SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling

Molecular Cell

Volumn 63, Issue 6, 2016, Pages 990-1005

  Elliott, Paul R ^a   Leske, Derek ^b   Hrdinka, Matous ^b   Bagola, Katrin ^b   Fiil, Berthe K ^b   McLaughlin, Stephen H ^a   Wagstaff, Jane ^a   Volkmar, Norbert ^b   Christianson, John C ^b   Kessler, Benedikt M ^b   Freund, Stefan M V ^a   Komander, David ^a   Gyrd Hansen, Mads ^b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DEUBIQUITINASE; DEUBIQUITINASE CYLD; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINEAR UBIQUITIN CHAIN ASSEMBLY COMPLEX; PROTEIN; SPERMATOGENESIS ASSOCIATED PROTEIN 2; TUMOR NECROSIS FACTOR RECEPTOR 1; UBIQUITIN; UNCLASSIFIED DRUG; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CYLD PROTEIN, HUMAN; GUMBY PROTEIN, HUMAN; NOD2 PROTEIN, HUMAN; PROTEIN BINDING; PROTEINASE; RECOMBINANT PROTEIN; RNF31 PROTEIN, HUMAN; SPATA2 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CATALYST; ENZYME ACTIVATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN HYDROLYSIS; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; AMINO ACID SEQUENCE; BINDING SITE; CHEMISTRY; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; INNATE IMMUNITY; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR DOCKING; PROTEIN SECONDARY STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ENDOPEPTIDASES; ESCHERICHIA COLI; GENE EXPRESSION; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; KINETICS; MOLECULAR DOCKING SIMULATION; NF-KAPPA B; NOD2 SIGNALING ADAPTOR PROTEIN; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, SECONDARY; PROTEINS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84991672335     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.08.001     Document Type: Article

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