-
1
-
-
0027958452
-
Cloning and characterization of the cdna encoding a novel human pre b cell colony-enhancing factor
-
Samal, B., et al. Cloning and characterization of the cDNA encoding a novel human pre B cell colony-enhancing factor. Mol. Cell. Biol. 14, 1431-1437 (1994
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 1431-1437
-
-
Samal, B.1
-
2
-
-
0035145516
-
Identification of a plasmid-encoded gene from haemophilus ducreyi which confers nad independence
-
Martin, P. R., Shea, R. J., & Mulks, M. H. Identification of a plasmid-encoded gene from Haemophilus ducreyi which confers NAD independence. J. Bacteriol. 183, 1168-1174 (2001
-
(2001)
J. Bacteriol
, vol.183
, pp. 1168-1174
-
-
Martin, P.R.1
Shea, R.J.2
Mulks, M.H.3
-
3
-
-
0036856578
-
Pre b cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in nad biosynthesis
-
Rongvaux, A., et al. Pre B cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. Eur. J. Immunol. 32, 3225-3234 (2002
-
(2002)
Eur. J. Immunol
, vol.32
, pp. 3225-3234
-
-
Rongvaux, A.1
-
4
-
-
0038614824
-
Enzymatic synthesis of nicotinamide mononucleotide
-
Preiss, J., & Handler, P. Enzymatic synthesis of nicotinamide mononucleotide. J. Biol. Chem. 225, 759-770 (1957
-
(1957)
J. Biol. Chem
, vol.225
, pp. 759-770
-
-
Preiss, J.1
Handler, P.2
-
5
-
-
19944433652
-
Visfatin: A protein secreted by visceral fat that mimics the effects of insulin
-
Fukuhara, A., et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science. 307, 426-430 (2005
-
(2005)
Science
, vol.307
, pp. 426-430
-
-
Fukuhara, A.1
-
6
-
-
80052583612
-
Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: A meta-Analysis and systemic review
-
Chang, Y. H., Chang, D. M., Lin, K. C., Shin, S. J., & Lee, Y. J. Visfatin in overweight/obesity, type 2 diabetes mellitus, insulin resistance, metabolic syndrome and cardiovascular diseases: a meta-Analysis and systemic review. Diabetes Metab. Res. Rev. 27, 515-527 (2011
-
(2011)
Diabetes Metab. Res. Rev
, vol.27
, pp. 515-527
-
-
Chang, Y.H.1
Chang, D.M.2
Lin, K.C.3
Shin, S.J.4
Lee, Y.J.5
-
7
-
-
62649156291
-
Nampt: Linking nad biology, metabolism and cancer
-
Garten, A., Petzold, S., Körner, A., Imai, S., & Kiess, W. Nampt: linking NAD biology, metabolism and cancer. Trends Endocrinol. Metab. 20, 130-138 (2009
-
(2009)
Trends Endocrinol. Metab
, vol.20
, pp. 130-138
-
-
Garten, A.1
Petzold, S.2
Körner, A.3
Imai, S.4
Kiess, W.5
-
8
-
-
84912572145
-
Metabolic profiling of alternative nad biosynthetic routes in mouse tissues
-
Mori, V., et al. Metabolic profiling of alternative NAD biosynthetic routes in mouse tissues. PLoS ONE. 9, e113939 (2014
-
(2014)
PLoS ONE
, vol.9
, pp. e113939
-
-
Mori, V.1
-
9
-
-
84889594248
-
Nicotinamide improves glucose metabolism and affects the hepatic nad-sirtuin pathway in a rodent model of obesity and type 2 diabetes
-
Yang, S. J., et al. Nicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetes. J. Nutr. Biochem. 25, 66-72 (2014
-
(2014)
J. Nutr. Biochem
, vol.25
, pp. 66-72
-
-
Yang, S.J.1
-
10
-
-
0015500271
-
The management of nicotinamide and nicotinic acid in the mouse
-
Collins, P. B., & Chaykin, S. The management of nicotinamide and nicotinic acid in the mouse. J. Biol. Chem. 247, 778-783 (1972
-
(1972)
J. Biol. Chem
, vol.247
, pp. 778-783
-
-
Collins, P.B.1
Chaykin, S.2
-
11
-
-
0023219691
-
Purification and characterization of poly(adp-ribose) synthetase from human placenta
-
Ushiro, H., Yokoyama, Y., & Shizuta, Y. Purification and characterization of poly(ADP-ribose) synthetase from human placenta. J. Biol. Chem. 262, 2352-2357 (1987
-
(1987)
J. Biol. Chem
, vol.262
, pp. 2352-2357
-
-
Ushiro, H.1
Yokoyama, Y.2
Shizuta, Y.3
-
12
-
-
84907145662
-
Mechanism of inhibition of the human sirtuin enzyme sirt3 by nicotinamide: Computational and experimental studies
-
Guan, X., Lin, P., Knoll, E., & Chakrabarti, R. Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studies. PLoS ONE. 9, e107729 (2014
-
(2014)
PLoS ONE
, vol.9
, pp. e107729
-
-
Guan, X.1
Lin, P.2
Knoll, E.3
Chakrabarti, R.4
-
13
-
-
0037160097
-
Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human sirt1
-
Bitterman, K. J., Anderson, R. M., Cohen, H. Y., Latorre-Esteves, M., & Sinclair, D. A. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J. Biol. Chem. 277, 45099-45107 (2002
-
(2002)
J. Biol. Chem
, vol.277
, pp. 45099-45107
-
-
Bitterman, K.J.1
Anderson, R.M.2
Cohen, H.Y.3
Latorre-Esteves, M.4
Sinclair, D.A.5
-
14
-
-
10944270187
-
The nad biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates sir2 activity in mammalian cells
-
Revollo, J. R., Grimm, A. A., & Imai, S. The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J. Biol. Chem. 279, 50754-50763 (2004
-
(2004)
J. Biol. Chem
, vol.279
, pp. 50754-50763
-
-
Revollo, J.R.1
Grimm, A.A.2
Imai, S.3
-
15
-
-
2342550554
-
Discoveries of nicotinamide riboside as a nutrient and conserved nrk genes establish a preiss-handler independent route to nad+ in fungi and humans
-
Bieganowski, P., & Brenner, C. Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans. Cell. 117, 495-502 (2004
-
(2004)
Cell
, vol.117
, pp. 495-502
-
-
Bieganowski, P.1
Brenner, C.2
-
16
-
-
79957549799
-
Pathways and subcellular compartmentation of NAD biosynthesis in human cells: From entry of extracellular precursors to mitochondrial NAD generation
-
Nikiforov, A., Dölle, C., Niere, M., & Ziegler, M. Pathways and subcellular compartmentation of NAD biosynthesis in human cells: from entry of extracellular precursors to mitochondrial NAD generation. J. Biol. Chem. 286, 21767-21778 (2011
-
(2011)
J. Biol. Chem
, vol.286
, pp. 21767-21778
-
-
Nikiforov, A.1
Dölle, C.2
Niere, M.3
Ziegler, M.4
-
17
-
-
84055223632
-
The high-resolution crystal structure of periplasmic haemophilus influenzae nad nucleotidase reveals a novel enzymatic function of human cd73 related to nad metabolism
-
Garavaglia, S., et al. The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism. Biochem. J. 441, 131-141 (2012
-
(2012)
Biochem. J.
