Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma

Nature Medicine

Volumn 20, Issue 12, 2014, Pages 1394-1396

  Hashizume, Rintaro ^a   Andor, Noemi ^b   Ihara, Yuichiro ^b   Lerner, Robin ^b   Gan, Haiyun ^c   Chen, Xiaoyue ^c   Fang, Dong ^c   Huang, Xi ^d   Tom, Maxwell W ^b   Ngo, Vy ^d   Solomon, David ^b,e   Mueller, Sabine ^b   Paris, Pamela L ^d   Zhang, Zhiguo ^c   Petritsch, Claudia ^b   Gupta, Nalin ^b   Waldman, Todd A ^e   James, C David ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MAYO GRADUATE SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e GEORGETOWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZAZEPINE DERIVATIVE; GSK-J4; HISTONE; HISTONE DEMETHYLASE; KDM6B PROTEIN, HUMAN; PYRIMIDINE DERIVATIVE;

ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; BRAIN STEM TUMOR; CELL PROLIFERATION; CHILD; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; HUMAN; METABOLISM; METHYLATION; MOUSE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BENZAZEPINES; BRAIN STEM NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHILD; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HISTONES; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; METHYLATION; MICE; PYRIMIDINES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84961291627     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3716     Document Type: Article

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