-
1
-
-
79955531730
-
Histone lysine methylation and demethylation pathways in cancer
-
R.A. Varier, H.T. Timmers, Histone lysine methylation and demethylation pathways in cancer, Biochim. Biophys. Acta (2010).
-
(2010)
Biochim. Biophys. Acta.
-
-
Varier, R.A.1
Timmers, H.T.2
-
3
-
-
78049275346
-
Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function
-
A.K. Lucio-Eterovic, M.M. Singh, J.E. Gardner, C.S. Veerappan, J.C. Rice, P.B. Carpenter, Role for the nuclear receptor-binding SET domain protein 1 (NSD1) methyltransferase in coordinating lysine 36 methylation at histone 3 with RNA polymerase II function, Proc. Natl. Acad. Sci. U. S. A. 107 (2010) 16952-16957.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 16952-16957
-
-
Lucio-Eterovic, A.K.1
Singh, M.M.2
Gardner, J.E.3
Veerappan, C.S.4
Rice, J.C.5
Carpenter, P.B.6
-
4
-
-
34347392874
-
NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis
-
G.G. Wang, L. Cai, M.P. Pasillas, M.P. Kamps, NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis, Nat. Cell Biol. 9 (2007) 804-812.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 804-812
-
-
Wang, G.G.1
Cai, L.2
Pasillas, M.P.3
Kamps, M.P.4
-
5
-
-
85030573958
-
-
UniProtKB, Q96L73 (NSD1_HUMAN) Reviewed, UniProtKB/Swiss-Prot, in
-
UniProtKB, Q96L73 (NSD1_HUMAN) Reviewed, UniProtKB/Swiss-Prot, in, 2011
-
(2011)
-
-
-
6
-
-
64549161949
-
NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11; p15) and expression pattern of NSD family genes
-
T. Taketani, T. Taki, H. Nakamura, M. Taniwaki, J. Masuda, Y. Hayashi, NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11; p15) and expression pattern of NSD family genes, Cancer Genet. Cytogenet. 190 (2009) 108-112.
-
(2009)
Cancer Genet. Cytogenet.
, vol.190
, pp. 108-112
-
-
Taketani, T.1
Taki, T.2
Nakamura, H.3
Taniwaki, M.4
Masuda, J.5
Hayashi, Y.6
-
7
-
-
78049480691
-
GeneCards Version 3: the human gene integrator
-
(Oxford) 2010
-
M. Safran, I. Dalah, J. Alexander, N. Rosen, T. Iny Stein, M. Shmoish, N. Nativ, I. Bahir, T. Doniger, H. Krug, A. Sirota-Madi, T. Olender, Y. Golan, G. Stelzer, A. Harel, D. Lancet, GeneCards Version 3: the human gene integrator, Database (Oxford) 2010 (2010) baq020.
-
(2010)
Database
-
-
Safran, M.1
Dalah, I.2
Alexander, J.3
Rosen, N.4
Iny Stein, T.5
Shmoish, M.6
Nativ, N.7
Bahir, I.8
Doniger, T.9
Krug, H.10
Sirota-Madi, A.11
Olender, T.12
Golan, Y.13
Stelzer, G.14
Harel, A.15
Lancet, D.16
-
8
-
-
13544267780
-
Evaluation of NSD2 and NSD3 in overgrowth syndromes
-
J. Douglas, K. Coleman, K. Tatton-Brown, H.E. Hughes, I.K. Temple, T.R. Cole, N. Rahman, Evaluation of NSD2 and NSD3 in overgrowth syndromes, Eur. J. Hum. Genet. 13 (2005) 150-153.
-
(2005)
Eur. J. Hum. Genet.
, vol.13
, pp. 150-153
-
-
Douglas, J.1
Coleman, K.2
Tatton-Brown, K.3
Hughes, H.E.4
Temple, I.K.5
Cole, T.R.6
Rahman, N.7
-
9
-
-
0032526951
-
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators
-
N. Huang, E. vom Baur, J.M. Garnier, T. Lerouge, J.L. Vonesch, Y. Lutz, P. Chambon, R. Losson, Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators, EMBO J. 17 (1998) 3398-3412.
