-
1
-
-
37049031842
-
-
Chu, E., and Takimoto, C. H. (1993) in Cancer: Principles & Practice of Oncology (De Vita, V. T., Jr., Hellman, S., and Rosenberg, S. A., Eds.) 4th ed., I, pp 362-365, Lippincott, Philadelphia, PA.
-
Chu, E., and Takimoto, C. H. (1993) in Cancer: Principles & Practice of Oncology (De Vita, V. T., Jr., Hellman, S., and Rosenberg, S. A., Eds.) 4th ed., Vol. I, pp 362-365, Lippincott, Philadelphia, PA.
-
-
-
-
2
-
-
0343352274
-
-
Scriver, C. R, Beaudet, A. L, Sly, W. S, and Valle, D, Eds, 6th ed, pp, McGraw-Hill, New York
-
Suttle, J. P., Becroft, D. M. O., and Webster, D. R. (1989) in The Metabolic Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., Eds.) 6th ed., pp 1095-1126, McGraw-Hill, New York.
-
(1989)
The Metabolic Basis of Inherited Disease
, pp. 1095-1126
-
-
Suttle, J.P.1
Becroft, D.M.O.2
Webster, D.R.3
-
3
-
-
0001814559
-
-
Scriver, C. R, Beaudet, A. L, Sly, W. S, and Valle, D, Eds, 6th ed, pp, McGraw-Hill, New York
-
Simmonds, H. A., Sahota, A. S., and Van Acker, K. J. (1989) in The Metabolic Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., Eds.) 6th ed., pp 1029-1044, McGraw-Hill, New York.
-
(1989)
The Metabolic Basis of Inherited Disease
, pp. 1029-1044
-
-
Simmonds, H.A.1
Sahota, A.S.2
Van Acker, K.J.3
-
4
-
-
0002980254
-
-
Scriver, C. R, Beaudet, A. L, Sly, W. S, and Valle, D, Eds, 6th ed, pp, McGraw-Hill, New York
-
Stout, J. T., and Caskey, C. T. (1989) in The Metabolic Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., Eds.) 6th ed., pp 1007-1028, McGraw-Hill, New York.
-
(1989)
The Metabolic Basis of Inherited Disease
, pp. 1007-1028
-
-
Stout, J.T.1
Caskey, C.T.2
-
5
-
-
0028836011
-
Hypoxanthine-guanine phosphoribosyltransferase as a therapeutic target in protozoal infections
-
Ullman, B., and Cater, D. (1995) Hypoxanthine-guanine phosphoribosyltransferase as a therapeutic target in protozoal infections, Infect. Agents Dis. 4, 29-40.
-
(1995)
Infect. Agents Dis
, vol.4
, pp. 29-40
-
-
Ullman, B.1
Cater, D.2
-
6
-
-
0030937673
-
Inactivation of Tritrichomonas foetus and Schistosoma mansoni purine phosphoribosyltransferases by arginine-specific reagents
-
Kanaani, J., Maltby, D., Somoza, J. R., and Wang, C. C. (1997) Inactivation of Tritrichomonas foetus and Schistosoma mansoni purine phosphoribosyltransferases by arginine-specific reagents, Eur. J. Biochem. 244, 810-817.
-
(1997)
Eur. J. Biochem
, vol.244
, pp. 810-817
-
-
Kanaani, J.1
Maltby, D.2
Somoza, J.R.3
Wang, C.C.4
-
7
-
-
0017904809
-
3H substrate kinetic isotope effects for some phosphoribosyltransferases
-
3H substrate kinetic isotope effects for some phosphoribosyltransferases, J. Biol. Chem. 253, 2963-2971.
-
(1978)
J. Biol. Chem
, vol.253
, pp. 2963-2971
-
-
Goitein, R.K.1
Chelsky, D.2
Parsons, S.3
-
8
-
-
0018800824
-
Studies of the kinetic mechanism of orotate phosphoribosyltransferase from yeast
-
Victor, J., Greenberg, L. B., and Sloan, D. L. (1979) Studies of the kinetic mechanism of orotate phosphoribosyltransferase from yeast, J. Biol. Chem. 254, 2647-2655.
