Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis

Molecular Cell

Volumn 56, Issue 3, 2014, Pages 360-375

  Ordureau, Alban ^a   Sarraf, Shireen A ^a   Duda, David M ^b   Heo, Jin Mi ^a   Jedrychowski, Mark P ^a   Sviderskiy, Vladislav O ^b   Olszewski, Jennifer L ^b   Koerber, James T ^c   Xie, Tiao ^a   Beausoleil, Sean A ^d   Wells, James A ^c   Gygi, Steven P ^a   Schulman, Brenda A ^b   Harper, J Wade ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Cell Signaling Technologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMYCIN A1; MITOCHONDRIAL PROTEIN; OLIGOMYCIN; PARKIN; PINK1 KINASE; PROTEIN KINASE; UBIQUITIN; UNCLASSIFIED DRUG; POLYUBIQUITIN; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE; CYSTEINE;

ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; DEPOLARIZATION; FIBROBLAST; GEL PERMEATION CHROMATOGRAPHY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIGHT SCATTERING; LINKAGE ANALYSIS; LIQUID CHROMATOGRAPHY; MITOCHONDRION; MOUSE; MULTIANGLE LIGHT SCATTERING; NONHUMAN; PARKINSON DISEASE; PHENOTYPE; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEOMICS; QUANTITATIVE ANALYSIS; STOICHIOMETRY; TANDEM MASS SPECTROMETRY; UBIQUITINATION; WESTERN BLOTTING; BIOSYNTHESIS; ENZYMOLOGY; FEEDBACK SYSTEM; GENETICS; HELA CELL LINE; METABOLISM; MISSENSE MUTATION; MITOCHONDRIAL MEMBRANE POTENTIAL; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; CATALYSIS; CELL DAMAGE; ERRATUM; FEMALE; IN VITRO STUDY; PROTEIN FUNCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

FEEDBACK, PHYSIOLOGICAL; HELA CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MUTATION, MISSENSE; PARKINSON DISEASE; PHOSPHORYLATION; POLYUBIQUITIN; PROTEIN KINASES; PROTEIN MULTIMERIZATION; PROTEIN TRANSPORT; PROTEOMICS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84922434418     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.09.007     Document Type: Article

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