-
(1998)
EMBO J
, vol.17
, pp. 3398-3412
-
-
Huang, N.1
vom Baur, E.2
Garnier, J.M.3
Lerouge, T.4
Vonesch, J.L.5
Lutz, Y.6
Chambon, P.7
Losson, R.8
-
10
-
-
0037217478
-
NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes
-
J. Douglas, S. Hanks, I.K. Temple, S. Davies, A. Murray, M. Upadhyaya, S. Tomkins, H.E. Hughes, T.R. Cole, N. Rahman, NSD1 mutations are the major cause of Sotos syndrome and occur in some cases of Weaver syndrome but are rare in other overgrowth phenotypes, Am. J. Hum. Genet. 72 (2003) 132-143.
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 132-143
-
-
Douglas, J.1
Hanks, S.2
Temple, I.K.3
Davies, S.4
Murray, A.5
Upadhyaya, M.6
Tomkins, S.7
Hughes, H.E.8
Cole, T.R.9
Rahman, N.10
-
11
-
-
18544384537
-
Haploinsufficiency of NSD1 causes Sotos syndrome
-
N. Kurotaki, K. Imaizumi, N. Harada, M. Masuno, T. Kondoh, T. Nagai, H. Ohashi, K. Naritomi, M. Tsukahara, Y. Makita, T. Sugimoto, T. Sonoda, T. Hasegawa, Y. Chinen, H.A. Tomita Ha, A. Kinoshita, T. Mizuguchi, K. Yoshiura Ki, T. Ohta, T. Kishino, Y. Fukushima, N. Niikawa, N. Matsumoto, Haploinsufficiency of NSD1 causes Sotos syndrome, Nat. Genet. 30 (2002) 365-366.
-
(2002)
Nat. Genet.
, vol.30
, pp. 365-366
-
-
Kurotaki, N.1
Imaizumi, K.2
Harada, N.3
Masuno, M.4
Kondoh, T.5
Nagai, T.6
Ohashi, H.7
Naritomi, K.8
Tsukahara, M.9
Makita, Y.10
Sugimoto, T.11
Sonoda, T.12
Hasegawa, T.13
Chinen, Y.14
Tomita Ha, H.A.15
Kinoshita, A.16
Mizuguchi, T.17
Yoshiura Ki, K.18
Ohta, T.19
Kishino, T.20
Fukushima, Y.21
Niikawa, N.22
Matsumoto, N.23
more..
-
12
-
-
0031779421
-
WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma
-
I. Stec, T.J. Wright, G.J. van Ommen, P.A. de Boer, A. van Haeringen, A.F. Moorman, M.R. Altherr, J.T. den Dunnen, WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma, Hum. Mol. Genet. 7 (1998) 1071-1082.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 1071-1082
-
-
Stec, I.1
Wright, T.J.2
van Ommen, G.J.3
de Boer, P.A.4
van Haeringen, A.5
Moorman, A.F.6
Altherr, M.R.7
den Dunnen, J.T.8
-
13
-
-
8044224043
-
A transcript map of the newly defined 165 kb Wolf-Hirschhorn syndrome critical region
-
T.J. Wright, D.O. Ricke, K. Denison, S. Abmayr, P.D. Cotter, K. Hirschhorn, M. Keinanen, D. McDonald-McGinn, M. Somer, N. Spinner, T. Yang-Feng, E. Zackai, M. R. Altherr, A transcript map of the newly defined 165 kb Wolf-Hirschhorn syndrome critical region, Hum. Mol. Genet. 6 (1997) 317-324.
-
(1997)
Hum. Mol. Genet.
, vol.6
, pp. 317-324
-
-
Wright, T.J.1
Ricke, D.O.2
Denison, K.3
Abmayr, S.4
Cotter, P.D.5
Hirschhorn, K.6
Keinanen, M.7
McDonald-McGinn, D.8
Somer, M.9
Spinner, N.10
Yang-Feng, T.11
Zackai, E.12
Altherr, M.R.13
-
14
-
-
67650461956
-
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome
-
K. Nimura, K. Ura, H. Shiratori, M. Ikawa, M. Okabe, R.J. Schwartz, Y. Kaneda, A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome, Nature 460 (2009) 287-291.