-
(1979)
J. Biol. Chem
, vol.254
, pp. 2647-2655
-
-
Victor, J.1
Greenberg, L.B.2
Sloan, D.L.3
-
9
-
-
0032863613
-
Cloning, overproduction, and purification of native and mutant recombinant yeast orotate phosphoribosyltransferase and the demonstration from magnetization inversion transfer that a proposed oxocarbocation does not have a kinetic lifetime
-
Witte, J. F., Tsou, R., and McClard, R. W. (1999) Cloning, overproduction, and purification of native and mutant recombinant yeast orotate phosphoribosyltransferase and the demonstration from magnetization inversion transfer that a proposed oxocarbocation does not have a kinetic lifetime, Arch. Biochem. Biophys. 361, 106-112.
-
(1999)
Arch. Biochem. Biophys
, vol.361
, pp. 106-112
-
-
Witte, J.F.1
Tsou, R.2
McClard, R.W.3
-
10
-
-
33645963745
-
Half-of-sites binding of orotidine 5′-phosphate and α-D-5- phosphorylribose 1-diphosphate to orotate phosphoribosyltransferase from Saccharomyces cerevisiae supports a novel variant of the Theorell-Chance mechanism with alternating site catalysis
-
McClard, R. W., Holets, E. A., MacKinnon, A. L., and Witte, J. (2006) Half-of-sites binding of orotidine 5′-phosphate and α-D-5- phosphorylribose 1-diphosphate to orotate phosphoribosyltransferase from Saccharomyces cerevisiae supports a novel variant of the Theorell-Chance mechanism with alternating site catalysis, Biochemistry 45, 5330-5342.
-
(2006)
Biochemistry
, vol.45
, pp. 5330-5342
-
-
McClard, R.W.1
Holets, E.A.2
MacKinnon, A.L.3
Witte, J.4
-
11
-
-
0025244323
-
Kinetic mechanism of orotate phosphoribosyltransferase from Salmonella typhimurium
-
Bhatia, M. B., Vinitsky, A., and Grubmeyer, C. (1990) Kinetic mechanism of orotate phosphoribosyltransferase from Salmonella typhimurium, Biochemistry 29, 10480-10487.
-
(1990)
Biochemistry
, vol.29
, pp. 10480-10487
-
-
Bhatia, M.B.1
Vinitsky, A.2
Grubmeyer, C.3
-
12
-
-
0028281205
-
Crystal structure of orotate phosphoribosyltransferase
-
Scapin, G., Grubmeyer, C., and Sacchettini, J. C. (1994) Crystal structure of orotate phosphoribosyltransferase, Biochemistry 33, 1287-1294.
-
(1994)
Biochemistry
, vol.33
, pp. 1287-1294
-
-
Scapin, G.1
Grubmeyer, C.2
Sacchettini, J.C.3
-
13
-
-
0029143903
-
The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and α-D-5-phosphoribosyl-1-pyrophosphate
-
Scapin, G., Ozturk, D. H., Grubmeyer, C., and Sacchettini, J. C. (1995) The crystal structure of the orotate phosphoribosyltransferase complexed with orotate and α-D-5-phosphoribosyl-1-pyrophosphate, Biochemistry 34, 10744-10754.
-
(1995)
Biochemistry
, vol.34
, pp. 10744-10754
-
-
Scapin, G.1
Ozturk, D.H.2
Grubmeyer, C.3
Sacchettini, J.C.4
-
14
-
-
0033524485
-
Motional dynamics of the catalytic loop in OMP synthase
-
Wang, G. P., Cahill, S. M., Liu, X., Girvin, M. E., and Grubmeyer, C. (1999) Motional dynamics of the catalytic loop in OMP synthase, Biochemistry 38, 284-295.
-
(1999)
Biochemistry
, vol.38
, pp. 284-295
-
-
Wang, G.P.1
Cahill, S.M.2
Liu, X.3
Girvin, M.E.4
Grubmeyer, C.5
-
15
-
-
0033024577
-
Forming and inhibiting PRT active sites
-
Smith, J. L. (1999) Forming and inhibiting PRT active sites, Nat. Struct. Biol. 6, 502-504.
-
(1999)
Nat. Struct. Biol
, vol.6
, pp. 502-504
-
-
Smith, J.L.1
-
16
-
-
0342894815
-
Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site
-
Krahn, J. M., Kim, J. H., Burns, M. R., Parry, R. J., Zalkin, H., and Smith, J. L. (1997) Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site, Biochemistry 36, 11061-11068.
-
(1997)
Biochemistry
, vol.36
, pp. 11061-11068
-
-
Krahn, J.M.1
Kim, J.H.2
Burns, M.R.3
Parry, R.J.4
Zalkin, H.5
Smith, J.L.6
-
17
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem. 72, 248-256.