, vol.441
, pp. 131-141
-
-
Garavaglia, S.1
-
18
-
-
84883738070
-
Cd73 protein as a source of extracellular precursors for sustained nad+ biosynthesis in fk866-Treated tumor cells
-
Grozio, A., et al. CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-Treated tumor cells. J. Biol. Chem. 288, 25938-25949 (2013
-
(2013)
J. Biol. Chem
, vol.288
, pp. 25938-25949
-
-
Grozio, A.1
-
19
-
-
79954634068
-
Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (nampt)/pre b cell colony (pbef)/visfatin linking obesity and inflammation in humans
-
Friebe, D., et al. Leucocytes are a major source of circulating nicotinamide phosphoribosyltransferase (NAMPT)/pre B cell colony (PBEF)/visfatin linking obesity and inflammation in humans. Diabetologia. 54, 1200-1211 (2011
-
(2011)
Diabetologia
, vol.54
, pp. 1200-1211
-
-
Friebe, D.1
-
20
-
-
0038356712
-
Growth phase-dependent changes in the subcellular localization of pre b cell colony-enhancing factor
-
Kitani, T., Okuno, S., & Fujisawa, H. Growth phase-dependent changes in the subcellular localization of pre B cell colony-enhancing factor. FEBS Lett. 544, 74-78 (2003
-
(2003)
FEBS Lett
, vol.544
, pp. 74-78
-
-
Kitani, T.1
Okuno, S.2
Fujisawa, H.3
-
21
-
-
35549002189
-
Nampt/pbef/visfatin regulates insulin secretion in β cells as a systemic nad biosynthetic enzyme
-
Revollo, J. R., et al. Nampt/PBEF/visfatin regulates insulin secretion in β cells as a systemic NAD biosynthetic enzyme. Cell Metab. 6, 363-375 (2007
-
(2007)
Cell Metab
, vol.6
, pp. 363-375
-
-
Revollo, J.R.1
-
22
-
-
34548627517
-
Nutrient-sensitive mitochondrial nad+ levels dictate cell survival
-
Yang, H., et al. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell. 130, 1095-1107 (2007
-
(2007)
Cell
, vol.130
, pp. 1095-1107
-
-
Yang, H.1
-
23
-
-
77958569431
-
Inhibition of nicotinamide phosphoribosyltransferase: Cellular bioenergetics reveals a mitochondrial insensitive nad pool
-
Pittelli, M., et al. Inhibition of nicotinamide phosphoribosyltransferase: cellular bioenergetics reveals a mitochondrial insensitive NAD pool. J. Biol. Chem. 285, 34106-34114 (2010
-
(2010)
J. Biol. Chem
, vol.285
, pp. 34106-34114
-
-
Pittelli, M.1
-
24
-
-
54349088713
-
Weak coupling of atp hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase
-
Burgos, E. S., & Schramm, V. L. Weak coupling of ATP hydrolysis to the chemical equilibrium of human nicotinamide phosphoribosyltransferase. Biochemistry. 47, 11086-11096 (2008
-
(2008)
Biochemistry
, vol.47
, pp. 11086-11096
-
-
Burgos, E.S.1
Schramm, V.L.2
-
25
-
-
33747624726
-
Crystal structure of visfatin/pre b cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent fk 866
-
Kim, M. K., et al. Crystal structure of visfatin/pre B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK 866. J. Mol. Biol. 362, 66-77 (2006
-
(2006)
J. Mol. Biol
, vol.362
, pp. 66-77
-
-
Kim, M.K.1
-
26
-
-
33745862384
-
Structure of nampt/pbef/visfatin, a mammalian nad+ biosynthetic enzyme
-
Wang, T., et al. Structure of Nampt/PBEF/visfatin, a mammalian NAD+ biosynthetic enzyme. Nat. Struct. Mol. Biol. 13, 661-662 (2006
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 661-662
-
-
Wang, T.1
-
27
-
-
67650314923
-
Crystal structure of rattus norvegicus visfatin/pbef/nampt in complex with an fk866-based inhibitor
-
Kang, G. B., et al. Crystal structure of Rattus norvegicus visfatin/PBEF/Nampt in complex with an FK866-based inhibitor. Mol. Cells. 27, 667-671 (2009
-
(2009)
Mol. Cells
, vol.27
, pp. 667-671
-
-
Kang, G.B.1
-
28
-
-
84874908355
-
Recycling nicotinamide the transition-state structure of human nicotinamide phosphoribosyltransferase
-
Burgos, E. S., Vetticatt, M. J., & Schramm, V. L. Recycling nicotinamide. The transition-state structure of human nicotinamide phosphoribosyltransferase. J. Am. Chem. Soc. 135, 3485-3493 (2013
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 3485-3493
-
-
Burgos, E.S.1
Vetticatt, M.J.2
Schramm, V.L.3
-
29
-
-
33745817828
-
Molecular basis for the inhibition of human nmprtase, a novel target for anticancer agents
-
Khan, J. A., Tao, X., & Tong, L. Molecular basis for the inhibition of human NMPRTase, a novel target for anticancer agents. Nat. Struct. Mol. Biol. 13, 582-588 (2006
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 582-588
-
-
Khan, J.A.1
Tao, X.2
Tong, L.3
-
30
-
-
34248216056
-
Crystallization of human nicotinamide phosphoribosyltransferase
-
Takahashi, R., Nakamura, S., Yoshida, T., Kobayashi, Y., & Ohkubo, T. Crystallization of human nicotinamide phosphoribosyltransferase. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63, 375-377 (2007
-
(2007)
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun
, vol.63
, pp. 375-377
-
-
Takahashi, R.1
Nakamura, S.2
Yoshida, T.3
Kobayashi, Y.4
Ohkubo, T.5
-
31
-
-
84889261827
-
Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-Activity relationship
-
Christensen, M. K., et al. Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-Activity relationship. J. Med. Chem. 56, 9071-9088 (2013
-
(2013)
J. Med. Chem
, vol.56
, pp. 9071-9088
-
-
Christensen, M.K.1
-
32
-
-
0242526050
-
Fk866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
-
Hasmann, M., & Schemainda, I. FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res. 63, 7436-7442 (2003
-
(2003)
Cancer Res
, vol.63
, pp. 7436-7442
-
-
Hasmann, M.1
Schemainda, I.2
-
33
-
-
84863090408
-
Nicotinamide phosphoribosyl transferase (nampt) is required for de novo lipogenesis in tumor cells
-
Bowlby, S. C., Thomas, M. J., D'Agostino, R. B., & Kridel, S. J. Nicotinamide phosphoribosyl transferase (Nampt) is required for de novo lipogenesis in tumor cells. PLoS ONE. 7, e40195 (2012
-
(2012)
PLoS ONE
, vol.7
, pp. e40195
-
-
Bowlby, S.C.1
Thomas, M.J.2
D'agostino, R.B.3
Kridel, S.J.4
-
34
-
-
70949092805
-
Catastrophic nad+ depletion in activated t lymphocytes through nampt inhibition reduces demyelination and disability in eae
-
Bruzzone, S., et al. Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE. PLoS ONE. 4, e7897 (2009
-
(2009)
PLoS ONE
, vol.4
, pp. e7897
-
-
Bruzzone, S.1
-
35
-
-
74149085437
-
Exercise alters sirt1, sirt6, nad and nampt levels in skeletal muscle of aged rats
-
Koltai, E., et al. Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats. Mech. Ageing Dev. 131, 21-28 (2010
-
(2010)
Mech. Ageing Dev
, vol.131
, pp. 21-28
-
-
Koltai, E.1
-
36
-
-
59649117804
-
Intracellular nad levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
-
Van Gool, F., et al. Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner. Nat. Med. 15, 206-210 (2009
-
(2009)
Nat. Med
, vol.15
, pp. 206-210
-
-
Van Gool, F.1
-
37
-
-
30044443515
-
Poly(adp-ribose) polymerase 1 dependent cardiac myocyte cell death during heart failure is mediated by nad+ depletion and reduced sir2a deacetylase activity
-
Pillai, J. B., Isbatan, A., Imai, S., & Gupta, M. P. Poly(ADP-ribose) polymerase 1 dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2a deacetylase activity. J. Biol. Chem. 280, 43121-43130 (2005
-
(2005)
J. Biol. Chem
, vol.280
, pp. 43121-43130
-
-
Pillai, J.B.1
Isbatan, A.2
Imai, S.3
Gupta, M.P.4
-
38
-
-
37349110355
-
Metabolic adaptations through the pgc 1 a and sirt1 pathways
-
Rodgers, J. T., Lerin, C., Gerhart-Hines, Z., & Puigserver, P. Metabolic adaptations through the PGC 1 a and SIRT1 pathways. FEBS Lett. 582, 46-53 (2008
-
(2008)
FEBS Lett
, vol.582
, pp. 46-53
-
-
Rodgers, J.T.1
Lerin, C.2
Gerhart-Hines, Z.3
Puigserver, P.4
-
39
-
-
3142742707
-
Foxo4 is acetylated upon peroxide stress and deacetylated by the longevity protein hsir2 (sirt1
-
Van der Horst, A., et al. FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2 (SIRT1). J. Biol. Chem. 279, 28873-28879 (2004
-
(2004)
J. Biol. Chem
, vol.279
, pp. 28873-28879
-
-
Van Der Horst, A.1
-
40
-
-
33244486764
-
Sirt1 regulates insulin secretion by repressing ucp2 in pancreatic β cells
-
Bordone, L., et al. Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic β cells. PLoS Biol. 4, e31 (2006
-
(2006)
PLoS Biol
, vol.4
, pp. e31
-
-
Bordone, L.1
-
41
-
-
84857891632
-
On par with parp: Cellular stress signaling through poly(adp-ribose) and parp 1
-
Luo, X., & Kraus, W. L. on PAR with PARP: Cellular Stress Signaling Through Poly(ADP-ribose) and PARP 1. Genes Dev. 26, 417-432 (2012
-
(2012)
Genes dev
, vol.26
, pp. 417-432
-
-
Luo, X.1
Kraus, W.L.2
-
42
-
-
84880879892
-
Nad+ metabolism: A therapeutic target for age-related metabolic disease
-
Mouchiroud, L., Houtkooper, R. H., & Auwerx, J. NAD+ metabolism: a therapeutic target for age-related metabolic disease. Crit. Rev. Biochem. Mol. Biol. 48, 397-408 (2013
-
(2013)
Crit. Rev. Biochem. Mol. Biol
, vol.48
, pp. 397-408
-
-
Mouchiroud, L.1
Houtkooper, R.H.2
Auwerx, J.3
-
43
-
-
84889046051
-
Nad biosynthesis in humans-enzymes, metabolites and therapeutic aspects
-
Dölle, C., Skoge, R. H., Vanlinden, M. R., & Ziegler, M. NAD biosynthesis in humans-enzymes, metabolites and therapeutic aspects. Curr. Top. Med. Chem. 13, 2907-2917 (2013
-
(2013)
Curr. Top. Med. Chem
, vol.13
, pp. 2907-2917
-
-
Dölle, C.1
Skoge, R.H.2
Vanlinden, M.R.3
Ziegler, M.4
-
44
-
-
84894352303
-
Sirt1 and other sirtuins in metabolism
-
Chang, H. C., & Guarente, L. SIRT1 and other sirtuins in metabolism. Trends Endocrinol. Metab. 25, 138-145 (2014
-
(2014)
Trends Endocrinol. Metab
, vol.25
, pp. 138-145
-
-
Chang, H.C.1
Guarente, L.2
-
45
-
-
63849252078
-
Therapeutic potential of sirt1 and nampt-mediated nad biosynthesis in type 2 diabetes
-
Imai, S., & Kiess, W. Therapeutic potential of SIRT1 and NAMPT-mediated NAD biosynthesis in type 2 diabetes. Front. Biosci. (Landmark Ed.) 14, 2983-2995 (2009
-
(2009)
Front. Biosci. (Landmark Ed.
, vol.14
, pp. 2983-2995
-
-
Imai, S.1
Kiess, W.2
-
46
-
-
84886723521
-
Poly(adp-ribose): Paradigms and paradoxes
-
Bürkle, A., & Virág, L. Poly(ADP-ribose): PARadigms and PARadoxes. Mol. Aspects Med. 34, 1046-1065 (2013
-
(2013)
Mol. Aspects Med
, vol.34
, pp. 1046-1065
-
-
Bürkle, A.1
Virág, L.2
-
47
-
-
84880333963
-
A role of intracellular mono adp ribosylation in cancer biology
-
Scarpa, E. S., Fabrizio, G., & Di Girolamo, M. A role of intracellular mono ADP ribosylation in cancer biology. FEBS J. 280, 3551-3562 (2013
-
(2013)
FEBS J.
