The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response

Nature

Volumn 483, Issue 7391, 2012, Pages 623-626

  Sanada, Takahito ^a   Kim, Minsoo ^a   Mimuro, Hitomi ^a   Suzuki, Masato ^a   Ogawa, Michinaga ^a   Oyama, Akiho ^a   Ashida, Hiroshi ^a   Kobayashi, Taira ^a   Koyama, Tomohiro ^b   Nagai, Shinya ^b   Shibata, Yuri ^a   Gohda, Jin ^a   Inoue, Jun Ichiro ^a   Mizushima, Tsunehiro ^c   Sasakawa, Chihiro ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b NIPPON INSTITUTE FOR BIOLOGICAL SCIENCE   (Japan)

^c UNIVERSITY OF HYOGO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; GLUTAMIC ACID; GLUTAMINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSPI PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UBIQUITIN CONJUGATING ENZYME 13; UBIQUITIN CONJUGATING ENZYME E2; UNCLASSIFIED DRUG;

BACTERIUM; CRYSTAL STRUCTURE; CYTOLOGY; IMMUNE SYSTEM; MOLECULAR ANALYSIS; MUTATION; PATHOGEN; PLASMID; SECRETION; SURVIVAL; TUMOR;

ARTICLE; CRYSTAL STRUCTURE; INFLAMMATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMIDOHYDROLASES; AMINO ACID SEQUENCE; ANIMALS; ASPARTIC ACID; BIOCATALYSIS; CASPASES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DIGLYCERIDES; DNA MUTATIONAL ANALYSIS; DYSENTERY, BACILLARY; GLUTAMIC ACID; GLUTAMINE; HEK293 CELLS; HELA CELLS; HISTIDINE; HUMANS; IMMUNITY, INNATE; INFLAMMATION; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; NF-KAPPA B; SHIGELLA FLEXNERI; TNF RECEPTOR-ASSOCIATED FACTOR 6; UBIQUITIN-CONJUGATING ENZYMES; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); SHIGELLA FLEXNERI;

EID: 84862818454     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10894     Document Type: Article

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