Marked for death: Targeting epigenetic changes in cancer

Nature Reviews Drug Discovery

Volumn 16, Issue 4, 2017, Pages 241-263

  Pfister, Sophia Xiao ^a   Ashworth, Alan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HISTONE H3; HISTONE H3 LYSINE 36; HYBRID PROTEIN; UNCLASSIFIED DRUG; ENZYME INHIBITOR;

BET GENE; CANCER GENETICS; CANCER IMMUNOLOGY; CANCER IMMUNOTHERAPY; CANCER RESEARCH; CBP GENE; CHROMATIN ASSEMBLY AND DISASSEMBLY; DNA METHYLATION; DNMT GENE; DRUG DEVELOPMENT; DRUG RESEARCH; DRUG RESISTANCE; DRUG SCREENING; EPIGENETICS; EZH2 GENE; FUNCTIONAL GENOMICS; GAIN OF FUNCTION MUTATION; GENE; GENE LOSS; GENE TARGETING; GENE THERAPY; HDAC GENE; HDM GENE; HISTONE ACETYLATION; HISTONE DEMETHYLATION; HISTONE METHYLATION; HMT GENE; HUMAN; IDH GENE; LOSS OF FUNCTION MUTATION; NONHUMAN; P300 GENE; PRMT5 GENE; REVIEW; STRUCTURE ACTIVITY RELATION; SWI SNF COMPLEX GENE; BIOLOGICAL MODEL; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; MOLECULARLY TARGETED THERAPY; MUTATION; NEOPLASMS; PROCEDURES; TRENDS;

DRUG DISCOVERY; ENZYME INHIBITORS; EPIGENESIS, GENETIC; HUMANS; MODELS, GENETIC; MOLECULAR TARGETED THERAPY; MUTATION; NEOPLASMS;

EID: 85014690636     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd.2016.256     Document Type: Review

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