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Volumn 481, Issue 7380, 2012, Pages 157-163

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(69)  Zhang, Jinghui a   Ding, Li b   Holmfeldt, Linda a   Wu, Gang a   Heatley, Sue L a,n   Payne Turner, Debbie a   Easton, John a   Chen, Xiang a   Wang, Jianmin a   Rusch, Michael a   Lu, Charles b   Chen, Shann Ching a   Wei, Lei a   Collins Underwood, J Racquel a   Ma, Jing a   Roberts, Kathryn G a   Pounds, Stanley B a   Ulyanov, Anatoly a   Becksfort, Jared a   Gupta, Pankaj a   more..


Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; CD135 ANTIGEN; CYTOKINE RECEPTOR; DNM2 PROTEIN; E1A ASSOCIATED P300 PROTEIN; ECT2L PROTEIN; EMBRYONIC ECTODERM DEVELOPMENT PROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN R; INTERLEUKIN 7 RECEPTOR; JANUS KINASE 1; JANUS KINASE 3; K RAS PROTEIN; NRAS PROTEIN; PHF6 PROTEIN; RAS PROTEIN; REELIN; SETD2 PROTEIN; SH2B3 PROTEIN; SUZ12 PROTEIN; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

EID: 84862907593     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10725     Document Type: Article
Times cited : (1327)

References (43)
  • 1
    • 40749150603 scopus 로고    scopus 로고
    • Acute lymphoblastic leukaemia
    • DOI 10.1016/S0140-6736(08)60457-2, PII S0140673608604572
    • Pui, C. H., Robison, L. L. & Look, A. T. Acute lymphoblastic leukaemia. Lancet 371, 1030-1043 (2008). (Pubitemid 351389536)
    • (2008) The Lancet , vol.371 , Issue.9617 , pp. 1030-1043
    • Pui, C.-H.1    Robison, L.L.2    Look, A.T.3
  • 2
    • 58749095816 scopus 로고    scopus 로고
    • Early T-cell precursor leukaemia: A subtype of very highrisk acute lymphoblastic leukaemia
    • Coustan-Smith, E. et al. Early T-cell precursor leukaemia: a subtype of very highrisk acute lymphoblastic leukaemia. Lancet Oncol. 10, 147-156 (2009).
    • (2009) Lancet Oncol. , vol.10 , pp. 147-156
    • Coustan-Smith, E.1
  • 3
    • 37549010335 scopus 로고    scopus 로고
    • A Launching the T-cell-lineage developmental programme
    • Rothenberg, E. V., Moore, J. E. & Yui, M. A. Launching the T-cell-lineage developmental programme. Nature Rev. Immunol. 8, 9-21 (2008).
    • (2008) Nature Rev. Immunol. , vol.8 , pp. 9-21
    • Rothenberg, E.V.1    Moore, J.E.2    Yui, M.3
  • 5
    • 79961007031 scopus 로고    scopus 로고
    • CREST maps somatic structural variation in cancer genomes with base-pair resolution
    • Wang, J. et al. CREST maps somatic structural variation in cancer genomes with base-pair resolution. Nature Methods 8, 652-654 (2011).
    • (2011) Nature Methods , vol.8 , pp. 652-654
    • Wang, J.1
  • 6
    • 78650959663 scopus 로고    scopus 로고
    • Massive genomic rearrangement acquired in a single catastrophic event during cancer development
    • Stephens, P. J. et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144, 27-40 (2011).
    • (2011) Cell , vol.144 , pp. 27-40
    • Stephens, P.J.1
  • 7
    • 17044429678 scopus 로고    scopus 로고
    • ETV6: A versatile player in leukemogenesis
    • Bohlander, S. K. ETV6: a versatile player in leukemogenesis. Semin. Cancer Biol. 15, 162-174 (2005).
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 162-174
    • Bohlander, S.K.1
  • 9
    • 21344448655 scopus 로고    scopus 로고
    • Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia
    • Barjesteh van Waalwijk van Doorn-Khosrovani, S. et al. Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia. Oncogene 24, 4129-4137 (2005).
    • (2005) Oncogene , vol.24 , pp. 4129-4137
    • Barjesteh, S.1
  • 16
    • 84862922275 scopus 로고    scopus 로고
    • High rate of FLT3 mutations in adult ETP-ALL
    • Neumann, M. et al. High rate of FLT3 mutations in adult ETP-ALL. ASH Annu. Meet. Abstr. 116, 1031 (2010).
