkis, D.1
Oliveira Dos Passos, D.2
Tahara, E.B.3
Webb, K.4
Bennett, E.J.5
-
100
-
-
81855183664
-
TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor
-
MacGurn JA, Hsu PC, Smolka MB, Emr SD. 2011. TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. Cell 147: 1104-17
-
(2011)
Cell
, vol.147
, pp. 1104-1117
-
-
MacGurn, J.A.1
Hsu, P.C.2
Smolka, M.B.3
Emr, S.D.4
-
101
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N, Bekker-Jensen S, Faustrup H, Melander F, Bartek J, et al. 2007. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131: 887-900
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
-
102
-
-
84885576570
-
The ubiquitin ligase parkin mediates resistance to intracellular pathogens
-
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, et al. 2013. The ubiquitin ligase parkin mediates resistance to intracellular pathogens. Nature 501: 512-16
-
(2013)
Nature
, vol.501
, pp. 512-516
-
-
Manzanillo, P.S.1
Ayres, J.S.2
Watson, R.O.3
Collins, A.C.4
Souza, G.5
-
103
-
-
84892895021
-
PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry
-
Marechal A, Li JM, Ji XY, Wu CS, Yazinski SA, et al. 2014. PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Mol. Cell 53: 235-46
-
(2014)
Mol. Cell
, vol.53
, pp. 235-246
-
-
Marechal, A.1
Li, J.M.2
Ji, X.Y.3
Wu, C.S.4
Yazinski, S.A.5
-
104
-
-
84866388311
-
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
-
Mattiroli F, Vissers JH, van Dijk WJ, Ikpa P, Citterio E, et al. 2012. RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Cell 150: 1182-95
-
(2012)
Cell
, vol.150
, pp. 1182-1195
-
-
Mattiroli, F.1
Vissers, J.H.2
Van Dijk, W.J.3
Ikpa, P.4
Citterio, E.5
-
105
-
-
4143080425
-
AMSH is an endosome-associated ubiquitin isopeptidase
-
McCullough J, Clague MJ, Urbe S. 2004. AMSH is an endosome-associated ubiquitin isopeptidase. J. Cell Biol. 166: 487-92
-
(2004)
J. Cell Biol.
, vol.166
, pp. 487-492
-
-
McCullough, J.1
Clague, M.J.2
Urbe, S.3
-
106
-
-
84908408859
-
Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome
-
McGinty RK, Henrici RC, Tan S. 2014. Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome. Nature 514: 591-96
-
(2014)
Nature
, vol.514
, pp. 591-596
-
-
McGinty, R.K.1
Henrici, R.C.2
Tan, S.3
-
107
-
-
84990985666
-
Regulation of the CUL3 ubiquitin ligase by a calcium-dependent co-adaptor
-
525-38e14
-
McGourty CA, Akopian D, Walsh C, Gorur A, Werner A, et al. 2016. Regulation of the CUL3 ubiquitin ligase by a calcium-dependent co-adaptor. Cell 167: 525-38. e14
-
(2016)
Cell
, vol.167
-
-
McGourty, C.A.1
Akopian, D.2
Walsh, C.3
Gorur, A.4
Werner, A.5
-
108
-
-
85021674924
-
Mechanisms of deubiquitinase specificity and regulation
-
Mevissen TET, Komander D. 2017. Mechanisms of deubiquitinase specificity and regulation. Annu. Rev. Biochem. 86: 159-92
-
(2017)
Annu. Rev. Biochem.
, vol.86
, pp. 159-192
-
-
Mevissen, T.E.T.1
Komander, D.2
-
109
-
-
84900337781
-
Enhanced protein degradation by branched ubiquitin chains
-
Meyer HJ, Rape M. 2014. Enhanced protein degradation by branched ubiquitin chains. Cell 157: 910-21
-
(2014)
Cell
, vol.157
, pp. 910-921
-
-
Meyer, H.J.1
Rape, M.2
-
110
-
-
85029693774
-
Ubiquitin linkage-specific affimers reveal insights into K6-linked ubiquitin signaling
-
233-46e5
-
Michel MA, Swatek KN, Hospenthal MK, Komander D. 2017. Ubiquitin linkage-specific affimers reveal insights into K6-linked ubiquitin signaling. Mol. Cell 68: 233-46. e5
-
(2017)
Mol. Cell
, vol.68
-
-
Michel, M.A.1
Swatek, K.N.2
Hospenthal, M.K.3
Komander, D.4
-
111
-
-
79551500427
-
Targeted large-scale analysis of protein acetylation
-
Mischerikow N, Heck AJ. 2011. Targeted large-scale analysis of protein acetylation. Proteomics 11: 571-89
-
(2011)
Proteomics
, vol.11
, pp. 571-589
-
-
Mischerikow, N.1
Heck, A.J.2
-
112
-
-
0141744750
-
STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif
-
Mizuno E, Kawahata K, KatoM, Kitamura N, KomadaM. 2003. STAM proteins bind ubiquitinated proteins on the early endosome via the VHS domain and ubiquitin-interacting motif. Mol. Biol. Cell 14: 3675-89
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3675-3689
-
-
Mizuno, E.1
Kawahata, K.2
Kato, M.3
Kitamura, N.4
Komada, M.5
-
113
-
-
77955867565
-
Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1
-
Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, et al. 2010. Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1. Nature 466: 941-46
-
(2010)
Nature
, vol.466
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
-
114
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D, Tanaka A, Suen DF, Youle RJ. 2008. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 183: 795-803
-
(2008)
J. Cell Biol.
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
115
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra DP, Jin SM, Tanaka A, Suen DF, Gautier CA, et al. 2010. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLOS Biol. 8: e1000298
-
(2010)
PLOS Biol.
