Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 21, 2015, Pages 6637-6642

  Ordureau, Alban ^a   Heo, Jin Mi ^a   Duda, David M ^b   Paulo, Joao A ^a   Olszewski, Jennifer L ^b   Yanishevski, David ^b   Rinehart, Jesse ^c   Schulman, Brenda A ^b   Harper, J Wade ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Mitochondria; PARKIN; Phosphorylation; PINK1; Ubiquitin

Indexed keywords

PARKIN; PROTEIN KINASE; PTEN INDUCED PUTATIVE KINASE PROTEIN 1; UBIQUITIN; UNCLASSIFIED DRUG; MITOCHONDRIAL PROTEIN; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

ARTICLE; CELL MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MITOPHAGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; UBIQUITINATION; BIOLOGICAL MODEL; CELL LINE; CHEMISTRY; HELA CELL LINE; HUMAN; METABOLISM; MITOCHONDRION; PHOSPHORYLATION;

CELL LINE; HELA CELLS; HUMANS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN KINASES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84929691103     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1506593112     Document Type: Article

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