-
1
-
-
79954422997
-
Chaperone-mediated autophagy in protein quality control
-
Arias E., Cuervo A.M. Chaperone-mediated autophagy in protein quality control. Curr. Opin. Cell Biol. 2011, 23:184-189.
-
(2011)
Curr. Opin. Cell Biol.
, vol.23
, pp. 184-189
-
-
Arias, E.1
Cuervo, A.M.2
-
2
-
-
77954237882
-
Network organization of the human autophagy system
-
Behrends C., Sowa M.E., Gygi S.P., Harper J.W. Network organization of the human autophagy system. Nature 2010, 466:68-76.
-
(2010)
Nature
, vol.466
, pp. 68-76
-
-
Behrends, C.1
Sowa, M.E.2
Gygi, S.P.3
Harper, J.W.4
-
3
-
-
84877341621
-
Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis
-
Benato F., Skobo T., Gioacchini G., Moro I., Ciccosanti F., Piacentini M., Fimia G.M., Carnevali O., Dalla Valle L. Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis. Autophagy 2013, 9:476-495.
-
(2013)
Autophagy
, vol.9
, pp. 476-495
-
-
Benato, F.1
Skobo, T.2
Gioacchini, G.3
Moro, I.4
Ciccosanti, F.5
Piacentini, M.6
Fimia, G.M.7
Carnevali, O.8
Dalla Valle, L.9
-
4
-
-
33645216339
-
Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome
-
Bondar T., Kalinina A., Khair L., Kopanja D., Nag A., Bagchi S., Raychaudhuri P. Cul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosome. Mol. Cell. Biol. 2006, 26:2531-2539.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2531-2539
-
-
Bondar, T.1
Kalinina, A.2
Khair, L.3
Kopanja, D.4
Nag, A.5
Bagchi, S.6
Raychaudhuri, P.7
-
5
-
-
45449116322
-
The involvement of cell death and survival in neural tube defects: a distinct role for apoptosis and autophagy?
-
Cecconi F., Piacentini M., Fimia G.M. The involvement of cell death and survival in neural tube defects: a distinct role for apoptosis and autophagy?. Cell Death Differ. 2008, 15:1170-1177.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 1170-1177
-
-
Cecconi, F.1
Piacentini, M.2
Fimia, G.M.3
-
7
-
-
77957728513
-
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy
-
Di Bartolomeo S., Corazzari M., Nazio F., Oliverio S., Lisi G., Antonioli M., Pagliarini V., Matteoni S., Fuoco C., Giunta L., et al. The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy. J.Cell Biol. 2010, 191:155-168.
-
(2010)
J.Cell Biol.
, vol.191
, pp. 155-168
-
-
Di Bartolomeo, S.1
Corazzari, M.2
Nazio, F.3
Oliverio, S.4
Lisi, G.5
Antonioli, M.6
Pagliarini, V.7
Matteoni, S.8
Fuoco, C.9
Giunta, L.10
-
8
-
-
81855228182
-
MTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR
-
Duan S., Skaar J.R., Kuchay S., Toschi A., Kanarek N., Ben-Neriah Y., Pagano M. mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR. Mol. Cell 2011, 44:317-324.
-
(2011)
Mol. Cell
, vol.44
, pp. 317-324
-
-
Duan, S.1
Skaar, J.R.2
Kuchay, S.3
Toschi, A.4
Kanarek, N.5
Ben-Neriah, Y.6
Pagano, M.7
-
9
-
-
79953068658
-
Structural regulation of cullin-RING ubiquitin ligase complexes
-
Duda D.M., Scott D.C., Calabrese M.F., Zimmerman E.S., Zheng N., Schulman B.A. Structural regulation of cullin-RING ubiquitin ligase complexes. Curr. Opin. Struct. Biol. 2011, 21:257-264.
-
(2011)
Curr. Opin. Struct. Biol.
, vol.21
, pp. 257-264
-
-
Duda, D.M.1
Scott, D.C.2
Calabrese, M.F.3
Zimmerman, E.S.4
Zheng, N.5
Schulman, B.A.6
-
10
-
-
80054694510
-
Global identification of modular cullin-RING ligase substrates
-
Emanuele M.J., Elia A.E., Xu Q., Thoma C.R., Izhar L., Leng Y., Guo A., Chen Y.N., Rush J., Hsu P.W., et al. Global identification of modular cullin-RING ligase substrates. Cell 2011, 147:459-474.