-
(2009)
Nature
, vol.460
, pp. 287-291
-
-
Nimura, K.1
Ura, K.2
Shiratori, H.3
Ikawa, M.4
Okabe, M.5
Schwartz, R.J.6
Kaneda, Y.7
-
15
-
-
79955506975
-
The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors
-
H.R. Hudlebusch, E. Santoni-Rugiu, R. Simon, E. Ralfkiaer, H.H. Rossing, J.V. Johansen, M. Jorgensen, G. Sauter, K. Helin, The histone methyltransferase and putative oncoprotein MMSET is overexpressed in a large variety of human tumors, Clin. Cancer Res. 17 (2011) 2919-2933.
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 2919-2933
-
-
Hudlebusch, H.R.1
Santoni-Rugiu, E.2
Simon, R.3
Ralfkiaer, E.4
Rossing, H.H.5
Johansen, J.V.6
Jorgensen, M.7
Sauter, G.8
Helin, K.9
-
16
-
-
77957012141
-
Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells
-
F. Zhao, Y. Chen, R. Li, R. Zeng, L. Wen, Y. Liu, C. Zhang, Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells, Eur. J. Pharmacol. (2010).
-
(2010)
Eur. J. Pharmacol.
-
-
Zhao, F.1
Chen, Y.2
Li, R.3
Zeng, R.4
Wen, L.5
Liu, Y.6
Zhang, C.7
-
17
-
-
0037093259
-
NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15)
-
R. Rosati, R. La Starza, A. Veronese, A. Aventin, C. Schwienbacher, T. Vallespi, M. Negrini, M.F. Martelli, C. Mecucci, NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15), Blood 99 (2002) 3857-3860.
-
(2002)
Blood
, vol.99
, pp. 3857-3860
-
-
Rosati, R.1
La Starza, R.2
Veronese, A.3
Aventin, A.4
Schwienbacher, C.5
Vallespi, T.6
Negrini, M.7
Martelli, M.F.8
Mecucci, C.9
-
18
-
-
42449161943
-
The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor
-
J. Marango, M. Shimoyama, H. Nishio, J.A. Meyer, D.-J. Min, A. Sirulnik, Y. Martinez-Martinez, M. Chesi, P.L. Bergsagel, M.-M. Zhou, S. Waxman, B.A. Leibovitch, M.J. Walsh, J.D. Licht, The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor, Blood 111 (2008) 3145-3154.
-
(2008)
Blood
, vol.111
, pp. 3145-3154
-
-
Marango, J.1
Shimoyama, M.2
Nishio, H.3
Meyer, J.A.4
Min, D.-J.5
Sirulnik, A.6
Martinez-Martinez, Y.7
Chesi, M.8
Bergsagel, P.L.9
Zhou, M.-M.10
Waxman, S.11
Leibovitch, B.A.12
Walsh, M.J.13
Licht, J.D.14
-
19
-
-
0037599617
-
NSD1 is essential for early postimplantation development and has a catalytically active SET domain
-
G.V. Rayasam, O. Wendling, P.-O. Angrand, M. Mark, K. Niederreither, L. Song, T. Lerouge, G.L. Hager, P. Chambon, R. Losson, NSD1 is essential for early postimplantation development and has a catalytically active SET domain, Embo J. 22 (2003) 3153-3163.
-
(2003)
Embo J
, vol.22
, pp. 3153-3163
-
-
Rayasam, G.V.1
Wendling, O.2
Angrand, P.-O.3
Mark, M.4
Niederreither, K.5
Song, L.6
Lerouge, T.7
Hager, G.L.8
Chambon, P.9
Losson, R.10
-
20
-
-
69149100639
-
Acquired copy number alterations in adult acute myeloid leukemia genomes
-
M.J. Walter, J.E. Payton, R.E. Ries, W.D. Shannon, H. Deshmukh, Y. Zhao, J. Baty, S. Heath, P. Westervelt, M.A. Watson, M.H. Tomasson, R. Nagarajan, B.P. O'Gara, C.D. Bloomfield, K. Mrozek, R.R. Selzer, T.A. Richmond, J. Kitzman, J. Geoghegan, P.S. Eis, R. Maupin, R.S. Fulton, M. McLellan, R.K. Wilson, E.R. Mardis, D.C. Link, T.A. Graubert, J.F. DiPersio, T.J. Ley, Acquired copy number alterations in adult acute myeloid leukemia genomes, Proc. Natl. Acad. Sci. U .S. A. 106 (2009) 12950-12955.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 12950-12955
-
-
Walter, M.J.1
Payton, J.E.2
Ries, R.E.3
Shannon, W.D.4
Deshmukh, H.5
Zhao, Y.6
Baty, J.7
Heath, S.8
Westervelt, P.9
Watson, M.A.10
Tomasson, M.H.11
Nagarajan, R.12
O'Gara, B.P.13
Bloomfield, C.D.14
Mrozek, K.15
Selzer, R.R.16
Richmond, T.A.17
Kitzman, J.18
Geoghegan, J.19
Eis, P.S.20
Maupin, R.21
Fulton, R.S.22
McLellan, M.23
Wilson, R.K.24
Mardis, E.R.25
Link, D.C.26
Graubert, T.A.27
DiPersio, J.F.28
Ley, T.J.29
more..
