USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A

Nature Communications

Volumn 9, Issue 1, 2018, Pages

  Uckelmann, Michael ^a   Densham, Ruth M ^b   Baas, Roy ^a   Winterwerp, Herrie H K ^a   Fish, Alexander ^a   Sixma, Titia K ^a   Morris, Joanna R ^b  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA1 PROTEIN; CAMPTOTHECIN; DEUBIQUITINASE; HISTONE H2A; TUMOR SUPPRESSOR P53 BINDING PROTEIN 1; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN SPECIFIC PROTEASE 48; UNCLASSIFIED DRUG; BRCA1 PROTEIN, HUMAN; HISTONE; TP53BP1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE; USP48 PROTEIN, HUMAN;

CELL; DNA; DRUG; ENZYME; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENOME; PROTEIN; RECOMBINATION;

ARTICLE; BIOCHEMICAL ANALYSIS; CARBOXY TERMINAL SEQUENCE; CELL LOSS; CELL SURVIVAL; CHROMATIN; CONTROLLED STUDY; DNA DAMAGE RESPONSE; GENE CONVERSION; GENOMIC INSTABILITY; HELA CELL LINE; HISTONE UBIQUITINATION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; MUTAGENESIS; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; ANIMAL; CELL CULTURE; DNA REPAIR; GENETICS; KINETICS; KNOCKOUT MOUSE; METABOLISM; NUCLEOTIDE SEQUENCE; RNA INTERFERENCE; TUMOR CELL LINE; UBIQUITINATION;

ANIMALS; BASE SEQUENCE; BRCA1 PROTEIN; CELL LINE, TUMOR; CELLS, CULTURED; DNA REPAIR; HELA CELLS; HISTONES; HUMANS; KINETICS; MICE, KNOCKOUT; RNA INTERFERENCE; TUMOR SUPPRESSOR P53-BINDING PROTEIN 1; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITIN-SPECIFIC PROTEASES; UBIQUITINATION;

EID: 85040792488     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-02653-3     Document Type: Article

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