Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans and catalytic reaction mechanism

Journal of Biological Chemistry

Volumn 282, Issue 23, 2007, Pages 17221-17230

  Maruyama, Daisuke ^a   Nishitani, Yuichi ^a   Nonaka, Tsuyoshi ^a   Kita, Akiko ^a   Fukami, Takaaki A ^b   Mio, Toshiyuki ^b   Yamada Okabe, Hisafumi ^b   Yamada Okabe, Toshiko ^c   Miki, Kunio ^a,d  

^a KYOTO UNIVERSITY   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

^d Harima Institute ^*  (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTIC PROTEINS; GLYCOSYLPHOSPHOINOSITOL ANCHORS; URIDINE;

AMINES; BACTERIA; BIOSYNTHESIS; CELL MEMBRANES; CRYSTAL STRUCTURE; ESTERIFICATION; GLYCOSYLATION; LIGANDS;

ENZYME ACTIVITY;

ENZYME; GLUCOSAMINE DERIVATIVE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHO N ACETYLGLUCOSAMINE; URIDINE DIPHOSPHO N ACETYLGLUCOSAMINE PYROPHOSPHORYLASE; URIDINE TRIPHOSPHATE; NUCLEOTIDYLTRANSFERASE; UDPACETYLGLUCOSAMINE PYROPHOSPHORYLASE;

ARTICLE; CANDIDA ALBICANS; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; PRIORITY JOURNAL; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); CANDIDA ALBICANS; EUKARYOTA; PROKARYOTA;

AMINO ACID SEQUENCE; BINDING SITES; CANDIDA ALBICANS; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDYLTRANSFERASES; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 34447126347     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611873200     Document Type: Article

References (36)

1. Holtje, J. V., and Schwartz, U. (1985) in Molecular Cytology of Escherichia coli (Nanninga, N., ed), pp. 77-119, Academic Press, Inc., New York
2. Park, J. T. (1987) in Escherichia coli and Salmonella typhimurinum: Cellular and Molecular Biology (Neidhardt, F. C., Ingraham, J. L., Low, K. H., Magasanik, B., Schaechter, M., and Umbarger, H. E., eds) Vol. 1, pp. 663-671, American Society for Microbiology, Washington, D. C.
3. Raetz, C. R. H. (1987) in Escherichia coli and Salmonella typhimurinum: Cellular and Molecular Biology (Neidhardt, F. C., Ingraham, J. L., Low, K. H., Magasanik, B., Schaechter, M., and Umbarger, H. E., eds) Vol. 1, pp. 498-503, American Society for Microbiology, Washington, D. C.
4. Cabib, E., Roberts, R., and Bowers, B. (1982) Annu. Rev. Biochem. 51, 763-793
5. Herscovics, A., and Orlean, P. (1993) FASEB J. 7, 540-550
6. Mio, T., Yabe, T., Arisawa, M., and Yamada-Okabe, H. (1998) J. Biol. Chem. 273, 14392-14397
7. Mengin-Lecreulx, D., and van Heijenoort, J. (1994) J. Bacteriol. 176, 5788-5795
8. Mio, T., Yamada-Okabe, T., Arisawa, M., and Yamada-Okabe, H. (1999) J. Biol. Chem. 274, 424-429
9. Mio, T., Yamada-Okabe, T., Arisawa, M., and Yamada-Okabe, H. (2000) Biochim. Biophys. Acta 1492, 369-376
10. Sheu, K. F., and Frey, P. A. (1978) J. Biol. Chem. 253, 3378-3380
11. Kostrewa, D., D'Arcy, A., Takacs, B., and Kamber, M. (2001) J. Mol. Biol. 305, 279-289
12. Bulik, D. A., Lindmark, D. G., and Jarroll, E. L. (1998) Mol. Biochem. Parasitol. 95, 135-139
13. Wang-Gillam, A., Pastuszak, I., Stewart, M., Drake, R. R., and Elbein, A. D. (2000) J. Biol. Chem. 275, 1433-1438
14. Brown, K., Pompeo, F., Dixon, S., Mengin-Lecreulx, D., Cambillau, C., and Bourne, Y. (1999) EMBO J. 18, 4096-4107
15. Olsen, L. R., and Roderick, S. L. (2001) Biochemistry 40, 1913-1921
16. Sulzenbacher, G., Gal, L., Peneff, C., Fassy, F., and Bourne, Y. (2001) J. Biol. Chem. 276, 11844-11851
17. Peneff, C., Ferrari, P., Charrier, V., Taburet, Y., Monnier, C., Zamboni, V., Winter, J., Harnois, M., Fassy, F., and Bourne, Y. (2001) EMBO J. 20, 6191-6202
18. Charnock, S. J., and Davies, G. J. (1999) Biochemistry 38, 6380-6385
19. Unligil, U. M., Zhou, S., Yuwaraj, S., Sarkar, M., Schachter, H., and Rini, J. M. (2000) EMBO J. 19, 5269-5280
20. Unligil, U. M., and Rini, J. M. (2000) Curr. Opin. Struct. Biol. 10, 510-517
21. Rogers, T. J., and Balish, E. (1980) Microbiol. Rev. 44, 660-682
22. Maruyama, D., Nishitani, Y., Nonaka, T., Kita, A., Fukami, T. A., Mio, T., Yamada-Okabe, H., Yamada-Okabe, T., and Miki, K. (2006) Acta Crystallograph Sect. F Struct. Biol. Crystallogr. Commun. 62, 1206-1208
23. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
24. Navaza, J. (1994) Acta Crystallogr. Sect. A Found. Crystallogr. 50, 157-163
25. Collaborative Computational Project Number 4 (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 760-763
26. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. Sect. A Found. Crystallogr. 47, 110-119
27. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. Sect. D Biol. Crystallogr. 54, 905-921
28. Laskowski, R. A., W., M. M., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
29. Kabsch, W. (1976) Acta Crystallogr. Sect. A Found. Crystallogr. 32, 922-923
30. Kleywegt, G. J. (1996) Acta Crystallogr. Sect. D Biol. Crystallogr. 52, 842-857
31. DeLano, W. L. (2002) The Pymol Molecular Graphics System, DeLano Scientific, San Carlos, CA
32. Rossmann, M. G., Lijas, A., Branden, C.-I., and Bansazak, L. J. (1975) in The Enxymes (Boyer, P. D., ed) Vol. 11, pp. 61-102, Academic Press, New York
33. Blankenfeldt, W., Asuncion, M., Lam, J. S., and Naismith, J. H. (2000) EMBO J. 19, 6652-6663
34. Thompson, J. D., Higgins, D. G., and Gibson, T. J. (1994) Nucleic Acids Res. 22, 4673-4680
35. Kabsch, W., and Sander, C. (1983) Biopolymers 22, 2577-2637
36. Gouet, P., Courcelle, E., Stuart, D. I., and Metoz, F. (1999) Bioinformatics 15, 305-308