-
(2011)
Cell
, vol.147
, pp. 459-474
-
-
Emanuele, M.J.1
Elia, A.E.2
Xu, Q.3
Thoma, C.R.4
Izhar, L.5
Leng, Y.6
Guo, A.7
Chen, Y.N.8
Rush, J.9
Hsu, P.W.10
-
11
-
-
77951911179
-
Regulation of autophagy in mammals and its interplay with apoptosis
-
Fimia G.M., Piacentini M. Regulation of autophagy in mammals and its interplay with apoptosis. Cell. Mol. Life Sci. 2010, 67:1581-1588.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 1581-1588
-
-
Fimia, G.M.1
Piacentini, M.2
-
12
-
-
34347344990
-
Ambra1 regulates autophagy and development of the nervous system
-
Fimia G.M., Stoykova A., Romagnoli A., Giunta L., Di Bartolomeo S., Nardacci R., Corazzari M., Fuoco C., Ucar A., Schwartz P., et al. Ambra1 regulates autophagy and development of the nervous system. Nature 2007, 447:1121-1125.
-
(2007)
Nature
, vol.447
, pp. 1121-1125
-
-
Fimia, G.M.1
Stoykova, A.2
Romagnoli, A.3
Giunta, L.4
Di Bartolomeo, S.5
Nardacci, R.6
Corazzari, M.7
Fuoco, C.8
Ucar, A.9
Schwartz, P.10
-
13
-
-
84880302335
-
Ambra1 at the crossroad between autophagy and cell death
-
Fimia G.M., Corazzari M., Antonioli M., Piacentini M. Ambra1 at the crossroad between autophagy and cell death. Oncogene 2013, 32:3311-3318.
-
(2013)
Oncogene
, vol.32
, pp. 3311-3318
-
-
Fimia, G.M.1
Corazzari, M.2
Antonioli, M.3
Piacentini, M.4
-
14
-
-
66449083078
-
ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy
-
Ganley I.G., Lam H., Wang J., Ding X., Chen S., Jiang X. ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy. J.Biol. Chem. 2009, 284:12297-12305.
-
(2009)
J.Biol. Chem.
, vol.284
, pp. 12297-12305
-
-
Ganley, I.G.1
Lam, H.2
Wang, J.3
Ding, X.4
Chen, S.5
Jiang, X.6
-
15
-
-
81855181738
-
MTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR
-
Gao D., Inuzuka H., Tan M.K., Fukushima H., Locasale J.W., Liu P., Wan L., Zhai B., Chin Y.R., Shaik S., et al. mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol. Cell 2011, 44:290-303.
-
(2011)
Mol. Cell
, vol.44
, pp. 290-303
-
-
Gao, D.1
Inuzuka, H.2
Tan, M.K.3
Fukushima, H.4
Locasale, J.W.5
Liu, P.6
Wan, L.7
Zhai, B.8
Chin, Y.R.9
Shaik, S.10
-
16
-
-
84870680742
-
Understanding cullin-RING E3 biology through proteomics-based substrate identification
-
Harper J.W., Tan M.K. Understanding cullin-RING E3 biology through proteomics-based substrate identification. Mol. Cell. Proteomics 2012, 11:1541-1550.
-
(2012)
Mol. Cell. Proteomics
, vol.11
, pp. 1541-1550
-
-
Harper, J.W.1
Tan, M.K.2
-
18
-
-
33751112293
-
DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases
-
He Y.J., McCall C.M., Hu J., Zeng Y., Xiong Y. DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. Genes Dev. 2006, 20:2949-2954.
-
(2006)
Genes Dev.
, vol.20
, pp. 2949-2954
-
-
He, Y.J.1
McCall, C.M.2
Hu, J.3
Zeng, Y.4
Xiong, Y.5
-
19
-
-
84883464875
-
Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism
-
He C., Wei Y., Sun K., Li B., Dong X., Zou Z., Liu Y., Kinch L.N., Khan S., Sinha S., et al. Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism. Cell 2013, 154:1085-1099.
-
(2013)
Cell
, vol.154
, pp. 1085-1099
-
-
He, C.1
Wei, Y.2
Sun, K.3
Li, B.4
Dong, X.5
Zou, Z.6
Liu, Y.7
Kinch, L.N.8
Khan, S.9
Sinha, S.10
-
20
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
Hosokawa N., Hara T., Kaizuka T., Kishi C., Takamura A., Miura Y., Iemura S., Natsume T., Takehana K., Yamada N., et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol. Biol. Cell 2009, 20:1981-1991.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
Kishi, C.4
Takamura, A.5
Miura, Y.6
Iemura, S.7
Natsume, T.8
Takehana, K.9
Yamada, N.10
-
21
-
-
41649117158
-
WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase
-
Hu J., Zacharek S., He Y.J., Lee H., Shumway S., Duronio R.J., Xiong Y. WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase. Genes Dev. 2008, 22:866-871.
