-
1
-
-
25144440127
-
Rational development of histone deacetylase inhibitors as anticancer agents: A review
-
Acharya, M.R., Sparreboom, A., Venitz, J. Figg, W.D. (2005) Rational development of histone deacetylase inhibitors as anticancer agents: a review. Molecular Pharmacology, 68, 917 932.
-
(2005)
Molecular Pharmacology
, vol.68
, pp. 917-932
-
-
Acharya, M.R.1
Sparreboom, A.2
Venitz, J.3
Figg, W.D.4
-
2
-
-
64049094851
-
Epigenetic therapies in haematological malignancies: Searching for true targets
-
Altucci, L. Minucci, S. (2009) Epigenetic therapies in haematological malignancies: searching for true targets. European Journal of Cancer, 45, 1137 1145.
-
(2009)
European Journal of Cancer
, vol.45
, pp. 1137-1145
-
-
Altucci, L.1
Minucci, S.2
-
3
-
-
10944224581
-
Cytoplasmic sequestration of HDAC7 from mitochondrial and nuclear compartments upon initiation of apoptosis
-
Bakin, R.E. Jung, M.O. (2004) Cytoplasmic sequestration of HDAC7 from mitochondrial and nuclear compartments upon initiation of apoptosis. Journal of Biological Chemistry, 279, 51218 51225.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 51218-51225
-
-
Bakin, R.E.1
Jung, M.O.2
-
4
-
-
33644846509
-
Epigenetic gene silencing in cancer - A mechanism for early oncogenic pathway addiction?
-
Baylin, S.B. Ohm, J.E. (2006) Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nature Reviews. Cancer, 6, 107 116.
-
(2006)
Nature Reviews. Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
5
-
-
33847032960
-
The mammalian epigenome
-
Bernstein, B.E., Meissner, A. Lander, E.S. (2007) The mammalian epigenome. Cell, 128, 669 681.
-
(2007)
Cell
, vol.128
, pp. 669-681
-
-
Bernstein, B.E.1
Meissner, A.2
Lander, E.S.3
-
6
-
-
70350448445
-
Phase II study of the histone deacetylase inhibitor MGCD0103 in patients with previously treated chronic lymphocytic leukaemia
-
Blum, K.A., Advani, A., Fernandez, L., Van Der Jagt, R., Brandwein, J., Kambhampati, S., Kassis, J., Davis, M., Bonfils, C., Dubay, M., Dumouchel, J., Drouin, M., Lucas, D.M., Martell, R.E. Byrd, J.C. (2009) Phase II study of the histone deacetylase inhibitor MGCD0103 in patients with previously treated chronic lymphocytic leukaemia. British Journal Haematology, 147, 507 514.
-
(2009)
British Journal Haematology
, vol.147
, pp. 507-514
-
-
Blum, K.A.1
Advani, A.2
Fernandez, L.3
Van Der Jagt, R.4
Brandwein, J.5
Kambhampati, S.6
Kassis, J.7
Davis, M.8
Bonfils, C.9
Dubay, M.10
Dumouchel, J.11
Drouin, M.12
Lucas, D.M.13
Martell, R.E.14
Byrd, J.C.15
-
7
-
-
27144475816
-
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
-
Bradbury, C.A., Khanim, F.L., Hayden, R., Bunce, C.M., White, D.A., Drayson, M.T., Craddock, C. Turner, B.M. (2005) Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors. Leukemia, 19, 1751 1759.
-
(2005)
Leukemia
, vol.19
, pp. 1751-1759
-
-
Bradbury, C.A.1
Khanim, F.L.2
Hayden, R.3
Bunce, C.M.4
White, D.A.5
Drayson, M.T.6
Craddock, C.7
Turner, B.M.8
-
8
-
-
77951651730
-
Benefits of the intermittent use of 6-mercaptopurine and methotrexate in maintenance treatment for low-risk acute lymphoblastic leukemia in children: Randomized trial from the Brazilian Childhood Cooperative Group - Protocol ALL-99
-
in press. doi/10.1200/JCO.2009.25.6115.
-
Brandalise, S.R., Pinheiro, V.R., Aguiar, S.S., Matsuda, E.I., Otubo, R., Yunes, J.A., Pereira, W.V., Carvalho, E.G., Cristofani, L.M., Souza, M.S., Lee, M.L., Dobbin, J.A., Pombo-de-Oliveira, M.S., Lopes, L.F., Melnikoff, K.N., Brunetto, A.L., Tone, L.G., Scrideli, C.A., Morais, V.L. Viana, M.B. (2010) Benefits of the intermittent use of 6-mercaptopurine and methotrexate in maintenance treatment for low-risk acute lymphoblastic leukemia in children: randomized trial from the Brazilian Childhood Cooperative Group - Protocol ALL-99. Journal of Clinical Oncology, in press, doi/10.1200/JCO.2009.25.6115.
