메뉴 건너뛰기




Volumn 13, Issue 1, 2015, Pages

Aging and DNA methylation

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

EID: 84928728856     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/s12915-015-0118-4     Document Type: Article
Times cited : (351)

References (95)
  • 2
    • 0016439429 scopus 로고
    • DNA modification mechanisms and gene activity during development
    • Holliday R, Pugh JE. DNA modification mechanisms and gene activity during development. Science. 1975;187:226-32.
    • (1975) Science , vol.187 , pp. 226-232
    • Holliday, R.1    Pugh, J.E.2
  • 3
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature. 1993;366:362-5.
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 4
    • 0026603943 scopus 로고
    • X-chromosome inactivation and cell memory
    • Riggs AD, Pfeifer GP. X-chromosome inactivation and cell memory. Trends Genet. 1992;8:169-74.
    • (1992) Trends Genet , vol.8 , pp. 169-174
    • Riggs, A.D.1    Pfeifer, G.P.2
  • 6
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton AM, Bird A. CpG islands and the regulation of transcription. Genes Dev. 2011;25:1010-22.
    • (2011) Genes Dev , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 7
    • 17944397700 scopus 로고
    • Nucleotide composition of DNA and RNA from somatic tissues of humpback salmon and its changes during spawning
    • Berdishev MT, Korotaev GK, Boiarskikh GV, Vanyushin BF. Nucleotide composition of DNA and RNA from somatic tissues of humpback salmon and its changes during spawning. Biokhimiia. 1967;38:988-93.
    • (1967) Biokhimiia , vol.38 , pp. 988-993
    • Berdishev, M.T.1    Korotaev, G.K.2    Boiarskikh, G.V.3    Vanyushin, B.F.4
  • 8
    • 0019423126 scopus 로고
    • Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction
    • Romanov GA, Vanyushin BF. Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction. Biochim Biophys Acta. 1981;653:204-18.
    • (1981) Biochim Biophys Acta , vol.653 , pp. 204-218
    • Romanov, G.A.1    Vanyushin, B.F.2
  • 9
    • 0023664725 scopus 로고
    • Genomic 5-methyldeoxycytidine decreases with age
    • Wilson VL, Smith RA, Ma S, Cutler RG. Genomic 5-methyldeoxycytidine decreases with age. J Biol Chem. 1987;262:9948-51.
    • (1987) J Biol Chem , vol.262 , pp. 9948-9951
    • Wilson, V.L.1    Smith, R.A.2    Ma, S.3    Cutler, R.G.4
  • 10
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not in immortal cells
    • Wilson VL, Jones PA. DNA methylation decreases in aging but not in immortal cells. Science. 1983;220:1055-7.
    • (1983) Science , vol.220 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 11
    • 0023125009 scopus 로고
    • The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation
    • Fairweather DS, Fox M, Margison GP. The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation. Exp Cell Res. 1987;168:153-9.
    • (1987) Exp Cell Res , vol.168 , pp. 153-159
    • Fairweather, D.S.1    Fox, M.2    Margison, G.P.3
  • 15
    • 84894088246 scopus 로고    scopus 로고
    • Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites
    • Florath I, Butterbach K, Müller H, Bewerunge-Hudler M, Brenner H. Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites. Hum Mol Genet. 2014;23:1186-201.
    • (2014) Hum Mol Genet , vol.23 , pp. 1186-1201
    • Florath, I.1    Butterbach, K.2    Müller, H.3    Bewerunge-Hudler, M.4    Brenner, H.5
  • 17
    • 84886111619 scopus 로고    scopus 로고
    • DNA methylation age of human tissues and cell types
    • Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14:R115.
    • (2013) Genome Biol , vol.14 , pp. R115
    • Horvath, S.1
  • 18
    • 84896718645 scopus 로고    scopus 로고
    • Aging of blood can be tracked by DNA methylation changes at just three CpG sites
    • Weidner CI, Lin Q, Koch CM, Eisele L, Beier F, Ziegler P, et al. Aging of blood can be tracked by DNA methylation changes at just three CpG sites. Genome Biol. 2014;15:R24.