-
(1976)
Anal. Biochem
, vol.72
, pp. 248-256
-
-
Bradford, M.M.1
-
18
-
-
0033213239
-
The finer things in X-ray diffraction data collection
-
Pflugrath, J. W. (1999) The finer things in X-ray diffraction data collection, Acta Crystallogr. D55, 1718-1725.
-
(1999)
Acta Crystallogr
, vol.D55
, pp. 1718-1725
-
-
Pflugrath, J.W.1
-
19
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z., and Minor, W. (1997) Processing of X-ray diffraction data collected in oscillation mode, Methods Enzymol. 276, 307-326.
-
(1997)
Methods Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
20
-
-
84920325457
-
AMoRe: An automated package for molecular replacement
-
Navaza, J. (1994) AMoRe: an automated package for molecular replacement, Acta Crystallogr. A50, 157-163.
-
(1994)
Acta Crystallogr
, vol.A50
, pp. 157-163
-
-
Navaza, J.1
-
21
-
-
0000560808
-
MOLREP: An automated program for molecular replacement
-
Vagin, A., and Teplyakov, A. (1997) MOLREP: an automated program for molecular replacement, J. Appl. Crystallogr. 30, 1022-1025.
-
(1997)
J. Appl. Crystallogr
, vol.30
, pp. 1022-1025
-
-
Vagin, A.1
Teplyakov, A.2
-
22
-
-
0028103275
-
-
Collaborative computational project, Number 4 (1994) The CCP4 suite: Programs for protein crystallography, Acta Crystallogr. D50, 760-763.
-
Collaborative computational project, Number 4 (1994) The CCP4 suite: Programs for protein crystallography, Acta Crystallogr. D50, 760-763.
-
-
-
-
23
-
-
3543012707
-
Crystallography and NMR System: A new software system for macromolecular structure determination
-
Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J.-S., Kuszewski, J., Nilges, N., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Crystallography and NMR System: A new software system for macromolecular structure determination, Acta Crystallogr. D54, 905-921.
-
(1998)
Acta Crystallogr
, vol.D54
, pp. 905-921
-
-
Brünger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.-S.7
Kuszewski, J.8
Nilges, N.9
Pannu, N.S.10
Read, R.J.11
Rice, L.M.12
Simonson, T.13
Warren, G.L.14
-
24
-
-
84889120137
-
Improved methods for building protein models in electron density maps and the location of errors in these models
-
Jones, T. A., Zhou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1998) Improved methods for building protein models in electron density maps and the location of errors in these models, Acta Crystallogr. A47, 110-119.
-
(1998)
Acta Crystallogr
, vol.A47
, pp. 110-119
-
-
Jones, T.A.1
Zhou, J.Y.2
Cowan, S.W.3
Kjeldgaard, M.4
-
25
-
-
13244281317
-
Coot: Model-building tools for molecular graphics
-
Emsley, P., and Cowtan, K. (2004) Coot: model-building tools for molecular graphics, Acta Crystallogr. D60, 2126-2132.
-
(2004)
Acta Crystallogr
, vol.D60
, pp. 2126-2132
-
-
Emsley, P.1
Cowtan, K.2
-
26
-
-
0032215320
-
Databases in protein crystallography
-
Kleywegt, G. J., and Jones, T. A. (1998) Databases in protein crystallography, Acta Crystallogr. D54, 1119-1131.
-
(1998)
Acta Crystallogr
, vol.D54
, pp. 1119-1131
-
-
Kleywegt, G.J.1
Jones, T.A.2
-
27
-
-
0032006209
-
Systematic analysis of domain motions in proteins from conformational change: New results on citrate synthase and T4 lysozyme
-
Hayward, S., and Berendsen, H. J. C. (1998) Systematic analysis of domain motions in proteins from conformational change: New results on citrate synthase and T4 lysozyme. Proteins: Struct., Funct., Genet. 30, 144-154.
-
(1998)
Proteins: Struct., Funct., Genet
, vol.30
, pp. 144-154
-
-
Hayward, S.1
Berendsen, H.J.C.2
-
28
-
-
84893482610
-
A solution for the best rotation to relate two sets of vectors
-
Kabsch, W. (1976) A solution for the best rotation to relate two sets of vectors, Acta Crystallogr. A32, 922-923.