-
(2010)
Journal of Clinical Oncology
-
-
Brandalise, S.R.1
Pinheiro, V.R.2
Aguiar, S.S.3
Matsuda, E.I.4
Otubo, R.5
Yunes, J.A.6
Pereira, W.V.7
Carvalho, E.G.8
Cristofani, L.M.9
Souza, M.S.10
Lee, M.L.11
Dobbin, J.A.12
Pombo-De-Oliveira, M.S.13
Lopes, L.F.14
Melnikoff, K.N.15
Brunetto, A.L.16
Tone, L.G.17
Scrideli, C.A.18
Morais, V.L.19
Viana, M.B.20
more..
-
9
-
-
19944432566
-
A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia
-
Byrd, J.C., Marcucci, G., Parthun, M.R., Xiao, J.J., Klisovic, R.B., Moran, M., Lin, T.S., Liu, S., Sklenar, A.R., Davis, M.E., Lucas, D.M., Fischer, B., Shank, R., Tejaswi, S.L., Binkley, P., Wright, J., Chan, K.K. Grever, M.R. (2005) A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia. Blood, 105, 959 967.
-
(2005)
Blood
, vol.105
, pp. 959-967
-
-
Byrd, J.C.1
Marcucci, G.2
Parthun, M.R.3
Xiao, J.J.4
Klisovic, R.B.5
Moran, M.6
Lin, T.S.7
Liu, S.8
Sklenar, A.R.9
Davis, M.E.10
Lucas, D.M.11
Fischer, B.12
Shank, R.13
Tejaswi, S.L.14
Binkley, P.15
Wright, J.16
Chan, K.K.17
Grever, M.R.18
-
10
-
-
34248330345
-
Gene expression profiles in squamous cell cervical carcinoma using array-based comparative genomic hybridization analysis
-
Choi, Y.W., Bae, S.M., Kim, Y.W., Lee, H.N., Kim, Y.W., Park, T.C., Ro, D.Y., Shin, J.C., Shin, S.J., Seo, J.S. Ahn, W.S. (2007) Gene expression profiles in squamous cell cervical carcinoma using array-based comparative genomic hybridization analysis. International Journal Of Gynecological Cancer, 17, 687 696.
-
(2007)
International Journal of Gynecological Cancer
, vol.17
, pp. 687-696
-
-
Choi, Y.W.1
Bae, S.M.2
Kim, Y.W.3
Lee, H.N.4
Kim, Y.W.5
Park, T.C.6
Ro, D.Y.7
Shin, J.C.8
Shin, S.J.9
Seo, J.S.10
Ahn, W.S.11
-
11
-
-
71049164788
-
MRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death
-
Cortez, M.A., Scrideli, C.A., Yunes, J.A., Valera, E.T., Toledo, S.R., Pavoni-Ferreira, P.C., Lee, M.L., Petrilli, A.S., Brandalise, S.R. Tone, L.G. (2009) mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death. Pediatric Blood & Cancer, 53, 996 1004.
-
(2009)
Pediatric Blood & Cancer
, vol.53
, pp. 996-1004
-
-
Cortez, M.A.1
Scrideli, C.A.2
Yunes, J.A.3
Valera, E.T.4
Toledo, S.R.5
Pavoni-Ferreira, P.C.6
Lee, M.L.7
Petrilli, A.S.8
Brandalise, S.R.9
Tone, L.G.10
-
12
-
-
0034045040
-
Histone deacetylases, transcriptional control, and cancer
-
Cress, W.D. Seto, E. (2000) Histone deacetylases, transcriptional control, and cancer. Journal of Cellular Physiology, 184, 1 16.
-
(2000)
Journal of Cellular Physiology
, vol.184
, pp. 1-16
-
-
Cress, W.D.1
Seto, E.2
-
13
-
-
33845211776
-
Epigenetic aberrations and cancer
-
Ducasse, M. Brown, M.A. (2006) Epigenetic aberrations and cancer. Molecular Cancer, 5, 60.
-
(2006)
Molecular Cancer
, vol.5
, pp. 60
-
-
Ducasse, M.1
Brown, M.A.2
-
14
-
-
0035914741
-
Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells
-
Esau, C., Boes, M., Youn, H.D., Tatterson, L., Liu, J.O. Chen, J. (2001) Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells. Journal of Experimental Medicine, 194, 1449 1459.
-
(2001)
Journal of Experimental Medicine
, vol.194
, pp. 1449-1459
-
-
Esau, C.1
Boes, M.2
Youn, H.D.3
Tatterson, L.4
Liu, J.O.5
Chen, J.6
-
15
-
-
33947313218
-
HDACs, histone deacetylation and gene transcription: From molecular biology to cancer therapeutics
-
Gallinari, P., Di Marco, S., Jones, P., Pallaoro, M. Steinkuhler, C. (2007) HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics. Cell Research, 17, 195 211.
