-
1
-
-
1442323729
-
N-terminal ubiquitination: more protein substrates join in.
-
Ciechanover A, Ben Saadon R. N-terminal ubiquitination: more protein substrates join in. Trends Cell Biol 2004;14:103-106.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 103-106
-
-
Ciechanover, A.1
Ben Saadon, R.2
-
2
-
-
70350461507
-
Building ubiquitin chains: E2 enzymes at work.
-
Ye Y, Rape M. Building ubiquitin chains: E2 enzymes at work. Nat Rev Mol Cell Biol 2009;10:755-764.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 755-764
-
-
Ye, Y.1
Rape, M.2
-
4
-
-
79551493745
-
E2s: structurally economical and functionally replete.
-
Wenzel DM, Stoll KE, Klevit RE. E2s: structurally economical and functionally replete. Biochem J 2010;433:31-42.
-
(2010)
Biochem J
, vol.433
, pp. 31-42
-
-
Wenzel, D.M.1
Stoll, K.E.2
Klevit, R.E.3
-
5
-
-
0037213013
-
PHD domains and E3 ubiquitin ligases: viruses make the connection.
-
Coscoy L, Ganem D. PHD domains and E3 ubiquitin ligases: viruses make the connection. Trends Cell Biol 2003;13:7-12.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 7-12
-
-
Coscoy, L.1
Ganem, D.2
-
6
-
-
0036851310
-
Identification of new herpesvirus gene homologs in the human genome.
-
Holzerlandt R, Orengo C, Kellam P, Alba MM. Identification of new herpesvirus gene homologs in the human genome. Genome Res 2002;12:1739-1748.
-
(2002)
Genome Res
, vol.12
, pp. 1739-1748
-
-
Holzerlandt, R.1
Orengo, C.2
Kellam, P.3
Alba, M.M.4
-
7
-
-
0038352134
-
c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity.
-
Goto E, Ishido S, Sato Y, Ohgimoto S, Ohgimoto K, Nagano-Fujii M, Hotta H. c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity. J Biol Chem 2003;278:14657-14668.
-
(2003)
J Biol Chem
, vol.278
, pp. 14657-14668
-
-
Goto, E.1
Ishido, S.2
Sato, Y.3
Ohgimoto, S.4
Ohgimoto, K.5
Nagano-Fujii, M.6
Hotta, H.7
-
8
-
-
0346373729
-
Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.
-
Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Fruh K. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J Virol 2004;78:1109-1120.
-
(2004)
J Virol
, vol.78
, pp. 1109-1120
-
-
Bartee, E.1
Mansouri, M.2
Hovey Nerenberg, B.T.3
Gouveia, K.4
Fruh, K.5
-
9
-
-
26244468727
-
Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases.
-
Lehner PJ, Hoer S, Dodd R, Duncan LM. Downregulation of cell surface receptors by the K3 family of viral and cellular ubiquitin E3 ligases. Immunol Rev 2005;207:112-125.
-
(2005)
Immunol Rev
, vol.207
, pp. 112-125
-
-
Lehner, P.J.1
Hoer, S.2
Dodd, R.3
Duncan, L.M.4
-
10
-
-
33750369258
-
A novel family of membrane-bound E3 ubiquitin ligases.
-
Ohmura-Hoshino M, Goto E, Matsuki Y, Aoki M, Mito M, Uematsu M, Hotta H, Ishido S. A novel family of membrane-bound E3 ubiquitin ligases. J Biochem 2006;140:147-154.
-
(2006)
J Biochem
, vol.140
, pp. 147-154
-
-
Ohmura-Hoshino, M.1
Goto, E.2
Matsuki, Y.3
Aoki, M.4
Mito, M.5
Uematsu, M.6
Hotta, H.7
Ishido, S.8
-
11
-
-
0035945349
-
A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition.
-
Coscoy L, Sanchez DJ, Ganem D. A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition. J Cell Biol 2001;155:1265-1273.