-
21
-
-
0036170767
-
Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression
-
B.D. Strahl, P.A. Grant, S.D. Briggs, Z.-W. Sun, J.R. Bone, J.A. Caldwell, S. Mollah, R.G. Cook, J. Shabanowitz, D.F. Hunt, C.D. Allis, Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression, Mol. Cell. Biol. 22 (2002) 1298-1306.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1298-1306
-
-
Strahl, B.D.1
Grant, P.A.2
Briggs, S.D.3
Sun, Z.-W.4
Bone, J.R.5
Caldwell, J.A.6
Mollah, S.7
Cook, R.G.8
Shabanowitz, J.9
Hunt, D.F.10
Allis, C.D.11
-
22
-
-
67349115185
-
The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcription
-
H.B. Kang, Y. Choi, J.M. Lee, K.C. Choi, H.C. Kim, J.Y. Yoo, Y.H. Lee, H.G. Yoon, The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcription, FEBS Lett. 583 (2009) 1880-1886.
-
(2009)
FEBS Lett
, vol.583
, pp. 1880-1886
-
-
Kang, H.B.1
Choi, Y.2
Lee, J.M.3
Choi, K.C.4
Kim, H.C.5
Yoo, J.Y.6
Lee, Y.H.7
Yoon, H.G.8
-
24
-
-
58149232433
-
MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells
-
J.L. Brito, B. Walker, M. Jenner, N.J. Dickens, N.J. Brown, F.M. Ross, A. Avramidou, J. A. Irving, D. Gonzalez, F.E. Davies, G.J. Morgan, MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells, Haematologica 94 (2009) 78-86.
-
(2009)
Haematologica
, vol.94
, pp. 78-86
-
-
Brito, J.L.1
Walker, B.2
Jenner, M.3
Dickens, N.J.4
Brown, N.J.5
Ross, F.M.6
Avramidou, A.7
Irving, J.A.8
Gonzalez, D.9
Davies, F.E.10
Morgan, G.J.11
-
25
-
-
71749121455
-
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate
-
Y. Li, P. Trojer, C.F. Xu, P. Cheung, A. Kuo, W.J. Drury III, Q. Qiao, T.A. Neubert, R.M. Xu, O. Gozani, D. Reinberg, The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate, J. Biol. Chem. 284 (2009) 34283-34295.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 34283-34295
-
-
Li, Y.1
Trojer, P.2
Xu, C.F.3
Cheung, P.4
Kuo, A.5
Drury III, W.J.6
Qiao, Q.7
Neubert, T.A.8
Xu, R.M.9
Gozani, O.10
Reinberg, D.11
-
26
-
-
0035872769
-
NSD3, a new SET domain-containing gene, Maps to 8p12 and is amplified in human breast cancer cell lines
-
P.-O. Angrand, F. Apiou, A.F. Stewart, B. Dutrillaux, R. Losson, P. Chambon, NSD3, a new SET domain-containing gene, Maps to 8p12 and is amplified in human breast cancer cell lines, Genomics 74 (2001) 79-88.