-
(2007)
Cell Research
, vol.17
, pp. 195-211
-
-
Gallinari, P.1
Di Marco, S.2
Jones, P.3
Pallaoro, M.4
Steinkuhler, C.5
-
16
-
-
30844462355
-
The fundamental role of epigenetics in hematopoietic malignancies
-
Galm, O., Herman, J.G. Baylin, S.B. (2006) The fundamental role of epigenetics in hematopoietic malignancies. Blood Reviews, 20, 1 13.
-
(2006)
Blood Reviews
, vol.20
, pp. 1-13
-
-
Galm, O.1
Herman, J.G.2
Baylin, S.B.3
-
17
-
-
51649110503
-
Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia
-
Garcia-Manero, G., Assouline, S., Cortes, J., Estrov, Z., Kantarjian, H., Yang, H., Newsome, W.M., Miller, Jr., W.H., Rousseau, C., Kalita, A., Bonfils, C., Dubay, M., Patterson, T.A., Li, Z., Besterman, J.M., Reid, G., Laille, E., Martell, R.E. Minden, M. (2008) Phase 1 study of the oral isotype specific histone deacetylase inhibitor MGCD0103 in leukemia. Blood, 112, 981 989.
-
(2008)
Blood
, vol.112
, pp. 981-989
-
-
Garcia-Manero, G.1
Assouline, S.2
Cortes, J.3
Estrov, Z.4
Kantarjian, H.5
Yang, H.6
Newsome, W.M.7
Miller Jr., W.H.8
Rousseau, C.9
Kalita, A.10
Bonfils, C.11
Dubay, M.12
Patterson, T.A.13
Li, Z.14
Besterman, J.M.15
Reid, G.16
Laille, E.17
Martell, R.E.18
Minden, M.19
-
18
-
-
70350451749
-
Expression of histone deacetylases in lymphoma: Implication for the development of selective inhibitors
-
Gloghini, A., Buglio, D., Khaskhely, N.M., Georgakis, G., Orlowski, R.Z., Neelapu, S.S., Carbone, A. Younes, A. (2009) Expression of histone deacetylases in lymphoma: implication for the development of selective inhibitors. British Journal Haematology, 147, 515 525.
-
(2009)
British Journal Haematology
, vol.147
, pp. 515-525
-
-
Gloghini, A.1
Buglio, D.2
Khaskhely, N.M.3
Georgakis, G.4
Orlowski, R.Z.5
Neelapu, S.S.6
Carbone, A.7
Younes, A.8
-
19
-
-
34547897023
-
Histone deacetylases and cancer
-
Glozak, M.A. Seto, E. (2007) Histone deacetylases and cancer. Oncogene, 26, 5420 5432.
-
(2007)
Oncogene
, vol.26
, pp. 5420-5432
-
-
Glozak, M.A.1
Seto, E.2
-
20
-
-
0036193460
-
MEF2-mediated recruitment of class II HDAC at the EBV immediate early gene BZLF1 links latency and chromatin remodeling
-
Gruffat, H., Manet, E. Sergeant, A. (2002) MEF2-mediated recruitment of class II HDAC at the EBV immediate early gene BZLF1 links latency and chromatin remodeling. EMBO Reports, 3, 141 146.
-
(2002)
EMBO Reports
, vol.3
, pp. 141-146
-
-
Gruffat, H.1
Manet, E.2
Sergeant, A.3
-
21
-
-
3543054544
-
Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment
-
Holleman, A., Cheok, M.H., den Boer, M.L., Yang, W., Veerman, A.J., Kazemier, K.M., Pei, D., Cheng, C., Pui, C.H., Relling, M.V., Janka-Schaub, G.E., Pieters, R. Evans, W.E. (2004) Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment. New England Journal of Medicine, 351, 533 542.
-
(2004)
New England Journal of Medicine
, vol.351
, pp. 533-542
-
-
Holleman, A.1
Cheok, M.H.2
Den Boer, M.L.3
Yang, W.4
Veerman, A.J.5
Kazemier, K.M.6
Pei, D.7
Cheng, C.8
Pui, C.H.9
Relling, M.V.10
Janka-Schaub, G.E.11
Pieters, R.12
Evans, W.E.13
-
22
-
-
34548138278
-
Epigenetics: A historical overview
-
Holliday, R. (2006) Epigenetics: a historical overview. Epigenetics, 1, 76 80.
-
(2006)
Epigenetics
, vol.1
, pp. 76-80
-
-
Holliday, R.1
-
23
-
-
34547909260
-
HDAC3: Taking the SMRT-N-CoRrect road to repression
-
Karagianni, P. Wong, J. (2007) HDAC3: taking the SMRT-N-CoRrect road to repression. Oncogene, 26, 5439 5449.
-
(2007)
Oncogene
, vol.26
, pp. 5439-5449
-
-
Karagianni, P.1
Wong, J.2
-
24
-
-
4744368147
-
Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity
-
Kato, H., Tamamizu-Kato, S. Shibasaki, F. (2004) Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity. Journal of Biological Chemistry, 279, 41966 41974.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 41966-41974
-
-
Kato, H.1
Tamamizu-Kato, S.2
Shibasaki, F.3
-
25
-
-
70349469582
-
NF-kappaB family of transcription factor facilitates gene conversion in chicken B cells
-
Kim, Y. Tian, M. (2009) NF-kappaB family of transcription factor facilitates gene conversion in chicken B cells. Molecular Immunology, 46, 3283 3291.
