Conformational antagonism between opposing active sites in a bifunctional RelA/SpoT homolog modulates (p)ppGpp metabolism during the stringent response

Cell

Volumn 117, Issue 1, 2004, Pages 57-68

  Hogg, Tanis ^a,b   Mechold, Undine ^c,d,f   Malke, Horst ^c,e   Cashel, Mike ^d   Hilgenfeld, Rolf ^a,b  

^a UNIVERSITY OF LÜBECK   (Germany)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^e UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^f INSTITUT ANDRÉ LWOFF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE DIPHOSPHATE; HYDROLASE; NUCLEOTIDYLTRANSFERASE; PHOSPHODIESTERASE; SPO11 PROTEIN; SYNTHETASE; TRANSCRIPTION FACTOR REL;

ARTICLE; CATALYSIS; CONFORMATION; CRYSTAL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; HYDROLYSIS; MUTAGENESIS; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; PROTEIN FAMILY; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; STREPTOCOCCUS DYSGALACTIAE; STREPTOCOCCUS DYSGALACTIAE EQUISIMILIS; SYNTHESIS;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STREPTOCOCCUS; STREPTOCOCCUS DYSGALACTIAE; STREPTOCOCCUS DYSGALACTIAE SUBSP. EQUISIMILIS;

EID: 1842766260     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(04)00260-0     Document Type: Article

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