The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

Nature

Volumn 524, Issue 7565, 2015, Pages 309-314

  Lazarou, Michael ^a,b   Sliter, Danielle A ^a   Kane, Lesley A ^a   Sarraf, Shireen A ^a   Wang, Chunxin ^a   Burman, Jonathon L ^a   Sideris, Dionisia P ^a   Fogel, Adam I ^a   Youle, Richard J ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

OPTINEURIN; OUTER MEMBRANE PROTEIN; PARKIN; PHOSPHOTRANSFERASE; PINK1 PROTEIN; PROTEIN P62; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CARRIER PROTEIN; MAP1LC3B PROTEIN, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; MITOCHONDRIAL PROTEIN; NUCLEAR DOT PROTEIN 52, HUMAN; NUCLEAR PROTEIN; OPTN PROTEIN, HUMAN; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; PTEN-INDUCED PUTATIVE KINASE; SIGNAL PEPTIDE; TBK1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR IIIA; UBIQUITIN; ULK1 PROTEIN, HUMAN; WIPI-1 PROTEIN, HUMAN; ZFYVE1 PROTEIN, HUMAN;

CELLS AND CELL COMPONENTS; ENZYME ACTIVITY; MITOCHONDRION; PROTEIN;

ARTICLE; AUTOPHAGY; AUTOPHOSPHORYLATION; CYTOSOL; FEMALE; GENOME; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOPHAGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; XENOPHAGY; BIOLOGICAL MODEL; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; PHYSIOLOGY;

AUTOPHAGY; CARRIER PROTEINS; HELA CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR TFIIIA; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84939804206     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14893     Document Type: Article

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