    • (2014) Genome Biol , vol.15 , pp. R24
    • Weidner, C.I.1    Lin, Q.2    Koch, C.M.3    Eisele, L.4    Beier, F.5    Ziegler, P.6
  • 22
    • 84899152478 scopus 로고    scopus 로고
    • Air pollution and gene-specific methylation in the Normative Aging Study: association, effect modification, and mediation analysis
    • Bind M-A, Lepeule J, Zanobetti A, Gasparrini A, Baccarelli A, Coull BA, et al. Air pollution and gene-specific methylation in the Normative Aging Study: association, effect modification, and mediation analysis. Epigenetics. 2014;9:448-58.
    • (2014) Epigenetics , vol.9 , pp. 448-458
    • Bind, M.-A.1    Lepeule, J.2    Zanobetti, A.3    Gasparrini, A.4    Baccarelli, A.5    Coull, B.A.6
  • 24
    • 84905238318 scopus 로고    scopus 로고
    • Modulation of age- and cancer-associated DNA methylation change in the healthy colon by aspirin and lifestyle
    • dju161
    • Noreen F, Röösli M, Gaj P, Pietrzak J, Weis S, Urfer P, et al. Modulation of age- and cancer-associated DNA methylation change in the healthy colon by aspirin and lifestyle. J Natl Cancer Inst. 2014;106:dju161.
    • (2014) J Natl Cancer Inst , vol.106
    • Noreen, F.1    Röösli, M.2    Gaj, P.3    Pietrzak, J.4    Weis, S.5    Urfer, P.6
  • 25
    • 84897538815 scopus 로고    scopus 로고
    • Smoke related DNA methylation changes in the etiology of human disease
    • Besingi W, Johansson Å. Smoke related DNA methylation changes in the etiology of human disease. Hum Mol Genet. 2013;23:2290-7.
    • (2013) Hum Mol Genet , vol.23 , pp. 2290-2297
    • Besingi, W.1    Johansson, A.2
  • 27
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, Cuff J, et al. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 2006;125:315-26.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1    Mikkelsen, T.S.2    Xie, X.3    Kamal, M.4    Huebert, D.J.5    Cuff, J.6
  • 28
    • 33646882068 scopus 로고    scopus 로고
    • Polycomb complexes repress developmental regulators in murine embryonic stem cells
    • Boyer LA, Plath K, Zeitlinger J, Brambrink T, Medeiros LA, Lee TI, et al. Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature. 2006;441:349-53.
    • (2006) Nature , vol.441 , pp. 349-353
    • Boyer, L.A.1    Plath, K.2    Zeitlinger, J.3    Brambrink, T.4    Medeiros, L.A.5    Lee, T.I.6
  • 29
    • 33646870495 scopus 로고    scopus 로고
    • Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
    • Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev. 2006;20:1123-36.
    • (2006) Genes Dev , vol.20 , pp. 1123-1136
    • Bracken, A.P.1    Dietrich, N.2    Pasini, D.3    Hansen, K.H.4    Helin, K.5
  • 30
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell. 2006;125:301-13.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3    Guenther, M.G.4    Levine, S.S.5    Kumar, R.M.6
  • 31
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • Margueron R, Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature. 2011;469:343-9.
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 32
    • 77951947926 scopus 로고    scopus 로고
    • Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination
    • Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, Sproul D, et al. Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell. 2010;38:452-64.
    • (2010) Mol Cell , vol.38 , pp. 452-464
    • Eskeland, R.1    Leeb, M.2    Grimes, G.R.3    Kress, C.4    Boyle, S.5    Sproul, D.6
  • 33
    • 9444244427 scopus 로고    scopus 로고
    • Chromatin compaction by a Polycomb group protein complex
    • Francis NJ, Kingston RE, Woodcock CL. Chromatin compaction by a Polycomb group protein complex. Science. 2004;306:1574-7.
    • (2004) Science , vol.306 , pp. 1574-1577
    • Francis, N.J.1    Kingston, R.E.2    Woodcock, C.L.3
  • 34
    • 33748055105 scopus 로고    scopus 로고
    • MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells
    • Rauch T, Li H, Wu X, Pfeifer GP. MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells. Cancer Res. 2006;66:7939-47.