, vol.280
, pp. 3551-3562
-
-
Scarpa, E.S.1
Fabrizio, G.2
Di Girolamo, M.3
-
48
-
-
14844354701
-
Adp-ribosyl cyclase: An enzyme that cyclizes nad+ into a calcium-mobilizing metabolite
-
Lee, H. C., & Aarhus, R. ADP-ribosyl cyclase: an enzyme that cyclizes NAD+ into a calcium-mobilizing metabolite. Cell Regul. 2, 203-209 (1991
-
(1991)
Cell Regul
, vol.2
, pp. 203-209
-
-
Lee, H.C.1
Aarhus, R.2
-
49
-
-
65549103855
-
Circadian clock feedback cycle through nampt-mediated nad+ biosynthesis
-
Ramsey, K. M., et al. Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis. Science. 324, 651-654 (2009
-
(2009)
Science
, vol.324
, pp. 651-654
-
-
Ramsey, K.M.1
-
50
-
-
65549118773
-
Circadian control of the nad+ salvage pathway by clock-sirt1
-
Nakahata, Y., Sahar, S., Astarita, G., Kaluzova, M., & Sassone-Corsi, P. Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1. Science. 324, 654-657 (2009
-
(2009)
Science
, vol.324
, pp. 654-657
-
-
Nakahata, Y.1
Sahar, S.2
Astarita, G.3
Kaluzova, M.4
Sassone-Corsi, P.5
-
51
-
-
36849020047
-
Molecular characteristics of serum visfatin and differential detection by immunoassays
-
Korner, A., et al. Molecular characteristics of serum visfatin and differential detection by immunoassays. J. Clin. Endocrinol. Metab. 92, 4783-4791 (2007
-
(2007)
J. Clin. Endocrinol. Metab
, vol.92
, pp. 4783-4791
-
-
Korner, A.1
-
52
-
-
62749111474
-
Relationship between cerebrospinal fluid visfatin (pbef/nampt) levels and adiposity in humans
-
Hallschmid, M., Randeva, H., Tan, B. K., Kern, W., & Lehnert, H. Relationship between cerebrospinal fluid visfatin (PBEF/Nampt) levels and adiposity in humans. Diabetes. 58, 637-640 (2009
-
(2009)
Diabetes
, vol.58
, pp. 637-640
-
-
Hallschmid, M.1
Randeva, H.2
Tan, B.K.3
Kern, W.4
Lehnert, H.5
-
53
-
-
84875754584
-
Seminal plasma adipokine levels are correlated with functional characteristics of spermatozoa
-
Thomas, S., et al. Seminal plasma adipokine levels are correlated with functional characteristics of spermatozoa. Fertil. Steril. 99, 1256-1263 (2013
-
(2013)
Fertil. Steril
, vol.99
, pp. 1256-1263
-
-
Thomas, S.1
-
54
-
-
34249950921
-
Visfatin is released from 3t3 l1 adipocytes via a non-classical pathway
-
Tanaka, M., et al. Visfatin is released from 3T3 L1 adipocytes via a non-classical pathway. Biochem. Biophys. Res. Commun. 359, 194-201 (2007
-
(2007)
Biochem. Biophys. Res. Commun
, vol.359
, pp. 194-201
-
-
Tanaka, M.1
-
55
-
-
84928174797
-
Sirt1-mediated enampt secretion from adipose tissue regulates hypothalamic nad+ and function in mice
-
Yoon, M. J., et al. SIRT1-mediated eNAMPT secretion from adipose tissue regulates hypothalamic NAD+ and function in mice. Cell. Metab. 21, 706-717 (2015
-
(2015)
Cell. Metab
, vol.21
, pp. 706-717
-
-
Yoon, M.J.1
-
56
-
-
72949097428
-
Nicotinamide phosphoribosyltransferase (nampt/pbef/visfatin) is constitutively released from human hepatocytes
-
Garten, A., et al. Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes. Biochem. Biophys. Res. Commun. 391, 376-381 (2010
-
(2010)
Biochem. Biophys. Res. Commun
, vol.391
, pp. 376-381
-
-
Garten, A.1
-
57
-
-
84897137060
-
Resveratrol differentially regulates nampt and sirt1 in hepatocarcinoma cells and primary human hepatocytes
-
Schuster, S., et al. Resveratrol differentially regulates NAMPT and SIRT1 in hepatocarcinoma cells and primary human hepatocytes. PLoS ONE. 9, e91045 (2014
-
(2014)
PLoS ONE
, vol.9
, pp. e91045
-
-
Schuster, S.1
-
58
-
-
84873293264
-
Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling
-
Pillai, V. B., et al. Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling. Am. J. Physiol. Heart Circ. Physiol. 304, H415-H426 (2013
-
(2013)
Am. J. Physiol. Heart Circ. Physiol
, vol.304
, pp. H415-H426
-
-
Pillai, V.B.1
-
59
-
-
84893683574
-
Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism
-
Zhao, B., et al. Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism. PLoS ONE. 8, e85403 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e85403
-
-
Zhao, B.1
-
60
-
-
84921742607
-
Neuronal nampt is released after cerebral ischemia and protects against white matter injury
-
Jing, Z., et al. Neuronal NAMPT is released after cerebral ischemia and protects against white matter injury. J. Cereb. Blood Flow Metab. 34, 1613-1621 (2014
-
(2014)
J. Cereb. Blood Flow Metab
, vol.34
, pp. 1613-1621
-
-
Jing, Z.1
-
61
-
-
0036795752
-
Pre b cell colony-enhancing factor, a novel cytokine of human fetal membranes
-
Ognjanovic, S., & Bryant-Greenwood, G. D. Pre B cell colony-enhancing factor, a novel cytokine of human fetal membranes. Am. J. Obstet. Gynecol. 187, 1051-1058 (2002
-
(2002)
Am. J. Obstet. Gynecol
, vol.187
, pp. 1051-1058
-
-
Ognjanovic, S.1
Bryant-Greenwood, G.D.2
-
62
-
-
84874820984
-
Expression and regulation of nampt in human islets
-
Kover, K., et al. Expression and regulation of nampt in human islets. PLoS ONE. 8, e58767 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e58767
-
-
Kover, K.1
-
63
-
-
84867092344
-
Extracellular atp induces p2x7-dependent nicotinamide phosphoribosyltransferase release in lps-Activated human monocytes
-
Schilling, E., & Hauschildt, S. Extracellular ATP induces P2X7-dependent nicotinamide phosphoribosyltransferase release in LPS-Activated human monocytes. Innate Immun. 18, 738-744 (2012
-
(2012)
Innate Immun
, vol.18
, pp. 738-744
-
-
Schilling, E.1
Hauschildt, S.2
-
64
-
-
84859514605
-
Monocytes contribute to differential immune pressure on r5 versus x4 HIV through the adipocytokine visfatin/nampt
-
Van den Bergh, R., et al. Monocytes contribute to differential immune pressure on R5 versus X4 HIV through the adipocytokine visfatin/NAMPT. PLoS ONE. 7, e35074 (2012
-
(2012)
PLoS ONE
, vol.7
, pp. e35074
-
-
Van Den Bergh, R.1
-
65
-
-
84899476892
-
Extracellular visfatin activates gluconeogenesis in hepg2 cells through the classical pka/creb-dependent pathway
-
Choi, Y. J., et al. Extracellular visfatin activates gluconeogenesis in HepG2 cells through the classical PKA/CREB-dependent pathway. Horm. Metab. Res. 46, 233-239 (2014
-
(2014)
Horm. Metab. Res
, vol.46
, pp. 233-239
-
-
Choi, Y.J.1
-
66
-
-
34147118466
-
Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2
-
Kim, S. R., et al. Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2. Biochem. Biophys. Res. Commun. 357, 150-156 (2007
-
(2007)
Biochem. Biophys. Res. Commun
, vol.357
, pp. 150-156
-
-
Kim, S.R.1
-
67
-
-
58149499166
-
Upregulation of fibroblast growth factor 2 by visfatin that promotes endothelial angiogenesis
-
Bae, Y. H., et al. Upregulation of fibroblast growth factor 2 by visfatin that promotes endothelial angiogenesis. Biochem. Biophys. Res. Commun. 379, 206-211 (2009
-
(2009)
Biochem. Biophys. Res. Commun
, vol.379
, pp. 206-211
-
-
Bae, Y.H.1
-
68
-
-
80053950921
-
Visfatin induces neurite outgrowth in pc12 cells via erk1/2 signaling pathway
-
Kang, Y. S., et al. Visfatin induces neurite outgrowth in PC12 cells via ERK1/2 signaling pathway. Neurosci. Lett. 504, 121-126 (2011
-
(2011)
Neurosci. Lett
, vol.504
, pp. 121-126
-
-
Kang, Y.S.1
-
69
-
-
84905046221
-
Visfatin promotes cell and tumor growth by upregulating notch1 in breast cancer
-
Park, H. J., et al. Visfatin promotes cell and tumor growth by upregulating Notch1 in breast cancer. Oncotarget. 5, 5087-5099 (2014
-
(2014)
Oncotarget
, vol.5
, pp. 5087-5099
-
-
Park, H.J.1
-
70
-
-
84910142746
-
Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of nad+ biosynthetic machinery in mammalian cells
-
Zamporlini, F., et al. Novel assay for simultaneous measurement of pyridine mononucleotides synthesizing activities allows dissection of NAD+ biosynthetic machinery in mammalian cells. FEBS J. 281, 5104-5119 (2014
-
(2014)
FEBS J.