-
(2001)
J Cell Biol
, vol.155
, pp. 1265-1273
-
-
Coscoy, L.1
Sanchez, D.J.2
Ganem, D.3
-
12
-
-
0037093467
-
Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation.
-
Hewitt EW, Duncan L, Mufti D, Baker J, Stevenson PG, Lehner PJ. Ubiquitylation of MHC class I by the K3 viral protein signals internalization and TSG101-dependent degradation. EMBO J 2002;21:2418-2429.
-
(2002)
EMBO J
, vol.21
, pp. 2418-2429
-
-
Hewitt, E.W.1
Duncan, L.2
Mufti, D.3
Baker, J.4
Stevenson, P.G.5
Lehner, P.J.6
-
13
-
-
21744433861
-
Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase.
-
Cadwell K, Coscoy L. Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase. Science 2005;309:127-130.
-
(2005)
Science
, vol.309
, pp. 127-130
-
-
Cadwell, K.1
Coscoy, L.2
-
14
-
-
34249042608
-
Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3.
-
Wang X, Herr RA, Chua WJ, Lybarger L, Wiertz EJ, Hansen TH. Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3. J Cell Biol 2007;177:613-624.
-
(2007)
J Cell Biol
, vol.177
, pp. 613-624
-
-
Wang, X.1
Herr, R.A.2
Chua, W.J.3
Lybarger, L.4
Wiertz, E.J.5
Hansen, T.H.6
-
15
-
-
74049086778
-
Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates.
-
Wang X, Herr RA, Rabelink M, Hoeben RC, Wiertz EJ, Hansen TH. Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates. J Cell Biol 2009;187:655-668.
-
(2009)
J Cell Biol
, vol.187
, pp. 655-668
-
-
Wang, X.1
Herr, R.A.2
Rabelink, M.3
Hoeben, R.C.4
Wiertz, E.J.5
Hansen, T.H.6
-
16
-
-
0019000271
-
Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis.
-
Hershko A, Ciechanover A, Heller H, Haas AL, Rose IA. Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis. Proc Natl Acad Sci U S A 1980;77:1783-1786.
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, pp. 1783-1786
-
-
Hershko, A.1
Ciechanover, A.2
Heller, H.3
Haas, A.L.4
Rose, I.A.5
-
17
-
-
0041706156
-
A proteomics approach to understanding protein ubiquitination.
-
Peng JM, Schwartz D, Elias JE, Thoreen CC, Cheng DM, Marsischky G, Roelofs J, Finley D, Gygi SP. A proteomics approach to understanding protein ubiquitination. Nat Biotechnol 2003;21:921-926.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 921-926
-
-
Peng, J.M.1
Schwartz, D.2
Elias, J.E.3
Thoreen, C.C.4
Cheng, D.M.5
Marsischky, G.6
Roelofs, J.7
Finley, D.8
Gygi, S.P.9
-
18
-
-
23144452492
-
Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics.
-
Kirkpatrick DS, Denison C, Gygi SP. Weighing in on ubiquitin: the expanding role of mass-spectrometry-based proteomics. Nat Cell Biol 2005;7:750-757.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 750-757
-
-
Kirkpatrick, D.S.1
Denison, C.2
Gygi, S.P.3
-
19
-
-
78650253267
-
Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids.
-
Shimizu Y, Okuda-Shimizu Y, Hendershot LM. Ubiquitylation of an ERAD substrate occurs on multiple types of amino acids. Mol Cell 2010;40:917-926.
-
(2010)
Mol Cell
, vol.40
, pp. 917-926
-
-
Shimizu, Y.1
Okuda-Shimizu, Y.2
Hendershot, L.M.3
-
20
-
-
38049059937
-
Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.
-
Tait SW, de Vries E, Maas C, Keller AM, D'Santos CS, Borst J. Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment. J Cell Biol 2007;179:1453-1466.
-
(2007)
J Cell Biol
, vol.179
, pp. 1453-1466
-
-
Tait, S.W.1
de Vries, E.2
Maas, C.3
Keller, A.M.4
D'Santos, C.S.5
Borst, J.6
-
21
-
-
78650038839
-
Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu.
