-
1
-
-
0035839952
-
Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins
-
P.M. Ayton, and M.L. Cleary Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins Oncogene 20 2001 5695 5707
-
(2001)
Oncogene
, vol.20
, pp. 5695-5707
-
-
Ayton, P.M.1
Cleary, M.L.2
-
2
-
-
0041370095
-
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
-
P.M. Ayton, and M.L. Cleary Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9 Genes Dev. 17 2003 2298 2307
-
(2003)
Genes Dev.
, vol.17
, pp. 2298-2307
-
-
Ayton, P.M.1
Cleary, M.L.2
-
3
-
-
0142105414
-
EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
-
A.P. Bracken, D. Pasini, M. Capra, E. Prosperini, E. Colli, and K. Helin EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer EMBO J. 22 2003 5323 5335
-
(2003)
EMBO J.
, vol.22
, pp. 5323-5335
-
-
Bracken, A.P.1
Pasini, D.2
Capra, M.3
Prosperini, E.4
Colli, E.5
Helin, K.6
-
4
-
-
0034203281
-
Homeobox genes in leukemogenesis
-
C. Buske, and R.K. Humphries Homeobox genes in leukemogenesis Int. J. Hematol. 71 2000 301 308
-
(2000)
Int. J. Hematol.
, vol.71
, pp. 301-308
-
-
Buske, C.1
Humphries, R.K.2
-
5
-
-
0033768080
-
The amino terminus targets the mixed lineage leukemia (MLL) protein to the nucleolus, nuclear matrix and mitotic chromosomal scaffolds
-
C. Caslini, A.S. Alarcon, J.L. Hess, R. Tanaka, K.G. Murti, and A. Biondi The amino terminus targets the mixed lineage leukemia (MLL) protein to the nucleolus, nuclear matrix and mitotic chromosomal scaffolds Leukemia 14 2000 1898 1908
-
(2000)
Leukemia
, vol.14
, pp. 1898-1908
-
-
Caslini, C.1
Alarcon, A.S.2
Hess, J.L.3
Tanaka, R.4
Murti, K.G.5
Biondi, A.6
-
6
-
-
0029130257
-
The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene
-
T. Chaplin, O. Bernard, H.B. Beverloo, V. Saha, A. Hagemeijer, R. Berger, and B.D. Young The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene Blood 86 1995 2073 2076
-
(1995)
Blood
, vol.86
, pp. 2073-2076
-
-
Chaplin, T.1
Bernard, O.2
Beverloo, H.B.3
Saha, V.4
Hagemeijer, A.5
Berger, R.6
Young, B.D.7
-
7
-
-
0242290924
-
A genetic approach to inactivating chemokine receptors using a modified viral protein
-
V.M. Coffield, Q. Jiang, and L. Su A genetic approach to inactivating chemokine receptors using a modified viral protein Nat. Biotechnol. 21 2003 1321 1327
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1321-1327
-
-
Coffield, V.M.1
Jiang, Q.2
Su, L.3
-
8
-
-
2442591839
-
Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis
-
A. Daser, and T.H. Rabbitts Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis Genes Dev. 18 2004 965 974
-
(2004)
Genes Dev.
, vol.18
, pp. 965-974
-
-
Daser, A.1
Rabbitts, T.H.2
-
9
-
-
0032831130
-
Mll rearrangements in haematological malignancies: Lessons from clinical and biological studies
-
J.F. Dimartino, and M.L. Cleary Mll rearrangements in haematological malignancies: lessons from clinical and biological studies Br. J. Haematol. 106 1999 614 626
-
(1999)
Br. J. Haematol.