-
(2008)
Genes Dev.
, vol.22
, pp. 866-871
-
-
Hu, J.1
Zacharek, S.2
He, Y.J.3
Lee, H.4
Shumway, S.5
Duronio, R.J.6
Xiong, Y.7
-
22
-
-
77955884684
-
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
-
Itakura E., Mizushima N. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 2010, 6:764-776.
-
(2010)
Autophagy
, vol.6
, pp. 764-776
-
-
Itakura, E.1
Mizushima, N.2
-
23
-
-
33747873322
-
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1
-
Jin J., Arias E.E., Chen J., Harper J.W., Walter J.C. A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1. Mol. Cell 2006, 23:709-721.
-
(2006)
Mol. Cell
, vol.23
, pp. 709-721
-
-
Jin, J.1
Arias, E.E.2
Chen, J.3
Harper, J.W.4
Walter, J.C.5
-
24
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung C.H., Jun C.B., Ro S.H., Kim Y.M., Otto N.M., Cao J., Kundu M., Kim D.H. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol. Biol. Cell 2009, 20:1992-2003.
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
Kundu, M.7
Kim, D.H.8
-
25
-
-
10644276385
-
VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases
-
Kamura T., Maenaka K., Kotoshiba S., Matsumoto M., Kohda D., Conaway R.C., Conaway J.W., Nakayama K.I. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases. Genes Dev. 2004, 18:3055-3065.
-
(2004)
Genes Dev.
, vol.18
, pp. 3055-3065
-
-
Kamura, T.1
Maenaka, K.2
Kotoshiba, S.3
Matsumoto, M.4
Kohda, D.5
Conaway, R.C.6
Conaway, J.W.7
Nakayama, K.I.8
-
26
-
-
68249104457
-
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase
-
Katiyar S., Liu E., Knutzen C.A., Lang E.S., Lombardo C.R., Sankar S., Toth J.I., Petroski M.D., Ronai Z., Chiang G.G. REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase. EMBO Rep. 2009, 10:866-872.
-
(2009)
EMBO Rep.
, vol.10
, pp. 866-872
-
-
Katiyar, S.1
Liu, E.2
Knutzen, C.A.3
Lang, E.S.4
Lombardo, C.R.5
Sankar, S.6
Toth, J.I.7
Petroski, M.D.8
Ronai, Z.9
Chiang, G.G.10
-
27
-
-
79551598347
-
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
-
Kim J., Kundu M., Viollet B., Guan K.L. AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1. Nat. Cell Biol. 2011, 13:132-141.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 132-141
-
-
Kim, J.1
Kundu, M.2
Viollet, B.3
Guan, K.L.4
-
28
-
-
34548077575
-
Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3
-
Kimura S., Noda T., Yoshimori T. Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 2007, 3:452-460.
-
(2007)
Autophagy
, vol.3
, pp. 452-460
-
-
Kimura, S.1
Noda, T.2
Yoshimori, T.3
-
29
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky D.J., Abdalla F.C., Abeliovich H., Abraham R.T., Acevedo-Arozena A., Adeli K., Agholme L., Agnello M., Agostinis P., Aguirre-Ghiso J.A., et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 2012, 8:445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.J.1
Abdalla, F.C.2
Abeliovich, H.3
Abraham, R.T.4
Acevedo-Arozena, A.5
Adeli, K.6
Agholme, L.7
Agnello, M.8
Agostinis, P.9
Aguirre-Ghiso, J.A.10
-
30
-
-
79953316595
-
Lysosomal positioning coordinates cellular nutrient responses
-
Korolchuk V.I., Saiki S., Lichtenberg M., Siddiqi F.H., Roberts E.A., Imarisio S., Jahreiss L., Sarkar S., Futter M., Menzies F.M., et al. Lysosomal positioning coordinates cellular nutrient responses. Nat. Cell Biol. 2011, 13:453-460.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 453-460
-
-
Korolchuk, V.I.1
Saiki, S.2
Lichtenberg, M.3
Siddiqi, F.H.4
Roberts, E.A.5
Imarisio, S.6
Jahreiss, L.7
Sarkar, S.8
Futter, M.9
Menzies, F.M.10
-
31
-
-
84885662059
-
Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site
-
Koyama-Honda I., Itakura E., Fujiwara T.K., Mizushima N. Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site. Autophagy 2013, 9:1491-1499.
