ARID1B is a specific vulnerability in ARID1A-mutant cancers

Nature Medicine

Volumn 20, Issue 3, 2014, Pages 251-254

  Helming, Katherine C ^a,b,c   Wang, Xiaofeng ^a,b,c   Wilson, Boris G ^a,b,c   Vazquez, Francisca ^a,d   Haswell, Jeffrey R ^a,b,c   Manchester, Haley E ^a,b,c   Kim, Youngha ^a,b,c   Kryukov, Gregory V ^d   Ghandi, Mahmoud ^d   Aguirre, Andrew J ^a,d   Jagani, Zainab ^e   Wang, Zhong ^f   Garraway, Levi A ^a,d   Hahn, William C ^a,d   Roberts, Charles W M ^a,b,c,d  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARID1A PROTEIN; ARID1B PROTEIN; RETINOBLASTOMA BINDING PROTEIN 2; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CANCER CELL; CANCER SUSCEPTIBILITY; CELL SURVIVAL; CONTROLLED STUDY; GENE; GENE PRODUCT; HUMAN; HUMAN CELL; NEOPLASM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION;

ALLELES; ANIMALS; CELL LINE; CELL NUCLEUS; CELL PROLIFERATION; CHROMATIN; DNA-BINDING PROTEINS; FALSE POSITIVE REACTIONS; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HEK293 CELLS; HUMANS; MICE; MUTATION; NEOPLASMS; NUCLEAR PROTEINS; RNA, SMALL INTERFERING; TIME FACTORS; TRANSCRIPTION FACTORS;

EID: 84896126029     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3480     Document Type: Article

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