, vol.106
, pp. 614-626
-
-
Dimartino, J.F.1
Cleary, M.L.2
-
10
-
-
0037093081
-
The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10
-
J.F. DiMartino, P.M. Ayton, E.H. Chen, C.C. Naftzger, B.D. Young, and M.L. Cleary The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10 Blood 99 2002 3780 3785
-
(2002)
Blood
, vol.99
, pp. 3780-3785
-
-
Dimartino, J.F.1
Ayton, P.M.2
Chen, E.H.3
Naftzger, C.C.4
Young, B.D.5
Cleary, M.L.6
-
11
-
-
0029953937
-
The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family
-
M.H. Dreyling, J.A. Martinez-Climent, M. Zheng, J. Mao, J.D. Rowley, and S.K. Bohlander The t(10;11)(p13;q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family Proc. Natl. Acad. Sci. USA 93 1996 4804 4809
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4804-4809
-
-
Dreyling, M.H.1
Martinez-Climent, J.A.2
Zheng, M.3
Mao, J.4
Rowley, J.D.5
Bohlander, S.K.6
-
12
-
-
0037172665
-
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain
-
Q. Feng, H. Wang, H.H. Ng, H. Erdjument-Bromage, P. Tempst, K. Struhl, and Y. Zhang Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain Curr. Biol. 12 2002 1052 1058
-
(2002)
Curr. Biol.
, vol.12
, pp. 1052-1058
-
-
Feng, Q.1
Wang, H.2
Ng, H.H.3
Erdjument-Bromage, H.4
Tempst, P.5
Struhl, K.6
Zhang, Y.7
-
13
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
T.R. Golub, D.K. Slonim, P. Tamayo, C. Huard, M. Gaasenbeek, J.P. Mesirov, H. Coller, M.L. Loh, J.R. Downing, and M.A. Caligiuri Molecular classification of cancer: class discovery and class prediction by gene expression monitoring Science 286 1999 531 537
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
Huard, C.4
Gaasenbeek, M.5
Mesirov, J.P.6
Coller, H.7
Loh, M.L.8
Downing, J.R.9
Caligiuri, M.A.10
-
14
-
-
0345276803
-
Taspase1: A threonine aspartase required for cleavage of MLL and proper HOX gene expression
-
J.J. Hsieh, E.H. Cheng, and S.J. Korsmeyer Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression Cell 115 2003 293 303
-
(2003)
Cell
, vol.115
, pp. 293-303
-
-
Hsieh, J.J.1
Cheng, E.H.2
Korsmeyer, S.J.3
-
15
-
-
10744224167
-
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus
-
C.M. Hughes, O. Rozenblatt-Rosen, T.A. Milne, T.D. Copeland, S.S. Levine, J.C. Lee, D.N. Hayes, K.S. Shanmugam, A. Bhattacharjee, and C.A. Biondi Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus Mol. Cell 13 2004 587 597
-
(2004)
Mol. Cell
, vol.13
, pp. 587-597
-
-
Hughes, C.M.1
Rozenblatt-Rosen, O.2
Milne, T.A.3
Copeland, T.D.4
Levine, S.S.5
Lee, J.C.6
Hayes, D.N.7
Shanmugam, K.S.8
Bhattacharjee, A.9
Biondi, C.A.10
-
16
-
-
0141816752
-
EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
-
C.G. Kleer, Q. Cao, S. Varambally, R. Shen, I. Ota, S.A. Tomlins, D. Ghosh, R.G. Sewalt, A.P. Otte, and D.F. Hayes EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells Proc. Natl. Acad. Sci. USA 100 2003 11606 11611
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11606-11611
-
-
Kleer, C.G.1
Cao, Q.2
Varambally, S.3
Shen, R.4
Ota, I.5
Tomlins, S.A.6
Ghosh, D.7
Sewalt, R.G.8
Otte, A.P.9
Hayes, D.F.10
-
17
-
-
0032126633
-
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
-
E. Kroon, J. Krosl, U. Thorsteinsdottir, S. Baban, A.M. Buchberg, and G. Sauvageau Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b EMBO J. 17 1998 3714 3725
-
(1998)
EMBO J.