-
(2009)
Molecular Immunology
, vol.46
, pp. 3283-3291
-
-
Kim, Y.1
Tian, M.2
-
26
-
-
0038544192
-
Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents
-
Kim, D.H., Kim, M. Kwon, H.J. (2003) Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents. Journal of Biochemistry and Molecular Biology, 36, 110 119.
-
(2003)
Journal of Biochemistry and Molecular Biology
, vol.36
, pp. 110-119
-
-
Kim, D.H.1
Kim, M.2
Kwon, H.J.3
-
27
-
-
38949144400
-
Tolerability, pharmacodynamics, and pharmacokinetics studies of depsipeptide (romidepsin) in patients with acute myelogenous leukemia or advanced myelodysplastic syndromes
-
Klimek, V.M., Fircanis, S., Maslak, P., Guernah, I., Baum, M., Wu, N., Panageas, K., Wright, J.J., Pandolfi, P.P. Nimer, S.D. (2008) Tolerability, pharmacodynamics, and pharmacokinetics studies of depsipeptide (romidepsin) in patients with acute myelogenous leukemia or advanced myelodysplastic syndromes. Clinical Cancer Research, 14, 826 832.
-
(2008)
Clinical Cancer Research
, vol.14
, pp. 826-832
-
-
Klimek, V.M.1
Fircanis, S.2
Maslak, P.3
Guernah, I.4
Baum, M.5
Wu, N.6
Panageas, K.7
Wright, J.J.8
Pandolfi, P.P.9
Nimer, S.D.10
-
28
-
-
16844385708
-
Histone deacetylase-1 and -3 protein expression in human breast cancer: A tissue microarray analysis
-
Krusche, C.A., Wulfing, P., Kersting, C., Vloet, A., Bocker, W., Kiesel, L., Beier, H.M. Alfer, J. (2005) Histone deacetylase-1 and -3 protein expression in human breast cancer: a tissue microarray analysis. Breast Cancer Research and Treatment, 90, 15 23.
-
(2005)
Breast Cancer Research and Treatment
, vol.90
, pp. 15-23
-
-
Krusche, C.A.1
Wulfing, P.2
Kersting, C.3
Vloet, A.4
Bocker, W.5
Kiesel, L.6
Beier, H.M.7
Alfer, J.8
-
29
-
-
73949128107
-
Histone deacetylase inhibitors in cancer therapy
-
Lane, A.A. Chabner, B.A. (2009) Histone deacetylase inhibitors in cancer therapy. Journal of Clinical Oncology, 27, 5459 5468.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
-
30
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak, K.J. Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods, 25, 402 408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
31
-
-
33748935350
-
Epigenetics, disease, and therapeutic interventions
-
Lu, Q., Qiu, X., Hu, N., Wen, H., Su, Y. Richardson, B.C. (2006) Epigenetics, disease, and therapeutic interventions. Ageing Research Reviews, 5, 449 467.
-
(2006)
Ageing Research Reviews
, vol.5
, pp. 449-467
-
-
Lu, Q.1
Qiu, X.2
Hu, N.3
Wen, H.4
Su, Y.5
Richardson, B.C.6
-
32
-
-
52249090461
-
Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: Class II and IV are hypoexpressed in glioblastomas
-
Lucio-Eterovic, A.K., Cortez, M.A., Valera, E.T., Motta, F.J., Queiroz, R.G., Machado, H.R., Carlotti, Jr., C.G., Neder, L., Scrideli, C.A. Tone, L.G. (2008) Differential expression of 12 histone deacetylase (HDAC) genes in astrocytomas and normal brain tissue: class II and IV are hypoexpressed in glioblastomas. BMC Cancer, 8, 243.
-
(2008)
BMC Cancer
, vol.8
, pp. 243
-
-
Lucio-Eterovic, A.K.1
Cortez, M.A.2
Valera, E.T.3
Motta, F.J.4
Queiroz, R.G.5
MacHado, H.R.6
Carlotti Jr., C.G.7
Neder, L.8
Scrideli, C.A.9
Tone, L.G.10
-
33
-
-
36148950997
-
FDA approval summary: Vorinostat for treatment of advanced primary cutaneous T-cell lymphoma
-
Mann, B.S., Johnson, J.R., Cohen, M.H., Justice, R. Pazdur, R. (2007) FDA approval summary: vorinostat for treatment of advanced primary cutaneous T-cell lymphoma. Oncologist, 12, 1247 1252.