-
(2013)
Autophagy
, vol.9
, pp. 1491-1499
-
-
Koyama-Honda, I.1
Itakura, E.2
Fujiwara, T.K.3
Mizushima, N.4
-
32
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G., Mariño G., Levine B. Autophagy and the integrated stress response. Mol. Cell 2010, 40:280-293.
-
(2010)
Mol. Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Mariño, G.2
Levine, B.3
-
33
-
-
84864692282
-
DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity
-
Laplante M., Horvat S., Festuccia W.T., Birsoy K., Prevorsek Z., Efeyan A., Sabatini D.M. DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity. Cell Metab. 2012, 16:202-212.
-
(2012)
Cell Metab.
, vol.16
, pp. 202-212
-
-
Laplante, M.1
Horvat, S.2
Festuccia, W.T.3
Birsoy, K.4
Prevorsek, Z.5
Efeyan, A.6
Sabatini, D.M.7
-
34
-
-
84873559675
-
Pathogenic role of the CRL4 ubiquitin ligase in human disease
-
Lee J., Zhou P. Pathogenic role of the CRL4 ubiquitin ligase in human disease. Front. Oncol. 2012, 2:21.
-
(2012)
Front. Oncol.
, vol.2
, pp. 21
-
-
Lee, J.1
Zhou, P.2
-
35
-
-
84871975033
-
CRL ubiquitin ligases and DNA damage response
-
Li J.M., Jin J. CRL ubiquitin ligases and DNA damage response. Front. Oncol. 2012, 2:29.
-
(2012)
Front. Oncol.
, vol.2
, pp. 29
-
-
Li, J.M.1
Jin, J.2
-
36
-
-
84922541234
-
Autosis and autophagic cell death: the dark side of autophagy
-
Published online September 26, 2014
-
Liu Y., Levine B. Autosis and autophagic cell death: the dark side of autophagy. Cell Death Differ. 2014, Published online September 26, 2014. 10.1038/cdd.2014.143.
-
(2014)
Cell Death Differ.
-
-
Liu, Y.1
Levine, B.2
-
37
-
-
84863568271
-
The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth
-
Luo Z., Yu G., Lee H.W., Li L., Wang L., Yang D., Pan Y., Ding C., Qian J., Wu L., et al. The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. Cancer Res. 2012, 72:3360-3371.
-
(2012)
Cancer Res.
, vol.72
, pp. 3360-3371
-
-
Luo, Z.1
Yu, G.2
Lee, H.W.3
Li, L.4
Wang, L.5
Yang, D.6
Pan, Y.7
Ding, C.8
Qian, J.9
Wu, L.10
-
38
-
-
77951221542
-
The role of the Atg1/ULK1 complex in autophagy regulation
-
Mizushima N. The role of the Atg1/ULK1 complex in autophagy regulation. Curr. Opin. Cell Biol. 2010, 22:132-139.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 132-139
-
-
Mizushima, N.1
-
39
-
-
84866244791
-
Autophagy in protein and organelle turnover
-
Mizushima N. Autophagy in protein and organelle turnover. Cold Spring Harb. Symp. Quant. Biol. 2011, 76:397-402.
-
(2011)
Cold Spring Harb. Symp. Quant. Biol.
, vol.76
, pp. 397-402
-
-
Mizushima, N.1
-
41
-
-
84876488191
-
MTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
-
Nazio F., Strappazzon F., Antonioli M., Bielli P., Cianfanelli V., Bordi M., Gretzmeier C., Dengjel J., Piacentini M., Fimia G.M., Cecconi F. mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6. Nat. Cell Biol. 2013, 15:406-416.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 406-416
-
-
Nazio, F.1
Strappazzon, F.2
Antonioli, M.3
Bielli, P.4
Cianfanelli, V.5
Bordi, M.6
Gretzmeier, C.7
Dengjel, J.8
Piacentini, M.9
Fimia, G.M.10
Cecconi, F.11
-
42
-
-
79955580832
-
Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes
-
Nie L., Zhao Y., Wu W., Yang Y.Z., Wang H.C., Sun X.H. Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes. Cell Res. 2011, 21:754-769.
-
(2011)
Cell Res.