, vol.281
, pp. 5104-5119
-
-
Zamporlini, F.1
-
71
-
-
64049094455
-
Detection and pharmacological modulation of nicotinamide mononucleotide (nmn) in vitro and in vivo
-
Formentini, L., Moroni, F., & Chiarugi, A. Detection and pharmacological modulation of nicotinamide mononucleotide (NMN) in vitro and in vivo. Biochem. Pharmacol. 77, 1612-1620 (2009
-
(2009)
Biochem. Pharmacol
, vol.77
, pp. 1612-1620
-
-
Formentini, L.1
Moroni, F.2
Chiarugi, A.3
-
72
-
-
79961085079
-
Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma
-
Hara, N., Yamada, K., Shibata, T., Osago, H., & Tsuchiya, M. Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma. PLoS ONE. 6, e22781 (2011
-
(2011)
PLoS ONE
, vol.6
, pp. e22781
-
-
Hara, N.1
Yamada, K.2
Shibata, T.3
Osago, H.4
Tsuchiya, M.5
-
73
-
-
84928600816
-
Adipose tissue and adipokines: The association with and application of adipokines in obesity
-
Khan, M., & Joseph, F. Adipose tissue and adipokines: the association with and application of adipokines in obesity. Scientifica (Cairo) 2014, 328592 (2014
-
(2014)
Scientifica (Cairo
, vol.2014
, pp. 328592
-
-
Khan, M.1
Joseph, F.2
-
74
-
-
84859524069
-
Adipocytes as a source of increased circulating levels of nicotinamide phosphoribosyltransferase/visfatin in active acromegaly
-
Olarescu, N. C., et al. Adipocytes as a source of increased circulating levels of nicotinamide phosphoribosyltransferase/visfatin in active acromegaly. J. Clin. Endocrinol. Metab. 97, 1355-1362 (2012
-
(2012)
J. Clin. Endocrinol. Metab
, vol.97
, pp. 1355-1362
-
-
Olarescu, N.C.1
-
75
-
-
67749146993
-
A rare variant in the visfatin gene (nampt/pbef1) is associated with protection from obesity
-
Blakemore, A. I., et al. A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity. Obesity (Silver Spring) 17, 1549-1553 (2009
-
(2009)
Obesity (Silver Spring
, vol.17
, pp. 1549-1553
-
-
Blakemore, A.I.1
-
76
-
-
84882542091
-
Association of circulating levels of nicotinamide phosphoribosyltransferase (nampt/visfatin) and of a frequent polymorphism in the promoter of the nampt gene with coronary artery disease in diabetic and non-diabetic subjects
-
Saddi-Rosa, P., et al. Association of circulating levels of nicotinamide phosphoribosyltransferase (NAMPT/Visfatin) and of a frequent polymorphism in the promoter of the NAMPT gene with coronary artery disease in diabetic and non-diabetic subjects. Cardiovasc. Diabetol. 12, 119 (2013
-
(2013)
Cardiovasc. Diabetol
, vol.12
, pp. 119
-
-
Saddi-Rosa, P.1
-
77
-
-
33747511443
-
The visfatin gene is associated with glucose and lipid metabolism in a Chinese population
-
Jian, W. X., et al. The visfatin gene is associated with glucose and lipid metabolism in a Chinese population. Diabet. Med. 23, 967-973 (2006
-
(2006)
Diabet. Med
, vol.23
, pp. 967-973
-
-
Jian, W.X.1
-
78
-
-
77953356423
-
Genetic variation in the visfatin (pbef1/nampt) gene and type 2 diabetes in the Greek population
-
Paschou, P., et al. Genetic variation in the visfatin (PBEF1/NAMPT) gene and type 2 diabetes in the Greek population. Cytokine. 51, 25-27 (2010
-
(2010)
Cytokine
, vol.51
, pp. 25-27
-
-
Paschou, P.1
-
79
-
-
34248336647
-
Effects of genetic variation in the visfatin gene (pbef1) on obesity, glucose metabolism, and blood pressure in children
-
Körner, A., et al. Effects of genetic variation in the visfatin gene (PBEF1) on obesity, glucose metabolism, and blood pressure in children. Metabolism. 56, 772-777 (2007
-
(2007)
Metabolism
, vol.56
, pp. 772-777
-
-
Körner, A.1
-
80
-
-
33745792380
-
Genetic variation in the visfatin gene (pbef1) and its relation to glucose metabolism and fat depot specific messenger ribonucleic acid expression in humans
-
Böttcher, Y., et al. Genetic variation in the visfatin gene (PBEF1) and its relation to glucose metabolism and fat depot specific messenger ribonucleic acid expression in humans. J. Clin. Endocrinol. Metab. 91, 2725-2731 (2006
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, pp. 2725-2731
-
-
Böttcher, Y.1
-
81
-
-
33745789837
-
The release of the adipocytokine visfatin is regulated by glucose and insulin
-
Haider, D. G., et al. The release of the adipocytokine visfatin is regulated by glucose and insulin. Diabetologia. 49, 1909-1914 (2006
-
(2006)
Diabetologia
, vol.49
, pp. 1909-1914
-
-
Haider, D.G.1
-
82
-
-
33646052892
-
Increased plasma visfatin concentrations in morbidly obese subjects are reduced after gastric banding
-
Haider, D. G., et al. Increased plasma visfatin concentrations in morbidly obese subjects are reduced after gastric banding. J. Clin. Endocrinol. Metab. 91, 1578-1581 (2006
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, pp. 1578-1581
-
-
Haider, D.G.1
-
83
-
-
84896695185
-
Ox-ldl induces er stress and promotes the adipokines secretion in 3t3 l1 adipocytes
-
Chen, Y., Chen, M., Wu, Z., & Zhao, S. Ox-LDL induces ER stress and promotes the adipokines secretion in 3T3 L1 adipocytes. PLoS ONE. 8, e81379 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e81379
-
-
Chen, Y.1
Chen, M.2
Wu, Z.3
Zhao, S.4
-
84
-
-
21244474768
-
Hormonal regulation of the novel adipocytokine visfatin in 3t3 l1 adipocytes
-
Kralisch, S., et al. Hormonal regulation of the novel adipocytokine visfatin in 3T3 L1 adipocytes. J. Endocrinol. 185, R1-R8 (2005
-
(2005)
J. Endocrinol
, vol.185
, pp. R1-R8
-
-
Kralisch, S.1
-
85
-
-
25144508518
-
Interleukin 6 is a negative regulator of visfatin gene expression in 3t3 l1 adipocytes
-
Kralisch, S., et al. Interleukin 6 is a negative regulator of visfatin gene expression in 3T3 L1 adipocytes. Am. J. Physiol. Endocrinol. Metab. 289, E586-E590 (2005
-
(2005)
Am. J. Physiol. Endocrinol. Metab
, vol.289
, pp. E586-E590
-
-
Kralisch, S.1
-
86
-
-
79958140016
-
Impact of metabolic regulators on the expression of the obesity associated genes fto and nampt in human preadipocytes and adipocytes
-
Friebe, D., et al. Impact of metabolic regulators on the expression of the obesity associated genes FTO and NAMPT in human preadipocytes and adipocytes. PLoS ONE. 6, e19526 (2011
-
(2011)
PLoS ONE
, vol.6
, pp. e19526
-
-
Friebe, D.1
-
87
-
-
84896046211
-
Blockade of visfatin induction by oleanolic acid via disturbing il 6 traf6 nf ?b signaling of adipocytes
-
Kim, H. S., et al. Blockade of visfatin induction by oleanolic acid via disturbing IL 6 TRAF6 NF ?B signaling of adipocytes. Exp. Biol. Med. (Maywood) 239, 284-292 (2014
-
(2014)
Exp. Biol. Med. (Maywood
, vol.239
, pp. 284-292
-
-
Kim, H.S.1
-
88
-
-
33748596091
-
Visfatin in adipocytes is upregulated by hypoxia through hif1a-dependent mechanism
-
Segawa, K., et al. Visfatin in adipocytes is upregulated by hypoxia through HIF1a-dependent mechanism. Biochem. Biophys. Res. Commun. 349, 875-882 (2006
-
(2006)
Biochem. Biophys. Res. Commun
, vol.349
, pp. 875-882
-
-
Segawa, K.1
-
89
-
-
33644826101
-
Macrophages in human visceral adipose tissue: Increased accumulation in obesity and a source of resistin and visfatin
-
Curat, C. A., et al. Macrophages in human visceral adipose tissue: increased accumulation in obesity and a source of resistin and visfatin. Diabetologia. 49, 744-747 (2006
-
(2006)
Diabetologia
, vol.49
, pp. 744-747
-
-
Curat, C.A.1
-
90
-
-
84880154046
-
Visfatin/nampt: An adipokine with cardiovascular impact
-
Romacho, T., Sánchez-Ferrer, C. F., & Peiró, C. Visfatin/Nampt: an adipokine with cardiovascular impact. Mediators Inflamm. 2013, 946427 (2013
-
(2013)
Mediators Inflamm
, vol.2013
, pp. 946427
-
-
Romacho, T.1
Sánchez-Ferrer, C.F.2
Peiró, C.3
-
91
-
-
58049200121
-
Extracellular nampt promotes macrophage survival via a nonenzymatic interleukin 6/stat3 signaling mechanism
-
Li, Y., et al. Extracellular Nampt promotes macrophage survival via a nonenzymatic interleukin 6/STAT3 signaling mechanism. J. Biol. Chem. 283, 34833-34843 (2008
-
(2008)
J. Biol. Chem
, vol.283
, pp. 34833-34843
-
-
Li, Y.1
-
92
-
-
70349849659
-
Extracellular pbef/nampt/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity
-
Romacho, T., et al. Extracellular PBEF/NAMPT/visfatin activates pro-inflammatory signalling in human vascular smooth muscle cells through nicotinamide phosphoribosyltransferase activity. Diabetologia. 52, 2455-2463 (2009
-
(2009)
Diabetologia
, vol.52
, pp. 2455-2463
-
-
Romacho, T.1
-
93
-
-
77953530684
-
Pre b cell colony enhancing factor/nampt/visfatin in inflammation and obesity-related disorders
-
Moschen, A. R., Gerner, R. R., & Tilg, H. Pre B cell colony enhancing factor/NAMPT/visfatin in inflammation and obesity-related disorders. Curr. Pharm. Des. 16, 1913-1920 (2010
-
(2010)
Curr. Pharm. des
, vol.16
, pp. 1913-1920
-
-
Moschen, A.R.1
Gerner, R.R.2
Tilg, H.3
-
94
-
-
34248218011
-
TNF a alters visfatin and adiponectin levels in human fat
-
Hector, J., et al. TNF a alters visfatin and adiponectin levels in human fat. Horm. Metab. Res. 39, 250-255 (2007
-
