Biochemistry: Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase

Science

Volumn 309, Issue 5731, 2005, Pages 127-130

  Cadwell, Ken ^a   Coscoy, Laurent ^a  

^a 142 Life Sciences ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; CELL CULTURE; CHEMICAL BONDS; CYTOLOGY; ENZYMES; SUBSTRATES; VIRUSES;

CELLULAR FUNCTION; E3 ENZYMES (E3); ISOPEPTIDES; LIGASES;

BIOCHEMISTRY;

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MERCAPTOETHANOL; PROTEIN MIR1; PROTEIN MIR2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CYSTEINE; HLA B7 ANTIGEN; LYSINE; MIR1 E3 UBIQUITIN LIGASE, KSHV; SERINE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

BIOCHEMISTRY;

AMINO TERMINAL SEQUENCE; ARTICLE; DOWN REGULATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; INTERNALIZATION; MAJOR HISTOCOMPATIBILITY COMPLEX; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; REGULATORY MECHANISM; UBIQUITINATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CHEMISTRY; CHO CELL; ENDOCYTOSIS; ENZYMOLOGY; GENETIC TRANSDUCTION; GENETICS; HAMSTER; HUMAN; HUMAN HERPESVIRUS 8; METABOLISM; MUTATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE;

KAPOSI SARCOMA ASSOCIATED HERPESVIRUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CHO CELLS; CRICETINAE; CYSTEINE; DOWN-REGULATION; ENDOCYTOSIS; HERPESVIRUS 8, HUMAN; HLA-B7 ANTIGEN; HUMANS; LYSINE; MUTATION; PROTEIN STRUCTURE, TERTIARY; SERINE; TRANSDUCTION, GENETIC; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 21744433861     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1110340     Document Type: Article

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16. We thank N. Jarousse, M. Schlissel, and N. Shastri for helpful discussions and critical reading of the manuscript This work has been supported by the PEW scholars program in the biological sciences, the Hellman family, and a grant (1R01CA108447-01) from the National Cancer Institute.