, vol.8
, pp. e1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
-
116
-
-
85026783128
-
UBE2O remodels the proteome during terminal erythroid differentiation
-
Nguyen AT, Prado MA, Schmidt PJ, Sendamarai AK, Wilson-Grady JT, et al. 2017. UBE2O remodels the proteome during terminal erythroid differentiation. Science 357: eaan0218
-
(2017)
Science
, vol.357
, pp. eaan0218
-
-
Nguyen, A.T.1
Prado, M.A.2
Schmidt, P.J.3
Sendamarai, A.K.4
Wilson-Grady, J.T.5
-
117
-
-
84885577142
-
Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication
-
Nishiyama A, Yamaguchi L, Sharif J, Johmura Y, Kawamura T, et al. 2013. Uhrf1-dependent H3K23 ubiquitylation couples maintenance DNA methylation and replication. Nature 502: 249-53
-
(2013)
Nature
, vol.502
, pp. 249-253
-
-
Nishiyama, A.1
Yamaguchi, L.2
Sharif, J.3
Johmura, Y.4
Kawamura, T.5
-
118
-
-
85019121520
-
LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-B
-
Noad J, von der Malsburg A, Pathe C, Michel MA, KomanderD, Randow F. 2017. LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-B. Nat. Microbiol. 2: 17063
-
(2017)
Nat. Microbiol.
, vol.2
, pp. 17063
-
-
Noad, J.1
Von Der Malsburg, A.2
Pathe, C.3
Michel, M.A.4
Komander, D.5
Randow, F.6
-
119
-
-
84994895357
-
The K48-K63 branched ubiquitin chain regulates NF-B signaling
-
Ohtake F, Saeki Y, Ishido S, Kanno J, Tanaka K. 2016. The K48-K63 branched ubiquitin chain regulates NF-B signaling. Mol. Cell 64: 251-66
-
(2016)
Mol. Cell
, vol.64
, pp. 251-266
-
-
Ohtake, F.1
Saeki, Y.2
Ishido, S.3
Kanno, J.4
Tanaka, K.5
-
120
-
-
85041949067
-
K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains
-
In press
-
Ohtake F, Tsuchiya H, Saeki Y, Tanaka K. 2018. K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains. PNAS. In press
-
(2018)
PNAS.
-
-
Ohtake, F.1
Tsuchiya, H.2
Saeki, Y.3
Tanaka, K.4
-
121
-
-
84874351566
-
A two-step mechanism for TRF2-mediated chromosome-end protection
-
Okamoto K, Bartocci C, Ouzounov I, Diedrich JK, Yates JR 3rd, Denchi EL. 2013. A two-step mechanism for TRF2-mediated chromosome-end protection. Nature 494: 502-5
-
(2013)
Nature
, vol.494
, pp. 502-505
-
-
Okamoto, K.1
Bartocci, C.2
Ouzounov, I.3
Diedrich, J.K.4
Yates, J.R.5
Denchi, E.L.6
-
122
-
-
84929691103
-
Defining roles of PARKIN and ubiquitin phosphorylation byPINK1 in mitochondrial quality control using a ubiquitin replacement strategy
-
Ordureau A, Heo JM, Duda DM, Paulo JA, Olszewski JL, et al. 2015. Defining roles of PARKIN and ubiquitin phosphorylation byPINK1 in mitochondrial quality control using a ubiquitin replacement strategy. PNAS 112: 6637-42
-
(2015)
PNAS
, vol.112
, pp. 6637-6642
-
-
Ordureau, A.1
Heo, J.M.2
Duda, D.M.3
Paulo, J.A.4
Olszewski, J.L.5
-
123
-
-
84922434418
-
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis
-
Ordureau A, Sarraf SA, Duda DM, Heo JM, Jedrychowski MP, et al. 2014. Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis. Mol. Cell 56: 360-75
-
(2014)
Mol. Cell
, vol.56
, pp. 360-375
-
-
Ordureau, A.1
Sarraf, S.A.2
Duda, D.M.3
Heo, J.M.4
Jedrychowski, M.P.5
-
124
-
-
84898052474
-
Mitosis inhibits DNA double-strand break repair to guard against telomere fusions
-
Orthwein A, Fradet-Turcotte A, Noordermeer SM, Canny MD, Brun CM, et al. 2014. Mitosis inhibits DNA double-strand break repair to guard against telomere fusions. Science 344: 189-93
-
(2014)
Science
, vol.344
, pp. 189-193
-
-
Orthwein, A.1
Fradet-Turcotte, A.2
Noordermeer, S.M.3
Canny, M.D.4
Brun, C.M.5
-
125
-
-
84950294519
-
A mechanism for the suppression of homologous recombination in G1 cells
-
Orthwein A, Noordermeer SM, Wilson MD, Landry S, Enchev RI, et al. 2015. A mechanism for the suppression of homologous recombination in G1 cells. Nature 528: 422-26
-
(2015)
Nature
, vol.528
, pp. 422-426
-
-
Orthwein, A.1
Noordermeer, S.M.2
Wilson, M.D.3
Landry, S.4
Enchev, R.I.5
-
126
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, et al. 2007. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 447: 859-63
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
-
127
-
-
84864919890
-
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks
-
Panier S, Ichijima Y, Fradet-Turcotte A, Leung CC, Kaustov L, et al. 2012. Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks. Mol. Cell 47: 383-95
-
(2012)
Mol. Cell
, vol.47
, pp. 383-395
-
-
Panier, S.1
Ichijima, Y.2
Fradet-Turcotte, A.3
Leung, C.C.4
Kaustov, L.5
-
128
-
-
85045950070
-
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity
-
Pao KC, Wood NT, Knebel A, Rafie K, Stanley M, et al. 2018. Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity. Nature 556: 381-85
-
(2018)
Nature
, vol.556
, pp. 381-385
-
-
Pao, K.C.1
Wood, N.T.2
Knebel, A.3
Rafie, K.4
Stanley, M.5
-
129
-
-
84897954522
-
The E3 ligaseCbl-b andTAMreceptors regulate cancer metastasis via natural killer cells
-
PaolinoM, Choidas A, Wallner S, Pranjic B, Uribesalgo I, et al. 2014. The E3 ligaseCbl-b andTAMreceptors regulate cancer metastasis via natural killer cells. Nature 507: 508-12
-
(2014)
Nature
, vol.507
, pp. 508-512
-
-
Paolino, M.1
Choidas, A.2
Wallner, S.3
Pranjic, B.4
Uribesalgo, I.5
-
130
-
-
33646691283
-
Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II
-
Pavri R, Zhu B, Li G, Trojer P, Mandal S, et al. 2006. Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell 125: 703-17
-
(2006)
Cell
, vol.125
, pp. 703-717
-
-
Pavri, R.1
Zhu, B.2
Li, G.3
Trojer, P.4
Mandal, S.5
-
131
-
-
84938149171
-
Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation
-
Pengelly AR, Kalb R, Finkl K, Muller J. 2015. Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation. Genes Dev. 29: 1487-92
-
(2015)
Genes Dev.