(2007)
Horm. Metab. Res
, vol.39
, pp. 250-255
-
-
Hector, J.1
-
95
-
-
57349120067
-
Visfatin: A new player in mesangial cell physiology and diabetic nephropathy
-
Song, H. K., et al. Visfatin: a new player in mesangial cell physiology and diabetic nephropathy. Am. J. Physiol. Renal Physiol. 295, F1485-F1494 (2008
-
(2008)
Am. J. Physiol. Renal Physiol
, vol.295
, pp. F1485-F1494
-
-
Song, H.K.1
-
96
-
-
77955050794
-
Visfatin is a positive regulator of mcp 1 in human adipocytes in vitro and in mice in vivo
-
Sommer, G., et al. Visfatin is a positive regulator of MCP 1 in human adipocytes in vitro and in mice in vivo. Obesity (Silver Spring) 18, 1486-1492 (2010
-
(2010)
Obesity (Silver Spring
, vol.18
, pp. 1486-1492
-
-
Sommer, G.1
-
97
-
-
77957226193
-
Visfatin regulates genes related to lipid metabolism in porcine adipocytes
-
Yang, C. C., et al. Visfatin regulates genes related to lipid metabolism in porcine adipocytes. J. Anim. Sci. 88, 3233-3241 (2010
-
(2010)
J. Anim. Sci
, vol.88
, pp. 3233-3241
-
-
Yang, C.C.1
-
98
-
-
84875645961
-
Shift work or food intake during the rest phase promotes metabolic disruption and desynchrony of liver genes in male rats
-
Salgado-Delgado, R. C., et al. Shift work or food intake during the rest phase promotes metabolic disruption and desynchrony of liver genes in male rats. PLoS ONE. 8, e60052 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e60052
-
-
Salgado-Delgado, R.C.1
-
99
-
-
84861324365
-
Circadian desynchrony promotes metabolic disruption in a mouse model of shiftwork
-
Barclay, J. L., et al. Circadian desynchrony promotes metabolic disruption in a mouse model of shiftwork. PLoS ONE. 7, e37150 (2012
-
(2012)
PLoS ONE
, vol.7
, pp. e37150
-
-
Barclay, J.L.1
-
100
-
-
0034771257
-
Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27, 485 people
-
Karlsson, B., Knutsson, A., & Lindahl, B. Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27, 485 people. Occup. Environ. Med. 58, 747-752 (2001
-
(2001)
Occup. Environ. Med
, vol.58
, pp. 747-752
-
-
Karlsson, B.1
Knutsson, A.2
Lindahl, B.3
-
101
-
-
84856781791
-
Diurnal rhythm of circulating nicotinamide phosphoribosyltransferase (nampt/visfatin/pbef): Impact of sleep loss and relation to glucose metabolism
-
Benedict, C., et al. Diurnal rhythm of circulating nicotinamide phosphoribosyltransferase (Nampt/visfatin/PBEF): impact of sleep loss and relation to glucose metabolism. J. Clin. Endocrinol. Metab. 97, E218-E222 (2012
-
(2012)
J. Clin. Endocrinol. Metab
, vol.97
, pp. E218-E222
-
-
Benedict, C.1
-
102
-
-
36248989090
-
Central visfatin causes orexigenic effects in chicks
-
Cline, M. A., Nandar, W., Prall, B. C., Bowden, C. N., & Denbow, D. M. Central visfatin causes orexigenic effects in chicks. Behav. Brain Res. 186, 293-297 (2008
-
(2008)
Behav. Brain Res
, vol.186
, pp. 293-297
-
-
Cline, M.A.1
Nandar, W.2
Prall, B.C.3
Bowden, C.N.4
Denbow, D.M.5
-
103
-
-
84865047520
-
Effects of visfatin/pbef/nampt on feeding behaviour and hypothalamic neuromodulators in the rat
-
Brunetti, L., et al. Effects of visfatin/PBEF/NAMPT on feeding behaviour and hypothalamic neuromodulators in the rat. J. Biol. Regul. Homeost. Agents. 26, 295-302 (2012
-
(2012)
J. Biol. Regul. Homeost. Agents
, vol.26
, pp. 295-302
-
-
Brunetti, L.1
-
104
-
-
84862022077
-
The nad+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity
-
Cantó, C., et al. The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab. 15, 838-847 (2012
-
(2012)
Cell Metab
, vol.15
, pp. 838-847
-
-
Cantó, C.1
-
105
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02300740 (2015
-
(2015)
US National Library of Medicine
-
-
-
106
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02191462 (2015
-
(2015)
US National Library of Medicine
-
-
-
107
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT02303483 (2015
-
(2015)
US National Library of Medicine
-
-
-
108
-
-
84879044408
-
What about non-Alcoholic fatty liver disease as a new criterion to define metabolic syndrome? World J
-
Tarantino, G., & Finelli, C. What about non-Alcoholic fatty liver disease as a new criterion to define metabolic syndrome? World J. Gastroenterol. 19, 3375-3384 (2013
-
(2013)
Gastroenterol
, vol.19
, pp. 3375-3384
-
-
Tarantino, G.1
Finelli, C.2
-
109
-
-
67649911291
-
Influence of visfatin on histopathological changes of non-Alcoholic fatty liver disease
-
Aller, R., et al. Influence of visfatin on histopathological changes of non-Alcoholic fatty liver disease. Dig. Dis. Sci. 54, 1772-1777 (2009
-
(2009)
Dig. Dis. Sci
, vol.54
, pp. 1772-1777
-
-
Aller, R.1
-
110
-
-
84872000593
-
Plasma visfatin levels and gene expression in morbidly obese women with associated fatty liver disease
-
Auguet, T., et al. Plasma visfatin levels and gene expression in morbidly obese women with associated fatty liver disease. Clin. Biochem. 46, 202-208 (2013
-
(2013)
Clin. Biochem
, vol.46
, pp. 202-208
-
-
Auguet, T.1
-
111
-
-
84885737214
-
Association of plasma visfatin with hepatic and systemic inflammation in nonalcoholic fatty liver disease
-
Genc, H., et al. Association of plasma visfatin with hepatic and systemic inflammation in nonalcoholic fatty liver disease. Ann. Hepatol. 12, 548-555 (2013
-
(2013)
Ann. Hepatol
, vol.12
, pp. 548-555
-
-
Genc, H.1
-
112
-
-
84859168943
-
Visfatin levels in nonalcoholic fatty liver disease
-
Akbal, E., Kocak, E., Tas, A., Yuksel, E., & Koklu, S. Visfatin levels in nonalcoholic fatty liver disease. J. Clin. Lab. Anal. 26, 115-119 (2012
-
(2012)
J. Clin. Lab. Anal
, vol.26
, pp. 115-119
-
-
Akbal, E.1
Kocak, E.2
Tas, A.3
Yuksel, E.4
Koklu, S.5
-
113
-
-
77954502566
-
Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease
-
Dahl, T. B., et al. Intracellular nicotinamide phosphoribosyltransferase protects against hepatocyte apoptosis and is down-regulated in nonalcoholic fatty liver disease. J. Clin. Endocrinol. Metab. 95, 3039-3047 (2010
-
(2010)
J. Clin. Endocrinol. Metab
, vol.95
, pp. 3039-3047
-
-
Dahl, T.B.1
-
114
-
-
77958103809
-
Visceral adipose tissue visfatin in nonalcoholic fatty liver disease
-
Gaddipati, R., et al. Visceral adipose tissue visfatin in nonalcoholic fatty liver disease. Ann. Hepatol. 9, 266-270 (2010
-
(2010)
Ann. Hepatol
, vol.9
, pp. 266-270
-
-
Gaddipati, R.1
-
115
-
-
79953269789
-
Liver visfatin expression in morbidly obese patients with nonalcoholic fatty liver disease undergoing bariatric surgery
-
Kukla, M. M., et al. Liver visfatin expression in morbidly obese patients with nonalcoholic fatty liver disease undergoing bariatric surgery. Polish J. Pathol. 61, 147-153 (2010
-
(2010)
Polish J. Pathol
, vol.61
, pp. 147-153
-
-
Kukla, M.M.1
-
116
-
-
84905447695
-
Troxerutin improves hepatic lipid homeostasis by restoring nad+ depletion mediated dysfunction of lipin 1 signaling in high-fat diet-Treated mice
-
Zhang, Z. F., et al. Troxerutin improves hepatic lipid homeostasis by restoring NAD+ depletion mediated dysfunction of lipin 1 signaling in high-fat diet-Treated mice. Biochem. Pharmacol. 91, 74-86 (2014
-
(2014)
Biochem. Pharmacol
, vol.91
, pp. 74-86
-
-
Zhang, Z.F.1
-
117
-
-
84869192260
-
Leucine supplementation increases sirt1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice
-
Li, H., Xu, M., Lee, J., He, C., & Xie, Z. Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice. Am. J. Physiol. Endocrinol. Metab. 303, E1234-E1244 (2012
-
(2012)
Am. J. Physiol. Endocrinol. Metab
, vol.303
, pp. E1234-E1244
-
-
Li, H.1
Xu, M.2
Lee, J.3
He, C.4
Xie, Z.5
-
118
-
-
79954576666
-
Hepatic foxos regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene
-
Tao, R., et al. Hepatic FoxOs regulate lipid metabolism via modulation of expression of the nicotinamide phosphoribosyltransferase gene. J. Biol. Chem. 286, 14681-14690 (2011
-
(2011)
J. Biol. Chem
, vol.286
, pp. 14681-14690
-
-
Tao, R.1
-
119
-
-
84871221881
-
MIR 34a/sirt1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-Alcoholic fatty liver disease
-
Castro, R. E., et al. miR 34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-Alcoholic fatty liver disease. J. Hepatol. 58, 119-125 (2013
-
(2013)
J. Hepatol
, vol.58
, pp. 119-125
-
-
Castro, R.E.1
-
120
-
-
84888131014
-
Elevated microrna 34a in obesity reduces nad+ levels and sirt1 activity by directly targeting nampt
-
Choi, S. E., et al. Elevated microRNA 34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT. Aging Cell. 12, 1062-1072 (2013
-
(2013)
Aging Cell
, vol.12
, pp. 1062-1072
-
-
Choi, S.E.1
-
121
-
-
84922264188
-
Increasing nad synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism
-
Frederick, D. W., et al. Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism. J. Biol. Chem. 290, 1546-1558 (2015
-
(2015)
J. Biol. Chem
, vol.290
, pp. 1546-1558
-
-
Frederick, D.W.1
-
122
-
-
76649085804
-
Deleted in breast cancer 1 regulates sirt1 activity and contributes to high-fat diet-induced liver steatosis in mice
