-
1
-
-
0032524104
-
Landscaping the cancer terrain
-
Kinzler K.W., Vogelstein B. Landscaping the cancer terrain. Science. 280:1998;1036-1037.
-
(1998)
Science
, vol.280
, pp. 1036-1037
-
-
Kinzler, K.W.1
Vogelstein, B.2
-
2
-
-
0033119780
-
DNA methylation and chromatin modification
-
Ng H.-H., Bird A. DNA methylation and chromatin modification. Curr. Opin. Genet. Dev. 9:1999;158-163.
-
(1999)
Curr. Opin. Genet. Dev.
, vol.9
, pp. 158-163
-
-
Ng, H.-H.1
Bird, A.2
-
3
-
-
0030115772
-
Creation of genomic methylation patterns
-
Bestor T.H., Tycko B. Creation of genomic methylation patterns. Nat. Genet. 12:1996;363-367.
-
(1996)
Nat. Genet.
, vol.12
, pp. 363-367
-
-
Bestor, T.H.1
Tycko, B.2
-
4
-
-
0032076565
-
Imprinting and the initiation of gene silencing in the germ line
-
Surani M.A. Imprinting and the initiation of gene silencing in the germ line. Cell. 93:1998;309-312.
-
(1998)
Cell
, vol.93
, pp. 309-312
-
-
Surani, M.A.1
-
5
-
-
0030846212
-
Alterations in DNA methylation: A fundamental aspect of neoplasia
-
G. Klein, & G.F. Van de Woude. Academic Press
-
Baylin S.B. Alterations in DNA methylation: A fundamental aspect of neoplasia. Klein G., Van de Woude G.F. Advances in Cancer Research. 1998;141-196 Academic Press.
-
(1998)
Advances in Cancer Research
, pp. 141-196
-
-
Baylin, S.B.1
-
6
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones P.A., Laird P.W. Cancer epigenetics comes of age. Nat. Genet. 21:1999;163-167.
-
(1999)
Nat. Genet.
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
7
-
-
0028072991
-
Silencing of the VHL tumor suppressor gene by DNA methylation in renal carcinoma
-
Herman J.G.et al. Silencing of the VHL tumor suppressor gene by DNA methylation in renal carcinoma. Proc. Natl. Acad. Sci. U. S. A. 91:1994;9700-9704.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
-
8
-
-
0029849620
-
Cancer cell cycles
-
Sherr C.J. Cancer cell cycles. Science. 274:1996;1672-1677.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
9
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Kamb A.et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science. 264:1994;436-440.
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
-
10
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman J.G.et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res. 55:1995;4525-4530.
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
-
11
-
-
0027158031
-
Clues to the pathogenesis of familial colorectal cancer
-
Aaltonen L.A.et al. Clues to the pathogenesis of familial colorectal cancer. Science. 260:1993;812-816.
-
(1993)
Science
, vol.260
, pp. 812-816
-
-
Aaltonen, L.A.1
-
12
-
-
10344228783
-
Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes
-
Thibodeau S.N.et al. Altered expression of hMSH2 and hMLH1 in tumors with microsatellite instability and genetic alterations in mismatch repair genes. Cancer Res. 56:1996;4836-4840.
-
(1996)
Cancer Res.
, vol.56
, pp. 4836-4840
-
-
Thibodeau, S.N.1
-
13
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
Herman J.G.et al. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc. Natl. Acad. Sci. U. S. A. 95:1998;6870-6875.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
-
14
-
-
0030007144
-
Mutations of the BRCA1 gene in human cancer
-
Xu C.F., Solomon E. Mutations of the BRCA1 gene in human cancer. Semin. Cancer Biol. 7:1996;33-40.
-
(1996)
Semin. Cancer Biol.
, vol.7
, pp. 33-40
-
-
Xu, C.F.1
Solomon, E.2
-
15
-
-
0034607234
-
Promoter hypermethylation is a cause of BRCA1 inactivation in sporadic breast and ovarian tumors
-
Esteller M.et al. Promoter hypermethylation is a cause of BRCA1 inactivation in sporadic breast and ovarian tumors. J. Natl. Cancer Inst. 2000;(in press).