    • (2006) Cancer Res , vol.66 , pp. 7939-7947
    • Rauch, T.1    Li, H.2    Wu, X.3    Pfeifer, G.P.4
  • 35
    • 33846649587 scopus 로고    scopus 로고
    • Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
    • Schlesinger Y, Straussman R, Keshet I, Farkash S, Hecht M, Zimmerman J, et al. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet. 2007;39:232-6.
    • (2007) Nat Genet , vol.39 , pp. 232-236
    • Schlesinger, Y.1    Straussman, R.2    Keshet, I.3    Farkash, S.4    Hecht, M.5    Zimmerman, J.6
  • 36
    • 33846569960 scopus 로고    scopus 로고
    • A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
    • Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet. 2007;39:237-42.
    • (2007) Nat Genet , vol.39 , pp. 237-242
    • Ohm, J.E.1    McGarvey, K.M.2    Yu, X.3    Cheng, L.4    Schuebel, K.E.5    Cope, L.6
  • 38
    • 57749090255 scopus 로고    scopus 로고
    • Methylation of polycomb target genes in intestinal cancer is mediated by inflammation
    • Hahn MA, Hahn T, Lee D-H, Esworthy RS, Kim B-W, Riggs AD, et al. Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. Cancer Res. 2008;68:10280-9.
    • (2008) Cancer Res , vol.68 , pp. 10280-10289
    • Hahn, M.A.1    Hahn, T.2    Lee, D.-H.3    Esworthy, R.S.4    Kim, B.-W.5    Riggs, A.D.6
  • 39
    • 84880921962 scopus 로고    scopus 로고
    • The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells
    • Kalari S, Jung M, Kernstine KH, Takahashi T, Pfeifer GP. The DNA methylation landscape of small cell lung cancer suggests a differentiation defect of neuroendocrine cells. Oncogene. 2013;32:3559-68.
    • (2013) Oncogene , vol.32 , pp. 3559-3568
    • Kalari, S.1    Jung, M.2    Kernstine, K.H.3    Takahashi, T.4    Pfeifer, G.P.5
  • 40
    • 84892613108 scopus 로고    scopus 로고
    • Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation
    • Johnson KC, Koestler DC, Cheng C, Christensen BC. Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation. Epigenetics. 2014;9:268-75.
    • (2014) Epigenetics , vol.9 , pp. 268-275
    • Johnson, K.C.1    Koestler, D.C.2    Cheng, C.3    Christensen, B.C.4
  • 41
    • 84857190178 scopus 로고    scopus 로고
    • An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment
    • Lynch MD, Smith AJH, De Gobbi M, Flenley M, Hughes JR, Vernimmen D, et al. An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment. EMBO J. 2012;31:317-29.
    • (2012) EMBO J , vol.31 , pp. 317-329
    • Lynch, M.D.1    Smith, A.J.H.2    Gobbi, M.3    Flenley, M.4    Hughes, J.R.5    Vernimmen, D.6
  • 42
    • 77649240380 scopus 로고    scopus 로고
    • Widespread and tissue specific age-related DNA methylation changes in mice
    • Maegawa S, Hinkal G, Kim HS, Shen L, Zhang L, Zhang J, et al. Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res. 2010;20:332-40.
    • (2010) Genome Res , vol.20 , pp. 332-340
    • Maegawa, S.1    Hinkal, G.2    Kim, H.S.3    Shen, L.4    Zhang, L.5    Zhang, J.6
  • 44
    • 84902127230 scopus 로고    scopus 로고
    • Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and Polycomb domain formation
    • Blackledge NP, Farcas AM, Kondo T, King HW, McGouran JF, Hanssen LLP, et al. Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and Polycomb domain formation. Cell. 2014;157:1445-59.
    • (2014) Cell , vol.157 , pp. 1445-1459
    • Blackledge, N.P.1    Farcas, A.M.2    Kondo, T.3    King, H.W.4    McGouran, J.F.5    Hanssen, L.L.P.6
  • 45
    • 84861912630 scopus 로고    scopus 로고
    • Programming of DNA methylation patterns
    • Cedar H, Bergman Y. Programming of DNA methylation patterns. Annu Rev Biochem. 2012;81:97-117.