-
Escande, C., et al. Deleted in breast cancer 1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice. J. Clin. Invest. 120, 545-558 (2010
-
(2010)
J. Clin. Invest
, vol.120
, pp. 545-558
-
-
Escande, C.1
-
123
-
-
81155131770
-
Involvement of visfatin in palmitate-induced upregulation of inflammatory cytokines in hepatocytes
-
Choi, Y. J., et al. Involvement of visfatin in palmitate-induced upregulation of inflammatory cytokines in hepatocytes. Metabolism. 60, 1781-1789 (2011
-
(2011)
Metabolism
, vol.60
, pp. 1781-1789
-
-
Choi, Y.J.1
-
124
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn, S. E., Hull, R. L., & Utzschneider, K. M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature. 444, 840-846 (2006
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
125
-
-
84919398877
-
Mechanism linking diabetes mellitus and obesity
-
Al-Goblan, A. S., Al-Alfi, M. A., & Khan, M. Z. Mechanism linking diabetes mellitus and obesity. Diabetes. Metab. Syndr. Obes. 7, 587-591 (2014
-
(2014)
Diabetes. Metab. Syndr. Obes
, vol.7
, pp. 587-591
-
-
Al-Goblan, A.S.1
Al-Alfi, M.A.2
Khan, M.Z.3
-
126
-
-
70449525230
-
Role of adipocytokines in predicting the development of diabetes and its late complications
-
Gulcelik, N. E., Usman, A., & Gürlek, A. Role of adipocytokines in predicting the development of diabetes and its late complications. Endocrine. 36, 397-403 (2009
-
(2009)
Endocrine
, vol.36
, pp. 397-403
-
-
Gulcelik, N.E.1
Usman, A.2
Gürlek, A.3
-
127
-
-
84897114276
-
Adipokines-removing road blocks to obesity and diabetes therapy
-
Blüher, M. Adipokines-removing road blocks to obesity and diabetes therapy. Mol. Metab. 3, 230-240 (2014
-
(2014)
Mol. Metab
, vol.3
, pp. 230-240
-
-
Blüher, M.1
-
128
-
-
12344327355
-
Medicine visfatin: A new adipokine
-
Hug, C., & Lodish, H. F. Medicine. Visfatin: a new adipokine. Science. 307, 366-367 (2005
-
(2005)
Science
, vol.307
, pp. 366-367
-
-
Hug, C.1
Lodish, H.F.2
-
129
-
-
33846991610
-
Human visfatin expression: Relationship to insulin sensitivity, intramyocellular lipids, and inflammation
-
Varma, V., et al. Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation. J. Clin. Endocrinol. Metab. 92, 666-672 (2007
-
(2007)
J. Clin. Endocrinol. Metab
, vol.92
, pp. 666-672
-
-
Varma, V.1
-
130
-
-
84862023845
-
Lipid profiles and serum visfatin concentrations in patients with type II diabetes in comparison with healthy controls
-
Hajianfar, H., Bahonar, A., Entezari, M. H., Askari, G., & Yazdani, M. Lipid profiles and serum visfatin concentrations in patients with type II diabetes in comparison with healthy controls. Int. J. Prev. Med. 3, 326-331 (2012
-
(2012)
Int. J. Prev. Med
, vol.3
, pp. 326-331
-
-
Hajianfar, H.1
Bahonar, A.2
Entezari, M.H.3
Askari, G.4
Yazdani, M.5
-
131
-
-
78649906890
-
Vaspin and visfatin/nampt are interesting interrelated adipokines playing a role in the pathogenesis of type 2 diabetes mellitus
-
El-Mesallamy, H. O., Kassem, D. H., El-Demerdash, E., & Amin, A. I. Vaspin and visfatin/Nampt are interesting interrelated adipokines playing a role in the pathogenesis of type 2 diabetes mellitus. Metabolism. 60, 63-70 (2011
-
(2011)
Metabolism
, vol.60
, pp. 63-70
-
-
El-Mesallamy, H.O.1
Kassem, D.H.2
El-Demerdash, E.3
Amin, A.I.4
-
132
-
-
30344471828
-
Elevated plasma level of visfatin/pre b cell colony-enhancing factor in patients with type 2 diabetes mellitus
-
Chen, M. P., et al. Elevated plasma level of visfatin/pre B cell colony-enhancing factor in patients with type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 91, 295-299 (2006
-
(2006)
J. Clin. Endocrinol. Metab
, vol.91
, pp. 295-299
-
-
Chen, M.P.1
-
133
-
-
33750867485
-
Serum visfatin increases with progressive β cell deterioration
-
Lspez-Bermejo, A., et al. Serum visfatin increases with progressive β cell deterioration. Diabetes. 55, 2871-2875 (2006
-
(2006)
Diabetes
, vol.55
, pp. 2871-2875
-
-
López-Bermejo, A.1
-
134
-
-
37349005462
-
Endothelial dysfunction in type 2 diabetics with early diabetic nephropathy is associated with low circulating adiponectin
-
Yilmaz, M. I., et al. Endothelial dysfunction in type 2 diabetics with early diabetic nephropathy is associated with low circulating adiponectin. Nephrol. Dial. Transplant. 23, 1621-1627 (2008
-
(2008)
Nephrol. Dial. Transplant
, vol.23
, pp. 1621-1627
-
-
Yilmaz, M.I.1
-
135
-
-
84909645726
-
Visfatin -948g/t and resistin -420c/g polymorphisms in egyptian type 2 diabetic patients with and without cardiovascular diseases
-
Motawi, T. M., Shaker, O. G., El-Sawalhi, M. M., & Abdel-Nasser, Z. M. Visfatin -948G/T and resistin -420C/G. polymorphisms in Egyptian type 2 diabetic patients with and without cardiovascular diseases. Genome. 57, 259-266 (2014
-
(2014)
Genome
, vol.57
, pp. 259-266
-
-
Motawi, T.M.1
Shaker, O.G.2
El-Sawalhi, M.M.3
Abdel-Nasser, Z.M.4
-
136
-
-
33947150636
-
Insulin-like effects of visfatin on human osteoblasts
-
Xie, H., et al. Insulin-like effects of visfatin on human osteoblasts. Calcif. Tissue Int. 80, 201-210 (2007
-
(2007)
Calcif. Tissue Int
, vol.80
, pp. 201-210
-
-
Xie, H.1
-
137
-
-
38349112898
-
Age-Associated loss of sirt1-mediated enhancement of glucose-stimulated insulin secretion in β cell-specific sirt1-overexpressing (besto) mice
-
Ramsey, K. M., Mills, K. F., Satoh, A., & Imai, S. I. Age-Associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in β cell-specific Sirt1-overexpressing (BESTO) mice. Aging Cell. 7, 78-88 (2008
-
(2008)
Aging Cell
, vol.7
, pp. 78-88
-
-
Ramsey, K.M.1
Mills, K.F.2
Satoh, A.3
Imai, S.I.4
-
138
-
-
84872431651
-
The adipocytokine nampt and its product nmn have no effect on β cell survival but potentiate glucose stimulated insulin secretion
-
Spinnler, R., et al. The adipocytokine Nampt and its product NMN have no effect on β cell survival but potentiate glucose stimulated insulin secretion. PLoS ONE. 8, e54106 (2013
-
(2013)
PLoS ONE
, vol.8
, pp. e54106
-
-
Spinnler, R.1
-
139
-
-
80053920774
-
Nicotinamide mononucleotide, a key nad+ intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice
-
Yoshino, J., Mills, K. F., Yoon, M. J., & Imai, S. Nicotinamide mononucleotide, a key NAD+ intermediate, treats the pathophysiology of diet- And age-induced diabetes in mice. Cell Metab. 14, 528-536 (2011
-
(2011)
Cell Metab
, vol.14
, pp. 528-536
-
-
Yoshino, J.1
Mills, K.F.2
Yoon, M.J.3
Imai, S.4
-
140
-
-
82455212299
-
Nicotinamide mononucleotide protects against pro-inflammatory cytokine-mediated impairment of mouse islet function
-
Caton, P. W., Kieswich, J., Yaqoob, M. M., Holness, M. J., & Sugden, M. C. Nicotinamide mononucleotide protects against pro-inflammatory cytokine-mediated impairment of mouse islet function. Diabetologia. 54, 3083-3092 (2011
-
(2011)
Diabetologia
, vol.54
, pp. 3083-3092
-
-
Caton, P.W.1
Kieswich, J.2
Yaqoob, M.M.3
Holness, M.J.4
Sugden, M.C.5
-
141
-
-
84904751060
-
And sirtuins in aging and disease
-
Imai, S., & Guarente, L. NAD+ and sirtuins in aging and disease. Trends Cell Biol. 24, 464-471 (2014
-
(2014)
Trends Cell Biol
, vol.24
, pp. 464-471
-
-
Imai, S.1
Nad, G.L.2
-
142
-
-
34249696938
-
Extension of human cell lifespan by nicotinamide phosphoribosyltransferase
-
Van der Veer, E., et al. Extension of human cell lifespan by nicotinamide phosphoribosyltransferase. J. Biol. Chem. 282, 10841-10845 (2007
-
(2007)
J. Biol. Chem
, vol.282
, pp. 10841-10845
-
-
Van Der Veer, E.1
-
143
-
-
84905080601
-
Visfatin/nampt induces telomere damage and senescence in human endothelial cells
-
Villalobos, L. A., et al. Visfatin/Nampt induces telomere damage and senescence in human endothelial cells. Int. J. Cardiol. 175, 573-575 (2014
-
(2014)
Int. J. Cardiol
, vol.175
, pp. 573-575
-
-
Villalobos, L.A.1
-
144
-
-
84890493585
-
Nicotinamide phosphoribosyltransferase is required for the calorie restriction-mediated improvements in oxidative stress, mitochondrial biogenesis, and metabolic adaptation
-
Song, J., et al. Nicotinamide phosphoribosyltransferase is required for the calorie restriction-mediated improvements in oxidative stress, mitochondrial biogenesis, and metabolic adaptation. J. Gerontol. A Biol. Sci. Med. Sci. 69, 44-57 (2014
-
(2014)
J. Gerontol. A Biol. Sci. Med. Sci
, vol.69
, pp. 44-57
-
-
Song, J.1
-
145
-
-
84863328156
-
Age-related cognitive decline: Can neural stem cells help us?
-
Artegiani, B., & Calegari, F. Age-related cognitive decline: can neural stem cells help us? Aging (Albany NY) 4, 176-186 (2012
-
(2012)
Aging (Albany NY
, vol.4
, pp. 176-186
-
-
Artegiani, B.1
Calegari, F.2
-
146
-
-
84903276373
-
Specific ablation of nampt in adult neural stem cells recapitulates their functional defects during aging
-
Stein, L. R., & Imai, S. I. Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging. EMBO J. 33, 1321-1340 (2014
-
(2014)
EMBO J.