-
Tokarev AA, Munguia J, Guatelli JC. Serine-threonine ubiquitination mediates downregulation of BST-2/tetherin and relief of restricted virion release by HIV-1 Vpu. J Virol 2011;85:51-63.
-
(2011)
J Virol
, vol.85
, pp. 51-63
-
-
Tokarev, A.A.1
Munguia, J.2
Guatelli, J.C.3
-
22
-
-
35748954927
-
Ubiquitination of mammalian Pex5p, the peroxisomal import receptor.
-
Carvalho AF, Pinto MP, Grou CP, Alencastre IS, Fransen M, Sa-Miranda C, Azevedo JE. Ubiquitination of mammalian Pex5p, the peroxisomal import receptor. J Biol Chem 2007;282:31267-31272.
-
(2007)
J Biol Chem
, vol.282
, pp. 31267-31272
-
-
Carvalho, A.F.1
Pinto, M.P.2
Grou, C.P.3
Alencastre, I.S.4
Fransen, M.5
Sa-Miranda, C.6
Azevedo, J.E.7
-
23
-
-
34547957271
-
A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p.
-
Williams C, van den BM, Sprenger RR, Distel B. A conserved cysteine is essential for Pex4p-dependent ubiquitination of the peroxisomal import receptor Pex5p. J Biol Chem 2007;282:22534-22543.
-
(2007)
J Biol Chem
, vol.282
, pp. 22534-22543
-
-
Williams, C.1
van den, B.M.2
Sprenger, R.R.3
Distel, B.4
-
24
-
-
79960172953
-
Cysteine Ubiquitination of PTS1 Receptor Pex5p Regulates Pex5p Recycling.
-
Okumoto K, Misono S, Miyata N, Matsumoto Y, Mukai S, Fujiki Y. Cysteine Ubiquitination of PTS1 Receptor Pex5p Regulates Pex5p Recycling. Traffic 2011;12:1067-1083.
-
(2011)
Traffic
, vol.12
, pp. 1067-1083
-
-
Okumoto, K.1
Misono, S.2
Miyata, N.3
Matsumoto, Y.4
Mukai, S.5
Fujiki, Y.6
-
25
-
-
9444290733
-
Ubiquitination of the peroxisomal import receptor Pex5p.
-
Platta HW, Girzalsky W, Erdmann R. Ubiquitination of the peroxisomal import receptor Pex5p. Biochem J 2004;384:37-45.
-
(2004)
Biochem J
, vol.384
, pp. 37-45
-
-
Platta, H.W.1
Girzalsky, W.2
Erdmann, R.3
-
26
-
-
12544259938
-
Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import.
-
Kiel JA, Emmrich K, Meyer HE, Kunau WH. Ubiquitination of the peroxisomal targeting signal type 1 receptor, Pex5p, suggests the presence of a quality control mechanism during peroxisomal matrix protein import. J Biol Chem 2005;280:1921-1930.
-
(2005)
J Biol Chem
, vol.280
, pp. 1921-1930
-
-
Kiel, J.A.1
Emmrich, K.2
Meyer, H.E.3
Kunau, W.H.4
-
27
-
-
14844311942
-
The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells.
-
Kragt A, Voorn-Brouwer T, van den BM, Distel B. The Saccharomyces cerevisiae peroxisomal import receptor Pex5p is monoubiquitinated in wild type cells. J Biol Chem 2005;280:7867-7874.
-
(2005)
J Biol Chem
, vol.280
, pp. 7867-7874
-
-
Kragt, A.1
Voorn-Brouwer, T.2
van den, B.M.3
Distel, B.4
-
28
-
-
49449096720
-
Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p.
-
Williams C, van den BM, Geers E, Distel B. Pex10p functions as an E3 ligase for the Ubc4p-dependent ubiquitination of Pex5p. Biochem Biophys Res Commun 2008;374:620-624.
