Inhibitors of histone deacetylase 1 reverse the immune evasion phenotype to enhance T-cell mediated lysis of prostate and breast carcinoma cells

Oncotarget

Volumn 7, Issue 7, 2016, Pages 7390-7402

  Gameiro, Sofia R ^a   Malamas, Anthony S ^a   Tsang, Kwong Y ^a   Ferrone, Soldano ^b   Hodge, James W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Antigen processing machinery; Entinostat; Histone deacetylases; Immunogenic modulation; Vorinostat

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; ENTINOSTAT; HISTONE DEACETYLASE 1; MUCIN 1; PROSTATE SPECIFIC ANTIGEN; VORINOSTAT; BENZAMIDE DERIVATIVE; HDAC1 PROTEIN, HUMAN; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; PYRIDINE DERIVATIVE;

ANTIGEN RECOGNITION; ARTICLE; BREAST CARCINOMA; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CARCINOMA CELL LINE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EPIGENETICS; HUMAN; HUMAN CELL; IMMUNE EVASION; IMMUNOMODULATION; IN VITRO STUDY; MALE; PHENOTYPE; PROSTATE CARCINOMA; PROTEIN EXPRESSION; TUMOR CELL DESTRUCTION; UNFOLDED PROTEIN RESPONSE; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BREAST NEOPLASMS; CELL PROLIFERATION; DRUG EFFECTS; ENZYME IMMUNOASSAY; FEMALE; FLOW CYTOMETRY; IMMUNOLOGY; PATHOLOGY; PROSTATIC NEOPLASMS; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; TUMOR CELL CULTURE; WESTERN BLOTTING;

APOPTOSIS; BENZAMIDES; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; IMMUNE EVASION; IMMUNOENZYME TECHNIQUES; MALE; PROSTATIC NEOPLASMS; PYRIDINES; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; TUMOR CELLS, CULTURED;

EID: 84958818416     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.7180     Document Type: Article

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