Mechanisms of deubiquitinase specificity and regulation

Annual Review of Biochemistry

Volumn 86, Issue , 2017, Pages 159-192

  Mevissen, Tycho E T ^a   Komander, David ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

Allosteric regulation; Deubiquitinase; Linkage specificity; Posttranslational modification; Substrate assisted catalysis; Ubiquitin code

Indexed keywords

AMSH LIKE PROTEIN; CEZANNE ENZYME; COP9 SIGNALOSOME; CYLD ENZYME; DEUBIQUITINASE; ENZYME; METALLOPROTEINASE; METALLOPROTEINASE AMSH; OTULIN ENZYME; PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; NEDD8 PROTEIN, HUMAN; PROTEIN BINDING; UBIQUITIN PROTEIN LIGASE;

ALLOSTERISM; BINDING SITE; CELL STRUCTURE; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; HUMAN; MACROMOLECULE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SACCHAROMYCES CEREVISIAE; SUMOYLATION; UBIQUITINATION; ACETYLATION; CHEMISTRY; EUKARYOTIC CELL; GENETICS; METABOLISM; MOLECULAR MODEL; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION;

ACETYLATION; ALLOSTERIC REGULATION; DEUBIQUITINATING ENZYMES; EUKARYOTIC CELLS; HUMANS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOLYSIS; SUBSTRATE SPECIFICITY; SUMOYLATION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; UBIQUITINS;

EID: 85021674924     PISSN: 00664154     EISSN: 15454509     Source Type: Book Series    
DOI: 10.1146/annurev-biochem-061516-044916     Document Type: Review

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