-
(2001)
Genomics
, vol.74
, pp. 79-88
-
-
Angrand, P.-O.1
Apiou, F.2
Stewart, A.F.3
Dutrillaux, B.4
Losson, R.5
Chambon, P.6
-
27
-
-
22144433675
-
High-resolution genomic profiles of human lung cancer
-
G. Tonon, K.K. Wong, G. Maulik, C. Brennan, B. Feng, Y. Zhang, D.B. Khatry, A. Protopopov, M.J. You, A.J. Aguirre, E.S. Martin, Z. Yang, H. Ji, L. Chin, R.A. Depinho, High-resolution genomic profiles of human lung cancer, Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 9625-9630.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 9625-9630
-
-
Tonon, G.1
Wong, K.K.2
Maulik, G.3
Brennan, C.4
Feng, B.5
Zhang, Y.6
Khatry, D.B.7
Protopopov, A.8
You, M.J.9
Aguirre, A.J.10
Martin, E.S.11
Yang, Z.12
Ji, H.13
Chin, L.14
Depinho, R.A.15
-
28
-
-
0035872769
-
NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines
-
P.O. Angrand, F. Apiou, A.F. Stewart, B. Dutrillaux, R. Losson, P. Chambon, NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines, Genomics 74 (2001) 79-88.
-
(2001)
Genomics
, vol.74
, pp. 79-88
-
-
Angrand, P.O.1
Apiou, F.2
Stewart, A.F.3
Dutrillaux, B.4
Losson, R.5
Chambon, P.6
-
29
-
-
65549155761
-
A transcriptional sketch of a primary human breast cancer by 454 deep sequencing
-
A. Guffanti, M. Iacono, P. Pelucchi, N. Kim, G. Solda, L.J. Croft, R.J. Taft, E. Rizzi, M. Askarian-Amiri, R.J. Bonnal, M. Callari, F. Mignone, G. Pesole, G. Bertalot, L.R. Bernardi, A. Albertini, C. Lee, J.S. Mattick, I. Zucchi, G. De Bellis, A transcriptional sketch of a primary human breast cancer by 454 deep sequencing, B.M.C. Genomics 10 (2009) 163.
-
(2009)
B. M. C. Genomics
, vol.10
, pp. 163
-
-
Guffanti, A.1
Iacono, M.2
Pelucchi, P.3
Kim, N.4
Solda, G.5
Croft, L.J.6
Taft, R.J.7
Rizzi, E.8
Askarian-Amiri, M.9
Bonnal, R.J.10
Callari, M.11
Mignone, F.12
Pesole, G.13
Bertalot, G.14
Bernardi, L.R.15
Albertini, A.16
Lee, C.17
Mattick, J.S.18
Zucchi, I.19
De Bellis, G.20
more..
-
30
-
-
52049083886
-
Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer
-
I. Bernard-Pierrot, N.g. Gruel, N. Stransky, A. Vincent-Salomon, F. Reyal, V. Raynal, C.l. Vallot, G.l. Pierron, F.o. Radvanyi, O. Delattre, Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer, Cancer Res. 68 (2008) 7165-7175.
-
(2008)
Cancer Res
, vol.68
, pp. 7165-7175
-
-
Bernard-Pierrot, I.1
Gruel, N.G.2
Stransky, N.3
Vincent-Salomon, A.4
Reyal, F.5
Raynal, V.6
Vallot, C.L.7
Pierron, C.L.8
Radvanyi, F.O.9
Delattre, O.10
-
31
-
-
0037172665
-
Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain
-
Q. Feng, H. Wang, H.H. Ng, H. Erdjument-Bromage, P. Tempst, K. Struhl, Y. Zhang, Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain, Curr. Biol. 12 (2002) 1052-1058.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1052-1058
-
-
Feng, Q.1
Wang, H.2
Ng, H.H.3
Erdjument-Bromage, H.4
Tempst, P.5
Struhl, K.6
Zhang, Y.7
-
32
-
-
5644261221
-
Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase
-
K. Sawada, Z. Yang, J.R. Horton, R.E. Collins, X. Zhang, X. Cheng, Structure of the conserved core of the yeast Dot1p, a nucleosomal histone H3 lysine 79 methyltransferase, J. Biol. Chem. 279 (2004) 43296-43306.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 43296-43306
-
-
Sawada, K.1
Yang, Z.2
Horton, J.R.3
Collins, R.E.4
Zhang, X.5
Cheng, X.6
-
33
-
-
0344837759
-
Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase
-
J. Min, Q. Feng, Z. Li, Y. Zhang, R.M. Xu, Structure of the catalytic domain of human DOT1L, a non-SET domain nucleosomal histone methyltransferase, Cell 112 (2003) 711-723.