-
(1976)
Acta Crystallogr
, vol.A32
, pp. 922-923
-
-
Kabsch, W.1
-
29
-
-
37049017034
-
-
on World Wide Web
-
DeLano, W. L. (2002) The PyMOL Molecular Graphics System on World Wide Web, http://www.pymol.org.
-
(2002)
-
-
DeLano, W.L.1
-
30
-
-
0031473847
-
SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling
-
Guex, N., and Peitsch, M. C. (1997) SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling, Electrophoresis 18, 2714-2733.
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2733
-
-
Guex, N.1
Peitsch, M.C.2
-
31
-
-
37049038367
-
-
Cason, C. J, 1999 POV-Ray for Windows, version 3.1
-
Cason, C. J. (1999) POV-Ray for Windows, version 3.1, http://www.povray.org/.
-
-
-
-
32
-
-
0024556721
-
Structure and expression of the URA5 gene of Saccharomyces cerevisiae
-
De Montigny, J., Belarbi, A., Hubert, J. C., and LaCroute, F. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae, Mol. Gen. Genet. 215, 455-462.
-
(1989)
Mol. Gen. Genet
, vol.215
, pp. 455-462
-
-
De Montigny, J.1
Belarbi, A.2
Hubert, J.C.3
LaCroute, F.4
-
33
-
-
0004204457
-
-
Garland Publishing, Inc, New York
-
Branden, C., and Tooze, J. (1991) Introduction to protein structure, Garland Publishing, Inc., New York.
-
(1991)
Introduction to protein structure
-
-
Branden, C.1
Tooze, J.2
-
34
-
-
0027256582
-
The Role of Divalent Magnesium in Activating the Reaction Catalyzed by Orotate Phosphoribosyltransferase
-
Bhatia, M. B., and Grubmeyer, C. (1993) The Role of Divalent Magnesium in Activating the Reaction Catalyzed by Orotate Phosphoribosyltransferase, Arch. Biochem. Biophys. 303, 321-325.
-
(1993)
Arch. Biochem. Biophys
, vol.303
, pp. 321-325
-
-
Bhatia, M.B.1
Grubmeyer, C.2
-
35
-
-
0032900978
-
2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding
-
2+, and the inhibitor HPP reveals the involvement of the flexible loop in substrate binding, Protein Sci. 8, 1023-1031.
-
(1999)
Protein Sci
, vol.8
, pp. 1023-1031
-
-
Balendiran, G.K.1
Molina, J.A.2
Xu, Y.3
Torres-Martínez, J.4
Stevens, R.5
Focia, P.J.6
Eakin, A.E.7
Sacchettini, J.C.8
Craig III, S.P.9
-
36
-
-
0029990345
-
A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase
-
Henriksen, A., Aghajari, N., Jensen, K. F., and Gajhede, M. (1996) A flexible loop at the dimer interface is a part of the active site of the adjacent monomer of Escherichia coli orotate phosphoribosyltransferase, Biochemistry 35, 3803-3809.
-
(1996)
Biochemistry
, vol.35
, pp. 3803-3809
-
-
Henriksen, A.1
Aghajari, N.2
Jensen, K.F.3
Gajhede, M.4
-
37
-
-
0032497936
-
Approaching the transition state in the crystal structure of a phosphoribosyltransferase
-
Focia, P. J., Craig, S. P., III, and Eakin, A. E. (1998) Approaching the transition state in the crystal structure of a phosphoribosyltransferase, Biochemistry 37, 17120-17127.
-
(1998)
Biochemistry
, vol.37
, pp. 17120-17127
-
-
Focia, P.J.1
Craig III, S.P.2
Eakin, A.E.3
-
38
-
-
0016761094
-
Stereochemical course of the adenosine triphosphate phosphoribosyltransferase reaction in histidine biosynthesis
-
Chelsky, D., and Parsons, S. (1975) Stereochemical course of the adenosine triphosphate phosphoribosyltransferase reaction in histidine biosynthesis, J. Biol. Chem. 250, 5669-5673.
-
(1975)
J. Biol. Chem
, vol.250
, pp. 5669-5673
-
-
Chelsky, D.1
Parsons, S.2
-
39
-
-
0030070827
-
Transition state structure of Salmonella typhimurium orotate phosphoribosyltransferase
-
Tao, W., Grubmeyer, C., and Blanchard, J. S. (1996) Transition state structure of Salmonella typhimurium orotate phosphoribosyltransferase, Biochemistry, 35, 14-21.
