Crystal structure of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, a potential target for the development of novel antimicrobial agents

Structure

Volumn 7, Issue 5, 1999, Pages 489-496

  Bing, Xiao ^a   Genbin, Shi ^b   Xin, Chen ^a   Honggao, Yan ^b   Xinhua, Ji ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Michigan State University   (United States)

Author keywords

Antimicrobial agent; Drug design; HPPK; Protein fold; Pyrophosphoryl transfer

Indexed keywords

6 HYDROXYMETHYL 7,8 DIHYDROPTERIN PYROPHOSPHOKINASE; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA;

EID: 0033135167     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(99)80065-3     Document Type: Article

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