-
(2000)
J. Natl. Cancer Inst.
-
-
Esteller, M.1
-
16
-
-
0029114538
-
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas
-
Yoshiura K.et al. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc. Natl. Acad. Sci. U. S. A. 92:1995;7416-7419.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 7416-7419
-
-
Yoshiura, K.1
-
17
-
-
0028849277
-
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas
-
Graff J.R.et al. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res. 55:1995;5195-5199.
-
(1995)
Cancer Res.
, vol.55
, pp. 5195-5199
-
-
Graff, J.R.1
-
18
-
-
15144350589
-
Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carinoma
-
Graff J.R.et al. Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carinoma. Cancer Res. 58:1998;2063-2066.
-
(1998)
Cancer Res.
, vol.58
, pp. 2063-2066
-
-
Graff, J.R.1
-
19
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
Kane M.F.et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res. 57:1997;808-811.
-
(1997)
Cancer Res.
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
-
20
-
-
0032487831
-
MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas
-
Esteller M.et al. MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas. Oncogene. 17:1998;2413-2417.
-
(1998)
Oncogene
, vol.17
, pp. 2413-2417
-
-
Esteller, M.1
-
21
-
-
0001119305
-
HMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability
-
Leung S.Y.et al. hMLH1 promoter methylation and lack of hMLH1 expression in sporadic gastric carcinomas with high-frequency microsatellite instability. Cancer Res. 59:1999;159-164.
-
(1999)
Cancer Res.
, vol.59
, pp. 159-164
-
-
Leung, S.Y.1
-
22
-
-
0034610730
-
Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome
-
Esteller M.et al. Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome. Oncogene. 19:2000;164-168.
-
(2000)
Oncogene
, vol.19
, pp. 164-168
-
-
Esteller, M.1
-
23
-
-
0030046322
-
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15(INK4B)
-
Herman J.G.et al. Hypermethylation-associated inactivation indicates a tumor suppressor role for p15(INK4B). Cancer Res. 56:1996;722-727.
-
(1996)
Cancer Res.
, vol.56
, pp. 722-727
-
-
Herman, J.G.1
-
24
-
-
0033565514
-
Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5′ CpG island methylation
-
Corn P.G.et al. Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5′ CpG island methylation. Cancer Res. 59:1999;3352-3356.
-
(1999)
Cancer Res.
, vol.59
, pp. 3352-3356
-
-
Corn, P.G.1
-
25
-
-
0033179665
-
Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation
-
Kawano S.et al. Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation. BLOOD. 94:1999;1113-1120.
-
(1999)
BLOOD
, vol.94
, pp. 1113-1120
-
-
Kawano, S.1
-
26
-
-
0031035406
-
Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia
-
Batova A.et al. Frequent and selective methylation of p15 and deletion of both p15 and p16 in T-cell acute lymphoblastic leukemia. Cancer Res. 57:1997;832-836.
-
(1997)
Cancer Res.
, vol.57
, pp. 832-836
-
-
Batova, A.1
-
27
-
-
0028318783
-
Methylation of the estrogen receptor gene CpG island marks loss of estrogen expression in human breast cancer cells
-
Ottaviano Y.L.et al. Methylation of the estrogen receptor gene CpG island marks loss of estrogen expression in human breast cancer cells. Cancer Res. 54:1994;2552-2555.
-
(1994)
Cancer Res.
, vol.54
, pp. 2552-2555
-
-
Ottaviano, Y.L.1
-
28
-
-
0028001087
-
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
-
Issa J.P.et al. Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat. Genet. 7:1994;536-540.
-
(1994)
Nat. Genet.
, vol.7
, pp. 536-540
-
-
Issa, J.P.1
-
29
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M.et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res. 59:1999;793-797.
-
(1999)
Cancer Res.
, vol.59
, pp. 793-797
-
-
Esteller, M.1
-
30
-
-
0028152397
-
Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis
-
Lee W.H.et al. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proc. Natl. Acad. Sci. U. S. A. 91:1994;11733-11737.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 11733-11737
-
-
Lee, W.H.1
-
31
-
-
0032532092
-
Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia
-
Esteller M.et al. Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia. Cancer Res. 58:1998;4515-4518.
-
(1998)
Cancer Res.
