The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins

Molecular Cell

Volumn 59, Issue 1, 2015, Pages 35-49

  Higgins, Reneé ^a   Gendron, Joshua M ^a,d   Rising, Lisa ^a   Mak, Raymond ^a   Webb, Kristofor ^a,e   Kaiser, Stephen E ^b   Zuzow, Nathan ^a   Riviere, Paul ^a   Yang, Bing ^a   Fenech, Emma ^c   Tang, Xin ^a   Lindsay, Scott A ^a   Christianson, John C ^c   Hampton, Randolph Y ^a   Wasserman, Steven A ^a   Bennett, Eric J ^a  

^a SECTION OF CELL AND DEVELOPMENTAL BIOLOGY   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d YALE UNIVERSITY   (United States)

^e Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; AMINO ACID TRANSPORTER; EPOXOMICIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; LYSINE; PROTEASOME; PROTEIN; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE; PROTEOME; RIBOSOME PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; EIF2AK3 PROTEIN, HUMAN; INITIATION FACTOR 2; PROTEIN KINASE R;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL DEATH; CELL FRACTIONATION; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENSITY GRADIENT; DOWN REGULATION; DROSOPHILA; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; HCT116 CELL LINE; HEAT SHOCK; HISTONE UBIQUITINATION; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEOMICS; RIBOSOME; RIBOSOME SUBUNIT; RNA TRANSLATION; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSLATION INITIATION; UBIQUITINATION; UNFOLDED PROTEIN RESPONSE; YEAST CELL; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; PHYSIOLOGY; SMALL RIBOSOMAL SUBUNIT;

EUKARYOTA;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL SURVIVAL; DROSOPHILA; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; GENE EXPRESSION REGULATION; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RIBOSOME SUBUNITS, SMALL, EUKARYOTIC; SACCHAROMYCES CEREVISIAE; UBIQUITINATION; UNFOLDED PROTEIN RESPONSE;

EID: 84934448890     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.04.026     Document Type: Article

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