Biosynthesis of the arabinogalactan-peptidoglycan complex of Mycobacterium tuberculosis

Glycobiology

Volumn 11, Issue 9, 2001, Pages

  Crick, D C ^a   Mahapatra, S ^a   Brennan, P J ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Arabinan; Isopentenyl diphosphate; Myobacterium tuberculosis; Peptidoglycan; Polyprenyl phosphate

Indexed keywords

ARABINOGALACTAN; BACTERIAL ENZYME; MYCOLIC ACID; PEPTIDOGLYCAN;

ANIMAL CELL; BACTERIAL GENE; BACTERIAL MEMBRANE; BIOSYNTHESIS; CELL STRUCTURE; CELL VIABILITY; CLINICAL RESEARCH; CONTROLLED STUDY; DRUG DEVELOPMENT; DRUG TARGETING; ENZYME ANALYSIS; GENE SEQUENCE; GLYCOPROTEIN SYNTHESIS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROKARYOTE; PROTEIN STRUCTURE; PUBLICATION; SHORT SURVEY; SPECIES DIFFERENCE;

ACTINOBACTERIA (CLASS); ANIMALIA; BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA; UNCULTURED ACTINOMYCETE;

EID: 0034770036     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/11.9.107R     Document Type: Short Survey

References (83)

