Crystal Structure of a Type II Quinolic Acid Phosphoribosyltransferase (TM1645) from Thermotoga maritima at 2.50 Å Resolution

Proteins: Structure, Function and Genetics

Volumn 55, Issue 3, 2004, Pages 768-771

  Schwarzenbacher, Robert ^a,b   Jaroszewski, Lukasz ^a,b   Von Delft, Frank ^a,c   Abdubek, Polat ^a,d   Ambing, Eileen ^a,d   Biorac, Tanja ^a,d   Brinen, Linda S ^a,e   Canaves, Jaume M ^a,b   Cambell, Jamison ^a,d   Chiu, Hsiu Ju ^a,e   Dai, Xiaoping ^a,c   Deaeon, Ashley M ^a,e   DiDonato, Mike ^a,e   Elsliger, Mare André ^a,c   Eshagi, Said ^a,d   Floyd, Ross ^a,e   Godzik, Adam ^a,b   Grittini, Carina ^a,c   Grzechnik, Slawomir K ^a,b   Hampton, Eric ^a,d   Karlak, Cathy ^a,d   Klock, Heath E ^a,d   Koesema, Eric ^a,d   Kovarik, John S ^a,e   Kreusch, Andreas ^a,d   Kuhn, Peter ^a,e   Lesley, Scott A ^a,d   Levin, Inna ^a,e   McMullan, Daniel ^a,d   McPhillips, Timothy M ^a,e   Miller, Mitchell D ^a,e   Morse, Andrew ^a,b   Moy, Kin ^a,c   Ouyang, Jie ^a,b   Page, Rebecca ^a,c   Quijano, Kevin ^a,d   Robb, Alyssa ^a,d   Spraggon, Glen ^a,d   Stevens, Raymond C ^a,c   Van Den Bedem, Henry ^a,e   Velasquez, Jeff ^a,c   Vincent, Juli ^a,d   Wang, Xianhong ^a,b   West, Bill ^a,b   Wolf, Guenter ^a,e   Xu, Qingping ^a,e   Hodgson, Keith O ^a,e   Wooley, John ^a,b,f   Wilson, Ian A ^a,c   more..

^a Joint Center for Structural Genomics   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^e SLAC NATIONAL ACCELERATOR LABORATORY   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TM1645; QUINOLIC ACID PHOSPHORIBOSYLTRANSFERASE TYPE II; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; CRYSTAL STRUCTURE; CRYSTALLIZATION; PRIORITY JOURNAL; PROTEIN DATABASE; PROTEIN STRUCTURE; THERMOTOGA MARITIMA; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PENTOSYLTRANSFERASES; THERMOTOGA MARITIMA;

BACTERIA (MICROORGANISMS); THERMOTOGA; THERMOTOGA MARITIMA;

EID: 2442472266     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.20029     Document Type: Article

References (18)

1. Foster JW, Moat AG. Nicotinamide adenine dinucleotide biosynthesis and pyridine nucleotide cycle metabolism in microbial systems. Microbiol Rev 1980;44:83-105.
2. Cao H, Pietrak BL, Grubmeyer C. Quinolinate phosphoribosyltransferase: kinetic mechanism for a type II PRTase. Biochemistry 2002;41:3520-3528.
3. Rajavel M, Lalo D, Gross JW, Grubmeyer C. Conversion of a cosubstrate to an inhibitor: phosphorylation mutants of nicotinic acid phosphoribosyltransferase. Biochemistry 1998;37:4181-4188.
4. Eads JC, Ozturk D, Wexler TB, Grubmeyer C, Sacchettini JC. A new function for a common fold: the crystal structure of quinolinic acid phosphoribosyltransferase. Structure 1997;5:47-58.
5. Sharma V, Grubmeyer C, Sacchettini JC. Crystal structure of quinolinic acid phosphoribosyltransferase from Mycobacterium tuberculosis: a potential TB drug target. Structure 1998;6:1587-1599.
6. Lesley SA, Kuhn P, Godzik A, Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Wooley J, Taylor SS, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci USA 2002;99:11664-11669.
7. Laskowski RA, MacArthur MW, Moss DS, Thornton JM. PRO-CHECK a program to check the stereochemical quality of protein structures. J Appl Crystallogr 1993;26:283-291.
8. Murzin AG, Brenner SE, Hubbard T, Chothia C. SCOP: a structural classification of proteins database for the investigation of sequences and structures. J Mol Biol 1995;247:536-540.
9. Holm L, Sander C. Dali: a network tool for protein structure comparison. Trends Biochem Sci 1995;20:478-480.
10. Jaroszewski L, Li W, Godzik A. In search for more accurate alignments in the twilight zone. Protein Sci 2002;11:1702-1713.
11. Santarsiero BD, Yegian DT, Lee CC, Spraggon G, Gu J, Scheibe D, Uber DC, Cornell EW, Nordmeyer RA, Kolbe WF, Jin J, Jones AL, Jaklevic JM, Schultz PG, Stevens RC. An approach to rapid protein crystallization using nanodroplets. J Appl Crystallogr 2002;35:278-281.
12. McPhillips TM, McPhillips SE, Chiu HJ, Cohen AE, Deacon AM, Ellis PJ, Garman E, Gonzalez A, Sauter NK, Phizackerley RP, Soltis SM, Kuhn P. Blu-Ice and the Distributed Control System: software for data acquisition and instrument control at macromolecular crystallography beamlines. J Synchrotron Radiat 2002;9: 401-406.
13. Leslie AGW. Recent changes to the MOSFLM package for processing film and image plate data. Joint CCP4 + ESF-EAMCB Newsletter on Protein Crystallography 1992;26.
14. Collaborative Computational Project Number 4. The CCP4 Suite: Programs for Protein Crystallography. Acta Crystallogr 1994;D50: 760-763.
15. Vriend G. J. WHATIF: a molecular modeling and drug design program. Mol Graph 1990;8:52-56.
16. Jones TA, Zou J-Y, Cowan SW, Kjeldaard M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr 1991;D47:110-119.
17. McRee DE. XtalView/Xfit - a versatile program for manipulating atomic coordinates and electron density. J Struct Biol 1999;125: 156-165.
18. Tickle IJ, Laskowski RA, Moss DS. Error estimates of protein structure coordinates and deviations from standard geometry by full-matrix refinement of gammaB- and betaB2-crystallin. Acta Crystallogr 1998;D54:243-252.