-
(2003)
Cell
, vol.112
, pp. 711-723
-
-
Min, J.1
Feng, Q.2
Li, Z.3
Zhang, Y.4
Xu, R.M.5
-
34
-
-
0037979272
-
Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II
-
N.J. Krogan, M. Kim, A. Tong, A. Golshani, G. Cagney, V. Canadien, D.P. Richards, B. K. Beattie, A. Emili, C. Boone, A. Shilatifard, S. Buratowski, J. Greenblatt, Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II, Mol. Cell Biol. 23 (2003) 4207-4218.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 4207-4218
-
-
Krogan, N.J.1
Kim, M.2
Tong, A.3
Golshani, A.4
Cagney, G.5
Canadien, V.6
Richards, D.P.7
Beattie, B.K.8
Emili, A.9
Boone, C.10
Shilatifard, A.11
Buratowski, S.12
Greenblatt, J.13
-
35
-
-
0034610814
-
The language of covalent histone modifications
-
B.D. Strahl, C.D. Allis, The language of covalent histone modifications, Nature 403 (2000) 41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
36
-
-
79955473684
-
OPERating on chromatin, a colorful language where context matters
-
K.E. Gardner, C.D. Allis, B.D. Strahl, OPERating on chromatin, a colorful language where context matters, J. Mol. Biol. 409 (2011) 36-46.
-
(2011)
J. Mol. Biol.
, vol.409
, pp. 36-46
-
-
Gardner, K.E.1
Allis, C.D.2
Strahl, B.D.3
-
37
-
-
36849084465
-
Linking the epigenetic 'language' of covalent histone modifications to cancer
-
S.B. Hake, A. Xiao, C.D. Allis, Linking the epigenetic 'language' of covalent histone modifications to cancer, Br. J. Cancer 96 (2007) R31-R39 Suppl.
-
(2007)
Br. J. Cancer
, vol.96
, Issue.SUPPL.
-
-
Hake, S.B.1
Xiao, A.2
Allis, C.D.3
-
38
-
-
33646203168
-
Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase
-
C. Qian, X. Wang, K. Manzur, Sachchidanand, A. Farooq, L. Zeng, R. Wang, M.M. Zhou, Structural insights of the specificity and catalysis of a viral histone H3 lysine 27 methyltransferase, J. Mol. Biol. 359 (2006) 86-96.
-
(2006)
J. Mol. Biol.
, vol.359
, pp. 86-96
-
-
Qian, C.1
Wang, X.2
Manzur, K.3
Sachchidanand4
Farooq, A.5
Zeng, L.6
Wang, R.7
Zhou, M.M.8
-
39
-
-
34547433238
-
Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity
-
H.B. Guo, H. Guo, Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity, Proc. Natl. Acad. Sci. U. S. A. 104 (2007) 8797-8802.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 8797-8802
-
-
Guo, H.B.1
Guo, H.2
-
40
-
-
44449162039
-
Enzymatic mechanism and product specificity of SETdomain protein lysine methyltransferases
-
X. Zhang, T.C. Bruice, Enzymatic mechanism and product specificity of SETdomain protein lysine methyltransferases, Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 5728-5732.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 5728-5732
-
-
Zhang, X.1
Bruice, T.C.2
-
41
-
-
45749140396
-
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8
-
X. Zhang, T.C. Bruice, Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8, Biochemistry 47 (2008) 6671-6677.
-
(2008)
Biochemistry
, vol.47
, pp. 6671-6677
-
-
Zhang, X.1
Bruice, T.C.2
-
42
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
G. Schotta, M. Lachner, K. Sarma, A. Ebert, R. Sengupta, G. Reuter, D. Reinberg, T. Jenuwein, A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin, Genes Dev. 18 (2004) 1251-1262.
-
(2004)
Genes Dev
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
Reinberg, D.7
Jenuwein, T.8
-
43
-
-
79960303020
-
The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation
-
Q. Qiao, Y. Li, Z. Chen, M. Wang, D. Reinberg, R.M. Xu, The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation, J. Biol. Chem. (2010).