    • (2012) Annu Rev Biochem , vol.81 , pp. 97-117
    • Cedar, H.1    Bergman, Y.2
  • 46
    • 51349105905 scopus 로고    scopus 로고
    • Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
    • Gal-Yam EN, Egger G, Iniguez L, Holster H, Einarsson S, Zhang X, et al. Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc Natl Acad Sci U S A. 2008;105:12979-84.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 12979-12984
    • Gal-Yam, E.N.1    Egger, G.2    Iniguez, L.3    Holster, H.4    Einarsson, S.5    Zhang, X.6
  • 47
    • 34547941973 scopus 로고    scopus 로고
    • The common biology of cancer and ageing
    • Finkel T, Serrano M, Blasco MA. The common biology of cancer and ageing. Nature. 2007;448:767-74.
    • (2007) Nature , vol.448 , pp. 767-774
    • Finkel, T.1    Serrano, M.2    Blasco, M.A.3
  • 49
    • 84655162785 scopus 로고    scopus 로고
    • Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains
    • Berman BP, Weisenberger DJ, Aman JF, Hinoue T, Ramjan Z, Liu Y, et al. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nat Genet. 2012;44:40-6.
    • (2012) Nat Genet , vol.44 , pp. 40-46
    • Berman, B.P.1    Weisenberger, D.J.2    Aman, J.F.3    Hinoue, T.4    Ramjan, Z.5    Liu, Y.6
  • 50
    • 38049164130 scopus 로고    scopus 로고
    • Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice
    • Howard G, Eiges R, Gaudet F, Jaenisch R, Eden A. Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice. Oncogene. 2008;27:404-8.
    • (2008) Oncogene , vol.27 , pp. 404-408
    • Howard, G.1    Eiges, R.2    Gaudet, F.3    Jaenisch, R.4    Eden, A.5
  • 52
    • 0032559995 scopus 로고    scopus 로고
    • Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer
    • Fujii H, Biel MA, Zhou W, Weitzman SA, Baylin SB, Gabrielson E. Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer. Oncogene. 1998;16:2159-64.
    • (1998) Oncogene , vol.16 , pp. 2159-2164
    • Fujii, H.1    Biel, M.A.2    Zhou, W.3    Weitzman, S.A.4    Baylin, S.B.5    Gabrielson, E.6
  • 53
    • 46049116276 scopus 로고    scopus 로고
    • Reduction of GSTP1 expression by DNA methylation correlates with clinicopathological features in pituitary adenomas
    • Yuan Y, Qian ZR, Sano T, Asa SL, Yamada S, Kagawa N, et al. Reduction of GSTP1 expression by DNA methylation correlates with clinicopathological features in pituitary adenomas. Mod Pathol. 2008;21:856-65.
    • (2008) Mod Pathol , vol.21 , pp. 856-865
    • Yuan, Y.1    Qian, Z.R.2    Sano, T.3    Asa, S.L.4    Yamada, S.5    Kagawa, N.6    Kudo, E.7
  • 55
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet. 2000;25:315-9.
    • (2000) Nat Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3    Chin, P.L.4    Bates, S.5    Pfeifer, G.P.6
  • 56
    • 0032767550 scopus 로고    scopus 로고
    • Differential DNA methylation of the p16 INK4A/CDKN2A promoter in human oral cancer cells and normal human oral keratinocytes
    • Cody DT, Huang Y, Darby CJ, Johnson GK, Domann FE. Differential DNA methylation of the p16 INK4A/CDKN2A promoter in human oral cancer cells and normal human oral keratinocytes. Oral Oncol. 1999;35:516-22.
    • (1999) Oral Oncol , vol.35 , pp. 516-522
    • Cody, D.T.1    Huang, Y.2    Darby, C.J.3    Johnson, G.K.4    Domann, F.E.5
  • 57
    • 0034772312 scopus 로고    scopus 로고
    • Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas
    • Virmani AK, Rathi A, Sathyanarayana UG, Padar A, Huang CX, Cunnigham HT, et al. Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas. Clin Cancer Res. 2001;7:1998-2004.