, vol.29
, pp. 1487-1492
-
-
Pengelly, A.R.1
Kalb, R.2
Finkl, K.3
Muller, J.4
-
132
-
-
71449123070
-
Detection of sequential polyubiquitylation on a millisecond timescale
-
Pierce NW, Kleiger G, Shan SO, Deshaies RJ. 2009. Detection of sequential polyubiquitylation on a millisecond timescale. Nature 462: 615-19
-
(2009)
Nature
, vol.462
, pp. 615-619
-
-
Pierce, N.W.1
Kleiger, G.2
Shan, S.O.3
Deshaies, R.J.4
-
133
-
-
85026748555
-
Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella
-
Polajnar M, Dietz MS, Heilemann M, Behrends C. 2017. Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella. EMBO Rep. 18: 1572-85
-
(2017)
EMBO Rep.
, vol.18
, pp. 1572-1585
-
-
Polajnar, M.1
Dietz, M.S.2
Heilemann, M.3
Behrends, C.4
-
134
-
-
0037187597
-
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins
-
Polo S, Sigismund S, Faretta M, Guidi M, Capua MR, et al. 2002. A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins. Nature 416: 451-55
-
(2002)
Nature
, vol.416
, pp. 451-455
-
-
Polo, S.1
Sigismund, S.2
Faretta, M.3
Guidi, M.4
Capua, M.R.5
-
135
-
-
34648840192
-
SUMO-targeted ubiquitin ligases in genome stability
-
Prudden J, Pebernard S, RaffaG, Slavin DA, Perry JJ, et al. 2007. SUMO-targeted ubiquitin ligases in genome stability. EMBO J. 26: 4089-101
-
(2007)
EMBO J.
, vol.26
, pp. 4089-4101
-
-
Prudden, J.1
Pebernard, S.2
Raffa, G.3
Slavin, D.A.4
Perry, J.J.5
-
136
-
-
84978880194
-
The molecular basis for ubiquitin and ubiquitin-like specificities in bacterial effector proteases
-
Pruneda JN, Durkin CH, Geurink PP, Ovaa H, Santhanam B, et al. 2016. The molecular basis for ubiquitin and ubiquitin-like specificities in bacterial effector proteases. Mol. Cell 63: 261-76
-
(2016)
Mol. Cell
, vol.63
, pp. 261-276
-
-
Pruneda, J.N.1
Durkin, C.H.2
Geurink, P.P.3
Ovaa, H.4
Santhanam, B.5
-
137
-
-
84874765320
-
Encoding and decoding cellular information through signaling dynamics
-
Purvis JE, Lahav G. 2013. Encoding and decoding cellular information through signaling dynamics. Cell 152: 945-56
-
(2013)
Cell
, vol.152
, pp. 945-956
-
-
Purvis, J.E.1
Lahav, G.2
-
138
-
-
84966440977
-
Mechanism ofAPC/CCDC20 activation by mitotic phosphorylation
-
Qiao R, Weissmann F, YamaguchiM, Brown NG, VanderLindenR, et al. 2016. Mechanism ofAPC/CCDC20 activation by mitotic phosphorylation. PNAS 113: E2570-78
-
(2016)
PNAS
, vol.113
, pp. E2570-E2578
-
-
Qiao, R.1
Weissmann, F.2
Yamaguchi, M.3
Brown, N.G.4
VanderLinden, R.5
-
139
-
-
84938747262
-
DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination
-
Qin W, Wolf P, Liu N, Link S, Smets M, et al. 2015. DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination. Cell Res. 25: 911-29
-
(2015)
Cell Res.
, vol.25
, pp. 911-929
-
-
Qin, W.1
Wolf, P.2
Liu, N.3
Link, S.4
Smets, M.5
-
140
-
-
84966350690
-
Ubiquitination independent of E1 and E2 enzymes by bacterial effectors
-
Qiu J, Sheedlo MJ, Yu K, Tan Y, Nakayasu ES, et al. 2016. Ubiquitination independent of E1 and E2 enzymes by bacterial effectors. Nature 533: 120-24
-
(2016)
Nature
, vol.533
, pp. 120-124
-
-
Qiu, J.1
Sheedlo, M.J.2
Yu, K.3
Tan, Y.4
Nakayasu, E.S.5
-
141
-
-
62549155321
-
Specific recognition of linear ubiquitin chains by NEMO is important for NF-B activation
-
Rahighi S, Ikeda F, Kawasaki M, Akutsu M, Suzuki N, et al. 2009. Specific recognition of linear ubiquitin chains by NEMO is important for NF-B activation. Cell 136: 1098-109
-
(2009)
Cell
, vol.136
, pp. 1098-1109
-
-
Rahighi, S.1
Ikeda, F.2
Kawasaki, M.3
Akutsu, M.4
Suzuki, N.5
-
142
-
-
85038349916
-
Ubiquitylation at the crossroads of development and disease
-
Rape M. 2017. Ubiquitylation at the crossroads of development and disease. Nat. Rev. Mol. Cell Biol. 19: 59-70
-
(2017)
Nat. Rev. Mol. Cell Biol.