, vol.58
, pp. 4515-4518
-
-
Esteller, M.1
-
32
-
-
0033558192
-
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggests a suppressor role in kidney, brain and other human cancers
-
Bachman K.E.et al. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggests a suppressor role in kidney, brain and other human cancers. Cancer Res. 59:1999;798-802.
-
(1999)
Cancer Res.
, vol.59
, pp. 798-802
-
-
Bachman, K.E.1
-
33
-
-
0033564351
-
Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies
-
Katzenellenbogen R.et al. Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies. BLOOD. 93:1999;4347-4353.
-
(1999)
BLOOD
, vol.93
, pp. 4347-4353
-
-
Katzenellenbogen, R.1
-
34
-
-
0032578509
-
INK4a is an early event in lung cancer and a potential biomarker for early diagnosis
-
INK4a is an early event in lung cancer and a potential biomarker for early diagnosis. Proc. Natl. Acad. Sci. U. S. A. 95:1998;11891-11896.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 11891-11896
-
-
Belinsky, S.A.1
-
35
-
-
0032770313
-
Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from Mo growth arrest
-
Wong D.J.et al. Progressive region-specific de novo methylation of the p16 CpG island in primary human mammary epithelial cell strains during escape from Mo growth arrest. Mol. Cell Biol. 19:1999;5642-5651.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 5642-5651
-
-
Wong, D.J.1
-
36
-
-
0033607147
-
In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
-
Nuovo G.J.et al. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. Proc. Natl. Acad. Sci. U. S. A. 96:1999;12754-12759.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12754-12759
-
-
Nuovo, G.J.1
-
37
-
-
0013642414
-
Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithlial cells
-
Kiyono T.et al. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithlial cells. Nature. 396:1998;6706.
-
(1998)
Nature
, vol.396
, pp. 6706
-
-
Kiyono, T.1
-
38
-
-
0032706744
-
HMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis
-
Esteller M.et al. hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis. Am. J. Pathol. 155:1999;1767-1772.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1767-1772
-
-
Esteller, M.1
-
39
-
-
0343953594
-
Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia
-
Myohanen S.K.et al. Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia. Cancer Res. 58:1998;591-593.
-
(1998)
Cancer Res.
, vol.58
, pp. 591-593
-
-
Myohanen, S.K.1
-
40
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones P.L.et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet. 19:1998;187-191.
-
(1998)
Nat. Genet.
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
-
41
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan X.et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature. 393:1998;386.
-
(1998)
Nature
, vol.393
, pp. 386
-
-
Nan, X.1
-
42
-
-
0032845039
-
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
-
Wade P.A.et al. Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation. Nat. Genet. 23:1999;62-66.
-
(1999)
Nat. Genet.
, vol.23
, pp. 62-66
-
-
Wade, P.A.1
-
43
-
-
0032871399
-
MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
-
Ng H.-H.et al. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex. Nat. Genet. 23:1999;58-61.
-
(1999)
Nat. Genet.
, vol.23
, pp. 58-61
-
-
Ng, H.-H.1
-
44
-
-
0032948005
-
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer
-
Cameron E.E.et al. Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat. Genet. 21:1999;103-107.
-
(1999)
Nat. Genet.
, vol.21
, pp. 103-107
-
-
Cameron, E.E.1
-
45
-
-
0033597438
-
Transcriptional coregulators in development
-
Mannervik M.et al. Transcriptional coregulators in development. Science. 284:1999;606-609.
-
(1999)
Science
, vol.284
, pp. 606-609
-
-
Mannervik, M.1
-
46
-
-
0032030770
-
Histone acetylation and transcriptional regulatory mechanisms
-
Struhl K. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev. 12:1998;599-606.
-
(1998)
Genes Dev.
, vol.12
, pp. 599-606
-
-
Struhl, K.1
-
47
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota M.et al. CpG island methylator phenotype in colorectal cancer. Proc. Natl. Acad. Sci. U. S. A. 96:1999;8681-8686.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 8681-8686
-
-
Toyota, M.1
-
48
-
-
0033179375
-
Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia
-
Melki J.R.et al. Concurrent DNA hypermethylation of multiple genes in acute myeloid leukemia. Cancer Res. 59:1999;3730-3740.
-
(1999)
Cancer Res.