-
(2007)
Oncologist
, vol.12
, pp. 1247-1252
-
-
Mann, B.S.1
Johnson, J.R.2
Cohen, M.H.3
Justice, R.4
Pazdur, R.5
-
34
-
-
0035755974
-
Histone deacetylases and cancer: Causes and therapies
-
Marks, P., Rifkind, R.A., Richon, V.M., Breslow, R., Miller, T. Kelly, W.K. (2001) Histone deacetylases and cancer: causes and therapies. Nature Reviews. Cancer, 1, 194 202.
-
(2001)
Nature Reviews. Cancer
, vol.1
, pp. 194-202
-
-
Marks, P.1
Rifkind, R.A.2
Richon, V.M.3
Breslow, R.4
Miller, T.5
Kelly, W.K.6
-
35
-
-
50049108874
-
Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma
-
Marquard, L., Gjerdrum, L.M., Christensen, I.J., Jensen, P.B., Sehested, M. Ralfkiaer, E. (2008) Prognostic significance of the therapeutic targets histone deacetylase 1, 2, 6 and acetylated histone H4 in cutaneous T-cell lymphoma. Histopathology, 53, 267 277.
-
(2008)
Histopathology
, vol.53
, pp. 267-277
-
-
Marquard, L.1
Gjerdrum, L.M.2
Christensen, I.J.3
Jensen, P.B.4
Sehested, M.5
Ralfkiaer, E.6
-
36
-
-
65349137584
-
Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas
-
Marquard, L., Poulsen, C.B., Gjerdrum, L.M., de Nully Brown, P., Christensen, I.J., Jensen, P.B., Sehested, M., Johansen, P. Ralfkiaer, E. (2009) Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas. Histopathology, 54, 688 698.
-
(2009)
Histopathology
, vol.54
, pp. 688-698
-
-
Marquard, L.1
Poulsen, C.B.2
Gjerdrum, L.M.3
De Nully Brown, P.4
Christensen, I.J.5
Jensen, P.B.6
Sehested, M.7
Johansen, P.8
Ralfkiaer, E.9
-
37
-
-
32044462036
-
Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes
-
Matthews, S.A., Liu, P., Spitaler, M., Olson, E.N., McKinsey, T.A., Cantrell, D.A. Scharenberg, A.M. (2006) Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes. Molecular and Cellular Biology, 26, 1569 1577.
-
(2006)
Molecular and Cellular Biology
, vol.26
, pp. 1569-1577
-
-
Matthews, S.A.1
Liu, P.2
Spitaler, M.3
Olson, E.N.4
McKinsey, T.A.5
Cantrell, D.A.6
Scharenberg, A.M.7
-
38
-
-
0036014986
-
Histone deacetylases as therapeutic targets in hematologic malignancies
-
Melnick, A. Licht, J.D. (2002) Histone deacetylases as therapeutic targets in hematologic malignancies. Current Opinion in Hematology, 9, 322 332.
-
(2002)
Current Opinion in Hematology
, vol.9
, pp. 322-332
-
-
Melnick, A.1
Licht, J.D.2
-
39
-
-
30344477367
-
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
-
Minucci, S. Pelicci, P.G. (2006) Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nature Reviews. Cancer, 6, 38 51.
-
(2006)
Nature Reviews. Cancer
, vol.6
, pp. 38-51
-
-
Minucci, S.1
Pelicci, P.G.2
-
40
-
-
38449100788
-
Expression profile of class i histone deacetylases in human cancer tissues
-
Nakagawa, M., Oda, Y., Eguchi, T., Aishima, S., Yao, T., Hosoi, F., Basaki, Y., Ono, M., Kuwano, M., Tanaka, M. Tsuneyoshi, M. (2007) Expression profile of class I histone deacetylases in human cancer tissues. Oncology Reports, 18, 769 774.
-
(2007)
Oncology Reports
, vol.18
, pp. 769-774
-
-
Nakagawa, M.1
Oda, Y.2
Eguchi, T.3
Aishima, S.4
Yao, T.5
Hosoi, F.6
Basaki, Y.7
Ono, M.8
Kuwano, M.9
Tanaka, M.10
Tsuneyoshi, M.11
-
41
-
-
34547683194
-
Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma
-
Olsen, E.A., Kim, Y.H., Kuzel, T.M., Pacheco, T.R., Foss, F.M., Parker, S., Frankel, S.R., Chen, C., Ricker, J.L., Arduino, J.M. Duvic, M. (2007) Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. Journal of Clinical Oncology, 25, 3109 3115.
-
(2007)
Journal of Clinical Oncology
, vol.25
, pp. 3109-3115
-
-
Olsen, E.A.1
Kim, Y.H.2
Kuzel, T.M.3
Pacheco, T.R.4
Foss, F.M.5
Parker, S.6
Frankel, S.R.7
Chen, C.8
Ricker, J.L.9
Arduino, J.M.10
Duvic, M.11
-
42
-
-
4544322261
-
Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients
-
Osada, H., Tatematsu, Y., Saito, H., Yatabe, Y., Mitsudomi, T. Takahashi, T. (2004) Reduced expression of class II histone deacetylase genes is associated with poor prognosis in lung cancer patients. International Journal of Cancer, 112, 26 32.