1. The mechanism of wall synthesis in bacteria. The organization of enzymes and isoprenoid phosphates in the membrane
2. Prenol nomenclature
3. Teichoic acids in cell walls and membranes of bacteria
4. Purification and characterization of 1-deoxyxylulose 5- phosphate synthase from Mycobacterium tuberculosis
5. Mycolic acids: Structure, biosynthesis and physiological functions
6. The cell-wall core of Mycobacterium: Structure, biogenesis and genetics
7. The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol
8. The mycobacterial cell wall: Biosynthesis of arabinogalactan and lipoarabinomannan
9. A new interpretation of the structure of the mycolylarabinogalactan complex of Mycobacterium tuberculosis as revealed through characterization of oligoglycosylalditol fragments by fast-atom nuclear magnetic resonance spectroscopy
10. Identification of the apparent carrier in mycolic acid synthesis
11. Ultrastructure of Mycobacterium tuberculosis
12. The envelope of mycobacteria
13. Can penicillins and other beta-lactam antibiotics be used to treat tuberculosis?
14. Deuterium-labelled isotopomers of 2-C-methyl-D-erythritol as tools for the elucidation of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis
15. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
16. Antituberculosis drug research
17. Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis
18. The envelope layers of mycobacteria with reference to their pathogenicity
19. Predominant structural features of the cell wall arabinogalactan of Mycobacterium tuberculosis as revealed through characterization of oligoglycosyl alditol fragments by gas chromatography/mass spectrometry analyses
20. Conserved sequences in enzymes of the UDP-GlcNAc/MurNAc family are essential in hamster UDP-GlcNAc:dolichol-P GlcNAc-1-P transferase
21. Alteration of a single amino acid residue reverses fosfomycin resistance of recombinant MurA from Mycobacterium tuberculosis
22. Layered murein revisited: A fundamentally new concept of bacterial cell wall structure, biogenesis and function
23. Molecular mechanics of the mycobacterial cell wall: From horizontal layers to vertical scaffolds
24. The anatomy of mycobacteria
25. The outer parts of the mycobacterial envelope as permeability barriers
26. Biosynthesis of 2-C-methyl-D-erythritol, a putative C-5 intermediate in the mevalonate independent pathway for isoprenoid biosynthesis
27. Use of bacteriolytic enzymes in determination of wall, structure and their role in cell metabolism
28. Serine beta-lactamases and penicillin-binding proteins
29. Escherichia coli open reading frame 696 is idi, a nonessential gene encoding isopentenyl diphosphate isomerase
30. Lipids in glycan synthesis
31. Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C- methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2, 4-cyclodiphosphate
32. Biosynthesis of the peptidoglycan of bacterial cell walls. XIX. Isoprenoid alcohol phosphokinase
33. Construction and use of low-copy number T7 expression vectors for purification of problem proteins: Purification of Mycobacterium tuberculosis RmlD and Pseudomonas aeruginosa LasI and RhlI proteins, and RhlI
34. Isoprenoid biosynthesis in bacteria: Two different pathways?
35. UDP-galactofuranose precursor required for formation of the lipopolysaccharide O antigen of Klebsiella pneumoniae serotype O1 is synthesized by the product of the rfbDKPO1 gene
36. Studies on peptides, glycopeptides and antigenic polysaccharide- glycopeptide complexes isolated from an L-11 enzyme lysate of the cell walls of Mycobacterium tuberculosis strain H37Rv
37. Galactan biosynthesis in Mycobacterium tuberculosis: Identification of a bifunctional UDP-galactofuranosyltransferase
38. Formation of 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol from 2-C-methyl-D-erythritol 4-phosphate by 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, a new enzyme in the nonmevalonate pathway
39. Studies on the nonmevalonate pathway: Conversion of 4-(cytidine 5′-diphospho)-2-C-methyl-D-erythritol to its 2-phospho derivative by 4-(cytidine 5′-diphospho)-2-C-methyl-D- erythritol kinase
40. Direct formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose 5-phosphate by 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate
41. A sterol biosynthetic pathway in Mycobacterium
42. Isopentenyl diphosphate biosynthesis via a mevalonate-independent pathway: Isopentenyl monophosphate kinase catalyzes the terminal enzymatic step
43. Cell walls of mycobacteria and related organisms; chemistry and immunostimulant properties
44. Mycobacterium tuberculosis cell envelope
45. Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis
46. Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
47. Determination of the pathway for rhamnose biosynthesis in mycobacteria: Cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase
48. Drug targeting Mycobacterium tuberculosis cell wall synthesis: Genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose
49. Comparison of the UDP-N-acetylmuramate:L-alanine ligase enzymes from Mycobacterium tuberculosis and Mycobacterium leprae
50. Arabinogalactan in mycobacteria: Structure, biosynthesis, and genetics
51. Structure, function and biogenesis of the cell envelope of mycobacteria in relation to bacterial physiology, pathogenesis and drug resistance; some thoughts and possibilities arising from recent structural information
52. Chemistry of the mycobacterial cell wall
53. Evidence for the nature of the link between the arabinogalactan and peptidoglycan of mycobacterial cell walls
54. Demonstration that the galactosyl and arabinosyl residues in the cell- wall arabinogalactan of Mycobacterium leprae and Mycobacterium tuberculosis are furanoid
55. Enzymatic evidence for the presence of a critical terminal hexa- arabinoside in the cell walls of Mycobacterium tuberculosis
56. Biosynthesis of the linkage region of the mycobacterial cell wall
57. Biosynthesis of the galactan component of the mycobacterial cell wall
58. Galactofuranose biosynthesis in Escherichia coli K-12: Identification and cloning of UDP-galactopyranose mutase
59. Distribution of mevalonate and glyceraldehyde 3-phosphate/pyruvate routes for isoprenoid biosynthesis in some gram-negative bacteria and mycobacteria
60. Incorporation of [2, 3-C-13(2)]- and [2, 4-C-13(2)]-D-1-deoxyxylulose into ubiquinone of Escherichia coli via the mevalonate-independent pathway for isoprenoid biosynthesis
61. The mechanism of the condensation reactions of cholesterol biosynthesis. Fourth Morton lecture
62. Distribution, metabolism and function of dolichol and polyprenols
63. Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli
64. Cytidine 5′-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4- diphosphocytidyl-2-C-methylerythritol
65. Isoprenoid biosynthesis in bacteria: A novel pathway for the early steps leading to isopentenyl diphosphate
66. Biosynthetic origin of mycobacterial cell wall arabinosyl residues
67. Polyprenylphosphate-pentoses in mycobacteria are synthesized from 5- phosphoribose pyrophosphate
68. Peptidoglycan types of bacterial cell walls and their taxonomic implications
69. 50) chain isoprenyl diphosphate synthase in Mycobacterium tuberculosis
70. Purification, enzymatic characterization, and inhibition of the Z-farnesyl diphosphate synthase from Mycobacterium tuberculosis
71. Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol
72. Conversion of dTDP-4-keto-6-deoxyglucose to free dTDP-4-keto-rhamnose by the rmIC gene products of Escherichia coli and Mycobacterium tuberculosis
73. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis
74. Enzymatic synthesis of mannosyl-1-phosphoryl-decaprenol by a cell-free system of Mycobacterium tuberculosis
75. Characterization of the alkali-stable mannophospholipids of Mycobacterium smegmatis
76. A defect in cell wall recycling triggers autolysis during the stationary growth phase of Escherichia coli
77. Murein synthesis
78. Formation of the glycan chains in the synthesis of bacterial peptidoglycan
79. Biosynthetic origin of mycobacterial cell wall galactofuranosyl residues
80. Occurrence of D-alanyl-(D)-meso-diaminopimelic acid and meso-diaminopimelyl-meso-diaminopimelic acid interpeptide linkages in the peptidoglycan of mycobacteria
81. Isolation and characterization of the major form of polyprenyl-phospho-mannose from Mycobacterium smegmatis
82. Recognition of the lipid intermediate for arabinogalactan/arabinomannan biosynthesis and its relation to the mode of action of ethambutol on mycobacteria
83. Early steps of isoprenoid biosynthesis in Escherichia coli