-
(2008)
Biochem Biophys Res Commun
, vol.374
, pp. 620-624
-
-
Williams, C.1
van den, B.M.2
Geers, E.3
Distel, B.4
-
29
-
-
70350447348
-
Pex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import.
-
Platta HW, El Magraoui F, Baumer BE, Schlee D, Girzalsky W, Erdmann R. Pex2 and pex12 function as protein-ubiquitin ligases in peroxisomal protein import. Mol Cell Biol 2009;29:5505-5516.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5505-5516
-
-
Platta, H.W.1
El Magraoui, F.2
Baumer, B.E.3
Schlee, D.4
Girzalsky, W.5
Erdmann, R.6
-
30
-
-
39449102122
-
The AAA peroxins Pex1p and Pex6p function as dislocases for the ubiquitinated peroxisomal import receptor Pex5p.
-
Platta HW, Debelyy MO, El Magraoui F, Erdmann R. The AAA peroxins Pex1p and Pex6p function as dislocases for the ubiquitinated peroxisomal import receptor Pex5p. Biochem Soc Trans 2008;36:99-104.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 99-104
-
-
Platta, H.W.1
Debelyy, M.O.2
El Magraoui, F.3
Erdmann, R.4
-
31
-
-
0023749075
-
Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins.
-
Lippincott-Schwartz J, Bonifacino JS, Yuan LC, Klausner RD. Degradation from the endoplasmic reticulum: disposing of newly synthesized proteins. Cell 1988;54:209-220.
-
(1988)
Cell
, vol.54
, pp. 209-220
-
-
Lippincott-Schwartz, J.1
Bonifacino, J.S.2
Yuan, L.C.3
Klausner, R.D.4
-
32
-
-
0024345717
-
Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly.
-
Bonifacino JS, Suzuki CK, Lippincott-Schwartz J, Weissman AM, Klausner RD. Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly. J Cell Biol 1989;109:73-83.
-
(1989)
J Cell Biol
, vol.109
, pp. 73-83
-
-
Bonifacino, J.S.1
Suzuki, C.K.2
Lippincott-Schwartz, J.3
Weissman, A.M.4
Klausner, R.D.5
-
33
-
-
0033601349
-
The role of multiubiquitination in dislocation and degradation of the alpha subunit of the T cell antigen receptor.
-
Yu H, Kopito RR. The role of multiubiquitination in dislocation and degradation of the alpha subunit of the T cell antigen receptor. J Biol Chem 1999;274:36852-36858.
-
(1999)
J Biol Chem
, vol.274
, pp. 36852-36858
-
-
Yu, H.1
Kopito, R.R.2
-
34
-
-
77954904488
-
Serine residues in the cytosolic tail of the T-cell antigen receptor alpha-chain mediate ubiquitination and endoplasmic reticulum-associated degradation of the unassembled protein.
-
Ishikura S, Weissman AM, Bonifacino JS. Serine residues in the cytosolic tail of the T-cell antigen receptor alpha-chain mediate ubiquitination and endoplasmic reticulum-associated degradation of the unassembled protein. J Biol Chem 2010;285:23916-23924.
-
(2010)
J Biol Chem
, vol.285
, pp. 23916-23924
-
-
Ishikura, S.1
Weissman, A.M.2
Bonifacino, J.S.3
-
35
-
-
77954047969
-
Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps.
-
Magadan JG, Perez-Victoria FJ, Sougrat R, Ye Y, Strebel K, Bonifacino JS. Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps. PLoS Pathog 2010;6:e1000869.
-
(2010)
PLoS Pathog
, vol.6
-
-
Magadan, J.G.1
Perez-Victoria, F.J.2
Sougrat, R.3
Ye, Y.4
Strebel, K.5
Bonifacino, J.S.6
-
36
-
-
36249022750
-
Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp.
-
Okuda-Shimizu Y, Hendershot LM. Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp. Mol Cell 2007;28:544-554.