-
(2004)
International Journal of Cancer
, vol.112
, pp. 26-32
-
-
Osada, H.1
Tatematsu, Y.2
Saito, H.3
Yatabe, Y.4
Mitsudomi, T.5
Takahashi, T.6
-
43
-
-
48149115853
-
High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas
-
Ouaissi, M., Sielezneff, I., Silvestre, R., Sastre, B., Bernard, J.P., Lafontaine, J.S., Payan, M.J., Dahan, L., Pirro, N., Seitz, J.F., Mas, E., Lombardo, D. Ouaissi, A. (2008) High histone deacetylase 7 (HDAC7) expression is significantly associated with adenocarcinomas of the pancreas. Annals of Surgical Oncology, 15, 2318 2328.
-
(2008)
Annals of Surgical Oncology
, vol.15
, pp. 2318-2328
-
-
Ouaissi, M.1
Sielezneff, I.2
Silvestre, R.3
Sastre, B.4
Bernard, J.P.5
Lafontaine, J.S.6
Payan, M.J.7
Dahan, L.8
Pirro, N.9
Seitz, J.F.10
Mas, E.11
Lombardo, D.12
Ouaissi, A.13
-
44
-
-
0038521295
-
The histone deacetylase 9 gene encodes multiple protein isoforms
-
Petrie, K., Guidez, F., Howell, L., Healy, L., Waxman, S., Greaves, M. Zelent, A. (2003) The histone deacetylase 9 gene encodes multiple protein isoforms. Journal of Biological Chemistry, 278, 16059 16072.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 16059-16072
-
-
Petrie, K.1
Guidez, F.2
Howell, L.3
Healy, L.4
Waxman, S.5
Greaves, M.6
Zelent, A.7
-
45
-
-
0032475856
-
Myocyte enhancer factor-related B-MEF2 is developmentally expressed in B cells and regulates the immunoglobulin J chain promoter
-
Rao, S., Karray, S., Gackstetter, E.R. Koshland, M.E. (1998) Myocyte enhancer factor-related B-MEF2 is developmentally expressed in B cells and regulates the immunoglobulin J chain promoter. Journal of Biological Chemistry, 273, 26123 26129.
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 26123-26129
-
-
Rao, S.1
Karray, S.2
Gackstetter, E.R.3
Koshland, M.E.4
-
46
-
-
2942755609
-
Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia
-
Romanski, A., Bacic, B., Bug, G., Pfeifer, H., Gul, H., Remiszewski, S., Hoelzer, D., Atadja, P., Ruthardt, M. Ottmann, O.G. (2004) Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia. Haematologica, 89, 419 426.
-
(2004)
Haematologica
, vol.89
, pp. 419-426
-
-
Romanski, A.1
Bacic, B.2
Bug, G.3
Pfeifer, H.4
Gul, H.5
Remiszewski, S.6
Hoelzer, D.7
Atadja, P.8
Ruthardt, M.9
Ottmann, O.G.10
-
47
-
-
34248631385
-
The role of histone deacetylases (HDACs) in human cancer
-
Ropero, S. Esteller, M. (2007) The role of histone deacetylases (HDACs) in human cancer. Molecular Oncology, 1, 19 25.
-
(2007)
Molecular Oncology
, vol.1
, pp. 19-25
-
-
Ropero, S.1
Esteller, M.2
-
48
-
-
0141993002
-
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling
-
Ross, M.E., Zhou, X., Song, G., Shurtleff, S.A., Girtman, K., Williams, W.K., Liu, H.C., Mahfouz, R., Raimondi, S.C., Lenny, N., Patel, A. Downing, J.R. (2003) Classification of pediatric acute lymphoblastic leukemia by gene expression profiling. Blood, 102, 2951 2959.
-
(2003)
Blood
, vol.102
, pp. 2951-2959
-
-
Ross, M.E.1
Zhou, X.2
Song, G.3
Shurtleff, S.A.4
Girtman, K.5
Williams, W.K.6
Liu, H.C.7
Mahfouz, R.8
Raimondi, S.C.9
Lenny, N.10
Patel, A.11
Downing, J.R.12
-
49
-
-
12344330351
-
Histone deacetylase inhibitors profoundly decrease proliferation of human lymphoid cancer cell lines
-
Sakajiri, S., Kumagai, T., Kawamata, N., Saitoh, T., Said, J.W. Koeffler, H.P. (2005) Histone deacetylase inhibitors profoundly decrease proliferation of human lymphoid cancer cell lines. Experimental Hematology, 33, 53 61.
-
(2005)
Experimental Hematology
, vol.33
, pp. 53-61
-
-
Sakajiri, S.1
Kumagai, T.2
Kawamata, N.3
Saitoh, T.4
Said, J.W.5
Koeffler, H.P.6
-
50
-
-
56949091946
-
Sodium butyrate enhances the cytotoxic effect of antineoplastic drugs in human lymphoblastic T-cells
-
dos Santos, M.P., Schwartsmann, G., Roesler, R., Brunetto, A.L. Abujamra, A.L. (2009) Sodium butyrate enhances the cytotoxic effect of antineoplastic drugs in human lymphoblastic T-cells. Leukemia Research, 33, 218 221.