    • (2001) Clin Cancer Res , vol.7 , pp. 1998-2004
    • Virmani, A.K.1    Rathi, A.2    Sathyanarayana, U.G.3    Padar, A.4    Huang, C.X.5    Cunnigham, H.T.6
  • 59
  • 60
    • 3142672297 scopus 로고    scopus 로고
    • DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E
    • Lund G, Andersson L, Lauria M, Lindholm M, Fraga MF, Villar-Garea A, et al. DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E. J Biol Chem. 2004;279:29147-54.
    • (2004) J Biol Chem , vol.279 , pp. 29147-29154
    • Lund, G.1    Andersson, L.2    Lauria, M.3    Lindholm, M.4    Fraga, M.F.5    Villar-Garea, A.6
  • 62
    • 84897452599 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion
    • Dayeh T, Volkov P, Salö S, Hall E, Nilsson E, Olsson AH, et al. Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion. PLoS Genet. 2014;10:e1004160.
    • (2014) PLoS Genet , vol.10 , pp. e1004160
    • Dayeh, T.1    Volkov, P.2    Salö, S.3    Hall, E.4    Nilsson, E.5    Olsson, A.H.6
  • 63
    • 0033052929 scopus 로고    scopus 로고
    • Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex
    • Tohgi H, Utsugisawa K, Nagane Y, Yoshimura M, Genda Y, Ukitsu M. Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex. Brain Res Mol Brain Res. 1999;70:288-92.
    • (1999) Brain Res Mol Brain Res , vol.70 , pp. 288-292
    • Tohgi, H.1    Utsugisawa, K.2    Nagane, Y.3    Yoshimura, M.4    Genda, Y.5    Ukitsu, M.6
  • 64
    • 10644237168 scopus 로고    scopus 로고
    • S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production
    • Fuso A, Seminara L, Cavallaro RA, D'Anselmi F, Scarpa S. S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production. Mol Cell Neurosci. 2005;28:195-204.
    • (2005) Mol Cell Neurosci , vol.28 , pp. 195-204
    • Fuso, A.1    Seminara, L.2    Cavallaro, R.A.3    D'Anselmi, F.4    Scarpa, S.5
  • 65
    • 34447642134 scopus 로고    scopus 로고
    • gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells
    • Fuso A, Cavallaro RA, Zampelli A, D'Anselmi F, Piscopo P, Confaloni A, et al. gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells. J Alzheimers Dis. 2007;11:275-90.
    • (2007) J Alzheimers Dis , vol.11 , pp. 275-290
    • Fuso, A.1    Cavallaro, R.A.2    Zampelli, A.3    D'Anselmi, F.4    Piscopo, P.5    Confaloni, A.6    Scarpa, S.7
  • 66
    • 84898832764 scopus 로고    scopus 로고
    • "IDEAL" aging Is associated with lower resting metabolic rate: The Baltimore Longitudinal Study of Aging
    • Schrack JA, Knuth ND, Simonsick EM, Ferrucci L. "IDEAL" aging Is associated with lower resting metabolic rate: The Baltimore Longitudinal Study of Aging. J Am Geriatr Soc. 2014;62:667-72.
    • (2014) J Am Geriatr Soc , vol.62 , pp. 667-672
    • Schrack, J.A.1    Knuth, N.D.2    Simonsick, E.M.3    Ferrucci, L.4
  • 67
    • 0037370532 scopus 로고    scopus 로고
    • Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism
    • Mason JB. Biomarkers of nutrient exposure and status in one-carbon (methyl) metabolism. J Nutr. 2003;133:941S-7S.
    • (2003) J Nutr , vol.133 , pp. 941S-947S
    • Mason, J.B.1
  • 70
    • 0036326660 scopus 로고    scopus 로고
    • Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology
    • James SJ, Melnyk S, Pogribna M, Pogribny IP, Caudill MA. Elevation in S-adenosylhomocysteine and DNA hypomethylation: potential epigenetic mechanism for homocysteine-related pathology. J Nutr. 2002;132:2361S-6S.