-
(2007)
Mol Cell
, vol.28
, pp. 544-554
-
-
Okuda-Shimizu, Y.1
Hendershot, L.M.2
-
37
-
-
0035144199
-
Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.
-
Bays NW, Gardner RG, Seelig LP, Joazeiro CA, Hampton RY. Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation. Nat Cell Biol 2001;3:24-29.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 24-29
-
-
Bays, N.W.1
Gardner, R.G.2
Seelig, L.P.3
Joazeiro, C.A.4
Hampton, R.Y.5
-
38
-
-
0035815754
-
Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation.
-
Deak PM, Wolf DH. Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation. J Biol Chem 2001;276:10663-10669.
-
(2001)
J Biol Chem
, vol.276
, pp. 10663-10669
-
-
Deak, P.M.1
Wolf, D.H.2
-
39
-
-
0037021416
-
Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation.
-
Kaneko M, Ishiguro M, Niinuma Y, Uesugi M, Nomura Y. Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation. FEBS Lett 2002;532:147-152.
-
(2002)
FEBS Lett
, vol.532
, pp. 147-152
-
-
Kaneko, M.1
Ishiguro, M.2
Niinuma, Y.3
Uesugi, M.4
Nomura, Y.5
-
40
-
-
0037470838
-
A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1.
-
Nadav E, Shmueli A, Barr H, Gonen H, Ciechanover A, Reiss Y. A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1. Biochem Biophys Res Commun 2003;303:91-97.
-
(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 91-97
-
-
Nadav, E.1
Shmueli, A.2
Barr, H.3
Gonen, H.4
Ciechanover, A.5
Reiss, Y.6
-
41
-
-
47249159844
-
Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor.
-
Grou CP, Carvalho AF, Pinto MP, Wiese S, Piechura H, Meyer HE, Warscheid B, Sa-Miranda C, Azevedo JE. Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor. J Biol Chem 2008;283:14190-14197.
-
(2008)
J Biol Chem
, vol.283
, pp. 14190-14197
-
-
Grou, C.P.1
Carvalho, A.F.2
Pinto, M.P.3
Wiese, S.4
Piechura, H.5
Meyer, H.E.6
Warscheid, B.7
Sa-Miranda, C.8
Azevedo, J.E.9
-
42
-
-
0028607435
-
Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53.
-
Scheffner M, Huibregtse JM, Howley PM. Identification of a human ubiquitin-conjugating enzyme that mediates the E6-AP-dependent ubiquitination of p53. Proc Natl Acad Sci U S A 1994;91:8797-8801.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 8797-8801
-
-
Scheffner, M.1
Huibregtse, J.M.2
Howley, P.M.3
-
43
-
-
27644499059
-
Expression, purification, and properties of the Ubc4/5 family of E2 enzymes.
-
Lorick KL, Jensen JP, Weissman AM. Expression, purification, and properties of the Ubc4/5 family of E2 enzymes. Methods Enzymol 2005;398:54-68.
-
(2005)
Methods Enzymol
, vol.398
, pp. 54-68
-
-
Lorick, K.L.1
Jensen, J.P.2
Weissman, A.M.3
-
44
-
-
68549119002
-
Role of the RING-CH domain of viral ligase mK3 in ubiquitination of non-lysine and lysine MHC I residues.
-
Herr RA, Harris J, Fang S, Wang X, Hansen TH. Role of the RING-CH domain of viral ligase mK3 in ubiquitination of non-lysine and lysine MHC I residues. Traffic 2009;10:1301-1317.
-
(2009)
Traffic
, vol.10
, pp. 1301-1317
-
-
Herr, R.A.1
Harris, J.2
Fang, S.3
Wang, X.4
Hansen, T.H.5
-
45
-
-
41949129137
-
The specificities of Kaposi's sarcoma-associated herpesvirus-encoded E3 ubiquitin ligases are determined by the positions of lysine or cysteine residues within the intracytoplasmic domains of their targets.
