Mechanism of phospho-ubiquitin-induced PARKIN activation

Nature

Volumn 524, Issue 7565, 2015, Pages 370-374

  Wauer, Tobias ^a   Simicek, Michal ^a   Schubert, Alexander ^a   Komander, David ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PARKIN; UBIQUITIN; PHOSPHATE; PHOSPHOPROTEIN; PROTEIN BINDING; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

CRYSTAL STRUCTURE; ENZYME ACTIVITY; JUVENILE; LOUSE; MITOCHONDRION; MUTATION; NERVOUS SYSTEM DISORDER; POLARIZATION;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HELA CELL LINE; HUMAN; HUMAN CELL; NONHUMAN; PEDICULUS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVATION; GENETICS; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PARKINSONISM; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

PEDICULUS HUMANUS;

ANIMALS; BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; MUTATION; PARKINSONIAN DISORDERS; PEDICULUS; PHOSPHATES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 84939795423     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14879     Document Type: Article

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