-
(2009)
Leukemia Research
, vol.33
, pp. 218-221
-
-
Dos Santos, M.P.1
Schwartsmann, G.2
Roesler, R.3
Brunetto, A.L.4
Abujamra, A.L.5
-
51
-
-
38949204406
-
Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera
-
Sasaki, K., Yamagata, T. Mitani, K. (2008) Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera. Cancer Science, 99, 414 422.
-
(2008)
Cancer Science
, vol.99
, pp. 414-422
-
-
Sasaki, K.1
Yamagata, T.2
Mitani, K.3
-
52
-
-
0032212271
-
Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer
-
Satyaraj, E. Storb, U. (1998) Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer. Journal of Immunology, 161, 4795 4802.
-
(1998)
Journal of Immunology
, vol.161
, pp. 4795-4802
-
-
Satyaraj, E.1
Storb, U.2
-
53
-
-
66749132483
-
A simplified minimal residual disease polymerase chain reaction method at early treatment points can stratify children with acute lymphoblastic leukemia into good and poor outcome groups
-
Scrideli, C.A., Assumpcao, J.G., Ganazza, M.A., Araujo, M., Toledo, S.R., Lee, M.L., Delbuono, E., Petrilli, A.S., Queiroz, R.P., Biondi, A., Viana, M.B., Yunes, J.A., Brandalise, S.R. Tone, L.G. (2009) A simplified minimal residual disease polymerase chain reaction method at early treatment points can stratify children with acute lymphoblastic leukemia into good and poor outcome groups. Haematologica, 94, 781 789.
-
(2009)
Haematologica
, vol.94
, pp. 781-789
-
-
Scrideli, C.A.1
Assumpcao, J.G.2
Ganazza, M.A.3
Araujo, M.4
Toledo, S.R.5
Lee, M.L.6
Delbuono, E.7
Petrilli, A.S.8
Queiroz, R.P.9
Biondi, A.10
Viana, M.B.11
Yunes, J.A.12
Brandalise, S.R.13
Tone, L.G.14
-
54
-
-
0345647074
-
Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes
-
Swanson, B.J., Jack, H.M. Lyons, G.E. (1998) Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes. Molecular Immunology, 35, 445 458.
-
(1998)
Molecular Immunology
, vol.35
, pp. 445-458
-
-
Swanson, B.J.1
Jack, H.M.2
Lyons, G.E.3
-
55
-
-
34447096461
-
HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway
-
Tsapis, M., Lieb, M., Manzo, F., Shankaranarayanan, P., Herbrecht, R., Lutz, P. Gronemeyer, H. (2007) HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway. International Journal of Biochemistry and Cell Biology, 39, 1500 1509.
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, pp. 1500-1509
-
-
Tsapis, M.1
Lieb, M.2
Manzo, F.3
Shankaranarayanan, P.4
Herbrecht, R.5
Lutz, P.6
Gronemeyer, H.7
-
56
-
-
0037406061
-
Class II histone deacetylases: Versatile regulators
-
Verdin, E., Dequiedt, F. Kasler, H.G. (2003) Class II histone deacetylases: versatile regulators. Trends in Genetics, 19, 286 293.
-
(2003)
Trends in Genetics
, vol.19
, pp. 286-293
-
-
Verdin, E.1
Dequiedt, F.2
Kasler, H.G.3
-
57
-
-
73449117582
-
Immunomodulatory effects of deacetylase inhibitors: Therapeutic targeting of FOXP3+ regulatory T cells
-
Wang, L., de Zoeten, E.F., Greene, M.I. Hancock, W.W. (2009) Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells. Nature Reviews. Drug Discovery, 8, 969 981.
-
(2009)
Nature Reviews. Drug Discovery
, vol.8
, pp. 969-981
-
-
Wang, L.1
De Zoeten, E.F.2
Greene, M.I.3
Hancock, W.W.4
-
58
-
-
67349160499
-
HDAC expression and clinical prognosis in human malignancies
-
Weichert, W. (2009) HDAC expression and clinical prognosis in human malignancies. Cancer Letters, 280, 168 176.
-
(2009)
Cancer Letters
, vol.280
, pp. 168-176
-
-
Weichert, W.1
-
59
-
-
50949104573
-
Expression of class i histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas
-
Weichert, W., Denkert, C., Noske, A., Darb-Esfahani, S., Dietel, M., Kalloger, S.E., Huntsman, D.G. Kobel, M. (2008a) Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas. Neoplasia, 10, 1021 1027.