, vol.33
, pp. 1321-1340
-
-
Stein, L.R.1
Imai, S.I.2
-
147
-
-
84907968865
-
Relationship between circulating visfatin/nampt, nutritional status and insulin resistance in an elderly population-results from the polsenior substudy
-
Olszanecka-Glinianowicz, M., et al. Relationship between circulating visfatin/NAMPT, nutritional status and insulin resistance in an elderly population-results from the PolSenior substudy. Metabolism. 63, 1409-1418 (2014
-
(2014)
Metabolism
, vol.63
, pp. 1409-1418
-
-
Olszanecka-Glinianowicz, M.1
-
148
-
-
0033911488
-
Inflamm-Aging an evolutionary perspective on immunosenescence
-
Franceschi, C., et al. Inflamm-Aging. An evolutionary perspective on immunosenescence. Ann. NY Acad. Sci. 908, 244-254 (2000
-
(2000)
Ann. NY Acad. Sci
, vol.908
, pp. 244-254
-
-
Franceschi, C.1
-
149
-
-
34547873915
-
TNF a suppresses the expression of clock genes by interfering with e box mediated transcription
-
Cavadini, G., et al. TNF a suppresses the expression of clock genes by interfering with E box mediated transcription. Proc. Natl Acad. Sci. USA. 104, 12843-12848 (2007
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 12843-12848
-
-
Cavadini, G.1
-
150
-
-
0001221508
-
On respiratory impairment in cancer cells
-
Warburg, O. On respiratory impairment in cancer cells. Science. 124, 269-270 (1956
-
(1956)
Science
, vol.124
, pp. 269-270
-
-
Warburg, O.1
-
151
-
-
84867877340
-
The nad metabolome-A key determinant of cancer cell biology
-
Chiarugi, A., Dölle, C., Felici, R., & Ziegler, M. The NAD metabolome-A key determinant of cancer cell biology. Nat. Rev. Cancer. 12, 741-752 (2012
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 741-752
-
-
Chiarugi, A.1
Dölle, C.2
Felici, R.3
Ziegler, M.4
-
152
-
-
84923306335
-
Fk866-induced nampt inhibition activates ampk and downregulates mtor signalling in hepatocarcinoma cells
-
Schuster, S., et al. FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signalling in hepatocarcinoma cells. Biochem. Biophys. Res. Commun. 458, 334-340 (2015
-
(2015)
Biochem. Biophys. Res. Commun
, vol.458
, pp. 334-340
-
-
Schuster, S.1
-
153
-
-
65149084441
-
The nad biosynthesis inhibitor apo866 has potent antitumor activity against hematologic malignancies
-
Nahimana, A., et al. The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies. Blood. 113, 3276-3286 (2009
-
(2009)
Blood
, vol.113
, pp. 3276-3286
-
-
Nahimana, A.1
-
154
-
-
38649096263
-
Anticancer agent chs 828 inhibits cellular synthesis of nad
-
Olesen, U. H., et al. Anticancer agent CHS 828 inhibits cellular synthesis of NAD. Biochem. Biophys. Res. Commun. 367, 799-804 (2008
-
(2008)
Biochem. Biophys. Res. Commun
, vol.367
, pp. 799-804
-
-
Olesen, U.H.1
-
155
-
-
84881367747
-
Medicinal chemistry of nicotinamide phosphoribosyltransferase (nampt) inhibitors
-
Galli, U., et al. Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors. J. Med. Chem. 56, 6279-6296 (2013
-
(2013)
J. Med. Chem
, vol.56
, pp. 6279-6296
-
-
Galli, U.1
-
156
-
-
84906691644
-
Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrence-free survival in lung and breast cancers
-
Zhou, T., Wang, T., & Garcia, J. G. Expression of nicotinamide phosphoribosyltransferase-influenced genes predicts recurrence-free survival in lung and breast cancers. Sci. Rep. 4, 6107 (2014
-
(2014)
Sci. Rep
, vol.4
, pp. 6107
-
-
Zhou, T.1
Wang, T.2
Garcia, J.G.3
-
157
-
-
84868588684
-
Targeting nad+ salvage pathway induces autophagy in multiple myeloma cells via mtorc1 and extracellular signal-regulated kinase (erk1/2) inhibition
-
Cea, M., et al. Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition. Blood. 120, 3519-3529 (2012
-
(2012)
Blood
, vol.120
, pp. 3519-3529
-
-
Cea, M.1
-
158
-
-
84871362358
-
Involvement of p53 in the cytotoxic activity of the nampt inhibitor fk866 in myeloid leukemic cells
-
Thakur, B. K., et al. Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells. Int. J. Cancer. 132, 766-774 (2013
-
(2013)
Int. J. Cancer
, vol.132
, pp. 766-774
-
-
Thakur, B.K.1
-
159
-
-
84902969536
-
Genetic variants in nampt predict bladder cancer risk and prognosis in individuals from southwest Chinese han group
-
Zhang, K., et al. Genetic variants in NAMPT predict bladder cancer risk and prognosis in individuals from southwest Chinese Han group. Tumour Biol. 35, 4031-4040 (2014
-
(2014)
Tumour Biol
, vol.35
, pp. 4031-4040
-
-
Zhang, K.1
-
160
-
-
84877574703
-
Visfatin, a potential biomarker and prognostic factor for endometrial cancer
-
Tian, W., et al. Visfatin, a potential biomarker and prognostic factor for endometrial cancer. Gynecol. Oncol. 129, 505-512 (2013
-
(2013)
Gynecol. Oncol
, vol.129
, pp. 505-512
-
-
Tian, W.1
-
161
-
-
56149120031
-
Pbef1/namprtase/visfatin: A potential malignant astrocytoma/glioblastoma serum marker with prognostic value
-
Reddy, P. S., et al. PBEF1/NAmPRTase/Visfatin: a potential malignant astrocytoma/glioblastoma serum marker with prognostic value. Cancer Biol. Ther. 7, 663-668 (2008
-
(2008)
Cancer Biol. Ther
, vol.7
, pp. 663-668
-
-
Reddy, P.S.1
-
162
-
-
83055174653
-
Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells
-
Ninomiya, S., et al. Possible role of visfatin in hepatoma progression and the effects of branched-chain amino acids on visfatin-induced proliferation in human hepatoma cells. Cancer Prev. Res. (Phila.) 4, 2092-2100 (2011
-
(2011)
Cancer Prev. Res. (Phila
, vol.4
, pp. 2092-2100
-
-
Ninomiya, S.1
-
163
-
-
84920581665
-
Extracellular nicotinamide phosphoribosyltransferase (nampt) promotes m2 macrophage polarization in chronic lymphocytic leukemia
-
Audrito, V., et al. Extracellular nicotinamide phosphoribosyltransferase (NAMPT) promotes M2 macrophage polarization in chronic lymphocytic leukemia. Blood. 125, 111-123 (2015
-
(2015)
Blood
, vol.125
, pp. 111-123
-
-
Audrito, V.1
-
164
-
-
84872763359
-
Visfatin affects redox adaptative responses and proliferation in me45 human malignant melanoma cells: An in vitro study
-
Bułdak, R. J., et al. Visfatin affects redox adaptative responses and proliferation in Me45 human malignant melanoma cells: an in vitro study. Oncol. Rep. 29, 771-778 (2013
-
(2013)
Oncol. Rep
, vol.29
, pp. 771-778
-
-
Bułdak, R.J.1
-
165
-
-
42349084337
-
Visfatin induces human endothelial vegf and mmp 2/9 production via mapk and pi3k/akt signalling pathways: Novel insights into visfatin-induced angiogenesis
-
Adya, R., Tan, B. K., Punn, A., Chen, J., & Randeva, H. S. Visfatin induces human endothelial VEGF and MMP 2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis. Cardiovasc. Res. 78, 356-365 (2008
-
(2008)
Cardiovasc. Res
, vol.78
, pp. 356-365
-
-
Adya, R.1
Tan, B.K.2
Punn, A.3
Chen, J.4
Randeva, H.S.5
-
166
-
-
78649947146
-
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase
-
Olesen, U. H., et al. Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase. BMC Cancer. 10, 677 (2010
-
(2010)
BMC Cancer
, vol.10
, pp. 677
-
-
Olesen, U.H.1
-
167
-
-
80053142651
-
Overexpression of nampt in gastric cancer and chemopotentiating effects of the nampt inhibitor fk866 in combination with fluorouracil
-
Bi, T. Q., et al. Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracil. Oncol. Rep. 26, 1251-1257 (2011
-
(2011)
Oncol. Rep
, vol.26
, pp. 1251-1257
-
-
Bi, T.Q.1
-
168
-
-
84907907895
-
On-Target effect of fk866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells
-
Gehrke, I., et al. On-Target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells. Clin. Cancer Res. 20, 4861-4872 (2014
-
(2014)
Clin. Cancer Res
, vol.20
, pp. 4861-4872
-
-
Gehrke, I.1
-
169
-
-
67651083680
-
Apo866 activity in hematologic malignancies: A preclinical in vitro study
-
Cea, M., et al. APO866 activity in hematologic malignancies: a preclinical in vitro study. Blood. 113, 6035-6037 (2009
-
(2009)
Blood
, vol.113
, pp. 6035-6037
-
-
Cea, M.1
-
170
-
-
84918577739
-
Nicotinamide phosphoribosyltransferase promotes epithelial to mesenchymal transition as a soluble factor independent of its enzymatic activity
-
Soncini, D., et al. Nicotinamide phosphoribosyltransferase promotes epithelial to mesenchymal transition as a soluble factor independent of its enzymatic activity. J. Biol. Chem. 289, 34189-34204 (2014
-
(2014)
J. Biol. Chem
, vol.289
, pp. 34189-34204
-
-
Soncini, D.1
-
171
-
-
84873291018
-
Pharmacological inhibition of nicotinamide phosphoribosyltransferase (nampt), an enzyme essential for nad+ biosyn
-
thesis, in human cancer cells: metabolic basis and potential clinical implications
-
Tan, B., et al. Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications. J. Biol. Chem. 288, 3500-3511 (2013