, vol.19
, pp. 59-70
-
-
Rape, M.1
-
143
-
-
0035977095
-
Mobilization of processed, membranetethered SPT23 transcription factor by CDC48UFD1/NPL4, a ubiquitin-selective chaperone
-
Rape M, Hoppe T, Gorr I, Kalocay M, Richly H, Jentsch S. 2001. Mobilization of processed, membranetethered SPT23 transcription factor by CDC48UFD1/NPL4, a ubiquitin-selective chaperone. Cell 107: 667-77
-
(2001)
Cell
, vol.107
, pp. 667-677
-
-
Rape, M.1
Hoppe, T.2
Gorr, I.3
Kalocay, M.4
Richly, H.5
Jentsch, S.6
-
144
-
-
30344466977
-
The processivity of multiubiquitination by the APC determines the order of substrate degradation
-
Rape M, Reddy SK, Kirschner MW. 2006. The processivity of multiubiquitination by the APC determines the order of substrate degradation. Cell 124: 89-103
-
(2006)
Cell
, vol.124
, pp. 89-103
-
-
Rape, M.1
Reddy, S.K.2
Kirschner, M.W.3
-
145
-
-
84879390723
-
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis
-
Rivkin E, Almeida SM, Ceccarelli DF, Juang YC, MacLean TA, et al. 2013. The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature 498: 318-24
-
(2013)
Nature
, vol.498
, pp. 318-324
-
-
Rivkin, E.1
Almeida, S.M.2
Ceccarelli, D.F.3
Juang, Y.C.4
MacLean, T.A.5
-
146
-
-
84904567733
-
Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6
-
Rodrigo-Brenni MC, Gutierrez E, Hegde RS. 2014. Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6. Mol. Cell 55: 227-37
-
(2014)
Mol. Cell
, vol.55
, pp. 227-237
-
-
Rodrigo-Brenni, M.C.1
Gutierrez, E.2
Hegde, R.S.3
-
147
-
-
78650731442
-
Disorder targets misorder in nuclear quality control degradation: A disordered ubiquitin ligase directly recognizes its misfolded substrates
-
Rosenbaum JC, Fredrickson EK, Oeser ML, Garrett-Engele CM, Locke MN, et al. 2011. Disorder targets misorder in nuclear quality control degradation: A disordered ubiquitin ligase directly recognizes its misfolded substrates. Mol. Cell 41: 93-106
-
(2011)
Mol. Cell
, vol.41
, pp. 93-106
-
-
Rosenbaum, J.C.1
Fredrickson, E.K.2
Oeser, M.L.3
Garrett-Engele, C.M.4
Locke, M.N.5
-
148
-
-
84982094835
-
An evolutionarily conserved pathway controls proteasome homeostasis
-
Rousseau A, Bertolotti A. 2016. An evolutionarily conserved pathway controls proteasome homeostasis. Nature 536: 184-89
-
(2016)
Nature
, vol.536
, pp. 184-189
-
-
Rousseau, A.1
Bertolotti, A.2
-
149
-
-
84862818454
-
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response
-
Sanada T, Kim M, Mimuro H, Suzuki M, Ogawa M, et al. 2012. The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response. Nature 483: 623-26
-
(2012)
Nature
, vol.483
, pp. 623-626
-
-
Sanada, T.1
Kim, M.2
Mimuro, H.3
Suzuki, M.4
Ogawa, M.5
-
150
-
-
84876296881
-
Landscape of the PARKINdependent ubiquitylome in response to mitochondrial depolarization
-
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, et al. 2013. Landscape of the PARKINdependent ubiquitylome in response to mitochondrial depolarization. Nature 496: 372-76
-
(2013)
Nature
, vol.496
, pp. 372-376
-
-
Sarraf, S.A.1
Raman, M.2
Guarani-Pereira, V.3
Sowa, M.E.4
Huttlin, E.L.5
-
151
-
-
84959523268
-
USP9X controls EGFR fate by deubiquitinating the endocytic adaptor Eps15
-
Savio MG, Wollscheid N, Cavallaro E, Algisi V, Di Fiore PP, et al. 2016. USP9X controls EGFR fate by deubiquitinating the endocytic adaptor Eps15. Curr. Biol. 26: 173-83
-
(2016)
Curr. Biol.
, vol.26
, pp. 173-183
-
-
Savio, M.G.1
Wollscheid, N.2
Cavallaro, E.3
Algisi, V.4
Di Fiore, P.P.5
-
152
-
-
0027358723
-
TheHPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
-
ScheffnerM, Huibregtse JM, Vierstra RD, Howley PM. 1993. TheHPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75: 495-505
-
(1993)
Cell
, vol.75
, pp. 495-505
-
-
Scheffner, M.1
Huibregtse, J.M.2
Vierstra, R.D.3
Howley, P.M.4
-
153
-
-
77952429798
-
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
-
Scheuermann JC, de Ayala Alonso AG, Oktaba K, Ly-Hartig N, McGinty RK, et al. 2010. Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature 465: 243-47
-
(2010)
Nature
, vol.465
, pp. 243-247
-
-
Scheuermann, J.C.1
De Ayala Alonso, A.G.2
Oktaba, K.3
Ly-Hartig, N.4
McGinty, R.K.5
-
154
-
-
84945937533
-
Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair
-
Schmidt CK, Galanty Y, Sczaniecka-Clift M, Coates J, Jhujh S, et al. 2015. Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair. Nat. Cell Biol. 17: 1458-70
-
(2015)
Nat. Cell Biol.