, vol.21
, pp. 754-769
-
-
Nie, L.1
Zhao, Y.2
Wu, W.3
Yang, Y.Z.4
Wang, H.C.5
Sun, X.H.6
-
43
-
-
84865174943
-
The Role of Elongin BC-Containing Ubiquitin Ligases
-
Okumura F., Matsuzaki M., Nakatsukasa K., Kamura T. The Role of Elongin BC-Containing Ubiquitin Ligases. Front. Oncol. 2012, 2:10.
-
(2012)
Front. Oncol.
, vol.2
, pp. 10
-
-
Okumura, F.1
Matsuzaki, M.2
Nakatsukasa, K.3
Kamura, T.4
-
44
-
-
84865155931
-
Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response
-
Pagliarini V., Wirawan E., Romagnoli A., Ciccosanti F., Lisi G., Lippens S., Cecconi F., Fimia G.M., Vandenabeele P., Corazzari M., Piacentini M. Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response. Cell Death Differ. 2012, 19:1495-1504.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1495-1504
-
-
Pagliarini, V.1
Wirawan, E.2
Romagnoli, A.3
Ciccosanti, F.4
Lisi, G.5
Lippens, S.6
Cecconi, F.7
Fimia, G.M.8
Vandenabeele, P.9
Corazzari, M.10
Piacentini, M.11
-
45
-
-
67349241955
-
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
-
Peterson T.R., Laplante M., Thoreen C.C., Sancak Y., Kang S.A., Kuehl W.M., Gray N.S., Sabatini D.M. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell 2009, 137:873-886.
-
(2009)
Cell
, vol.137
, pp. 873-886
-
-
Peterson, T.R.1
Laplante, M.2
Thoreen, C.C.3
Sancak, Y.4
Kang, S.A.5
Kuehl, W.M.6
Gray, N.S.7
Sabatini, D.M.8
-
46
-
-
11244351579
-
Function and regulation of cullin-RING ubiquitin ligases
-
Petroski M.D., Deshaies R.J. Function and regulation of cullin-RING ubiquitin ligases. Nat. Rev. Mol. Cell Biol. 2005, 6:9-20.
-
(2005)
Nat. Rev. Mol. Cell Biol.
, vol.6
, pp. 9-20
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
47
-
-
77951768486
-
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
-
Sancak Y., Bar-Peled L., Zoncu R., Markhard A.L., Nada S., Sabatini D.M. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 2010, 141:290-303.
-
(2010)
Cell
, vol.141
, pp. 290-303
-
-
Sancak, Y.1
Bar-Peled, L.2
Zoncu, R.3
Markhard, A.L.4
Nada, S.5
Sabatini, D.M.6
-
49
-
-
80955177196
-
TFEB links autophagy to lysosomal biogenesis
-
Settembre C., Di Malta C., Polito V.A., Garcia Arencibia M., Vetrini F., Erdin S., Erdin S.U., Huynh T., Medina D., Colella P., et al. TFEB links autophagy to lysosomal biogenesis. Science 2011, 332:1429-1433.
-
(2011)
Science
, vol.332
, pp. 1429-1433
-
-
Settembre, C.1
Di Malta, C.2
Polito, V.A.3
Garcia Arencibia, M.4
Vetrini, F.5
Erdin, S.6
Erdin, S.U.7
Huynh, T.8
Medina, D.9
Colella, P.10
-
50
-
-
84856421054
-
Beclin1: a role in membrane dynamics and beyond
-
Wirawan E., Lippens S., Vanden Berghe T., Romagnoli A., Fimia G.M., Piacentini M., Vandenabeele P. Beclin1: a role in membrane dynamics and beyond. Autophagy 2012, 8:6-17.
-
(2012)
Autophagy
, vol.8
, pp. 6-17
-
-
Wirawan, E.1
Lippens, S.2
Vanden Berghe, T.3
Romagnoli, A.4
Fimia, G.M.5
Piacentini, M.6
Vandenabeele, P.7
-
51
-
-
84873675067
-
The ULK1 complex: sensing nutrient signals for autophagy activation
-
Wong P.M., Puente C., Ganley I.G., Jiang X. The ULK1 complex: sensing nutrient signals for autophagy activation. Autophagy 2013, 9:124-137.
-
(2013)
Autophagy
, vol.9
, pp. 124-137
-
-
Wong, P.M.1
Puente, C.2
Ganley, I.G.3
Jiang, X.4
-
52
-
-
84885869476
-
WASH inhibits autophagy through suppression of Beclin 1 ubiquitination
-
Xia P., Wang S., Du Y., Zhao Z., Shi L., Sun L., Huang G., Ye B., Li C., Dai Z., et al. WASH inhibits autophagy through suppression of Beclin 1 ubiquitination. EMBO J. 2013, 32:2685-2696.
