A rationale to target the SWI/SNF complex for cancer therapy

Trends in Genetics

Volumn 30, Issue 8, 2014, Pages 356-363

  Hohmann, Anja F ^a   Vakoc, Christopher R ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

Cancer therapy; SWI SNF; Synthetic lethality

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BRG1 PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN SWI; TRANSCRIPTION FACTOR SNF; ANTINEOPLASTIC AGENT; NONHISTONE PROTEIN; SWI-SNF-B CHROMATIN-REMODELING COMPLEX; TRANSCRIPTION FACTOR;

ACUTE LEUKEMIA; CANCER THERAPY; CARCINOGENESIS; CELL DIFFERENTIATION; CELL VIABILITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; COLONY FORMATION; ENHANCER REGION; GENE CONTROL; GENE MUTATION; HUMAN; LUNG SMALL CELL CANCER; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TARGETING; REVIEW; TUMOR GROWTH; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG DESIGN; METABOLISM; NEOPLASMS;

ANIMALS; ANTINEOPLASTIC AGENTS; CHROMOSOMAL PROTEINS, NON-HISTONE; DRUG DESIGN; HUMANS; NEOPLASMS; TRANSCRIPTION FACTORS;

EID: 84904762312     PISSN: 01689525     EISSN: 13624555     Source Type: Journal    
DOI: 10.1016/j.tig.2014.05.001     Document Type: Review

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