    • (2002) J Nutr , vol.132 , pp. 2361S-2366S
    • James, S.J.1    Melnyk, S.2    Pogribna, M.3    Pogribny, I.P.4    Caudill, M.A.5
  • 73
    • 84899155341 scopus 로고    scopus 로고
    • Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort
    • Bae S, Ulrich CM, Bailey LB, Malysheva O, Brown EC, Maneval DR, et al. Impact of folic acid fortification on global DNA methylation and one-carbon biomarkers in the Women's Health Initiative Observational Study cohort. Epigenetics. 2014;9:396-403.
    • (2014) Epigenetics , vol.9 , pp. 396-403
    • Bae, S.1    Ulrich, C.M.2    Bailey, L.B.3    Malysheva, O.4    Brown, E.C.5    Maneval, D.R.6
  • 76
    • 79959990071 scopus 로고    scopus 로고
    • Regulation of mammalian DNA methyltransferases: a route to new mechanisms
    • Denis H, Ndlovu 'Matladi N, Fuks F. Regulation of mammalian DNA methyltransferases: a route to new mechanisms. EMBO Rep. 2011;12:647-56.
    • (2011) EMBO Rep , vol.12 , pp. 647-656
    • Denis, H.1    Ndlovu 'Matladi, N.2    Fuks, F.3
  • 77
    • 0033753779 scopus 로고    scopus 로고
    • The DNA, methyltransferases of mammals
    • Bestor TH. The DNA, methyltransferases of mammals. Hum Mol Genet. 2000;9:2395-402.
    • (2000) Hum Mol Genet , vol.9 , pp. 2395-2402
    • Bestor, T.H.1
  • 78
    • 0141839825 scopus 로고    scopus 로고
    • Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
    • Casillas Jr MA, Lopatina N, Andrews LG, Tollefsbol TO. Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts. Mol Cell Biochem. 2003;252:33-43.
    • (2003) Mol Cell Biochem , vol.252 , pp. 33-43
    • Casillas, M.A.1    Lopatina, N.2    Andrews, L.G.3    Tollefsbol, T.O.4
  • 79
    • 0035679346 scopus 로고    scopus 로고
    • Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts
    • Lopatina N, Haskell JF, Andrews LG, Poole JC, Saldanha S, Tollefsbol T. Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts. J Cell Biochem. 2002;84:324-34.
    • (2002) J Cell Biochem , vol.84 , pp. 324-334
    • Lopatina, N.1    Haskell, J.F.2    Andrews, L.G.3    Poole, J.C.4    Saldanha, S.5    Tollefsbol, T.6
  • 80
    • 84863012853 scopus 로고    scopus 로고
    • Insufficient DNA methylation affects healthy aging and promotes age-related health problems
    • Liu L, van Groen T, Kadish I, Li Y, Wang D, James SR, et al. Insufficient DNA methylation affects healthy aging and promotes age-related health problems. Clin Epigenetics. 2011;2:349-60.
    • (2011) Clin Epigenetics , vol.2 , pp. 349-360
    • Liu, L.1    Groen, T.2    Kadish, I.3    Li, Y.4    Wang, D.5    James, S.R.6
  • 81
    • 84904022275 scopus 로고    scopus 로고
    • Expression of DNA methyltransferases is influenced by growth hormone in the long-living ames dwarf mouse in vivo and in vitro
    • Armstrong VL, Rakoczy S, Rojanathammanee L, Brown-Borg HM. Expression of DNA methyltransferases is influenced by growth hormone in the long-living ames dwarf mouse in vivo and in vitro. J Gerontol A Biol Sci Med Sci. 2014;69:923-33.
    • (2014) J Gerontol A Biol Sci Med Sci , vol.69 , pp. 923-933
    • Armstrong, V.L.1    Rakoczy, S.2    Rojanathammanee, L.3    Brown-Borg, H.M.4
  • 82
    • 84874252793 scopus 로고    scopus 로고
    • Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis
    • Hahn MA, Qiu R, Wu X, Li AX, Zhang H, Wang J, et al. Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Rep. 2013;3:291-300.
    • (2013) Cell Rep , vol.3 , pp. 291-300
    • Hahn, M.A.1    Qiu, R.2    Wu, X.3    Li, A.X.4    Zhang, H.5    Wang, J.6
  • 83
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
    • Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science. 2009;324:930-5.