, vol.17
, pp. 1458-1470
-
-
Schmidt, C.K.1
Galanty, Y.2
Sczaniecka-Clift, M.3
Coates, J.4
Jhujh, S.5
-
155
-
-
85041123859
-
Structure of PINK1 in complex with its substrate ubiquitin
-
Schubert AF, Gladkova C, Pardon E, Wagstaff JL, Freund SMV, et al. 2017. Structure of PINK1 in complex with its substrate ubiquitin. Nature 552: 51-56
-
(2017)
Nature
, vol.552
, pp. 51-56
-
-
Schubert, A.F.1
Gladkova, C.2
Pardon, E.3
Wagstaff, J.L.4
Freund, S.M.V.5
-
156
-
-
84924777167
-
Structure and assembly pathway of the ribosome quality control complex
-
Shao S, Brown A, Santhanam B, Hegde RS. 2015. Structure and assembly pathway of the ribosome quality control complex. Mol. Cell 57: 433-44
-
(2015)
Mol. Cell
, vol.57
, pp. 433-444
-
-
Shao, S.1
Brown, A.2
Santhanam, B.3
Hegde, R.S.4
-
158
-
-
84878857004
-
Listerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociation
-
Shao S, von der Malsburg K, Hegde RS. 2013. Listerin-dependent nascent protein ubiquitination relies on ribosome subunit dissociation. Mol. Cell 50: 637-48
-
(2013)
Mol. Cell
, vol.50
, pp. 637-648
-
-
Shao, S.1
Von Der Malsburg, K.2
Hegde, R.S.3
-
159
-
-
84878195272
-
Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway
-
Shemorry A, Hwang CS, Varshavsky A. 2013. Control of protein quality and stoichiometries by N-terminal acetylation and the N-end rule pathway. Mol. Cell 50: 540-51
-
(2013)
Mol. Cell
, vol.50
, pp. 540-551
-
-
Shemorry, A.1
Hwang, C.S.2
Varshavsky, A.3
-
160
-
-
84922479672
-
Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains
-
Shen PS, Park J, Qin Y, Li X, Parsawar K, et al. 2015. Protein synthesis. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Science 347: 75-78
-
(2015)
Science
, vol.347
, pp. 75-78
-
-
Shen, P.S.1
Park, J.2
Qin, Y.3
Li, X.4
Parsawar, K.5
-
161
-
-
78650253267
-
Ubiquitylation of anERADsubstrate occurs on multiple types of amino acids
-
Shimizu Y, Okuda-Shimizu Y, Hendershot LM. 2010. Ubiquitylation of anERADsubstrate occurs on multiple types of amino acids. Mol. Cell 40: 917-26
-
(2010)
Mol. Cell
, vol.40
, pp. 917-926
-
-
Shimizu, Y.1
Okuda-Shimizu, Y.2
Hendershot, L.M.3
-
162
-
-
79955631150
-
Autophagy in the cellular energetic balance
-
Singh R, Cuervo AM. 2011. Autophagy in the cellular energetic balance. Cell Metab. 13: 495-504
-
(2011)
Cell Metab.
, vol.13
, pp. 495-504
-
-
Singh, R.1
Cuervo, A.M.2
-
163
-
-
84878260314
-
Mechanisms and function of substrate recruitment by F-box proteins
-
Skaar JR, Pagan JK, Pagano M. 2013. Mechanisms and function of substrate recruitment by F-box proteins. Nat. Rev. Mol. Cell Biol. 14: 369-81
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 369-381
-
-
Skaar, J.R.1
Pagan, J.K.2
Pagano, M.3
-
164
-
-
81355150892
-
Direct, noncatalytic mechanism of IKK inhibition by A20
-
Skaug B, Chen J, Du F, He J, Ma A, Chen ZJ. 2011. Direct, noncatalytic mechanism of IKK inhibition by A20. Mol. Cell 44: 559-71
-
(2011)
Mol. Cell
, vol.44
, pp. 559-571
-
-
Skaug, B.1
Chen, J.2
Du, F.3
He, J.4
Ma, A.5
Chen, Z.J.6
-
165
-
-
34249949779
-
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
-
Sobhian B, ShaoG, Lilli DR, Culhane AC, Moreau LA, et al. 2007. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 316: 1198-202
-
(2007)
Science
, vol.316
, pp. 1198-1202
-
-
Sobhian, B.1
Shao, G.2
Lilli, D.R.3
Culhane, A.C.4
Moreau, L.A.5
-
166
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa ME, Bennett EJ, Gygi SP, Harper JW. 2009. Defining the human deubiquitinating enzyme interaction landscape. Cell 138: 389-403
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
167
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart GS, Panier S, Townsend K, Al-Hakim AK, Kolas NK, et al. 2009. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 136: 420-34
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
-
168
-
-
84988530002
-
A conserved qualitycontrol pathway that mediates degradation of unassembled ribosomal proteins
-
Sung MK, Porras-Yakushi TR, Reitsma JM, Huber FM, Sweredoski MJ, et al. 2016. A conserved qualitycontrol pathway that mediates degradation of unassembled ribosomal proteins. eLife 5: e19105
-
(2016)
ELife
, vol.5
, pp. e19105
-
-
Sung, M.K.1
Porras-Yakushi, T.R.2
Reitsma, J.M.3
Huber, F.M.4
Sweredoski, M.J.5
-
169
-
-
85018502931
-
The ubiquitin ligase CHIP integrates proteostasis and aging by regulation of insulin receptor turnover
-
470-82e13
-
Tawo R, Pokrzywa W, Kevei E, Akyuz ME, Balaji V, et al. 2017. The ubiquitin ligase CHIP integrates proteostasis and aging by regulation of insulin receptor turnover. Cell 169: 470-82. e13
-
(2017)
Cell
, vol.169
-
-
Tawo, R.1
Pokrzywa, W.2
Kevei, E.3
Akyuz, M.E.4
Balaji, V.5
-
170
-
-
85032449127
-
Germlinemutations affecting the histone H4 core cause a developmental syndrome by altering DNA damage response and cell cycle control
-
Tessadori F, Giltay JC, Hurst JA, Massink MP, Duran K, et al. 2017. Germlinemutations affecting the histone H4 core cause a developmental syndrome by altering DNA damage response and cell cycle control. Nat. Genet. 49: 1642-46
-
(2017)
Nat. Genet.
