Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: Biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Lucarelli, Anna P ^a   Buroni, Silvia ^a   Pasca, Maria R ^a   Rizzi, Menico ^b   Cavagnino, Andrea ^b   Valentini, Giovanna ^a   Riccardi, Giovanna ^a   Chiarelli, Laurent R ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CALCIUM ION; COPPER ION; GUANOSINE DIPHOSPHATE; MAGNESIUM ION; MANGANESE; RECOMBINANT ENZYME; RIBOSE 5 PHOSPHATE; RIBOSEPHOSPHATE PYROPHOSPHOKINASE; SULFATE; BACTERIAL PROTEIN; DIVALENT CATION; MAGNESIUM; RECOMBINANT PROTEIN;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME CHEMISTRY; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; MOLECULAR DYNAMICS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; BINDING SITE; BIOCATALYSIS; CELL WALL; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; DRUG EFFECT; ENZYME STABILITY; ENZYMOLOGY; GENETICS; HEAT; KINETICS; METABOLISM; PROTEIN DENATURATION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

MYCOBACTERIUM TUBERCULOSIS;

BACTERIAL PROTEINS; BINDING SITES; BIOCATALYSIS; CATIONS, DIVALENT; CELL WALL; CIRCULAR DICHROISM; ENZYME ACTIVATION; ENZYME STABILITY; HOT TEMPERATURE; KINETICS; MAGNESIUM; MANGANESE; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PROTEIN DENATURATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RIBOSE-PHOSPHATE PYROPHOSPHOKINASE; SUBSTRATE SPECIFICITY;

EID: 78649731694     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015494     Document Type: Article

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