-
(2013)
J. Biol. Chem
, vol.288
, pp. 3500-3511
-
-
Tan, B.1
-
172
-
-
84919497464
-
Inhibition of de novo nad+ synthesis by oncogenic uri causes liver tumorigenesis through DNA damage
-
Tummala, K. S., et al. Inhibition of de novo NAD+ synthesis by oncogenic URI causes liver tumorigenesis through DNA damage. Cancer Cell. 26, 826-839 (2014
-
(2014)
Cancer Cell
, vol.26
, pp. 826-839
-
-
Tummala, K.S.1
-
173
-
-
77951887249
-
Safetyfsti and efficacy of nad depleting cancer drugs: Results of a phase i clinical trial of chs 828 and overview of published data
-
Von Heideman, A., Berglund, A., Larsson, R., & Nygren, P. Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data. Cancer Chemother. Pharmacol. 65, 1165-1172 (2010
-
(2010)
Cancer Chemother. Pharmacol
, vol.65
, pp. 1165-1172
-
-
Von Heideman, A.1
Berglund, A.2
Larsson, R.3
Nygren, P.4
-
174
-
-
38149105811
-
The pharmacokinetics, toxicities, and biologic effects of fk866, a nicotinamide adenine dinucleotide biosynthesis inhibitor
-
Holen, K., Saltz, L. B., Hollywood, E., Burk, K., & Hanauske, A. R. The pharmacokinetics, toxicities, and biologic effects of FK866, a nicotinamide adenine dinucleotide biosynthesis inhibitor. Invest. New Drugs. 26, 45-51 (2008
-
(2008)
Invest. New Drugs
, vol.26
, pp. 45-51
-
-
Holen, K.1
Saltz, L.B.2
Hollywood, E.3
Burk, K.4
Hanauske, A.R.5
-
175
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00003979 (2015
-
(2015)
US National Library of Medicine
-
-
-
176
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00724841 (2015
-
(2015)
US National Library of Medicine
-
-
-
177
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00457574 (2015
-
(2015)
US National Library of Medicine
-
-
-
178
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00431912 (2015
-
(2015)
US National Library of Medicine
-
-
-
179
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00435084 (2015
-
(2015)
US National Library of Medicine
-
-
-
180
-
-
84861726854
-
-
ClinicalTrials.gov [online
-
US National Library of Medicine. ClinicalTrials.gov [online], https://clinicaltrials.gov/ct2/show/NCT00432107 (2015
-
(2015)
US National Library of Medicine
-
-
-
181
-
-
84909620040
-
Synergy between the nampt inhibitor gmx1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by parp activation and enhanced nad consumption
-
Chan, M., et al. Synergy between the NAMPT inhibitor GMX1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption. Cancer Res. 74, 5948-5954 (2014
-
(2014)
Cancer Res
, vol.74
, pp. 5948-5954
-
-
Chan, M.1
-
182
-
-
84877290100
-
Effect of weight reduction following bariatric surgery on serum visfatin and adiponectin levels in morbidly obese subjects
-
Hosseinzadeh-Attar, M. J., Golpaie, A., Janani, L., & Derakhshanian, H. Effect of weight reduction following bariatric surgery on serum visfatin and adiponectin levels in morbidly obese subjects. Obes. Facts. 6, 193-202 (2013
-
(2013)
Obes. Facts
, vol.6
, pp. 193-202
-
-
Hosseinzadeh-Attar, M.J.1
Golpaie, A.2
Janani, L.3
Derakhshanian, H.4
-
183
-
-
84988452878
-
The comparison of serum vaspin and visfatin concentrations in obese and normal weight women
-
Saboori, S., et al. The comparison of serum vaspin and visfatin concentrations in obese and normal weight women. Diabetes Metab. Syndr. http://dx.doi.org/10.1016/j.dsx.2013.10.009
-
Diabetes Metab. Syndr
-
-
Saboori, S.1
-
184
-
-
84878322290
-
Elevated visfatin levels in obese children are related to proinflammatory factors
-
Li, R. Z., et al. Elevated visfatin levels in obese children are related to proinflammatory factors. J. Pediatr. Endocrinol. Metab. 26, 111-118 (2013
-
(2013)
J. Pediatr. Endocrinol. Metab
, vol.26
, pp. 111-118
-
-
Li, R.Z.1
-
185
-
-
84884561464
-
Association of adipokines with obesity in children and adolescents
-
Jaleel, A., et al. Association of adipokines with obesity in children and adolescents. Biomark. Med. 7, 731-735 (2013
-
(2013)
Biomark. Med
, vol.7
, pp. 731-735
-
-
Jaleel, A.1
-
186
-
-
84867263517
-
Increased levels and adipose tissue expression of visfatin in morbidly obese women: The relationship with pro-inflammatory cytokines
-
Terra, X., et al. Increased levels and adipose tissue expression of visfatin in morbidly obese women: the relationship with pro-inflammatory cytokines. Clin. Endocrinol. (Oxf.) 77, 691-698 (2012
-
(2012)
Clin. Endocrinol. (Oxf
, vol.77
, pp. 691-698
-
-
Terra, X.1
-
187
-
-
84862901483
-
Serum visfatin levels, adiposity and glucose metabolism in obese adolescents
-
Taskesen, D., Kirel, B., & Us, T. Serum visfatin levels, adiposity and glucose metabolism in obese adolescents. J. Clin. Res. Pediatr. Endocrinol. 4, 76-81 (2012
-
(2012)
J. Clin. Res. Pediatr. Endocrinol
, vol.4
, pp. 76-81
-
-
Taskesen, D.1
Kirel, B.2
Us, T.3
-
188
-
-
79952702085
-
Association of increased visfatin/pbef/nampt circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity
-
Catalan, V., et al. Association of increased visfatin/PBEF/NAMPT circulating concentrations and gene expression levels in peripheral blood cells with lipid metabolism and fatty liver in human morbid obesity. Nutr. Metab. Cardiovasc. Dis. 21, 245-253 (2011
-
(2011)
Nutr. Metab. Cardiovasc. Dis
, vol.21
, pp. 245-253
-
-
Catalan, V.1
-
189
-
-
84868647921
-
Serum visfatin levels in a group of egyptian obese individuals
-
Reda, R., Shehab, A., Soliman, D., Gabr, A., & Abbass, A. Serum visfatin levels in a group of Egyptian obese individuals. Egypt. J. Immunol. 18, 25-32 (2011
-
(2011)
Egypt. J. Immunol
, vol.18
, pp. 25-32
-
-
Reda, R.1
Shehab, A.2
Soliman, D.3
Gabr, A.4
Abbass, A.5
-
190
-
-
81255214946
-
Visfatin in juvenile obesity-The effect of obesity intervention and sex
-
Krzystek-Korpacka, M., Patryn, E., Bednarz-Misa, I., Hotowy, K., & Noczynska, A. Visfatin in juvenile obesity-The effect of obesity intervention and sex. Eur. J. Clin. Invest. 41, 1284-1291 (2011
-
(2011)
Eur. J. Clin. Invest
, vol.41
, pp. 1284-1291
-
-
Krzystek-Korpacka, M.1
Patryn, E.2
Bednarz-Misa, I.3
Hotowy, K.4
Noczynska, A.5
-
191
-
-
80053970864
-
Serum visfatin and vaspin levels in prepubertal children: Effect of obesity and weight loss after behavior modifications on their secretion and relationship with glucose metabolism
-
Martos-Moreno, G. Á., et al. Serum visfatin and vaspin levels in prepubertal children: effect of obesity and weight loss after behavior modifications on their secretion and relationship with glucose metabolism. Int. J. Obes. (Lond.) 35, 1355-1362 (2011
-
(2011)
Int. J. Obes. (Lond
, vol.35
, pp. 1355-1362
-
-
Martos-Moreno, G.Á.1
-
192
-
-
75449085490
-
Body fat distribution has no effect on serum visfatin levels in healthy female subjects
-
Ersoy, C., et al. Body fat distribution has no effect on serum visfatin levels in healthy female subjects. Cytokine. 49, 275-278 (2010
-
(2010)
Cytokine
, vol.49
, pp. 275-278
-
-
Ersoy, C.1
-
193
-
-
77953514528
-
An evaluation of visfatin levels in obese subjects
-
Kaminska, A., et al. An evaluation of visfatin levels in obese subjects. Endokrynol. Pol. 61, 169-173 (2010
-
(2010)
Endokrynol. Pol
, vol.61
, pp. 169-173
-
-
Kaminska, A.1
-
194
-
-
77956555952
-
Expression of neuropeptide y, omentin and visfatin in visceral and subcutaneous adipose tissues in humans: Relation to endocrine and clinical parameters
-
Barth, S., et al. Expression of neuropeptide Y, omentin and visfatin in visceral and subcutaneous adipose tissues in humans: relation to endocrine and clinical parameters. Obes. Facts. 3, 245-251 (2010
-
(2010)
Obes. Facts
, vol.3
, pp. 245-251
-
-
Barth, S.1
-
195
-
-
73649133942
-
Skeletal muscle nampt is induced by exercise in humans
-
Costford, S. R., et al. Skeletal muscle NAMPT is induced by exercise in humans. Am. J. Physiol. Endocrinol. Metab. 298, E117-E126 (2010
-
(2010)
Am. J. Physiol. Endocrinol. Metab
, vol.298
, pp. E117-E126
-
-
Costford, S.R.1
-
196
-
-
33745894354
-
Regulation of pre b cell colony-enhancing factor by stat 3 dependent interleukin 6 trans-signaling: Implications in the pathogenesis of rheumatoid arthritis
-
Nowell, M. A., et al. Regulation of pre B cell colony-enhancing factor by STAT 3 dependent interleukin 6 trans-signaling: implications in the pathogenesis of rheumatoid arthritis. Arthritis Rheum. 54, 2084-2095 (2006
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2084-2095
-
-
Nowell, M.A.1
-
197
-
-
33745826960
-
Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor 1
-
Bae, S. K., et al. Hypoxic induction of human visfatin gene is directly mediated by hypoxia-inducible factor 1. FEBS Lett. 580, 4105-4113 (2006
-
(2006)
Febs lett
, vol.580
, pp. 4105-4113
-
-
Bae, S.K.1
|