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3    Pastor, W.A.4    Bandukwala, H.5    Brudno, Y.6
  • 84
    • 84860749868 scopus 로고    scopus 로고
    • Tet family proteins and 5-hydroxymethylcytosine in development and disease
    • Tan L, Shi YG. Tet family proteins and 5-hydroxymethylcytosine in development and disease. Development. 2012;139:1895-902.
    • (2012) Development , vol.139 , pp. 1895-1902
    • Tan, L.1    Shi, Y.G.2
  • 86
    • 0142185046 scopus 로고    scopus 로고
    • Age-related epigenetic changes and the immune system
    • Issa J-P. Age-related epigenetic changes and the immune system. Clin Immunol. 2003;109:103-8.
    • (2003) Clin Immunol , vol.109 , pp. 103-108
    • Issa, J.-P.1
  • 87
    • 84883727941 scopus 로고    scopus 로고
    • Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape
    • Day K, Waite LL, Thalacker-Mercer A, West A, Bamman MM, Brooks JD, et al. Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape. Genome Biol. 2013;14:R102.
    • (2013) Genome Biol , vol.14 , pp. R102
    • Day, K.1    Waite, L.L.2    Thalacker-Mercer, A.3    West, A.4    Bamman, M.M.5    Brooks, J.D.6
  • 88
    • 84872806231 scopus 로고    scopus 로고
    • Genome-wide methylation profiles reveal quantitative views of human aging rates
    • Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell. 2013;49:359-67.
    • (2013) Mol Cell , vol.49 , pp. 359-367
    • Hannum, G.1    Guinney, J.2    Zhao, L.3    Zhang, L.4    Hughes, G.5    Sadda, S.6
  • 89
    • 79960375714 scopus 로고    scopus 로고
    • Epigenetic regulation of aging stem cells
    • Pollina EA, Brunet A. Epigenetic regulation of aging stem cells. Oncogene. 2011;30:3105-26.
    • (2011) Oncogene , vol.30 , pp. 3105-3126
    • Pollina, E.A.1    Brunet, A.2
  • 90
    • 70350654370 scopus 로고    scopus 로고
    • DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
    • Bröske A-M, Vockentanz L, Kharazi S, Huska MR, Mancini E, Scheller M, et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nat Genet. 2009;41:1207-15.
    • (2009) Nat Genet , vol.41 , pp. 1207-1215
    • Bröske, A.-M.1    Vockentanz, L.2    Kharazi, S.3    Huska, M.R.4    Mancini, E.5    Scheller, M.6
  • 91
    • 84875965163 scopus 로고    scopus 로고
    • Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging
    • Beerman I, Bock C, Garrison BS, Smith ZD, Gu H, Meissner A, et al. Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging. Cell Stem Cell. 2013;12:413-25.
    • (2013) Cell Stem Cell , vol.12 , pp. 413-425
    • Beerman, I.1    Bock, C.2    Garrison, B.S.3    Smith, Z.D.4    Gu, H.5    Meissner, A.6    Rossi, D.J.7
  • 92
    • 84899768899 scopus 로고    scopus 로고
    • Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal
    • Sun D, Luo M, Jeong M, Rodriguez B, Xia Z, Hannah R, et al. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell. 2014;14:673-88.
    • (2014) Cell Stem Cell , vol.14 , pp. 673-688
    • Sun, D.1    Luo, M.2    Jeong, M.3    Rodriguez, B.4    Xia, Z.5    Hannah, R.6
  • 93
    • 34547725157 scopus 로고    scopus 로고
    • DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
    • Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature. 2007;448:714-7.
    • (2007) Nature , vol.448 , pp. 714-717
    • Ooi, S.K.1    Qiu, C.2    Bernstein, E.3    Li, K.4    Jia, D.5    Yang, Z.6
  • 94
    • 78249271058 scopus 로고    scopus 로고
    • Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease
    • Osorio FG, Varela I, Lara E, Puente XS, Espada J, Santoro R, et al. Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloprotease. Aging Cell. 2010;9:947-57.
    • (2010) Aging Cell , vol.9 , pp. 947-957
    • Osorio, F.G.1    Varela, I.2    Lara, E.3    Puente, X.S.4    Espada, J.5    Santoro, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.