Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the aprt catalytic mechanism

Journal of Biomolecular Structure and Dynamics

Volumn 25, Issue 6, 2008, Pages 589-597

  Silva, Carlos H T P ^a   Silva, Marcio ^a   Iulek, Jorge ^b   Thiemann, Otavio H ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ADENINE PHOSPHORIBOSYLTRANSFERASE; ADENOSINE PHOSPHATE;

ARTICLE; ATOM; CATALYSIS; COMPARATIVE STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBUNIT; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

KINETOPLASTIDA; PROTOZOA;

EID: 43749109227     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2008.10507205     Document Type: Article

References (25)

1. Silva, M., Silva, C. H.T. P., Iulek, J., and Thiemann, O. H., 2004. Biochemistry, 43:7663–7671.
2. Silva, M., Silva, C. H.T. P., Iulek, J., and Thiemann, O. H., 2003. Biochim Biophys Acta, 1969:31–39.
3. Vos, S., Parry, R. J., Burns, M. R., de Jersey, J., and Martin, J. L., 1998. J Mol Biol, 282:875–889.
4. Shi, W., Sarver, A. E., Wang, C. C., Tanaka, K. S. E., Almo, S. C., and Schramm, V. L., 2002. J Biol Chem, 277:39981–39988.
5. Shi, W., Li, C. M., Tyler, P. C., Furneaux, R. H., Grubmeyer, C., Schramm, V. L., and Almo, S. C., 1999. Nature Struct Biol, 6:588–593.
6. Henriksen, A., Aghajari, N., Jensen, K. F., and Galhede, M., 1996. Biochemistry, 35:3803–3809.
7. Greenwood, M. C., Dillon, M. J., Simmonds, H. A., Barratt, T. M., Pincott, J. R., and Metreweli, C., 1982. Eur J Pediatr, 138:346–349.
8. Focia, P. J., Craig, S. P., and Eakin, A. E. A., 1998. Biochemistry, 37:17120–17127.
9. Williamsashman, H. G., Seidenfeld, J., and Galletti, P., 1982. Biochem Pharmacol, 31:277–278.
10. Kamatani, N., Hakoda, M., Otsuka, S., Yoshikawa, H., and Kashiwazaki, S., 1992. J Clin Investig, 90:130–136.
11. Stone, T. W., and Simmonds, H. A., 1991. Purines:Basic and Clinical Aspects. Edited by:Kluwer, Ed., London:Academic Press.
12. Wyngaarden, J. B., and Dunn, J. T., 1957. Arch Biochem Biophys, 70:150–156.
13. de Vries, A., and Sperling, O., 1977. Ciba Found Symp, 48:179–206.
14. del Sol, F. G., Ramon-Maiques, S., Santos, C. F., Grangeiro, T. B., Nagano, C. S., Farias, C. M.S. A., Cavada, B. S., and Calvete, J. J., 2002. Acta Cryst, D58:167–169.
15. Chang, G., and Lewis, M., 1994. Acta Cryst, D50:667–674.
16. Navaza, J., 1994. Acta Cryst, A50:157–163.
17. Brunger, A. T., Adams, P. D., Clore, G. M., Delano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, N., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L., 1998. Acta Crystallogr, D54:905–921.
18. Murshudov, G. N., Vagin, A. A., and Dodson, E. J., 1997. Acta Crystallogr, D53:240–255.
19. McRee, D. E., 1992. J Mol Graphics, 10:44–46.
20. Perrakis, A., Morris, R. J. H., and Lamzin, V. S., 1999. Nat Struct Biol, 6:458–463.
21. de Lano, W., 2005. The PyMOL Molecular Graphics System, De Lano Scientific LLC, San Carlos, CA, USA. http://www.pymol.org.
22. Nayal, M., and Di Cera, E., 1996. J Mol Biol, 256:228–234.
23. Kleywegt, G. J., 1992. Uppsala, Sweden:Uppsala University. Unpublished program, -2004
24. Shi, W., Tanaka, K. S. E., Crother, T. R., Taylor, M. W., Almo, S. C., and Schramm, V. L., 2001. Biochemistry, 40:10800–10809.
25. McRee, D. E., 1999. J Struct Biol, 125:156–165.