, vol.59
, pp. 3730-3740
-
-
Melki, J.R.1
-
49
-
-
0033985151
-
INK4A methylation and p53 mutational status
-
INK4A methylation and p53 mutational status. Cancer Res. 60:1999;129-133.
-
(1999)
Cancer Res.
, vol.60
, pp. 129-133
-
-
Esteller, M.1
-
50
-
-
0032894125
-
Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients
-
Esteller M.et al. Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients. Cancer Res. 59:1999;67-70.
-
(1999)
Cancer Res.
, vol.59
, pp. 67-70
-
-
Esteller, M.1
-
51
-
-
0028786951
-
Loss of methylation activates Xist in somatic but not in embryonic cells
-
Beard C.et al. Loss of methylation activates Xist in somatic but not in embryonic cells. Genes Dev. 9:1995;2325-2334.
-
(1995)
Genes Dev.
, vol.9
, pp. 2325-2334
-
-
Beard, C.1
-
52
-
-
0002799197
-
Role of DNA methylation in development in genomic imprinting
-
W. Reik, & A. Surani. IRL Press
-
Li E. Role of DNA methylation in development in genomic imprinting. Reik W., Surani A. Frontiers in Molecular Biology. 1997;1-20 IRL Press.
-
(1997)
Frontiers in Molecular Biology
, pp. 1-20
-
-
Li, E.1
-
53
-
-
0031860739
-
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
-
Okano M.et al. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat. Genet. 19:1998;219-220.
-
(1998)
Nat. Genet.
, vol.19
, pp. 219-220
-
-
Okano, M.1
-
54
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M.et al. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell. 99:1999;247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
-
55
-
-
0030983076
-
DNA methylation and genetic instability in colorectal cancer cells
-
Lengauer C.et al. DNA methylation and genetic instability in colorectal cancer cells. Proc. Natl. Acad. Sci. U. S. A. 94:1997;2545-2550.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 2545-2550
-
-
Lengauer, C.1
-
56
-
-
0033153303
-
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
-
Robertson K.D.et al. The human DNA methyltransferases (DNMTs) 1, 3a and 3b. coordinate mRNA expression in normal tissues and overexpression in tumors Nucleic Acids Res. 27:1999;2291-2298.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 2291-2298
-
-
Robertson, K.D.1
-
57
-
-
0027504621
-
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells
-
Wu J.et al. Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells. Proc. Natl. Acad. Sci. U. S. A. 90:1993;8891-8895.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 8891-8895
-
-
Wu, J.1
-
58
-
-
0033555953
-
Role of DNA 5-methylcytosine transferase in cell transformation by fos
-
Bakin A.V., Curran T. Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science. 283:1999;387-390.
-
(1999)
Science
, vol.283
, pp. 387-390
-
-
Bakin, A.V.1
Curran, T.2
-
59
-
-
0029001154
-
Suppression of intestinal neoplasia by DNA hypomethylation
-
Laird P.W.et al. Suppression of intestinal neoplasia by DNA hypomethylation. Cell. 81:1995;197-205.
-
(1995)
Cell
, vol.81
, pp. 197-205
-
-
Laird, P.W.1
-
60
-
-
0028964323
-
Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis
-
MacLeod A.R., Szyf M. Expression of antisense to DNA methyltransferase mRNA induces DNA demethylation and inhibits tumorigenesis. J. Biol. Chem. 270:1995;8037-8043.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8037-8043
-
-
MacLeod, A.R.1
Szyf, M.2
-
61
-
-
0029973718
-
De Novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase
-
Vertino P.M.et al. De Novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase. Mol. Cell Biol. 16:1996;4555-4565.
-
(1996)
Mol. Cell Biol.
, vol.16
, pp. 4555-4565
-
-
Vertino, P.M.1
-
62
-
-
0034720284
-
CpG methylation is maintained in cancer cells lacking DNMT
-
Rhee I.et al. CpG methylation is maintained in cancer cells lacking DNMT. Nature. 2000;(in press).
