MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1

Cancer Discovery

Volumn 4, Issue 3, 2014, Pages 293-303

  Romero, Octavio A ^a   Torres Diz, Manuel ^a   Pros, Eva ^a   Savola, Suvi ^f   Gomez, Antonio ^a   Moran, Sebastian ^a   Saez, Carmen ^c,d   Iwakawa, Reika ^g   Villanueva, Alberto ^b   Montuenga, Luis M ^e   Kohno, Takashi ^g   Yokota, Jun ^g   Sanchez Cespedes, Montse ^a  

^a Genes and Cancer Group   (Spain)

^b HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^c Instituto de Biomedicina de Sevilla   (Spain)

^d UNIVERSITY OF SEVILLE   (Spain)

^e UNIVERSITY OF NAVARRA   (Spain)

^f MRC HOLLAND   (Netherlands)

^g NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC HELIX LOOP HELIX LEUCINE ZIPPER TRANSCRIPTION FACTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; BRG1 PROTEIN; DEXAMETHASONE; DNA HELICASE; MAX PROTEIN; MAX PROTEIN, HUMAN; MGA PROTEIN, HUMAN; NUCLEAR PROTEIN; PEPTIDES AND PROTEINS; SMARCA4 PROTEIN, HUMAN; SWITCH SUCROSE NONFERMENTABLE COMPLEX; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CONTROLLED STUDY; DNA EXTRACTION; DNA SEQUENCE; GENE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE MUTATION; GENETICS; GENOTYPE; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; LUNG TUMOR; METABOLISM; MICROARRAY ANALYSIS; MUTATION; MYC ASSOCIATED FACTOR X GENE; ONCOGENE MYC; PATHOLOGY; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; TUMOR CELL LINE; UPREGULATION; WESTERN BLOTTING;

BASIC HELIX-LOOP-HELIX LEUCINE ZIPPER TRANSCRIPTION FACTORS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; DNA HELICASES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; GENETICS; HUMANS; LUNG NEOPLASMS; METABOLISM; MUTATION; NUCLEAR PROTEINS; PATHOLOGY; PROMOTER REGIONS, GENETIC; SMALL CELL LUNG CARCINOMA; TRANSCRIPTION FACTORS;

EID: 84895821044     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-13-0799     Document Type: Article

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