-
Cadwell K, Coscoy L. The specificities of Kaposi's sarcoma-associated herpesvirus-encoded E3 ubiquitin ligases are determined by the positions of lysine or cysteine residues within the intracytoplasmic domains of their targets. J Virol 2008;82:4184-4189.
-
(2008)
J Virol
, vol.82
, pp. 4184-4189
-
-
Cadwell, K.1
Coscoy, L.2
-
46
-
-
0034676443
-
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
-
Schulman BA, Carrano AC, Jeffrey PD, Bowen Z, Kinnucan ER, Finnin MS, Elledge SJ, Harper JW, Pagano M, Pavletich NP. Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature 2000;408:381-386.
-
(2000)
Nature
, vol.408
, pp. 381-386
-
-
Schulman, B.A.1
Carrano, A.C.2
Jeffrey, P.D.3
Bowen, Z.4
Kinnucan, E.R.5
Finnin, M.S.6
Elledge, S.J.7
Harper, J.W.8
Pagano, M.9
Pavletich, N.P.10
-
47
-
-
0034682718
-
Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases.
-
Zheng N, Wang P, Jeffrey PD, Pavletich NP. Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases. Cell 2000;102:533-539.
-
(2000)
Cell
, vol.102
, pp. 533-539
-
-
Zheng, N.1
Wang, P.2
Jeffrey, P.D.3
Pavletich, N.P.4
-
48
-
-
18344391432
-
Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
-
Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Paveltich NP. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature 2002;416:703-709.
-
(2002)
Nature
, vol.416
, pp. 703-709
-
-
Zheng, N.1
Schulman, B.A.2
Song, L.3
Miller, J.J.4
Jeffrey, P.D.5
Wang, P.6
Chu, C.7
Koepp, D.M.8
Elledge, S.J.9
Pagano, M.10
Conaway, R.C.11
Conaway, J.W.12
Harper, J.W.13
Paveltich, N.P.14
-
49
-
-
0141753130
-
A conserved catalytic residue in the ubiquitin-conjugating enzyme family.
-
Wu PY, Hanlon M, Eddins M, Tsui C, Rogers RS, Jensen JP, Matunis MJ, Weissman AM, Wolberger C, Pickart CM. A conserved catalytic residue in the ubiquitin-conjugating enzyme family. EMBO J 2003;22:5241-5250.
-
(2003)
EMBO J
, vol.22
, pp. 5241-5250
-
-
Wu, P.Y.1
Hanlon, M.2
Eddins, M.3
Tsui, C.4
Rogers, R.S.5
Jensen, J.P.6
Matunis, M.J.7
Weissman, A.M.8
Wolberger, C.9
Pickart, C.M.10
-
50
-
-
30044437590
-
Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases.
-
Ozkan E, Yu H, Deisenhofer J. Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases. Proc Natl Acad Sci U S A 2005;102:18890-18895.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18890-18895
-
-
Ozkan, E.1
Yu, H.2
Deisenhofer, J.3
-
51
-
-
27644451320
-
Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection.
-
Wang W, Nacusi L, Sheaff RJ, Liu X. Ubiquitination of p21Cip1/WAF1 by SCFSkp2: substrate requirement and ubiquitination site selection. Biochemistry 2005;44:14553-14564.
-
(2005)
Biochemistry
, vol.44
, pp. 14553-14564
-
-
Wang, W.1
Nacusi, L.2
Sheaff, R.J.3
Liu, X.4
-
52
-
-
79957949190
-
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids.
-
Wenzel DM, Lissounov A, Brzovic PS, Klevit RE. UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids. Nature 2011;474:105-108.
-
(2011)
Nature
, vol.474
, pp. 105-108
-
-
Wenzel, D.M.1
Lissounov, A.2
Brzovic, P.S.3
Klevit, R.E.4
-
53
-
-
33745742269
-
Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology.
