The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas

Science

Volumn 352, Issue 6291, 2016, Pages 1344-1348

  Fang, Dong ^a   Gan, Haiyun ^a   Lee, Jeong Heon ^a,b   Han, Jing ^a   Wang, Zhiquan ^a   Riester, Scott M ^b   Jin, Long ^b   Chen, Jianji ^c   Zhou, Hui ^a   Wang, Jinglong ^d,e   Zhang, Honglian ^a   Yang, Na ^d   Bradley, Elizabeth W ^b   Ho, Thai H ^f   Rubin, Brian P ^g   Bridge, Julia A ^h   Thibodeau, Stephen N ^b   Ordog, Tamas ^b,i,j   Chen, Yue ^c   Van Wijnen, Andre J ^a,b   Oliveira, Andre M ^b   Xu, Rui Ming ^d,e   Westendorf, Jennifer J ^a,b   Zhang, Zhiguo ^a,b   more..

^a MAYO GRADUATE SCHOOL   (United States)

^b Mayo Clinic   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d INSTITUTE OF BIOPHYSICS   (China)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^f MAYO CLINIC   (United States)

^g LERNER RESEARCH INSTITUTE   (United States)

^h Pediatrics   (United States)

ⁱ MAYO CLINIC   (United States)

^j UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; METHYLTRANSFERASE; SPACER DNA; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; LYSINE; REPRESSOR PROTEIN; SET2 PROTEIN, HUMAN; WHSC1 PROTEIN, HUMAN;

CANCER; CELLS AND CELL COMPONENTS; ENZYME; ENZYME ACTIVITY; GENOMICS; INHIBITION; METHYLATION; MUTATION; PROTEIN;

APOPTOSIS; ARTICLE; BONE TISSUE; CANCER RESISTANCE; CARCINOGENESIS; CARTILAGE CELL; CHONDROBLASTOMA; CHROMATIN IMMUNOPRECIPITATION; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; EPIGENETICS; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENE MUTATION; GIANT CELL TUMOR; HISTONE METHYLATION; HUMAN; IC50; IMMUNOFLUORESCENCE; NEXT GENERATION SEQUENCING; NUCLEAR REPROGRAMMING; PRIORITY JOURNAL; PROMOTER REGION; WESTERN BLOTTING; AMINO ACID SUBSTITUTION; BONE TUMOR; GENETIC EPIGENESIS; GENETICS; METABOLISM; METHYLATION; MUTATION; TUMOR GENE;

AMINO ACID SUBSTITUTION; BONE NEOPLASMS; CARCINOGENESIS; CHONDROBLASTOMA; EPIGENESIS, GENETIC; GENES, NEOPLASM; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; LYSINE; METHYLATION; MUTATION; REPRESSOR PROTEINS;

EID: 84975138875     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aae0065     Document Type: Article

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