    • (2010) ASH Annu. Meet. Abstr. , vol.116 , pp. 1031
    • Neumann, M.1
  • 17
    • 77950299929 scopus 로고    scopus 로고
    • PHF6 mutations in T-cell acute lymphoblastic leukemia
    • Van Vlierberghe, P. et al. PHF6 mutations in T-cell acute lymphoblastic leukemia. Nature Genet. 42, 338-342 (2010).
    • (2010) Nature Genet. , vol.42 , pp. 338-342
    • Van Vlierberghe, P.1
  • 18
    • 70349232830 scopus 로고    scopus 로고
    • WT1 mutations in T-ALL
    • Tosello, V. et al. WT1 mutations in T-ALL. Blood 114, 1038-1045 (2009).
    • (2009) Blood , vol.114 , pp. 1038-1045
    • Tosello, V.1
  • 19
    • 77954089584 scopus 로고    scopus 로고
    • Array-based genomic resequencing of human leukemia
    • Yamashita, Y. et al. Array-based genomic resequencing of human leukemia. Oncogene 29, 3723-3731 (2010).
    • (2010) Oncogene , vol.29 , pp. 3723-3731
    • Yamashita, Y.1
  • 20
    • 54049107944 scopus 로고    scopus 로고
    • Activatingmutations in humanacutemegakaryoblastic leukemia
    • Malinge, S. et al. Activatingmutations in humanacutemegakaryoblastic leukemia. Blood 112, 4220-4226 (2008).
    • (2008) Blood , vol.112 , pp. 4220-4226
    • Malinge, S.1
  • 21
    • 33745207614 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin in normal and pathogenic T cell development and function
    • DOI 10.1038/ni1360, PII N1360
    • Ziegler, S. F.& Liu, Y. J. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nature Immunol. 7, 709-714 (2006). (Pubitemid 43905869)
    • (2006) Nature Immunology , vol.7 , Issue.7 , pp. 709-714
    • Ziegler, S.F.1    Liu, Y.-J.2
  • 22
    • 70350519430 scopus 로고    scopus 로고
    • Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
    • Russell, L. J. et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood 114, 2688-2698 (2009).
    • (2009) Blood , vol.114 , pp. 2688-2698
    • Russell, L.J.1
  • 23
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitor-and Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan, C. G. et al. Rearrangement of CRLF2 in B-progenitor-and Down syndrome-associated acute lymphoblastic leukemia. Nature Genet. 41, 1243-1246 (2009).
    • (2009) Nature Genet. , vol.41 , pp. 1243-1246
    • Mullighan, C.G.1
  • 24
    • 79956108320 scopus 로고    scopus 로고
    • Gain-of-function mutations in interleukin-7 receptor-a (IL7R) in childhood acute lymphoblastic leukemias
    • Shochat, C. et al. Gain-of-function mutations in interleukin-7 receptor-a (IL7R) in childhood acute lymphoblastic leukemias. J. Exp. Med. 208, 901-908 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 901-908
    • Shochat, C.1
  • 25
    • 79955741414 scopus 로고    scopus 로고
    • MOHITO a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context
    • Kleppe, M., Mentens, N., Tousseyn, T., Wlodarska, I. & Cools, J. MOHITO, a novel mouse cytokine-dependent T-cell line, enables studies of oncogenic signaling in the T-cell context. Haematologica 96, 779-783 (2011).
    • (2011) Haematologica , vol.96 , pp. 779-783
    • Kleppe, M.1    Mentens, N.2    Tousseyn, T.3    Wlodarska, I.4    Cools, J.5
  • 26
    • 77958521763 scopus 로고    scopus 로고
    • Fromthe cradle to the grave: Activities ofGATA-3 throughout T-cell development and differentiation
    • Hosoya, T.,Maillard, I.&Engel, J. D. Fromthe cradle to the grave: activities ofGATA-3 throughout T-cell development and differentiation. Immunol. Rev. 238, 110-125 (2010).
    • (2010) Immunol. Rev. , vol.238 , pp. 110-125
    • Hosoya, T.1    Maillard, I.2    Engel, J.D.3
  • 28
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • DOI 10.1016/S0092-8674(00)80986-1
    • Okuda, T., van Deursen, J., Hiebert, S. W., Grosveld, G. & Downing, J. R. AML1, the target ofmultiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 84, 321-330 (1996). (Pubitemid 26042836)
    • (1996) Cell , vol.84 , Issue.2 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 30
    • 77955715121 scopus 로고    scopus 로고
    • Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1andNRAS in 269 patients with MDS or secondary AML
    • Dicker, F. et al. Mutation analysis for RUNX1, MLL-PTD, FLT3-ITD, NPM1andNRAS in 269 patients with MDS or secondary AML. Leukemia 24, 1528-1532 (2010).