-
(2010)
J. Biol. Chem.
-
-
Qiao, Q.1
Li, Y.2
Chen, Z.3
Wang, M.4
Reinberg, D.5
Xu, R.M.6
-
44
-
-
76249100563
-
Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65
-
T. Lu, M.W. Jackson, B. Wang, M. Yang, M.R. Chance, M. Miyagi, A.V. Gudkov, G.R. Stark, Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65, Proc. Natl. Acad. Sci. U. S. A. 107 (2010) 46-51.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 46-51
-
-
Lu, T.1
Jackson, M.W.2
Wang, B.3
Yang, M.4
Chance, M.R.5
Miyagi, M.6
Gudkov, A.V.7
Stark, G.R.8
-
45
-
-
70349490830
-
Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB
-
T. Lu, M.W. Jackson, A.D. Singhi, E.S. Kandel, M. Yang, Y. Zhang, A.V. Gudkov, G.R. Stark, Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB, Proc. Natl. Acad. Sci. U. S. A. 106 (2009) 16339-16344.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 16339-16344
-
-
Lu, T.1
Jackson, M.W.2
Singhi, A.D.3
Kandel, E.S.4
Yang, M.5
Zhang, Y.6
Gudkov, A.V.7
Stark, G.R.8
-
46
-
-
50249167778
-
p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo
-
W.W. Tsai, T.T. Nguyen, Y. Shi, M.C. Barton, p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo, Mol. Cell Biol. 28 (2008) 5139-5146.
-
(2008)
Mol. Cell Biol.
, vol.28
, pp. 5139-5146
-
-
Tsai, W.W.1
Nguyen, T.T.2
Shi, Y.3
Barton, M.C.4
-
47
-
-
79551665780
-
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
-
H. Pei, L. Zhang, K. Luo, Y. Qin, M. Chesi, F. Fei, P.L. Bergsagel, L. Wang, Z. You, Z. Lou, MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites, Nature 470 (2011) 124-128.
-
(2011)
Nature
, vol.470
, pp. 124-128
-
-
Pei, H.1
Zhang, L.2
Luo, K.3
Qin, Y.4
Chesi, M.5
Fei, F.6
Bergsagel, P.L.7
Wang, L.8
You, Z.9
Lou, Z.10
-
48
-
-
33646412094
-
Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity
-
S.M. Kim, H.J. Kee, G.H. Eom, N.W. Choe, J.Y. Kim, Y.S. Kim, S.K. Kim, H. Kook, S.B. Seo, Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity, Biochem. Biophys. Res. Commun. 345 (2006) 318-323.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.345
, pp. 318-323
-
-
Kim, S.M.1
Kee, H.J.2
Eom, G.H.3
Choe, N.W.4
Kim, J.Y.5
Kim, Y.S.6
Kim, S.K.7
Kook, H.8
Seo, S.B.9
-
49
-
-
77955497653
-
Human LSD2/KDM1b/ AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation
-
R. Fang, A.J. Barbera, Y. Xu, M. Rutenberg, T. Leonor, Q. Bi, F. Lan, P. Mei, G.C. Yuan, C. Lian, J. Peng, D. Cheng, G. Sui, U.B. Kaiser, Y. Shi, Y.G. Shi, Human LSD2/KDM1b/ AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation, Mol. Cell. 39 (2010) 222-233.
-
(2010)
Mol. Cell.
, vol.39
, pp. 222-233
-
-
Fang, R.1
Barbera, A.J.2
Xu, Y.3
Rutenberg, M.4
Leonor, T.5
Bi, Q.6
Lan, F.7
Mei, P.8
Yuan, G.C.9
Lian, C.10
Peng, J.11
Cheng, D.12
Sui, G.13
Kaiser, U.B.14
Shi, Y.15
Shi, Y.G.16
-
50
-
-
39749190633
-
Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly
-
J.D. Buxbaum, G. Cai, G. Nygren, P. Chaste, R. Delorme, J. Goldsmith, M. Rastam, J. M. Silverman, E. Hollander, C. Gillberg, M. Leboyer, C. Betancur, Mutation analysis of the NSD1 gene in patients with autism spectrum disorders and macrocephaly, B.M.C. Med. Genet. 8 (2007) 68.
-
(2007)
B. M. C. Med. Genet.
, vol.8
, pp. 68
-
-
Buxbaum, J.D.1
Cai, G.2
Nygren, G.3
Chaste, P.4
Delorme, R.5
Goldsmith, J.6
Rastam, M.7
Silverman, J.M.8
Hollander, E.9
Gillberg, C.10
Leboyer, M.11
Betancur, C.12
-
51
-
-
39149084348
-
Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas
-
J. Li, C. Yin, H. Okamoto, H. Mushlin, B.M. Balgley, C.S. Lee, K. Yuan, B. Ikejiri, S. Glasker, A.O. Vortmeyer, E.H. Oldfield, R.J. Weil, Z. Zhuang, Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas, Neuro. Oncol. 10 (2008) 45-51.