-
(2013)
EMBO J.
, vol.32
, pp. 2685-2696
-
-
Xia, P.1
Wang, S.2
Du, Y.3
Zhao, Z.4
Shi, L.5
Sun, L.6
Huang, G.7
Ye, B.8
Li, C.9
Dai, Z.10
-
53
-
-
84905582805
-
RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy
-
Xia P., Wang S., Huang G., Du Y., Zhu P., Li M., Fan Z. RNF2 is recruited by WASH to ubiquitinate AMBRA1 leading to downregulation of autophagy. Cell Res. 2014, 24:943-958.
-
(2014)
Cell Res.
, vol.24
, pp. 943-958
-
-
Xia, P.1
Wang, S.2
Huang, G.3
Du, Y.4
Zhu, P.5
Li, M.6
Fan, Z.7
-
54
-
-
43449092174
-
The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation
-
Xu X., Sarikas A., Dias-Santagata D.C., Dolios G., Lafontant P.J., Tsai S.C., Zhu W., Nakajima H., Nakajima H.O., Field L.J., et al. The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation. Mol. Cell 2008, 30:403-414.
-
(2008)
Mol. Cell
, vol.30
, pp. 403-414
-
-
Xu, X.1
Sarikas, A.2
Dias-Santagata, D.C.3
Dolios, G.4
Lafontant, P.J.5
Tsai, S.C.6
Zhu, W.7
Nakajima, H.8
Nakajima, H.O.9
Field, L.J.10
-
55
-
-
84872320049
-
Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells
-
Yang D., Li L., Liu H., Wu L., Luo Z., Li H., Zheng S., Gao H., Chu Y., Sun Y., et al. Induction of autophagy and senescence by knockdown of ROC1 E3 ubiquitin ligase to suppress the growth of liver cancer cells. Cell Death Differ. 2013, 20:235-247.
-
(2013)
Cell Death Differ.
, vol.20
, pp. 235-247
-
-
Yang, D.1
Li, L.2
Liu, H.3
Wu, L.4
Luo, Z.5
Li, H.6
Zheng, S.7
Gao, H.8
Chu, Y.9
Sun, Y.10
-
56
-
-
77953699711
-
Termination of autophagy and reformation of lysosomes regulated by mTOR
-
Yu L., McPhee C.K., Zheng L., Mardones G.A., Rong Y., Peng J., Mi N., Zhao Y., Liu Z., Wan F., et al. Termination of autophagy and reformation of lysosomes regulated by mTOR. Nature 2010, 465:942-946.
-
(2010)
Nature
, vol.465
, pp. 942-946
-
-
Yu, L.1
McPhee, C.K.2
Zheng, L.3
Mardones, G.A.4
Rong, Y.5
Peng, J.6
Mi, N.7
Zhao, Y.8
Liu, Z.9
Wan, F.10
-
57
-
-
81855167585
-
DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy
-
Zhao Y., Xiong X., Sun Y. DEPTOR, an mTOR inhibitor, is a physiological substrate of SCF(βTrCP) E3 ubiquitin ligase and regulates survival and autophagy. Mol. Cell 2011, 44:304-316.
-
(2011)
Mol. Cell
, vol.44
, pp. 304-316
-
-
Zhao, Y.1
Xiong, X.2
Sun, Y.3
-
58
-
-
84867204635
-
Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis
-
Zhao Y., Xiong X., Jia L., Sun Y. Targeting Cullin-RING ligases by MLN4924 induces autophagy via modulating the HIF1-REDD1-TSC1-mTORC1-DEPTOR axis. Cell Death Dis. 2012, 3:e386.
-
(2012)
Cell Death Dis.
, vol.3
, pp. e386
-
-
Zhao, Y.1
Xiong, X.2
Jia, L.3
Sun, Y.4
-
59
-
-
80555143078
-
MTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
-
Zoncu R., Bar-Peled L., Efeyan A., Wang S., Sancak Y., Sabatini D.M. mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase. Science 2011, 334:678-683.
-
(2011)
Science
, vol.334
, pp. 678-683
-
-
Zoncu, R.1
Bar-Peled, L.2
Efeyan, A.3
Wang, S.4
Sancak, Y.5
Sabatini, D.M.6
|