The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate

Journal of Molecular Biology

Volumn 355, Issue 4, 2006, Pages 784-797

  Lee, Clare E ^a   Goodfellow, Catherine ^a   Javid Majd, Farah ^b   Baker, Edward N ^a   Shaun Lott, J ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Anthranilate phosphoribosyltransferase; Crystal structure; Substrate binding; Tryptophan biosynthesis; Tuberculosis

Indexed keywords

ANTHRANILIC ACID; MAGNESIUM ION; PHOSPHORIBOSYL PYROPHOSPHATE; PHOSPHORIBOSYLTRANSFERASE;

ARTICLE; BACTERIAL COLONIZATION; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPUTER MODEL; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME SUBSTRATE; HYDROGEN BOND; MOLECULAR INTERACTION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM TUBERCULOSIS;

EID: 29144495844     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.11.016     Document Type: Article

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