, vol.49
, pp. 1642-1646
-
-
Tessadori, F.1
Giltay, J.C.2
Hurst, J.A.3
Massink, M.P.4
Duran, K.5
-
171
-
-
84946079065
-
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
-
Thorslund T, Ripplinger A, Hoffmann S, Wild T, Uckelmann M, et al. 2015. Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage. Nature 527: 389-93
-
(2015)
Nature
, vol.527
, pp. 389-393
-
-
Thorslund, T.1
Ripplinger, A.2
Hoffmann, S.3
Wild, T.4
Uckelmann, M.5
-
172
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-B activation
-
Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, et al. 2009. Involvement of linear polyubiquitylation of NEMO in NF-B activation. Nat. Cell Biol. 11: 123-32
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
Satomi, Y.4
Kirisako, T.5
-
173
-
-
85032433305
-
Molecular basis ofUSP7 inhibition by selective small-molecule inhibitors
-
Turnbull AP, Ioannidis S, KrajewskiWW, Pinto-Fernandez A, HerideC, et al. 2017. Molecular basis ofUSP7 inhibition by selective small-molecule inhibitors. Nature 550: 481-86
-
(2017)
Nature
, vol.550
, pp. 481-486
-
-
Turnbull, A.P.1
Ioannidis, S.2
Krajewski, W.W.3
Pinto-Fernandez, A.4
Heride, C.5
-
174
-
-
85040792488
-
USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A
-
Uckelmann M, Densham RM, Baas R, Winterwerp HHK, Fish A, et al. 2018. USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A. Nat. Commun. 9: 229
-
(2018)
Nat. Commun.
, vol.9
, pp. 229
-
-
Uckelmann, M.1
Densham, R.M.2
Baas, R.3
Winterwerp, H.H.K.4
Fish, A.5
-
175
-
-
84866300942
-
Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells
-
van Wijk SJ, Fiskin E, Putyrski M, Pampaloni F, Hou J, et al. 2012. Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells. Mol. Cell 47: 797-809
-
(2012)
Mol. Cell
, vol.47
, pp. 797-809
-
-
Van Wijk, S.J.1
Fiskin, E.2
Putyrski, M.3
Pampaloni, F.4
Hou, J.5
-
176
-
-
85019111402
-
Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-B and restricts bacterial proliferation
-
vanWijk SJL, Fricke F, Herhaus L, Gupta J, Hotte K, et al. 2017. Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-B and restricts bacterial proliferation. Nat. Microbiol. 2: 17066
-
(2017)
Nat. Microbiol.
, vol.2
, pp. 17066
-
-
VanWijk, S.J.L.1
Fricke, F.2
Herhaus, L.3
Gupta, J.4
Hotte, K.5
-
177
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, et al. 2007. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 316: 1194-98
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
-
178
-
-
0035913278
-
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
-
Wang C, Deng L, Hong M, Akkaraju GR, Inoue J, Chen ZJ. 2001. TAK1 is a ubiquitin-dependent kinase of MKK and IKK. Nature 412: 346-51
-
(2001)
Nature
, vol.412
, pp. 346-351
-
-
Wang, C.1
Deng, L.2
Hong, M.3
Akkaraju, G.R.4
Inoue, J.5
Chen, Z.J.6
-
179
-
-
84883229070
-
A cotranslational ubiquitination pathway for quality control of misfolded proteins
-
Wang F, Durfee LA, Huibregtse JM. 2013. A cotranslational ubiquitination pathway for quality control of misfolded proteins. Mol. Cell 50: 368-78
-
(2013)
Mol. Cell
, vol.50
, pp. 368-378
-
-
Wang, F.1
Durfee, L.A.2
Huibregtse, J.M.3
-
180
-
-
7244234099
-
Role of histoneH2A ubiquitination in Polycomb silencing
-
WangH, WangL, Erdjument-BromageH, Vidal M, Tempst P, et al. 2004. Role of histoneH2A ubiquitination in Polycomb silencing. Nature 431: 873-78
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
Wang, L.2
Erdjument-Bromage, H.3
Vidal, M.4
Tempst, P.5
-
181
-
-
83255185097
-
Ubiquitination of substrates by esterification
-
Wang X, Herr RA, Hansen TH. 2012. Ubiquitination of substrates by esterification. Traffic 13: 19-24
-
(2012)
Traffic
, vol.13
, pp. 19-24
-
-
Wang, X.1
Herr, R.A.2
Hansen, T.H.3
-
182
-
-
84939795423
-
Mechanism of phospho-ubiquitin-induced PARKIN activation
-
Wauer T, SimicekM, Schubert A, Komander D. 2015a. Mechanism of phospho-ubiquitin-induced PARKIN activation. Nature 524: 370-74
-
(2015)
Nature
, vol.524
, pp. 370-374
-
-
Wauer, T.1
Simicek, M.2
Schubert, A.3
Komander, D.4
-
183
-
-
84922235969
-
Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
-
Wauer T, Swatek KN, Wagstaff JL, Gladkova C, Pruneda JN, et al. 2015b. Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis. EMBO J. 34: 307-25
-
(2015)
EMBO J.
, vol.34
, pp. 307-325
-
-
Wauer, T.1
Swatek, K.N.2
Wagstaff, J.L.3
Gladkova, C.4
Pruneda, J.N.5
-
184
-
-
84899980203
-
Regulation of clathrin-mediated endocytosis by dynamic ubiquitination and deubiquitination
-
Weinberg JS, Drubin DG. 2014. Regulation of clathrin-mediated endocytosis by dynamic ubiquitination and deubiquitination. Curr. Biol. 24: 951-59
-
(2014)
Curr. Biol.