, vol.17
, pp. 3714-3725
-
-
Kroon, E.1
Krosl, J.2
Thorsteinsdottir, U.3
Baban, S.4
Buchberg, A.M.5
Sauvageau, G.6
-
18
-
-
0037672689
-
An epigenetic road map for histone lysine methylation
-
M. Lachner, R.J. O'Sullivan, and T. Jenuwein An epigenetic road map for histone lysine methylation J. Cell Sci. 116 2003 2117 2124
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2117-2124
-
-
Lachner, M.1
O'Sullivan, R.J.2
Jenuwein, T.3
-
19
-
-
18744373853
-
MLL targets SET domain methyltransferase activity to Hox gene promoters
-
T.A. Milne, S.D. Briggs, H.W. Brock, M.E. Martin, D. Gibbs, C.D. Allis, and J.L. Hess MLL targets SET domain methyltransferase activity to Hox gene promoters Mol. Cell 10 2002 1107 1117
-
(2002)
Mol. Cell
, vol.10
, pp. 1107-1117
-
-
Milne, T.A.1
Briggs, S.D.2
Brock, H.W.3
Martin, M.E.4
Gibbs, D.5
Allis, C.D.6
Hess, J.L.7
-
20
-
-
0344837759
-
Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
-
J. Min, Q. Feng, Z. Li, Y. Zhang, and R.M. Xu Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase Cell 112 2003 711 723
-
(2003)
Cell
, vol.112
, pp. 711-723
-
-
Min, J.1
Feng, Q.2
Li, Z.3
Zhang, Y.4
Xu, R.M.5
-
21
-
-
0041624288
-
Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
-
J. Min, Y. Zhang, and R.M. Xu Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27 Genes Dev. 17 2003 1823 1828
-
(2003)
Genes Dev.
, vol.17
, pp. 1823-1828
-
-
Min, J.1
Zhang, Y.2
Xu, R.M.3
-
22
-
-
0029819070
-
Identification of a new family of Pbx-related homeobox genes
-
T. Nakamura, N.A. Jenkins, and N.G. Copeland Identification of a new family of Pbx-related homeobox genes Oncogene 13 1996 2235 2242
-
(1996)
Oncogene
, vol.13
, pp. 2235-2242
-
-
Nakamura, T.1
Jenkins, N.A.2
Copeland, N.G.3
-
23
-
-
18744410349
-
ALL-1 Is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation
-
T. Nakamura, T. Mori, S. Tada, W. Krajewski, T. Rozovskaia, R. Wassell, G. Dubois, A. Mazo, C.M. Croce, and E. Canaani ALL-1 Is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation Mol. Cell 10 2002 1119 1128
-
(2002)
Mol. Cell
, vol.10
, pp. 1119-1128
-
-
Nakamura, T.1
Mori, T.2
Tada, S.3
Krajewski, W.4
Rozovskaia, T.5
Wassell, R.6
Dubois, G.7
Mazo, A.8
Croce, C.M.9
Canaani, E.10
-
24
-
-
0037098044
-
Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association
-
H.H. Ng, Q. Feng, H. Wang, H. Erdjument-Bromage, P. Tempst, Y. Zhang, and K. Struhl Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association Genes Dev. 16 2002 1518 1527
-
(2002)
Genes Dev.