-
Kirkpatrick DS, Hathaway NA, Hanna J, Elsasser S, Rush J, Finley D, King RW, Gygi SP. Quantitative analysis of in vitro ubiquitinated cyclin B1 reveals complex chain topology. Nat Cell Biol 2006;8:700-710.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 700-710
-
-
Kirkpatrick, D.S.1
Hathaway, N.A.2
Hanna, J.3
Elsasser, S.4
Rush, J.5
Finley, D.6
King, R.W.7
Gygi, S.P.8
-
54
-
-
34447097834
-
Sequential E2s drive polyubiquitin chain assembly on APC targets.
-
Rodrigo-Brenni MC, Morgan DO. Sequential E2s drive polyubiquitin chain assembly on APC targets. Cell 2007;130:127-139.
-
(2007)
Cell
, vol.130
, pp. 127-139
-
-
Rodrigo-Brenni, M.C.1
Morgan, D.O.2
-
55
-
-
33947243954
-
A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate.
-
Li W, Tu D, Brunger AT, Ye Y. A ubiquitin ligase transfers preformed polyubiquitin chains from a conjugating enzyme to a substrate. Nature 2007;446:333-337.
-
(2007)
Nature
, vol.446
, pp. 333-337
-
-
Li, W.1
Tu, D.2
Brunger, A.T.3
Ye, Y.4
-
56
-
-
33646122226
-
Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase.
-
Wang M, Cheng D, Peng J, Pickart CM. Molecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase. EMBO J 2006;25:1710-1719.
-
(2006)
EMBO J
, vol.25
, pp. 1710-1719
-
-
Wang, M.1
Cheng, D.2
Peng, J.3
Pickart, C.M.4
-
57
-
-
43049162227
-
Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex.
-
Jin L, Williamson A, Banerjee S, Philipp I, Rape M. Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. Cell 2008;133:653-665.
-
(2008)
Cell
, vol.133
, pp. 653-665
-
-
Jin, L.1
Williamson, A.2
Banerjee, S.3
Philipp, I.4
Rape, M.5
-
58
-
-
77955990685
-
Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin.
-
Rodrigo-Brenni MC, Foster SA, Morgan DO. Catalysis of lysine 48-specific ubiquitin chain assembly by residues in E2 and ubiquitin. Mol Cell 2010;39:548-559.
-
(2010)
Mol Cell
, vol.39
, pp. 548-559
-
-
Rodrigo-Brenni, M.C.1
Foster, S.A.2
Morgan, D.O.3
-
59
-
-
33646147146
-
Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules.
-
Duncan LM, Piper S, Dodd RB, Saville MK, Sanderson CM, Luzio J, Lehner PJ. Lysine-63-linked ubiquitination is required for endolysosomal degradation of class I molecules. EMBO J 2006;25:1635-1645.
-
(2006)
EMBO J
, vol.25
, pp. 1635-1645
-
-
Duncan, L.M.1
Piper, S.2
Dodd, R.B.3
Saville, M.K.4
Sanderson, C.M.5
Luzio, J.6
Lehner, P.J.7
-
60
-
-
34948848684
-
E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages.
-
Christensen DE, Brzovic PS, Klevit RE. E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages. Nat Struct Mol Biol 2007;14:941-948.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 941-948
-
-
Christensen, D.E.1
Brzovic, P.S.2
Klevit, R.E.3
-
61
-
-
77949548466
-
Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate.
-
Wu K, Kovacev J, Pan ZQ. Priming and extending: a UbcH5/Cdc34 E2 handoff mechanism for polyubiquitination on a SCF substrate. Mol Cell 2010;37:784-796.
-
(2010)
Mol Cell
, vol.37
, pp. 784-796
-
-
Wu, K.1
Kovacev, J.2
Pan, Z.Q.3
-
62
-
-
0030886889
-
Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells.
-
Hazes B, Read RJ. Accumulating evidence suggests that several AB-toxins subvert the endoplasmic reticulum-associated protein degradation pathway to enter target cells. Biochemistry 1997;36:11051-11054.
-
(1997)
Biochemistry
, vol.36
, pp. 11051-11054
-
-
Hazes, B.1
Read, R.J.2
|