-
(1996)
Biochemistry
, vol.35
, pp. 14-21
-
-
Tao, W.1
Grubmeyer, C.2
Blanchard, J.S.3
-
40
-
-
0029150167
-
Locations and functional roles of conserved lysine residues in Salmonella typhimurium orotate phosphoribosyltransferase
-
Ozturk, D. H., Dorfman, R. H., Scapin, G., Sacchettini, J. C., and Grubmeyer, C. (1995) Locations and functional roles of conserved lysine residues in Salmonella typhimurium orotate phosphoribosyltransferase, Biochemistry 34, 10755-10763.
-
(1995)
Biochemistry
, vol.34
, pp. 10755-10763
-
-
Ozturk, D.H.1
Dorfman, R.H.2
Scapin, G.3
Sacchettini, J.C.4
Grubmeyer, C.5
-
41
-
-
0036084699
-
MDB: The Metalloprotein Database and Browser at The Scripps Research Institute
-
Castagnetto, J. M., Hennessy, S. W., Roberts, V. A., Getzoff, E. D., Tainer, J. A., and Pique, M. E. (2002) MDB: the Metalloprotein Database and Browser at The Scripps Research Institute, Nucleic Acids Res. 30, 379-382.
-
(2002)
Nucleic Acids Res. 30
, pp. 379-382
-
-
Castagnetto, J.M.1
Hennessy, S.W.2
Roberts, V.A.3
Getzoff, E.D.4
Tainer, J.A.5
Pique, M.E.6
-
42
-
-
0026730771
-
Site-directed mutagenesis of a conserved domain in vaccinia virus thymidine kinase. Evidence for a potential role in magnesium binding
-
Black, M. E., and Hruby, D. E. (1992) Site-directed mutagenesis of a conserved domain in vaccinia virus thymidine kinase. Evidence for a potential role in magnesium binding, J. Biol. Chem. 267, 6801-6806.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 6801-6806
-
-
Black, M.E.1
Hruby, D.E.2
-
43
-
-
0026658556
-
Substitution of aspartic acid-80, a residue involved in coordination of magnesium, weakens the GTP binding and strongly enhances the GTPase of the G domain of elongation factor Tu
-
Harmark, K. M., Anborgh, P. H., Merola, M., Clark, B. F. C., and Parmeggiani, A. (1992) Substitution of aspartic acid-80, a residue involved in coordination of magnesium, weakens the GTP binding and strongly enhances the GTPase of the G domain of elongation factor Tu, Biochemistry 31, 7367-7372.
-
(1992)
Biochemistry
, vol.31
, pp. 7367-7372
-
-
Harmark, K.M.1
Anborgh, P.H.2
Merola, M.3
Clark, B.F.C.4
Parmeggiani, A.5
-
44
-
-
0033524459
-
Kinetic mechanism of OMP synthase: A slow physical step following group transfer limits catalytic rate
-
Wang, G. P., Lundegaard, C., Jensen, K. F., and Grubmeyer, C. (1999) Kinetic mechanism of OMP synthase: a slow physical step following group transfer limits catalytic rate, Biochemistry 38, 275-283.
-
(1999)
Biochemistry
, vol.38
, pp. 275-283
-
-
Wang, G.P.1
Lundegaard, C.2
Jensen, K.F.3
Grubmeyer, C.4
-
45
-
-
0345426287
-
The Structural Mechanism for Half-the-Sites Reactivity in an Enzyme, Thymidylate Synthase, involves a Relay of Changes between Subunits
-
Anderson, A. C., O'Neil, R. H., DeLano, W. L., and Stroud, R. M. (1999) The Structural Mechanism for Half-the-Sites Reactivity in an Enzyme, Thymidylate Synthase, involves a Relay of Changes between Subunits, Biochemistry 38, 13829-13836.
-
(1999)
Biochemistry
, vol.38
, pp. 13829-13836
-
-
Anderson, A.C.1
O'Neil, R.H.2
DeLano, W.L.3
Stroud, R.M.4
-
46
-
-
0013863816
-
Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits
-
Koshland, D. E., Jr., Nemethy, G., and Filmer, D. (1966) Comparison of Experimental Binding Data and Theoretical Models in Proteins Containing Subunits, Biochemistry 5, 365-385.
-
(1966)
Biochemistry
, vol.5
, pp. 365-385
-
-
Koshland Jr., D.E.1
Nemethy, G.2
Filmer, D.3
|