Role of histone H3 lysine 27 methylation in polycomb-group silencing

Science

Volumn 298, Issue 5595, 2002, Pages 1039-1043

  Cao, Ru ^a   Wang, Liangjun ^a   Wang, Hengbin ^a   Xia, Li ^a   Erdjument Bromage, Hediye ^a   Tempst, Paul ^a   Jones, Richard S ^a   Zhang, Yi ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; ASSAYS; GENES;

IMMUNOPRECIPITATION;

PROTEINS;

HISTONE H3; HISTONE METHYLTRANSFERASE; LYSINE; METHYLTRANSFERASE; UNCLASSIFIED DRUG;

GENETICS; PROTEIN;

ARTICLE; CHROMATIN; COMPLEX FORMATION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; ENZYME SPECIFICITY; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN METHYLATION;

ANIMALS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CHROMATIN; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE SILENCING; GENES, HOMEOBOX; HELA CELLS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; LYSINE; METHYLATION; METHYLTRANSFERASES; NUCLEAR PROTEINS; NUCLEOSOMES; PEPTIDE MAPPING; PRECIPITIN TESTS; PROTEINS; REPRESSOR PROTEINS; RESPONSE ELEMENTS; RNA INTERFERENCE; TEMPERATURE; TRANSCRIPTION FACTORS;

EID: 0036830642     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1076997     Document Type: Article

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35. We thank T. Nagases, T. Magnuson, A. Verreault, H. Chen, A. Otte, A. Ullrich, K. Bomsztyk, and K. Luger for plasmids; H.-H. Ng for yeast histones; T. Jenuwein and P. O'Farrell for antibodies; and E. Henry for critical reading of the manuscript. Y.Z. is a Kimmel Scholar and is supported by grants from the NIH and American Cancer Society. This work was also supported by an NIH grant (to R.S.J.) and a National Cancer Institute grant (to P.T.).