-
(2008)
Neuro. Oncol.
, vol.10
, pp. 45-51
-
-
Li, J.1
Yin, C.2
Okamoto, H.3
Mushlin, H.4
Balgley, B.M.5
Lee, C.S.6
Yuan, K.7
Ikejiri, B.8
Glasker, S.9
Vortmeyer, A.O.10
Oldfield, E.H.11
Weil, R.J.12
Zhuang, Z.13
-
52
-
-
78650978001
-
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells
-
E. Martinez-Garcia, R. Popovic, D.J. Min, S.M. Sweet, P.M. Thomas, L. Zamdborg, A. Heffner, C. Will, L. Lamy, L.M. Staudt, D.L. Levens, N.L. Kelleher, J.D. Licht, The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells, Blood 117 (2011) 211-220.
-
(2011)
Blood
, vol.117
, pp. 211-220
-
-
Martinez-Garcia, E.1
Popovic, R.2
Min, D.J.3
Sweet, S.M.4
Thomas, P.M.5
Zamdborg, L.6
Heffner, A.7
Will, C.8
Lamy, L.9
Staudt, L.M.10
Levens, D.L.11
Kelleher, N.L.12
Licht, J.D.13
-
53
-
-
55949109901
-
Cancer treatment of the future: inhibitors of histone methyltransferases
-
A. Spannhoff, W. Sippl, M. Jung, Cancer treatment of the future: inhibitors of histone methyltransferases, Int. J. Biochem. Cell Biol. 41 (2009) 4-11.
-
(2009)
Int. J. Biochem. Cell Biol.
, vol.41
, pp. 4-11
-
-
Spannhoff, A.1
Sippl, W.2
Jung, M.3
-
54
-
-
70349780606
-
The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors
-
A. Spannhoff, A.T. Hauser, R. Heinke, W. Sippl, M. Jung, The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors, Chem. Med. Chem. 4 (2009) 1568-1582.
-
(2009)
Chem. Med. Chem.
, vol.4
, pp. 1568-1582
-
-
Spannhoff, A.1
Hauser, A.T.2
Heinke, R.3
Sippl, W.4
Jung, M.5
-
55
-
-
77952488976
-
Structural biology of human H3K9 methyltransferases
-
H. Wu, J. Min, V.V. Lunin, T. Antoshenko, L. Dombrovski, H. Zeng, A. Allali-Hassani, V. Campagna-Slater, M. Vedadi, C.H. Arrowsmith, A.N. Plotnikov, M. Schapira, Structural biology of human H3K9 methyltransferases, PLoS One 5 (2010) e8570.
-
(2010)
PLoS One
, vol.5
-
-
Wu, H.1
Min, J.2
Lunin, V.V.3
Antoshenko, T.4
Dombrovski, L.5
Zeng, H.6
Allali-Hassani, A.7
Campagna-Slater, V.8
Vedadi, M.9
Arrowsmith, C.H.10
Plotnikov, A.N.11
Schapira, M.12
-
56
-
-
77957770113
-
SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation
-
P.A. Del Rizzo, J.F. Couture, L.M. Dirk, B.S. Strunk, M.S. Roiko, J.S. Brunzelle, R.L. Houtz, R.C. Trievel, SET7/9 catalytic mutants reveal the role of active site water molecules in lysine multiple methylation, J. Biol. Chem. 285 (2010) 31849-31858.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 31849-31858
-
-
Del Rizzo, P.A.1
Couture, J.F.2
Dirk, L.M.3
Strunk, B.S.4
Roiko, M.S.5
Brunzelle, J.S.6
Houtz, R.L.7
Trievel, R.C.8
-
57
-
-
22344454519
-
Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase
-
J.F. Couture, E. Collazo, J.S. Brunzelle, R.C. Trievel, Structural and functional analysis of SET8, a histone H4 Lys-20 methyltransferase, Genes Dev. 19 (2005) 1455-1465.
-
(2005)
Genes Dev
, vol.19
, pp. 1455-1465
-
-
Couture, J.F.1
Collazo, E.2
Brunzelle, J.S.3
Trievel, R.C.4
|