-
(2000)
Nature
-
-
Rhee, I.1
-
63
-
-
0031830718
-
An alternative promoter in the mouse major histocompatibility complex class II I-Abeta gene: Implications for the origin of CpG islands
-
Macleod D.et al. An alternative promoter in the mouse major histocompatibility complex class II I-Abeta gene. implications for the origin of CpG islands Mol. Cell Biol. 18:1998;4433-4443.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 4433-4443
-
-
Macleod, D.1
-
64
-
-
0028104109
-
Sp1 elements protect a CpG island from de novo methylation
-
Brandeis M.et al. Sp1 elements protect a CpG island from de novo methylation. Nature. 29:1994;435-538.
-
(1994)
Nature
, vol.29
, pp. 435-538
-
-
Brandeis, M.1
-
65
-
-
0027960055
-
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
-
Macleod D.et al. Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev. 8:1994;2282-2292.
-
(1994)
Genes Dev.
, vol.8
, pp. 2282-2292
-
-
Macleod, D.1
-
66
-
-
0030853287
-
Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation
-
Marin M.et al. Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation. Cell. 4:1997;619-628.
-
(1997)
Cell
, vol.4
, pp. 619-628
-
-
Marin, M.1
-
67
-
-
0032992224
-
DNA methylation represses transcription in vivo
-
Siegfried Z.et al. DNA methylation represses transcription in vivo. Nat. Genet. 22:1999;203-206.
-
(1999)
Nat. Genet.
, vol.22
, pp. 203-206
-
-
Siegfried, Z.1
-
68
-
-
0032171040
-
Chromatin remodeling: A marriage between two families?
-
Pollard K.J., Peterson C.L. Chromatin remodeling: a marriage between two families? BioEssays. 20:1998;771-780.
-
(1998)
BioEssays
, vol.20
, pp. 771-780
-
-
Pollard, K.J.1
Peterson, C.L.2
-
69
-
-
0032907728
-
Maintenance of genomic methylation requires a SWI2/SNF2-like protein
-
Jeddeloh J.A.et al. Maintenance of genomic methylation requires a SWI2/SNF2-like protein. Nat. Genet. 22:1999;94-97.
-
(1999)
Nat. Genet.
, vol.22
, pp. 94-97
-
-
Jeddeloh, J.A.1
-
70
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman J.G.et al. Methylation-specific PCR. A novel PCR assay for methylation status of CpG islands Proc. Natl. Acad. Sci. U. S. A. 93:1996;9821-9826.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
-
71
-
-
0030462823
-
Rapid analysis of DNA methylation using new restriction enzyme sites created by bisulfite modification
-
Sadri R., Hornsby P.J. Rapid analysis of DNA methylation using new restriction enzyme sites created by bisulfite modification. Nucleic Acids Res. 24:1996;5058-5059.
-
(1996)
Nucleic Acids Res.
, vol.24
, pp. 5058-5059
-
-
Sadri, R.1
Hornsby, P.J.2
-
72
-
-
0032893755
-
Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients
-
Wong I.H.N.et al. Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients. Cancer Res. 59:1999;71-73.
-
(1999)
Cancer Res.
, vol.59
, pp. 71-73
-
-
Wong, I.H.N.1
-
73
-
-
0031045307
-
Pharmacological approach for optimization of the dose schedule of 5-Aza-2′-deoxycytidine (Decitabine) for the therapy of leukemia
-
Momparler R.L.et al. Pharmacological approach for optimization of the dose schedule of 5-Aza-2′-deoxycytidine (Decitabine) for the therapy of leukemia. Leukemia. 11:1997;S1-S6.
-
(1997)
Leukemia
, vol.11
-
-
Momparler, R.L.1
-
74
-
-
0028151343
-
Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation
-
Juttermann R.et al. Toxicity of 5-aza-2′-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc. Natl. Acad. Sci. U. S. A. 91:1994;11797-11801.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 11797-11801
-
-
Juttermann, R.1
-
75
-
-
0031434813
-
Role of estrogen receptor gene demethylation and DNA methyltransferase DNA adduct formation in 5-Aza-2′-deoxycytidine-induced cytotoxicity in human breast cancer cells
-
Ferguson A.T.et al. Role of estrogen receptor gene demethylation and DNA methyltransferase DNA adduct formation in 5-Aza-2′-deoxycytidine-induced cytotoxicity in human breast cancer cells. J. Biol. Chem. 272:1997;32260-32266.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32260-32266
-
-
Ferguson, A.T.1
|