, vol.24
, pp. 951-959
-
-
Weinberg, J.S.1
Drubin, D.G.2
-
185
-
-
2942650133
-
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
-
Welcker M, Orian A, Jin J, Grim JE, Harper JW, et al. 2004. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. PNAS 101: 9085-90
-
(2004)
PNAS
, vol.101
, pp. 9085-9090
-
-
Welcker, M.1
Orian, A.2
Jin, J.3
Grim, J.E.4
Harper, J.W.5
-
186
-
-
79957949190
-
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
-
Wenzel DM, Lissounov A, Brzovic PS, Klevit RE. 2011. UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature 474: 105-8
-
(2011)
Nature
, vol.474
, pp. 105-108
-
-
Wenzel, D.M.1
Lissounov, A.2
Brzovic, P.S.3
Klevit, R.E.4
-
187
-
-
84942525608
-
Cell-fate determination by ubiquitin-dependent regulation of translation
-
Werner A, Iwasaki S, McGourty CA, Medina-Ruiz S, Teerikorpi N, et al. 2015. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature 525: 523-27
-
(2015)
Nature
, vol.525
, pp. 523-527
-
-
Werner, A.1
Iwasaki, S.2
McGourty, C.A.3
Medina-Ruiz, S.4
Teerikorpi, N.5
-
188
-
-
84951176357
-
Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation
-
Wertz IE, Newton K, Seshasayee D, Kusam S, Lam C, et al. 2015. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation. Nature 528: 370-75
-
(2015)
Nature
, vol.528
, pp. 370-375
-
-
Wertz, I.E.1
Newton, K.2
Seshasayee, D.3
Kusam, S.4
Lam, C.5
-
189
-
-
79952290609
-
Themechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2
-
Wickliffe KE, Lorenz S, Wemmer DE, Kuriyan J, RapeM. 2011. Themechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2. Cell 144: 769-81
-
(2011)
Cell
, vol.144
, pp. 769-781
-
-
Wickliffe, K.E.1
Lorenz, S.2
Wemmer, D.E.3
Kuriyan, J.4
Rape, M.5
-
190
-
-
79960804104
-
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
-
Wild P, Farhan H, McEwan DG, Wagner S, Rogov VV, et al. 2011. Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. Science 333: 228-33
-
(2011)
Science
, vol.333
, pp. 228-233
-
-
Wild, P.1
Farhan, H.2
McEwan, D.G.3
Wagner, S.4
Rogov, V.V.5
-
192
-
-
84982791184
-
The structural basis of modified nucleosome recognition by 53BP1
-
Wilson MD, Benlekbir S, Fradet-Turcotte A, Sherker A, Julien JP, et al. 2016. The structural basis of modified nucleosome recognition by 53BP1. Nature 536: 100-3
-
(2016)
Nature
, vol.536
, pp. 100-103
-
-
Wilson, M.D.1
Benlekbir, S.2
Fradet-Turcotte, A.3
Sherker, A.4
Julien, J.P.5
-
193
-
-
33750532531
-
Molecular mechanisms of coupled monoubiquitination
-
Woelk T, Oldrini B, Maspero E, Confalonieri S, Cavallaro E, et al. 2006. Molecular mechanisms of coupled monoubiquitination. Nat. Cell Biol. 8: 1246-54
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 1246-1254
-
-
Woelk, T.1
Oldrini, B.2
Maspero, E.3
Confalonieri, S.4
Cavallaro, E.5
-
194
-
-
84875799835
-
Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation
-
Wu X, Johansen JV, Helin K. 2013. Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation. Mol. Cell 49: 1134-46
-
(2013)
Mol. Cell
, vol.49
, pp. 1134-1146
-
-
Wu, X.1
Johansen, J.V.2
Helin, K.3
-
195
-
-
84949992730
-
Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy
-
Wurzer B, Zaffagnini G, Fracchiolla D, Turco E, Abert C, et al. 2015. Oligomerization of p62 allows for selection of ubiquitinated cargo and isolation membrane during selective autophagy. eLife 4: e08941
-
(2015)
ELife
, vol.4
, pp. e08941
-
-
Wurzer, B.1
Zaffagnini, G.2
Fracchiolla, D.3
Turco, E.4
Abert, C.5
-
196
-
-
36348964395
-
The yeast Hex3Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation
-
Xie Y, Kerscher O, Kroetz MB, McConchie HF, Sung P, Hochstrasser M. 2007. The yeast Hex3Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. J. Biol. Chem. 282: 34176-84
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 34176-34184
-
-
Xie, Y.1
Kerscher, O.2
Kroetz, M.B.3
McConchie, H.F.4
Sung, P.5
Hochstrasser, M.6
-
197
-
-
84930678981
-
REV7 counteracts DNA double-strand break resection and affects PARP inhibition
-
Xu G, Chapman JR, Brandsma I, Yuan J, MistrikM, et al. 2015. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature 521: 541-44
-
(2015)
Nature
, vol.521
, pp. 541-544
-
-
Xu, G.1
Chapman, J.R.2
Brandsma, I.3
Yuan, J.4
Mistrik, M.5
-
198
-
-
70350015537
-
A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFand IL-1
-
Xu M, Skaug B, Zeng W, Chen ZJ. 2009. A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFand IL-1. Mol. Cell 36: 302-14
-
(2009)
Mol. Cell
, vol.36
, pp. 302-314
-
-
Xu, M.1
Skaug, B.2
Zeng, W.3
Chen, Z.J.4
-
199
-
-
2942614705
-
Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7
-
Yada M, Hatakeyama S, Kamura T, Nishiyama M, Tsunematsu R, et al. 2004. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7. EMBO J. 23: 2116-25
-
(2004)
EMBO J.
