Phosphoribosyl diphosphate (PRPP): Biosynthesis, enzymology, utilization, and metabolic significance

Microbiology and Molecular Biology Reviews

Volumn 81, Issue 1, 2017, Pages

  Hove Jensen, Bjarne ^a,b   Andersen, Kasper R ^b   Kilstrup, Mogens ^a   Martinussen, Jan ^a   Switzer, Robert L ^c   Willemoës, Martin ^d  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Amino acid metabolism; Diphosphoryl transfer; Nucleotide metabolism; Phosphoribosyl pyrophosphate; Protein structure function

Indexed keywords

ALPHA PHOSPHATE; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BACTERIAL PROTEIN; BETA PHOSPHATE; CARBAMOYL PHOSPHATE SYNTHASE; COCARBOXYLASE; DNA BINDING PROTEIN; DNAR PROTEIN; GAMMA PHOSPHATE; GUANOSINE TRIPHOSPHATE; HISTIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PENTOSE PHOSPHATE; PHOSPHATE; PHOSPHORIBOSYL BISPHOSPHATE PHOSPHOKINASE; PHOSPHORIBOSYL DIPHOSPHATE; PHOSPHORIBOSYL DIPHOSPHATE SYNTHASE; PHOSPHORIBOSYLTRANSFERASE; PHOSPHOTRANSFERASE; PTERIN DERIVATIVE; PURINE NUCLEOTIDE; PURR PROTEIN; PYRIMIDINE NUCLEOTIDE; PYRR PROTEIN; RIBOFLAVIN DERIVATIVE; RNA BINDING PROTEIN; SYNTHETASE; THIAMINE PYROPHOSPHOKINASE; TRYPTOPHAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; LIPOATE-PROTEIN LIGASE; PEPTIDE SYNTHASE; PHOSPHORIBOSYL PYROPHOSPHATE; PROTOZOAL PROTEIN; RIBOSE PHOSPHATE; RIBOSE-5-PHOSPHATE; RIBOSEPHOSPHATE PYROPHOSPHOKINASE;

ALLOSTERISM; BACTERIAL STRAIN; CATALYSIS; CELL FUNCTION; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; ENZYME SYNTHESIS; ENZYMOLOGY; ESCHERICHIA COLI; FUNGUS; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; GLYCOSIDATION; HUMAN; IN VITRO STUDY; MEDIATOR; METABOLIC REGULATION; MOLECULAR EVOLUTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHYLOGENY; PROTEIN STRUCTURE; PURINE METABOLISM; PURINE SYNTHESIS; PYRIMIDINE METABOLISM; REVIEW; SACCHAROMYCES CEREVISIAE; SALMONELLA ENTERICA; SCHIZOSACCHAROMYCES POMBE; SUBSTITUTION REACTION; YEAST; AMINO ACID SEQUENCE; ARCHAEON; BACTERIUM; BIOSYNTHESIS; CHEMISTRY; ENERGY METABOLISM; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE;

AMINO ACID SEQUENCE; ARCHAEA; BACTERIA; ENERGY METABOLISM; FUNGI; HUMANS; PEPTIDE SYNTHASES; PHOSPHORIBOSYL PYROPHOSPHATE; PROTEIN STRUCTURE, SECONDARY; PROTOZOAN PROTEINS; RIBOSE-PHOSPHATE PYROPHOSPHOKINASE; RIBOSEMONOPHOSPHATES;

EID: 85011589309     PISSN: 10922172     EISSN: 10985557     Source Type: Journal    
DOI: 10.1128/MMBR.00040-16     Document Type: Review

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