    • (2010) Leukemia , vol.24 , pp. 1528-1532
    • Dicker, F.1
  • 31
    • 79954448043 scopus 로고    scopus 로고
    • RUNX1 mutations in acute myeloid leukemia: Results from a comprehensive genetic and clinical analysis from the AML study group
    • Gaidzik, V. I. et al. RUNX1 mutations in acute myeloid leukemia: results from a comprehensive genetic and clinical analysis from the AML study group. J. Clin. Oncol. 29, 1364-1372 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , pp. 1364-1372
    • Gaidzik, V.I.1
  • 32
    • 57249084078 scopus 로고    scopus 로고
    • Genome profiling of chronic myelomonocytic leukemia: Frequent alterations of RAS and RUNX1 genes
    • Gelsi-Boyer, V. et al. Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1 genes. BMC Cancer 8, 299 (2008).
    • (2008) BMC Cancer , vol.8 , pp. 299
    • Gelsi-Boyer, V.1
  • 33
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • Margueron, R. & Reinberg, D. The Polycomb complex PRC2 and its mark in life. Nature 469, 343-349 (2011).
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 34
    • 75749124332 scopus 로고    scopus 로고
    • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
    • Morin, R. D. et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nature Genet. 42, 181-185 (2010).
    • (2010) Nature Genet. , vol.42 , pp. 181-185
    • Morin, R.D.1
  • 36
    • 0342906570 scopus 로고    scopus 로고
    • Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations
    • Hong, S. E. et al. Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations. Nature Genet. 26, 93-96 (2000).
    • (2000) Nature Genet. , vol.26 , pp. 93-96
    • Hong, S.E.1
  • 37
    • 33750353888 scopus 로고    scopus 로고
    • Reverse engineering cellular networks
    • Margolin, A. A. et al. Reverse engineering cellular networks. Nature Protocols 1, 662-671 (2006).
    • (2006) Nature Protocols , vol.1 , pp. 662-671
    • Margolin, A.A.1
  • 38
    • 78651486442 scopus 로고    scopus 로고
    • Densely interconnected transcriptional circuits control cell states in human hematopoiesis
    • Novershtern, N. et al. Densely interconnected transcriptional circuits control cell states in human hematopoiesis. Cell 144, 296-309 (2011).
    • (2011) Cell , vol.144 , pp. 296-309
    • Novershtern, N.1
  • 39
    • 79960106880 scopus 로고    scopus 로고
    • Isolation of single human hematopoietic stem cells capable of longterm multilineage engraftment
    • Notta, F. et al. Isolation of single human hematopoietic stem cells capable of longterm multilineage engraftment. Science 333, 218-221 (2011).
    • (2011) Science , vol.333 , pp. 218-221
    • Notta, F.1
  • 40
    • 80052468964 scopus 로고    scopus 로고
    • Stemcell gene expression programs influence clinical outcome in human leukemia
    • Eppert, K. et al. Stemcell gene expression programs influence clinical outcome in human leukemia. Nature Med. 17, 1086-1093 (2011).
    • (2011) Nature Med. , vol.17 , pp. 1086-1093
    • Eppert, K.1
  • 41
    • 58749109707 scopus 로고    scopus 로고
    • Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
    • Mullighan, C. G. et al. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N. Engl. J. Med. 360, 470-480 (2009).
    • (2009) N. Engl. J. Med. , vol.360 , pp. 470-480
    • Mullighan, C.G.1
  • 42
    • 0036814971 scopus 로고    scopus 로고
    • Molecular genetics of human leukemias: New insights into therapy
    • Gilliland, D. G. Molecular genetics of human leukemias: new insights into therapy. Semin. Hematol. 39, 6-11 (2002). (Pubitemid 35417143)
    • (2002) Seminars in Hematology , vol.39 , Issue.SUPPL. 3 , pp. 6-11
    • Gilliland, D.G.1
  • 43
    • 69649109364 scopus 로고    scopus 로고
    • Circos: An information aesthetic for comparative genomics
    • Krzywinski, M. et al. Circos: an information aesthetic for comparative genomics. Genome Res. 19, 1639-1645 (2009).
    • (2009) Genome Res. , vol.19 , pp. 1639-1645
    • Krzywinski, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.