, vol.23
, pp. 2116-2125
-
-
Yada, M.1
Hatakeyama, S.2
Kamura, T.3
Nishiyama, M.4
Tsunematsu, R.5
-
200
-
-
84887453820
-
PINK1 is degraded through the N-end rule pathway
-
Yamano K, Youle RJ. 2013. PINK1 is degraded through the N-end rule pathway. Autophagy 9: 1758-69
-
(2013)
Autophagy
, vol.9
, pp. 1758-1769
-
-
Yamano, K.1
Youle, R.J.2
-
201
-
-
70349759491
-
BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response
-
Yan Q, Dutt S, Xu R, Graves K, Juszczynski P, et al. 2009. BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response. Mol. Cell 36: 110-20
-
(2009)
Mol. Cell
, vol.36
, pp. 110-120
-
-
Yan, Q.1
Dutt, S.2
Xu, R.3
Graves, K.4
Juszczynski, P.5
-
202
-
-
85026776738
-
UBE2O is a quality control factor for orphans of multiprotein complexes
-
Yanagitani K, Juszkiewicz S, Hegde RS. 2017. UBE2O is a quality control factor for orphans of multiprotein complexes. Science 357: 472-75
-
(2017)
Science
, vol.357
, pp. 472-475
-
-
Yanagitani, K.1
Juszkiewicz, S.2
Hegde, R.S.3
-
203
-
-
85042094274
-
Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system
-
Yang X, Arines FM, Zhang W, Li M. 2018. Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system. eLife 7: e33116
-
(2018)
ELife
, vol.7
, pp. e33116
-
-
Yang, X.1
Arines, F.M.2
Zhang, W.3
Li, M.4
-
204
-
-
84971236561
-
The increasing complexity of the ubiquitin code
-
Yau R, Rape M. 2016. The increasing complexity of the ubiquitin code. Nat. Cell Biol. 18: 579-86
-
(2016)
Nat. Cell Biol.
, vol.18
, pp. 579-586
-
-
Yau, R.1
Rape, M.2
-
205
-
-
85031281723
-
Assembly and function of heterotypic ubiquitin chains in cell-cycle and protein quality control
-
918-33e20
-
Yau RG, Doerner K, Castellanos ER, Haakonsen DL, Werner A, et al. 2017. Assembly and function of heterotypic ubiquitin chains in cell-cycle and protein quality control. Cell 171: 918-33. e20
-
(2017)
Cell
, vol.171
-
-
Yau, R.G.1
Doerner, K.2
Castellanos, E.R.3
Haakonsen, D.L.4
Werner, A.5
-
206
-
-
0029124883
-
Similarity of sli-1, a regulator of vulval development in C. Elegans, to the mammalian proto-oncogene c-cbl
-
Yoon CH, Lee J, Jongeward GD, Sternberg PW. 1995. Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl. Science 269: 1102-5
-
(1995)
Science
, vol.269
, pp. 1102-1105
-
-
Yoon, C.H.1
Lee, J.2
Jongeward, G.D.3
Sternberg, P.W.4
-
207
-
-
67650092919
-
LXRregulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor
-
ZelcerN, HongC, Boyadjian R, Tontonoz P. 2009. LXRregulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor. Science 325: 100-4
-
(2009)
Science
, vol.325
, pp. 100-104
-
-
Zelcer, N.1
Hong, C.2
Boyadjian, R.3
Tontonoz, P.4
-
208
-
-
84855764312
-
Cysteine methylation disrupts ubiquitin-chain sensing in NF-B activation
-
Zhang L, Ding X, Cui J, Xu H, Chen J, et al. 2011. Cysteine methylation disrupts ubiquitin-chain sensing in NF-B activation. Nature 481: 204-8
-
(2011)
Nature
, vol.481
, pp. 204-208
-
-
Zhang, L.1
Ding, X.2
Cui, J.3
Xu, H.4
Chen, J.5
-
209
-
-
84906898355
-
Coordinated regulation of protein synthesis and degradation by mTORC1
-
Zhang Y, Nicholatos J, Dreier JR, Ricoult SJ, Widenmaier SB, et al. 2014. Coordinated regulation of protein synthesis and degradation by mTORC1. Nature 513: 440-43
-
(2014)
Nature
, vol.513
, pp. 440-443
-
-
Zhang, Y.1
Nicholatos, J.2
Dreier, J.R.3
Ricoult, S.J.4
Widenmaier, S.B.5
-
210
-
-
84881150929
-
Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER
-
Zhang ZR, Bonifacino JS, Hegde RS. 2013. Deubiquitinases sharpen substrate discrimination during membrane protein degradation from the ER. Cell 154: 609-22
-
(2013)
Cell
, vol.154
, pp. 609-622
-
-
Zhang, Z.R.1
Bonifacino, J.S.2
Hegde, R.S.3
-
211
-
-
84903124095
-
Crosstalk between ubiquitin and other posttranslational modifications on chromatin during double-strand break repair
-
Zhao Y, Brickner JR, Majid MC, Mosammaparast N. 2014. Crosstalk between ubiquitin and other posttranslational modifications on chromatin during double-strand break repair. Trends Cell Biol. 24: 426-34
-
(2014)
Trends Cell Biol.
, vol.24
, pp. 426-434
-
-
Zhao, Y.1
Brickner, J.R.2
Majid, M.C.3
Mosammaparast, N.4
-
212
-
-
85027172280
-
ESCRTs function directly on the lysosomemembrane to downregulate ubiquitinated lysosomal membrane proteins
-
Zhu L, Jorgensen JR, LiM, Chuang YS, Emr SD. 2017. ESCRTs function directly on the lysosomemembrane to downregulate ubiquitinated lysosomal membrane proteins. eLife 6: e26403
-
(2017)
ELife
, vol.6
, pp. e26403
-
-
Zhu, L.1
Jorgensen, J.R.2
Li, M.3
Chuang, Y.S.4
Emr, S.D.5
|