-
(2008)
Neoplasia
, vol.10
, pp. 1021-1027
-
-
Weichert, W.1
Denkert, C.2
Noske, A.3
Darb-Esfahani, S.4
Dietel, M.5
Kalloger, S.E.6
Huntsman, D.G.7
Kobel, M.8
-
60
-
-
38549157208
-
Association of patterns of class i histone deacetylase expression with patient prognosis in gastric cancer: A retrospective analysis
-
Weichert, W., Roske, A., Gekeler, V., Beckers, T., Ebert, M.P., Pross, M., Dietel, M., Denkert, C. Rocken, C. (2008b) Association of patterns of class I histone deacetylase expression with patient prognosis in gastric cancer: a retrospective analysis. The Lancet Oncology, 9, 139 148.
-
(2008)
The Lancet Oncology
, vol.9
, pp. 139-148
-
-
Weichert, W.1
Roske, A.2
Gekeler, V.3
Beckers, T.4
Ebert, M.P.5
Pross, M.6
Dietel, M.7
Denkert, C.8
Rocken, C.9
-
61
-
-
38949086502
-
Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy
-
Weichert, W., Roske, A., Gekeler, V., Beckers, T., Stephan, C., Jung, K., Fritzsche, F.R., Niesporek, S., Denkert, C., Dietel, M. Kristiansen, G. (2008c) Histone deacetylases 1, 2 and 3 are highly expressed in prostate cancer and HDAC2 expression is associated with shorter PSA relapse time after radical prostatectomy. British Journal of Cancer, 98, 604 610.
-
(2008)
British Journal of Cancer
, vol.98
, pp. 604-610
-
-
Weichert, W.1
Roske, A.2
Gekeler, V.3
Beckers, T.4
Stephan, C.5
Jung, K.6
Fritzsche, F.R.7
Niesporek, S.8
Denkert, C.9
Dietel, M.10
Kristiansen, G.11
-
62
-
-
41549159879
-
Class i histone deacetylase expression has independent prognostic impact in human colorectal cancer: Specific role of class i histone deacetylases in vitro and in vivo
-
Weichert, W., Roske, A., Niesporek, S., Noske, A., Buckendahl, A.C., Dietel, M., Gekeler, V., Boehm, M., Beckers, T. Denkert, C. (2008d) Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo. Clinical Cancer Research, 14, 1669 1677.
-
(2008)
Clinical Cancer Research
, vol.14
, pp. 1669-1677
-
-
Weichert, W.1
Roske, A.2
Niesporek, S.3
Noske, A.4
Buckendahl, A.C.5
Dietel, M.6
Gekeler, V.7
Boehm, M.8
Beckers, T.9
Denkert, C.10
-
63
-
-
61849144810
-
HDAC family: What are the cancer relevant targets?
-
Witt, O., Deubzer, H.E., Milde, T. Oehme, I. (2009) HDAC family: what are the cancer relevant targets? Cancer Letters, 277, 8 21.
-
(2009)
Cancer Letters
, vol.277
, pp. 8-21
-
-
Witt, O.1
Deubzer, H.E.2
Milde, T.3
Oehme, I.4
-
64
-
-
70349876894
-
Mechanism-anchored profiling derived from epigenetic networks predicts outcome in acute lymphoblastic leukemia
-
Yang, X., Huang, Y., Chen, J.L., Xie, J., Sun, X. Lussier, Y.A. (2009) Mechanism-anchored profiling derived from epigenetic networks predicts outcome in acute lymphoblastic leukemia. BMC Bioinformatics, 10 (Suppl. 9 S6.
-
(2009)
BMC Bioinformatics
, vol.10
, Issue.SUPPL. 9
, pp. 6
-
-
Yang, X.1
Huang, Y.2
Chen, J.L.3
Xie, J.4
Sun, X.5
Lussier, Y.A.6
-
65
-
-
0033681541
-
Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2
-
Youn, H.D. Liu, J.O. (2000) Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2. Immunity, 13, 85 94.
-
(2000)
Immunity
, vol.13
, pp. 85-94
-
-
Youn, H.D.1
Liu, J.O.2
-
66
-
-
0033595816
-
Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2
-
Youn, H.D., Sun, L., Prywes, R. Liu, J.O. (1999) Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2. Science, 286, 790 793.
-
(1999)
Science
, vol.286
, pp. 790-793
-
-
Youn, H.D.1
Sun, L.2
Prywes, R.3
Liu, J.O.4
-
67
-
-
0034663805
-
Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis
-
Youn, H.D., Chatila, T.A. Liu, J.O. (2000) Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis. EMBO Journal, 19, 4323 4331.
-
(2000)
EMBO Journal
, vol.19
, pp. 4323-4331
-
-
Youn, H.D.1
Chatila, T.A.2
Liu, J.O.3
-
68
-
-
0035845539
-
Cloning and characterization of a histone deacetylase, HDAC9
-
Zhou, X., Marks, P.A., Rifkind, R.A. Richon, V.M. (2001) Cloning and characterization of a histone deacetylase, HDAC9. Proceedings of the National Academy of Sciences of the United States of America, 98, 10572 10577.
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, pp. 10572-10577
-
-
Zhou, X.1
Marks, P.A.2
Rifkind, R.A.3
Richon, V.M.4
|