The mRNA expression of SETD2 in human breast cancer: Correlation with clinico-pathological parameters

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Al Sarakbi, W ^a   Sasi, W ^a   Jiang, W G ^b   Roberts, Terry ^c   Newbold, Robert F ^c   Mokbel, Kefah ^a,c  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

^c BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE METHYLTRANSFERASE; MESSENGER RNA; SET DOMAIN CONTAINING PROTEIN 2; UNCLASSIFIED DRUG; HISTONE LYSINE METHYLTRANSFERASE; SET2 PROTEIN, HUMAN;

ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER INHIBITION; CANCER LOCALIZATION; CANCER MORTALITY; CANCER RECURRENCE; CANCER STAGING; CONTROLLED STUDY; GENE EXPRESSION; GENE FUNCTION; GENETIC ASSOCIATION; HUMAN; HUMAN TISSUE; METASTASIS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; BREAST TUMOR; FEMALE; FOLLOW UP; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY;

BREAST NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; NEOPLASM STAGING; RNA, MESSENGER;

EID: 70049111751     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-290     Document Type: Article

References (17)

1. Sun XJ Wei J Wu XY Hu M Wang L Wang HH et al Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase J Biol Chem 2005, 280(42):35261-71 10.1074/ jbc.M504012200 16118227
2. Cuthbert AP Bond J Trott DA Gill S Broni J Marriott A et al Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells J Natl Cancer Inst 1999, 91(1):37-45 10.1093/jnci/91.1.37 9890168
3. Li M Phatnani HP Guan Z Sage H Greenleaf AL Zhou P Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1 Proc Natl Acad Sci USA 2005, 102(49):17636-41 10.1073/pnas.0506350102 1308900 16314571
4. Rega S Stiewe T Chang DI Pollmeier B Esche H Bardenheuer W et al Identification of the full-length huntingtin- interacting protein p231HBP/HYPB as a DNA-binding factor Mol Cell Neurosci 2001, 18(1):68-79 10.1006/mcne.2001.1004 11461154
5. Passani LA Bedford MT Faber PW McGinnis KM Sharp AH Gusella JF et al Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis Hum Mol Genet 2000, 9(14):2175-82 10.1093/hmg/ 9.14.2175 10958656
6. Faber PW Barnes GT Srinidhi J Chen J Gusella JF MacDonald ME Huntingtin interacts with a family of WW domain proteins Hum Mol Genet 1998, 7(9):1463-74 10.1093/hmg/7.9.1463 9700202
7. Edmunds JW Mahadevan LC Clayton AL Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation EMBO J 2008, 27(2):406-20 10.1038/sj.emboj.7601967 2168397,2168397 18157086
8. Xie P Tian C An L Nie J Lu K Xing G et al Histone methyltransferase protein SETD2 interacts with p53 and selectively regulates its downstream genes Cell Signal 2008, 20(9):1671-8 10.1016/ j.cellsig.2008.05.012 18585004
9. Jiang WG Douglas-Jones A Mansel RE Level of expression of PPAR-gamma and its co-activator (PPAR-GCA) in human breast cancer Int J Cancer 2003, 106:752-757 10.1002/ijc.11302 12866036
10. Jiang WG Watkins G Lane J et al Prognostic value of Rho familty and and rho-GDIs in breast cancer Clin Cancer Res 2003, 9:6432-6440 14695145
11. Jiang WG Watkins G Fodstad O Douglas-Jones A Mokbel K Mansel RE Differential expression of the CCN family members Cyr61 from CTGF and Nov in human breast cancer Endocrine Related Cancers 2004, 11:781-791 10.1677/erc.1.00825
12. Spencer VA Davie JR Role of covalent modifications of histones in regulating gene expression Gene 1999, 240(1):1-12 10.1016/ S0378-1119(99)00405-9 10564807
13. Strahl BD Allis CD The language of covalent histone modifications Nature 2000, 403(6765):41-5 10.1038/47412 10638745
14. Turner BM Histone acetylation and an epigenetic code Bioessays 2000, 22(9):836-45 10.1002/ 1521-1878(200009)22:9<836::AID-BIES9>3.0.CO;2-X 10944586
15. Wolffe AP Transcriptional regulation in the context of chromatin structure Essays Biochem 2001, 37:45-57 11758456
16. Prives C Hall PA The p53 pathway J Pathol 1999, 187(1):112-26 10.1002/ (SICI)1096-9896(199901)187:1<112::AID-PATH250>3.0.CO;2-3 10341712
17. Goodsell DS The molecular perspective: P53 tumor suppressor Oncologist 1999, 4(2):138-9 10337384