, vol.16
, pp. 1518-1527
-
-
Ng, H.H.1
Feng, Q.2
Wang, H.3
Erdjument-Bromage, H.4
Tempst, P.5
Zhang, Y.6
Struhl, K.7
-
25
-
-
0037179716
-
Active genes are tri-methylated at K4 of histone H3
-
H. Santos-Rosa, R. Schneider, A.J. Bannister, J. Sherriff, B.E. Bernstein, N.C. Emre, S.L. Schreiber, J. Mellor, and T. Kouzarides Active genes are tri-methylated at K4 of histone H3 Nature 419 2002 407 411
-
(2002)
Nature
, vol.419
, pp. 407-411
-
-
Santos-Rosa, H.1
Schneider, R.2
Bannister, A.J.3
Sherriff, J.4
Bernstein, B.E.5
Emre, N.C.6
Schreiber, S.L.7
Mellor, J.8
Kouzarides, T.9
-
26
-
-
0028079924
-
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells
-
G. Sauvageau, P.M. Lansdorp, C.J. Eaves, D.E. Hogge, W.H. Dragowska, D.S. Reid, C. Largman, H.J. Lawrence, and R.K. Humphries Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells Proc. Natl. Acad. Sci. USA 91 1994 12223 12227
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 12223-12227
-
-
Sauvageau, G.1
Lansdorp, P.M.2
Eaves, C.J.3
Hogge, D.E.4
Dragowska, W.H.5
Reid, D.S.6
Largman, C.7
Lawrence, H.J.8
Humphries, R.K.9
-
28
-
-
0037438589
-
Common mechanism for oncogenic activation of MLL by forkhead family proteins
-
C.W. So, and M.L. Cleary Common mechanism for oncogenic activation of MLL by forkhead family proteins Blood 101 2003 633 639
-
(2003)
Blood
, vol.101
, pp. 633-639
-
-
So, C.W.1
Cleary, M.L.2
-
29
-
-
0034610814
-
The language of covalent histone modifications
-
B.D. Strahl, and C.D. Allis The language of covalent histone modifications Nature 403 2000 41 45
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
30
-
-
0037077178
-
Dot1p modulates silencing in yeast by methylation of the nucleosome core
-
F. van Leeuwen, P.R. Gafken, and D.E. Gottschling Dot1p modulates silencing in yeast by methylation of the nucleosome core Cell 109 2002 745 756
-
(2002)
Cell
, vol.109
, pp. 745-756
-
-
Van Leeuwen, F.1
Gafken, P.R.2
Gottschling, D.E.3
-
31
-
-
18644382388
-
The polycomb group protein EZH2 is involved in progression of prostate cancer
-
S. Varambally, S.M. Dhanasekaran, M. Zhou, T.R. Barrette, C. Kumar-Sinha, M.G. Sanda, D. Ghosh, K.J. Pienta, R.G. Sewalt, and A.P. Otte The polycomb group protein EZH2 is involved in progression of prostate cancer Nature 419 2002, 624 629
-
(2002)
Nature
, vol.419
, pp. 624-629
-
-
Varambally, S.1
Dhanasekaran, S.M.2
Zhou, M.3
Barrette, T.R.4
Kumar-Sinha, C.5
Sanda, M.G.6
Ghosh, D.7
Pienta, K.J.8
Sewalt, R.G.9
Otte, A.P.10
-
32
-
-
0037111567
-
Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties
-
A. Yokoyama, I. Kitabayashi, P.M. Ayton, M.L. Cleary, and M. Ohki Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties Blood 100 2002 3710 3718
-
(2002)
Blood
, vol.100
, pp. 3710-3718
-
-
Yokoyama, A.1
Kitabayashi, I.2
Ayton, P.M.3
Cleary, M.L.4
Ohki, M.5
-
33
-
-
2942715029
-
Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression
-
A. Yokoyama, Z. Wang, J. Wysocka, M. Sanyal, D.J. Aufiero, I. Kitabayashi, W. Herr, and M.L. Cleary Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression Mol. Cell. Biol. 24 2004 5639 5649
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5639-5649
-
-
Yokoyama, A.1
Wang, Z.2
Wysocka, J.3
Sanyal, M.4
Aufiero, D.J.5
Kitabayashi, I.6
Herr, W.7
Cleary, M.L.8
-
34
-
-
0035883954
-
Transcription regulation by histone methylation: Interplay between different covalent modifications of the core histone tails
-
Y. Zhang, and D. Reinberg Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails Genes Dev. 15 2001 2343 2360
-
(2001)
Genes Dev.
, vol.15
, pp. 2343-2360
-
-
Zhang, Y.1
Reinberg, D.2
-
35
-
-
1242269799
-
Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase
-
W. Zhang, Y. Hayashizaki, and B.C. Kone Structure and regulation of the mDot1 gene, a mouse histone H3 methyltransferase Biochem. J. 377 2004 641 651
-
(2004)
Biochem. J.
, vol.377
, pp. 641-651
-
-
Zhang, W.1
Hayashizaki, Y.2
Kone, B.C.3
|